Citations for
1FOXG1, PRKD1, RTTL1
14q12 microdeletions excluding FOXG1 give rise to a congenital variant Rett syndrome-like phenotype.
Ellaway CJ, Ho G, Bettella E, Knapman A, Collins F, Hackett A, McKenzie F, Darmanian A, Peters GB, Fagan K, Christodoulou J.
Eur J Hum Genet 21(5):522-7. doi: 10.1038/ejhg.2012.208. Epub 2012 Sep 12. 2013
2DEL14Q12, FOXG1, PRKD1
14q12 and severe Rett-like phenotypes: new clinical insights and physical mapping of FOXG1-regulatory elements.
Allou L, Lambert L, Amsallem D, Bieth E, Edery P, Destrée A, Rivier F, Amor D, Thompson E, Nicholl J, Harbord M, Nemos C, Saunier A, Moustaïne A, Vigouroux A, Jonveaux P, Philippe C.
Eur J Hum Genet 20(12):1216-23. doi: 10.1038/ejhg.2012.127. Epub 2012 Jun 27. 2012
3PRKD1, PRKD2, PRKD3, RHOA, RTKN
Protein kinase D regulates RhoA activity via rhotekin phosphorylation.
Pusapati GV, Eiseler T, Rykx A, Vandoninck S, Derua R, Waelkens E, Van Lint J, von Wichert G, Seufferlein T.
J Biol Chem 287(12):9473-83. doi: 10.1074/jbc.M112.339564. Epub 2012 Jan 6. 2012
4PRKD1, PRKD2
Protein kinase D isoforms are activated in an agonist-specific manner in cardiomyocytes.
Guo J, Gertsberg Z, Ozgen N, Sabri A, Steinberg SF.
J Biol Chem 286(8):6500-9. Epub 2010 Dec 14. 2011
5DLC1, PRKD1
The tumor suppressor protein DLC1 is regulated by PKD-mediated GAP domain phosphorylation.
Scholz RP, Gustafsson JO, Hoffmann P, Jaiswal M, Ahmadian MR, Eisler SA, Erlmann P, Schmid S, Hausser A, Olayioye MA.
Exp Cell Res 317(4):496-503. Epub 2010 Nov 16. 2011
6OSBP, PRKD1
Protein kinase D negatively regulates hepatitis C virus secretion through phosphorylation of oxysterol-binding protein and ceramide transfer protein.
Amako Y, Syed GH, Siddiqui A.
J Biol Chem 286(13):11265-74. doi: 10.1074/jbc.M110.182097. Epub 2011 Feb 1. 2011
7CACNA1C, PRKD1
Protein kinase D regulates the human cardiac L-type voltage-gated calcium channel through serine 1884.
Aita Y, Kurebayashi N, Hirose S, Maturana AD.
FEBS Lett 585(24):3903-6. doi: 10.1016/j.febslet.2011.11.011. Epub 2011 Nov 16. 2011
8PRKD1
A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase.
Monovich L, Vega RB, Meredith E, Miranda K, Rao C, Capparelli M, Lemon DD, Phan D, Koch KA, Chapo JA, Hood DB, McKinsey TA.
FEBS Lett 584(3):631-7. Epub 2009 Dec 14.PMID: 20018189 2010
9CTTN, PRKD1, SSH1
Protein kinase D controls actin polymerization and cell motility through phosphorylation of cortactin.
Eiseler T, Hausser A, De Kimpe L, Van Lint J, Pfizenmaier K.
J Biol Chem 285(24):18672-83. Epub 2010 Apr 2.PMID: 20363754 2010
10PRKD1, PRKD2, SLC9A3R1, SLC9A3R2
The protein scaffold NHERF-1 controls the amplitude and duration of localized protein kinase D activity.
Kunkel MT, Garcia EL, Kajimoto T, Hall RA, Newton AC.
J Biol Chem 284(36):24653-61. Epub 2009 Jul 6.PMID: 19581308 2009
11AR, HSPB1, PRKD1
Heat shock protein 27 mediates repression of androgen receptor function by protein kinase D1 in prostate cancer cells.
Hassan S, Biswas MH, Zhang C, Du C, Balaji KC.
Oncogene 28(49):4386-96. Epub .PMID: 19767773 2009
12MYD88, PRKD1
Protein kinase D1 is essential for MyD88-dependent TLR signaling pathway.
Park JE, Kim YI, Yi AK.
J Immunol 182(10):6316-27.PMID: 19414785 2009
13PRKD1, SLC2A4
Identification of protein kinase D as a novel contraction-activated kinase linked to GLUT4-mediated glucose uptake, independent of AMPK.
Luiken JJ, Vertommen D, Coort SL, Habets DD, El Hasnaoui M, Pelsers MM, Viollet B, Bonen A, Hue L, Rider MH, Glatz JF.
Cell Signal 20(3):543-56. Epub 2007 Nov 26.PMID: 18164589 2008
14PRKD1
Protein kinase D1 stimulates MEF2 activity in skeletal muscle and enhances muscle performance.
Kim MS, Fielitz J, McAnally J, Shelton JM, Lemon DD, McKinsey TA, Richardson JA, Bassel-Duby R, Olson EN.
Mol Cell Biol 28(11):3600-9. Epub 2008 Mar 31.PMID: 18378694 2008
15PRKD1
PKD is recruited to sites of actin remodelling at the leading edge and negatively regulates cell migration.
Eiseler T, Schmid MA, Topbas F, Pfizenmaier K, Hausser A.
FEBS Lett 581(22):4279-87. Epub 2007 Aug 10. 2007
16PRKD1
Intracellular location and cell context-dependent function of protein kinase D.
Marklund U, Lightfoot K, Cantrell D.
Immunity 19(4):491-501. 2003
17PRKD1
Assignment of protein kinase C mu (PRKCM) to human chromosome band 14q11 with somatic cell hybrids and radiation hybrids.
Owczarek CM, Portbury KJ, Kola I, Hertzog PJ.
Cytogenet Cell Genet 89(3-4):240-1. No abstract available. 2000
18PRKD1
PKCu is a novel, atypical member of the protein kinase C family.
Johannes FJ, Prestle J, Eis S, Oberhagemann P, Pfizenmaier K.
J Biol Chem 269(8):6140-8. 1994