| 1 | APPL1, PRKCZ
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| APPL1 promotes glucose uptake in response to mechanical stretch via the PKCζ-non-muscle myosin IIa pathway in C2C12 myotubes.
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| Saito T, Okada S, Shimoda Y, Tagaya Y, Osaki A, Yamada E, Shibusawa R, Nakajima Y, Ozawa A, Satoh T, Mori M, Yamada M.
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| Cell Signal 28(11):1694-702. doi: 10.1016/j.cellsig.2016.07.010. Epub 2016 Jul 28.
2016
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| 2 | PHGDH, PRKCZ, PSAT1
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| Control of nutrient stress-induced metabolic reprogramming by PKCζ in tumorigenesis.
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| Ma L, Tao Y, Duran A, Llado V, Galvez A, Barger JF, Castilla EA, Chen J, Yajima T, Porollo A, Medvedovic M, Brill LM, Plas DR, Riedl SJ, Leitges M, Diaz-Meco MT, Richardson AD, Moscat J.
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| Cell 152(3):599-611. doi: 10.1016/j.cell.2012.12.028.
2013
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| 3 | EYA1, PRKCZ
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| Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium.
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| El-Hashash AH, Turcatel G, Varma S, Berika M, Al Alam D, Warburton D.
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| J Cell Sci 125(Pt 17):4036-48. doi: 10.1242/jcs.102848. Epub 2012 Jun 8.
2012
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| 4 | PRKCI, PRKCZ
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| Atypical protein kinase C (aPKCzeta and aPKClambda) is dispensable for mammalian hematopoietic stem cell activity and blood formation.
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| Sengupta A, Duran A, Ishikawa E, Florian MC, Dunn SK, Ficker AM, Leitges M, Geiger H, Diaz-Meco M, Moscat J, Cancelas JA.
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| Proc Natl Acad Sci U S A 108(24):9957-62. Epub 2011 Jun 8. Erratum in: Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12185.
2011
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| 5 | DLG4, NTRK2, PRKCZ
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| TrkB and protein kinase Mζ regulate synaptic localization of PSD-95 in developing cortex.
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| Yoshii A, Murata Y, Kim J, Zhang C, Shokat KM, Constantine-Paton M.
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| J Neurosci 31(33):11894-904.
2011
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| 6 | DEL1P36, GABRD, PRKCZ, SKI
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| Refinement of causative genes in monosomy 1p36 through clinical and molecular cytogenetic characterization of small interstitial deletions.
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| Rosenfeld JA, Crolla JA, Tomkins S, Bader P, Morrow B, Gorski J, Troxell R, Forster-Gibson C, Cilliers D, Hislop RG, Lamb A, Torchia B, Ballif BC, Shaffer LG.
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| Am J Med Genet A 152A(8):1951-9.PMID: 20635359 2010
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| 7 | PRKCI, PRKCZ
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| Protein kinase C isoforms zeta and iota mediate collagenase expression and cartilage destruction via STAT3- and ERK-dependent c-fos induction.
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| Litherland GJ, Elias MS, Hui W, Macdonald CD, Catterall JB, Barter MJ, Farren MJ, Jefferson M, Rowan AD.
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| J Biol Chem 285(29):22414-25. Epub 2010 May 12.
2010
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| 8 | MAPK7, NOS3, PRKCZ
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| PKCzeta decreases eNOS protein stability via inhibitory phosphorylation of ERK5.
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| Nigro P, Abe J, Woo CH, Satoh K, McClain C, O'Dell MR, Lee H, Lim JH, Li JD, Heo KS, Fujiwara K, Berk BC.
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| Blood 116(11):1971-9. doi: 10.1182/blood-2010-02-269134. Epub 2010 Jun 10.
2010
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| 9 | PRKCZ
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| An atypical protein kinase C (PKC zeta) plays a critical role in lipopolysaccharide-activated NF-kappa B in human peripheral blood monocytes and macrophages.
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| Huang X, Chen LY, Doerner AM, Pan WW, Smith L, Huang S, Papadimos TJ, Pan ZK.
