| 1 | CLASP2, PARD3, PRKCI
|
| PAR3 and aPKC regulate Golgi organization through CLASP2 phosphorylation to generate cell polarity.
|
| Matsui T, Watanabe T, Matsuzawa K, Kakeno M, Okumura N, Sugiyama I, Itoh N, Kaibuchi K.
|
| Mol Biol Cell 26(4):751-61. doi: 10.1091/mbc.E14-09-1382. Epub 2014 Dec 17.
2015
|
| 2 | PARD3, PARD6A, PRKCI
|
| The PAR polarity complex and cerebellar granule neuron migration.
|
| Ramahi JS, Solecki DJ.
|
| Adv Exp Med Biol 800:113-31. doi: 10.1007/978-94-007-7687-6_7. Review.
2014
|
| 3 | CRB3, PARD6A, PRKCI, WDR83
|
| The WD40 protein Morg1 facilitates Par6-aPKC binding to Crb3 for apical identity in epithelial cells.
|
| Hayase J, Kamakura S, Iwakiri Y, Yamaguchi Y, Izaki T, Ito T, Sumimoto H.
|
| J Cell Biol 200(5):635-50. doi: 10.1083/jcb.201208150. Epub 2013 Feb 25. 2013
|
| 4 | PARD6A, PRKCI
|
| Atypical protein kinase C phosphorylates Par6 and facilitates transforming growth factor β-induced epithelial-to-mesenchymal transition.
|
| Gunaratne A, Thai BL, Di Guglielmo GM.
|
| Mol Cell Biol 33(5):874-86. doi: 10.1128/MCB.00837-12. Epub 2012 Dec 17.
2013
|
| 5 | PARD3, PARD6A, PRKCI, TIAM1
|
| Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration.
|
| Wang S, Watanabe T, Matsuzawa K, Katsumi A, Kakeno M, Matsui T, Ye F, Sato K, Murase K, Sugiyama I, Kimura K, Mizoguchi A, Ginsberg MH, Collard JG, Kaibuchi K.
|
| J Cell Biol 199(2):331-45. doi: 10.1083/jcb.201202041.
2012
|
| 6 | PARD6B, PRKCI
|
| Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis.
|
| Durgan J, Kaji N, Jin D, Hall A.
|
| J Biol Chem 286(14):12461-74. Epub 2011 Feb 7.
2011
|
| 7 | NUMB, PRKCI
|
| Numb controls E-cadherin endocytosis through p120 catenin with aPKC.
|
| Sato K, Watanabe T, Wang S, Kakeno M, Matsuzawa K, Matsui T, Yokoi K, Murase K, Sugiyama I, Ozawa M, Kaibuchi K.
|
| Mol Biol Cell 22(17):3103-19. Epub 2011 Jul 20.
2011
|
| 8 | CDC42, PRKCI
|
| Cdc42 controls vascular network assembly through protein kinase Cι during embryonic vasculogenesis.
|
| Qi Y, Liu J, Wu X, Brakebusch C, Leitges M, Han Y, Corbett SA, Lowry SF, Graham AM, Li S.
|
| Arterioscler Thromb Vasc Biol 31(8):1861-70. Epub 2011 Jun 9.
2011
|
| 9 | PRKCI, PRKCZ
|
| Atypical protein kinase C (aPKCzeta and aPKClambda) is dispensable for mammalian hematopoietic stem cell activity and blood formation.
|
| Sengupta A, Duran A, Ishikawa E, Florian MC, Dunn SK, Ficker AM, Leitges M, Geiger H, Diaz-Meco M, Moscat J, Cancelas JA.
|
| Proc Natl Acad Sci U S A 108(24):9957-62. Epub 2011 Jun 8. Erratum in: Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12185.
