1 | PRPF19
|
| PRPF19 modulates morphology and growth behavior in a cell culture model of human skin
|
| Kleissl L, Weinmüllner R, Lämmermann I, Dingelmaier-Hovorka R, Jafarmadar M, El Ghalbzouri A, Stary G, Grillari J, Dellago H.
|
| Front Aging May 5;4:1154005. doi: 10.3389/fragi.2023.1154005. 2023
|
2 | MDM4, PRPF19, TP53
|
| PRPF19 regulates p53-dependent cellular senescence by modulating alternative splicing of MDM4 mRNA
|
| Yano K, Takahashi RU, Shiotani B, Abe J, Shidooka T, Sudo Y, Yamamoto Y, Kan S, Sakagami H, Tahara H.
|
| J Biol Chem. Jul;297(1):100882. doi: 10.1016/j.jbc.2021.100882. Epub 2021 Jun 16. 2021
|
3 | PRPF19
|
| Crystal structure of the WD40 domain of human PRPF19
|
| Zhang Y, Li Y, Liang X, Zhu Z, Sun H, He H, Min J, Liao S, Liu Y.
|
| Biochem Biophys Res Commun. Nov 25;493(3):1250-1253. doi: 10.1016/j.bbrc.2017.09.145. Epub 2017 Sep 28. 2017
|
4 | PRPF19
|
| Prp19 Arrests Cell Cycle via Cdc5L in Hepatocellular Carcinoma Cells
|
| Huang R, Xue R, Qu D, Yin J, Shen XZ.
|
| Int J Mol Sci. Apr 7;18(4):778. doi: 10.3390/ijms18040778 2017
|
5 | PRPF19
|
| Prp19 facilitates invasion of hepatocellular carcinoma via p38 mitogen-activated protein kinase/twist1 pathway.
|
| Yin J, Wang L, Zhu JM, Yu Q, Xue RY, Fang Y, Zhang YA, Chen YJ, Liu TT, Dong L, Shen XZ.
|
| Oncotarget. Apr 19;7(16):21939-51. doi: 10.18632/oncotarget.7877 2016
|
6 | BCAS2, PRPF19, RPA1
|
| The PSO4 protein complex associates with replication protein A (RPA) and modulates the activation of ataxia telangiectasia-mutated and Rad3-related (ATR).
|
| Wan L, Huang J.
|
| J Biol Chem 289(10):6619-26. doi: 10.1074/jbc.M113.543439. Epub 2014 Jan 17. 2014
|
7 | PRPF19
|
| The Prp19 complex directly functions in mitotic spindle assembly.
|
| Hofmann JC, Tegha-Dunghu J, Dräger S, Will CL, Lührmann R, Gruss OJ.
|
| PLoS One 8(9):e74851. doi: 10.1371/journal.pone.0074851. eCollection 2013.
2013
|
8 | CCDC94, PRPF19
|
| Ccdc94 protects cells from ionizing radiation by inhibiting the expression of p53.
|
| Sorrells S, Carbonneau S, Harrington E, Chen AT, Hast B, Milash B, Pyati U, Major MB, Zhou Y, Zon LI, Stewart RA, Look AT, Jette C.
|
| PLoS Genet 8(8):e1002922. doi: 10.1371/journal.pgen.1002922. Epub 2012 Aug 30.
2012
|
9 | DHX15, PRPF19, RBM5
|
| Tumor suppressor RBM5 directly interacts with the DExD/H-box protein DHX15 and stimulates its helicase activity.
|
| Niu Z, Jin W, Zhang L, Li X.
|
| FEBS Lett 586(7):977-83. doi: 10.1016/j.febslet.2012.02.052. Epub 2012 Mar 8.
2012
|
10 | AICDA, CTNNBL1, PRPF19, PRPF31
|
| CTNNBL1 is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L and Prp31.
|
| Ganesh K, Adam S, Taylor B, Simpson P, Rada C, Neuberger M.
|
| J Biol Chem 286(19):17091-102. Epub 2011 Mar 8.
2011
|
11 | PRPF19, U2AF2
|
| The RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65-Prp19 complex.
|
| David CJ, Boyne AR, Millhouse SR, Manley JL.
|
| Genes Dev 25(9):972-83.
2011
|
12 | PRPF19
|
| The Prp19 complex is a novel transcription elongation factor required for TREX occupancy at transcribed genes.
|
| Chanarat S, Seizl M, Strässer K.
|
| Genes Dev 25(11):1147-58. doi: 10.1101/gad.623411. Epub 2011 May 16.
2011
|
13 | CDC5L, EXOC7, PRPF19
|
| Exo70, a subunit of the exocyst complex, interacts with SNEV(hPrp19/hPso4) and is involved in pre-mRNA splicing.
|
| Dellago H, Löscher M, Ajuh P, Ryder U, Kaisermayer C, Grillari-Voglauer R, Fortschegger K, Gross S, Gstraunthaler A, Borth N, Eisenhaber F, Lamond AI, Grillari J.
|
| Biochem J 438(1):81-91.