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| J Immunol 182(9):5810-5.PMID: 19380829 2009
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| 10 | PRKCZ
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| Pivotal Advance: PKCzeta is required for migration of macrophages.
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| Guo H, Ma Y, Zhang B, Sun B, Niu R, Ying G, Zhang N.
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| J Leukoc Biol 85(6):911-8. Epub 2009 Feb 6.PMID: 19201988 2009
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| 11 | ARHGAP21, PRKCZ, PTK2
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| ARHGAP21 associates with FAK and PKCzeta and is redistributed after cardiac pressure overload.
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| Borges L, Bigarella CL, Baratti MO, Crosara-Alberto DP, Joazeiro PP, Franchini KG, Costa FF, Saad ST.
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| Biochem Biophys Res Commun 374(4):641-6. Epub 2008 Jul 26.
2008
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| 12 | CASP2, PRKCZ
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| PKC zeta controls DNA topoisomerase-dependent human caspase-2 pre-mRNA splicing.
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| Solier S, De Cian MC, Bettaieb A, Desoche L, Solary E, Corcos L.
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| FEBS Lett 582(2):372-8. Epub 2007 Dec 31. Erratum in: FEBS Lett. 2008 Feb 20;582(4):536. PMID: 18166155 2008
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| 13 | BAX, PRKCZ
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| Protein kinase Czeta abrogates the proapoptotic function of Bax through phosphorylation.
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| Xin M, Gao F, May WS, Flagg T, Deng X.
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| J Biol Chem 282(29):21268-77. Epub 2007 May 24.PMID: 1752516 2007
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| 14 | ECT2, PARD6A, PRKCZ
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| Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activity.
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| Liu XF, Ishida H, Raziuddin R, Miki T.
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| Mol Cell Biol 24(15):6665-75. 2004
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| 15 | PRKCZ,WWC1
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| KIBRA is a novel substrate for protein kinase Czeta.
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| Buther K, Plaas C, Barnekow A, Kremerskothen J.
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| Biochem Biophys Res Commun 317(3):703-7. 2004
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| 16 | EGF, PRKCZ
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| PKC-zeta is required in EGF protection of microtubules and intestinal barrier integrity against oxidant injury.
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| Banan A, Fields JZ, Talmage DA, Zhang L, Keshavarzian A.
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| Am J Physiol Gastrointest Liver Physiol 282(5):G794-808. 2002
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| 17 | PRKCZ
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| PKC-zeta mediates insulin effects on glucose transport in cultured preadipocyte-derived human adipocytes.
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| Bandyopadhyay G, Sajan MP, Kanoh Y, Standaert ML, Quon MJ, Lea-Currie R, Sen A, Farese RV.
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| J Clin Endocrinol Metab 87(2):716-23. 2002
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| 18 | PRKCA, PRKCB, PRKCZ
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| Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation.
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| Fontayne A, Dang PM, Gougerot-Pocidalo MA, El-Benna J.
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| Biochemistry 41(24):7743-50. 2002
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| 19 | PRKCZ, PAWR
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| Structural and functional characterization of the upstream regulatory region of the human gene encoding prostate apoptosis response factor-4.
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| Hsu SC, Kirschenbaum F, Miller J, Cordell B, McCarthy JV.
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| Gene 295(1):109-16. 2002
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| 20 | PRKCZ
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| Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway.
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| Leitges M, Sanz L, Martin P, Duran A, Braun U, Garcia JF, Camacho F, Diaz-Meco MT, Rennert PD, Moscat J.
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| Mol Cell 8(4):771-80. 2001
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| 21 | KCNAB2, PRKCZ, SLC39A1, SLC39A2
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| Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2.
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| Gong J, Xu J, Bezanilla M, van Huizen R, Derin R, Li M.
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| Science 285(5433):1565-9. 1999
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| 22 | PRKCA, PRKCZ
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| Activation and substrate specificity of the human protein kinase C alpha and zeta isoenzymes.
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| Kochs G, Hummel R, Meyer D, Hug H, Marme D, Sarre TF.
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| Eur J Biochem 216(2):597-606. 1993
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