2011
|
| 10 | PRKCI, WWC1
|
| KIBRA suppresses apical exocytosis through inhibition of aPKC kinase activity in epithelial cells.
|
| Yoshihama Y, Sasaki K, Horikoshi Y, Suzuki A, Ohtsuka T, Hakuno F, Takahashi S, Ohno S, Chida K.
|
| Curr Biol 21(8):705-11. Epub 2011 Apr 14.
2011
|
| 11 | FRMD6, PARD3, PRKCI, ROCK1
|
| Willin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylation.
|
| Ishiuchi T, Takeichi M.
|
| Nat Cell Biol 13(7):860-6. doi: 10.1038/ncb2274.
2011
|
| 12 | PRKCI
|
| Atypical protein kinase C regulates primary dendrite specification of cerebellar Purkinje cells by localizing Golgi apparatus.
|
| Tanabe K, Kani S, Shimizu T, Bae YK, Abe T, Hibi M.
|
| J Neurosci 30(50):16983-92.
2010
|
| 13 | PRKCI
|
| The identification of protein kinase C iota as a regulator of the Mammalian heat shock response using functional genomic screens.
|
| Boellmann F, Thomas RS.
|
| PLoS One 5(7):e11850.
2010
|
| 14 | PRKCI, PRKCZ
|
| Protein kinase C isoforms zeta and iota mediate collagenase expression and cartilage destruction via STAT3- and ERK-dependent c-fos induction.
|
| Litherland GJ, Elias MS, Hui W, Macdonald CD, Catterall JB, Barter MJ, Farren MJ, Jefferson M, Rowan AD.
|
| J Biol Chem 285(29):22414-25. Epub 2010 May 12.
2010
|
| 15 | ECT2, PARD6A, PRKCI
|
| Ect2 links the PKCiota-Par6alpha complex to Rac1 activation and cellular transformation.
|
| Justilien V, Fields AP.
|
| Oncogene 28(41):3597-607. Epub 2009 Jul 20.PMID: 19617897 2009
|
| 16 | PRKCI, PRKCQ
|
| PKCtheta cooperates with atypical PKCzeta and PKCiota in NF-kappaB transactivation of T lymphocytes.
|
| Gruber T, Fresser F, Jenny M, Uberall F, Leitges M, Baier G.
|
| Mol Immunol 45(1):117-26. Epub 2007 Jun 22. 2008
|
| 17 | PRKCI
|
| Amplification of PRKCI, located in 3q26, is associated with lymph node metastasis in esophageal squamous cell carcinoma.
|
| Yang YL, Chu JY, Luo ML, Wu YP, Zhang Y, Feng YB, Shi ZZ, Xu X, Han YL, Cai Y, Dong JT, Zhan QM, Wu M, Wang MR.
|
| Genes Chromosomes Cancer 47(2):127-36. 2008
|
| 18 | CDK7, PRKCI
|
| Cyclin-dependent kinase activating kinase/Cdk7 co-localizes with PKC-iota in human glioma cells.
|
| Bicaku E, Patel R, Acevedo-Duncan M.
|
| Tissue Cell 37(1):53-8. Epub 2005 Jan 25.
2005
|
| 19 | PRKCI
|
| Atypical protein kinase C plays a critical role in protein transport from pre-Golgi intermediates.
|
| Tisdale EJ, Wang J, Silver RB, Artalejo CR.
|
| J Biol Chem 278(39):38015-21. Epub 2003 Jul 17. 2003
|
| 20 | PRKCI, PRKCIP
|
| The assignment of PRKCI to bovine chromosome 1q34-->q36 by FISH suggests a new assignment to human chromosome 3.
|
| De Donato M, Gallagher DS Jr, Davis SK, Stelly DM, Taylor JF.
|
| Cytogenet Cell Genet 95(1-2):79-81. 2001
|
| 21 | BTK, PRKCI
|
| Human protein kinase C iota gene (PRKCI) is closely linked to the BTK gene in Xq21.3.
|
| Mazzarella R, et al.
|
| Genomics 26 : 629-631. 1995
|