1 | CRTC2, PRMT6
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| Arginine methylation of CRTC2 is critical in the transcriptional control of hepatic glucose metabolism.
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| Han HS, Jung CY, Yoon YS, Choi S, Choi D, Kang G, Park KG, Kim ST, Koo SH.
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| Sci Signal 7(314):ra19. doi: 10.1126/scisignal.2004479.
2014
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2 | PELP1, PRMT6
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| PELP1 oncogenic functions involve alternative splicing via PRMT6.
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| Mann M, Zou Y, Chen Y, Brann D, Vadlamudi R.
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| Mol Oncol 8(2):389-400. doi: 10.1016/j.molonc.2013.12.012. Epub 2013 Dec 30.
2014
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3 | PRMT6, THBS1
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| PRMT6 overexpression upregulates TSP-1 and downregulates MMPs: its implication in motility and invasion.
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| Kim NH, Kim SN, Seo DW, Han JW, Kim YK.
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| Biochem Biophys Res Commun 432(1):60-5. doi: 10.1016/j.bbrc.2013.01.085. Epub 2013 Feb 1.
2013
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4 | PRMT6
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| Differential regulation of MHCII genes by PRMT6, via an AT-hook motif of RFX5.
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| Stavride P, Arampatzi P, Papamatheakis J.
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| Mol Immunol 56(4):390-398. doi: 10.1016/j.molimm.2013.05.235. [Epub ahead of print]
2013
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5 | HMGA1, PRMT6
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| Identification and characterization of new molecular partners for the protein arginine methyltransferase 6 (PRMT6).
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| Lo Sardo A, Altamura S, Pegoraro S, Maurizio E, Sgarra R, Manfioletti G.
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| PLoS One 8(1):e53750. doi: 10.1371/journal.pone.0053750. Epub 2013 Jan 10.
2013
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6 | PRMT6, RFX5
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| Differential regulation of MHCII genes by PRMT6, via an AT-hook motif of RFX5.
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| Stavride P, Arampatzi P, Papamatheakis J.
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| Mol Immunol 56(4):390-8. doi: 10.1016/j.molimm.2013.05.235. Epub 2013 Aug 1.
2013
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7 | PRMT6
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| Cell cycle regulation by the PRMT6 arginine methyltransferase through repression of cyclin-dependent kinase inhibitors.
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| Kleinschmidt MA, de Graaf P, van Teeffelen HA, Timmers HT.
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| PLoS One 7(8):e41446. doi: 10.1371/journal.pone.0041446. Epub 2012 Aug 20.
2012
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8 | PRMT6
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| The arginine methyltransferase PRMT6 regulates cell proliferation and senescence through transcriptional repression of tumor suppressor genes.
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| Stein C, Riedl S, Rüthnick D, Nötzold RR, Bauer UM.
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| Nucleic Acids Res 40(19):9522-33. doi: 10.1093/nar/gks767. Epub 2012 Aug 16.
2012
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9 | PRMT6
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| Ablation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressor.
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| Neault M, Mallette FA, Vogel G, Michaud-Levesque J, Richard S.
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| Nucleic Acids Res 40(19):9513-21. doi: 10.1093/nar/gks764. Epub 2012 Aug 16.
2012
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10 | PRMT6
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| Protein arginine methyltransferase 6 regulates embryonic stem cell identity.
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| Lee YH, Ma H, Tan TZ, Ng SS, Soong R, Mori S, Fu XY, Zernicka-Goetz M, Wu Q.
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| Stem Cells Dev 21(14):2613-22. doi: 10.1089/scd.2011.0330. Epub 2012 May 8.
2012
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11 | PRMT6
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| Kinetic mechanism of protein arginine methyltransferase 6 (PRMT6).
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| Obianyo O, Thompson PR.
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| J Biol Chem 287(8):6062-71. doi: 10.1074/jbc.M111.333609. Epub 2012 Jan 3.
2012
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12 | PRMT1, PRMT6
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| Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
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| Yoshimatsu M, Toyokawa G, Hayami S, Unoki M, Tsunoda T, Field HI, Kelly JD, Neal DE, Maehara Y, Ponder BA, Nakamura Y, Hamamoto R.
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| Int J Cancer 128(3):562-73. doi: 10.1002/ijc.25366.
2011
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13 | PRMT6
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| Protein arginine methyltransferase 6 regulates multiple aspects of gene expression.
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| Harrison MJ, Tang YH, Dowhan DH.
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| Nucleic Acids Res ucleic Acids Res. 2010 Jan 4. [Epub ahead of print]PMID: 20047962 2010
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14 | PRMT6, THBS1
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| Thrombospondin-1 is a transcriptional repression target of PRMT6.
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| Michaud-Levesque J, Richard S.
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| J Biol Chem 284(32):21338-46. Epub 2009 Jun 9.PMID: 19509293 2009
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15 | PRMT6
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| PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation.
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| Hyllus D, Stein C, Schnabel K, Schiltz E, Imhof A, Dou Y, Hsieh J, Bauer UM.
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| Genes Dev 21(24):3369-80.PMID: 18079182 2007
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16 | PRMT6
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| Arginine methylation regulates DNA polymerase beta.
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| El-Andaloussi N, Valovka T, Toueille M, Steinacher R, Focke F, Gehrig P, Covic M, Hassa PO, Schär P, Hübscher U, Hottiger MO.
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| Mol Cell 22(1):51-62.PMID: 16600869 2006
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17 | PRMT6
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| Methylation of Tat by PRMT6 regulates human immunodeficiency virus type 1 gene expression.
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| Boulanger MC, Liang C, Russell RS, Lin R, Bedford MT, Wainberg MA, Richard S.
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| J Virol 79(1):124-31. 2005
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18 | HMGA1, PRMT6
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| Protein arginine methyltransferase 6 specifically methylates the nonhistone chromatin protein HMGA1a.
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| Miranda TB, Webb KJ, Edberg DD, Reeves R, Clarke S.
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| Biochem Biophys Res Commun 336(3):831-5.PMID: 16157300 2005
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19 | PRMT6, CARM1
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| The novel human protein arginine N-methyltransferase PRMT6 is a nuclear enzyme displaying unique substrate specificity.
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| Frankel A, Yadav N, Lee J, Branscombe TL, Clarke S, Bedford MT.
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| J Biol Chem 277(5):3537-43. Epub 2001 Nov 27. 2002
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