Citations for
1IVL, PRKCD, PRKCD, WDR77
MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation and this Is Reversed by PKCδ/p38δ Signaling.
Saha K, Adhikary G, Eckert RL.
J Invest Dermatol 136(1):214-24. doi: 10.1038/JID.2015.400. 2016
2MARCKS, PRKCD
In Vitro Neutrophil Migration Requires Protein Kinase C-Delta (δ-PKC)-Mediated Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Phosphorylation.
Sheats MK, Sung EJ, Adler KB, Jones SL.
Inflammation 38(3):1126-41. doi: 10.1007/s10753-014-0078-9. 2015
3BTK, MAL, PRKCD
Structural evaluation of BTK and PKCδ mediated phosphorylation of MAL at positions Tyr86 and Tyr106.
Paracha RZ, Ali A, Ahmad J, Hussain R, Niazi U, Muhammad SA.
Comput Biol Chem 51:22-35. doi: 10.1016/j.compbiolchem.2014.04.001. Epub 2014 Apr 20. 2014
4CVID9, PRKCD
B-cell deficiency and severe autoimmunity caused by deficiency of protein kinase C δ.
Salzer E, Santos-Valente E, Klaver S, Ban SA, Emminger W, Prengemann NK, Garncarz W, Müllauer L, Kain R, Boztug H, Heitger A, Arbeiter K, Eitelberger F, Seidel MG, Holter W, Pollak A, Pickl WF, Förster-Waldl E, Boztug K.
Blood 121(16):3112-6. doi: 10.1182/blood-2012-10-460741. Epub 2013 Jan 14. 2013
5CTSK, MARCKS, PRKCD
Protein kinase C-delta deficiency perturbs bone homeostasis by selective uncoupling of cathepsin K secretion and ruffled border formation in osteoclasts.
Cremasco V, Decker CE, Stumpo D, Blackshear PJ, Nakayama KI, Nakayama K, Lupu TS, Graham DB, Novack DV, Faccio R.
J Bone Miner Res 27(12):2452-63. doi: 10.1002/jbmr.1701. 2012
6PRKCD, TRO
Trophinin-mediated cell adhesion induces apoptosis of human endometrial epithelial cells through PKC-δ.
Tamura N, Sugihara K, Akama TO, Fukuda MN.
Cell Cycle 10(1):135-43. Epub 2011 Jan 1. 2011
7CLDN1, PRKCD
Claudin-1 acts through c-Abl-protein kinase Cdelta (PKCdelta) signaling and has a causal role in the acquisition of invasive capacity in human liver cells.
Yoon CH, Kim MJ, Park MJ, Park IC, Hwang SG, An S, Choi YH, Yoon G, Lee SJ.
J Biol Chem 285(1):226-33. Epub 2009 Nov 6.PMID: 19897486 2010
8PRKCD
Protein kinase C-delta is involved in the inflammatory effect of IL-6 in mouse adipose cells.
Wallerstedt E, Smith U, Andersson CX.
Diabetologia 53(5):946-54. Epub 2010 Feb 12.PMID: 20151299 2010
9PRKCD, PRKCH
Protein kinase C delta and eta differently regulate the expression of loricrin and Jun family proteins in human keratinocytes.
Kamioka N, Akahane T, Kohno Y, Kuroki T, Iijima M, Honma I, Ohba M.
Biochem Biophys Res Commun 394(1):106-11. Epub 2010 Feb 23. 2010
10PRKCA, PRKCD, PRKCE
PKC{delta} is activated in a dietary model of steatohepatitis and regulates endoplasmic reticulum stress and cell death.
Greene MW, Burrington CM, Ruhoff MS, Johnson AK, Chongkrairatanakul T, Kangwanpornsiri A.
J Biol Chem 285(53):42115-29. Epub 2010 Oct 22. 2010
11PRKCD
Caspase-mediated protein kinase C-delta cleavage is necessary for apoptosis of vascular smooth muscle cells.
Kato K, Yamanouchi D, Esbona K, Kamiya K, Zhang F, Kent KC, Liu B.
Am J Physiol Heart Circ Physiol 297(6):H2253-61. Epub 2009 Oct 16.PMID: 19837952 2009
12PRKCD, TERT
Protein kinase C delta plays a key role in cellular senescence programs of human normal diploid cells.
Katakura Y, Udono M, Katsuki K, Nishide H, Tabira Y, Ikei T, Yamashita M, Fujiki T, Shirahata S.
J Biochem 146(1):87-93. Epub 2009 Mar 11.PMID: 19279193 2009
13PRKCD
Protein kinase C[delta] differentially regulates platelet functional responses.
Chari R, Getz T, Nagy B Jr, Bhavaraju K, Mao Y, Bynagari YS, Murugappan S, Nakayama K, Kunapuli SP.