2011
|
14 | CDKN1A, DHX8, PRPF19, SNW1
|
| SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing.
|
| Chen Y, Zhang L, Jones KA.
|
| Genes Dev 25(7):701-16. doi: 10.1101/gad.2002611.
2011
|
15 | CDC5L, PRPF19
|
| Molecular architecture of the human Prp19/CDC5L complex.
|
| Grote M, Wolf E, Will CL, Lemm I, Agafonov DE, Schomburg A, Fischle W, Urlaub H, Lührmann R.
|
| Mol Cell Biol 30(9):2105-19. Epub 2010 Feb 22.
2010
|
16 | PRPF19, PRPF3, USP4
|
| The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome.
|
| Song EJ, Werner SL, Neubauer J, Stegmeier F, Aspden J, Rio D, Harper JW, Elledge SJ, Kirschner MW, Rape M.
|
| Genes Dev 24(13):1434-47. 2010
|
17 | EGLN3, PRPF19
|
| Human PRP19 interacts with prolyl-hydroxylase PHD3 and inhibits cell death in hypoxia.
|
| Sato M, Sakota M, Nakayama K.
|
| Exp Cell Res 316(17):2871-82. Epub 2010 Jun 30. 2010
|
18 | PRPF19, SETMAR
|
| Regulation of Metnase's TIR binding activity by its binding partner, Pso4.
|
| Beck BD, Lee SS, Hromas R, Lee SH.
|
| Arch Biochem Biophys 498(2):89-94. Epub 2010 Apr 20.
2010
|
19 | BCAS2, CDC5L, PRPF19
|
| Molecular architecture of the human Prp19/CDC5L complex.
|
| Grote M, Wolf E, Will CL, Lemm I, Agafonov DE, Schomburg A, Fischle W, Urlaub H, Lührmann R.
|
| Mol Cell Biol 30(9):2105-19. doi: 10.1128/MCB.01505-09. Epub 2010 Feb 22.
2010
|
20 | AICDA, CDC5L, CTNNBL1, PRPF19
|
| Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1.
|
| Conticello SG, Ganesh K, Xue K, Lu M, Rada C, Neuberger MS.
|
| Mol Cell 31(4):474-84.
2008
|
21 | PRPF19, SETMAR
|
| Human Pso4 is a metnase (SETMAR)-binding partner that regulates metnase function in DNA repair.
|
| Beck BD, Park SJ, Lee YJ, Roman Y, Hromas RA, Lee SH.
|
| J Biol Chem 283(14):9023-30. Epub 2008 Feb 8.
2008
|
22 | HPFH, HBG1, PRPF19, GTF2F1
|
| Purification and identification of proteins that bind to the hereditary persistence of fetal hemoglobin -198 mutation in the gamma-globin gene promoter.
|
| Olave IA, Doneanu C, Fang X, Stamatoyannopoulos G, Li Q.
|
| J Biol Chem 282(2):853-62. Epub 2006 Nov 17. 2007
|
23 | PRPF19
|
| The Prp19/Pso4 core complex undergoes ubiquitylation and structural alterations in response to DNA damage.
|
| Lu X, Legerski RJ.
|
| Biochem Biophys Res Commun 354(4):968-74. Epub 2007 Jan 26. 2007
|
24 | PRPF19
|
| Early embryonic lethality of mice lacking the essential protein SNEV.
|
| Fortschegger K, Wagner B, Voglauer R, Katinger H, Sibilia M, Grillari J.
|
| Mol Cell Biol 27(8):3123-30. Epub 2007 Feb 5. 2007
|
25 | PRPF19
|
| Identification of the domains required for the localization of Prp19p to lipid droplets or the nucleus.
|
| Cho SY, Park PJ, Lee JH, Kim JJ, Lee TR.
|
| Biochem Biophys Res Commun 364(4):844-9. Epub 2007 Oct 25.
2007
|
26 | PRPF19
|
| SNEV overexpression extends the life span of human endothelial cells.
|
| Voglauer R, Chang MW, Dampier B, Wieser M, Baumann K, Sterovsky T, Schreiber M, Katinger H, Grillari J.
|
| Exp Cell Res 312(6):746-59. Epub 2006 Jan 4. 2006
|
27 | PRPF19
|
| The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links.
|
| Zhang N, Kaur R, Lu X, Shen X, Li L, Legerski RJ.
|
| J Biol Chem 280(49):40559-67. Epub 2005 Oct 12. 2005
|
28 | PRPF19
|
| SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly.
|
| Grillari J, Ajuh P, Stadler G, Loscher M, Voglauer R, Ernst W, Chusainow J, Eisenhaber F, Pokar M, Fortschegger K, Grey M, Lamond AI, Katinger H.
|
| Nucleic Acids Res 33(21):6868-83. Print 2005. 2005
|
29 | PRPF19, PSMB4
|
| Interaction of U-box E3 ligase SNEV with PSMB4, the beta7 subunit of the 20 S proteasome.
|
| Löscher M, Fortschegger K, Ritter G, Wostry M, Voglauer R, Schmid JA, Watters S, Rivett AJ, Ajuh P, Lamond AI, Katinger H, Grillari J.
|
| Biochem J 388(Pt 2):593-603.
2005
|