Arterioscler Thromb Vasc Biol 29(5):699-705. Epub 2009 Feb 12.PMID: 19213940 2009
14PRKCD, PRKCE
Diverse roles for protein kinase C delta and protein kinase C epsilon in the generation of high-fat-diet-induced glucose intolerance in mice: regulation of lipogenesis by protein kinase C delta.
Frangioudakis G, Burchfield JG, Narasimhan S, Cooney GJ, Leitges M, Biden TJ, Schmitz-Peiffer C.
Diabetologia 52(12):2616-20. Epub 2009 Oct 7. 2009
15DYRK2, ABL1, PRKCD, PRKDC
Nuclear trafficking of pro-apoptotic kinases in response to DNA damage.
Yoshida K.
Trends Mol Med 14(7):305-13. Epub 2008 Jun 6. 2008
16PRKCD
Protein kinase C delta localizes to secretory lysosomes in CD8+ CTL and directly mediates TCR signals leading to granule exocytosis-mediated cytotoxicity.
Ma JS, Haydar TF, Radoja S.
J Immunol 181(7):4716-22.PMID: 18802074 2008
17PRKCD
Sustained pharmacological inhibition of deltaPKC protects against hypertensive encephalopathy through prevention of blood-brain barrier breakdown in rats.
Qi X, Inagaki K, Sobel RA, Mochly-Rosen D.
J Clin Invest 118(1):173-82.PMID: 18097471 2008
18IFIT3, IFNA1, MAPK8, PRKCD
Sequential activation of protein kinase C delta and JNK is required for interferon-alpha-induced expression of IFIT4.
Huang X, Yang N, Ou X, Li D, Wang Z, Xie Q, Chen Y, Lin H, Yin G, Wen F.
Cell Signal 20(1):112-9. 2008
19PRKCD,SOCS6
Increased SOCS6 stability with PMA requires its N-terminal region and the Erk pathway via Pkcdelta activation.
Hwang MN, Ha TH, Park J, Shim J, Lee H, Kim YN, Lee ES, Yoon S.
Biochem Biophys Res Commun 354(1):184-9. Epub 2006 Dec 29. 2007
20PRKCD
Activation of acid sphingomyelinase by protein kinase Cdelta-mediated phosphorylation.
Zeidan YH, Hannun YA.
J Biol Chem 282(15):11549-61. Epub 2007 Feb 15. 2007
21PRKCD, SDC2
Dual involvement of protein kinase C delta in apoptosis induced by syndecan-2 in osteoblasts.
Orosco A, Fromigue O, Hay E, Marie PJ, Modrowski D.
J Cell Biochem 98(4):838-50. 2006
22PRKCD
Protein kinase PKC delta and c-Abl are required for mitochondrial apoptosis induction by genotoxic stress in the absence of p53, p73 and Fas receptor.
Lasfer M, Davenne L, Vadrot N, Alexia C, Sadji-Ouatas Z, Bringuier AF, Feldmann G, Pessayre D, Reyl-Desmars F.
FEBS Lett 580(11):2547-52. Epub 2006 Apr 12. 2006
23VHL, PRKCD
The von Hippel-Lindau tumour-suppressor protein interaction with protein kinase Cdelta.
Iturrioz X, Durgan J, Calleja V, Larijani B, Okuda H, Whelan R, Parker PJ.
Biochem J 397(1):109-20. 2006
24PRKCD
Genomic structure and promoter analysis of PKC-delta.
Suh KS, Tatunchak TT, Crutchley JM, Edwards LE, Marin KG, Yuspa SH.
Genomics 82(1):57-67. 2003
25PLSCR3, PRKCD
Phospholipid scramblase 3 is the mitochondrial target of protein kinase C delta-induced apoptosis.
Liu J, Chen J, Dai Q, Lee RM.
Cancer Res 63(6):1153-6.PMID: 12649167 2003
26PDP2, PRKCD
Activation and mitochondrial translocation of protein kinase Cdelta are necessary for insulin stimulation of pyruvate dehydrogenase complex activity in muscle and liver cells.
Caruso M, Maitan MA, Bifulco G, Miele C, Vigliotta G, Oriente F, Formisano P, Beguinot F.
J Biol Chem 276(48):45088-97. Epub 2001 Sep 27. 2001
27PRKCD
A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
Izumi Y, Hirata M, Hasuwa H, Iwamoto R, Umata T, Miyado K, Tamai Y, Kurisaki T, Sehara-Fujisawa A, Ohno S, Mekada E.
EMBO J 17 : 7260-7272. 1998
28PRKCD
Assignment of the protein kinase C delta polypeptide gene (PRKCD) to human chromosome 3 and mouse chromosome 14.
Huppi K, et al.
Genomics 19 : 161-162. 1994