Citations for
1PRKCB, USP9X, ZAP70
Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity.
Naik E, Dixit VM.
J Immunol 196(8):3438-51. doi: 10.4049/jimmunol.1403165. Epub 2016 Mar 2. 2016
2PRKCB, SYK
Tyrosine phosphorylation on spleen tyrosine kinase (Syk) is differentially regulated in human and murine platelets by protein kinase C isoforms.
Buitrago L, Bhavanasi D, Dangelmaier C, Manne BK, Badolia R, Borgognone A, Tsygankov AY, McKenzie SE, Kunapuli SP.
J Biol Chem 288(40):29160-9. doi: 10.1074/jbc.M113.464107. Epub 2013 Aug 19. 2013
3PRKCA, PRKCB
Unravelling the different functions of protein kinase C isoforms in platelets.
Heemskerk JW, Harper MT, Cosemans JM, Poole AW.
FEBS Lett 585(12):1711-6. Epub 2011 May 13. 2011
4PRKCB
Crystal structure and allosteric activation of protein kinase C βII.
Leonard TA, Różycki B, Saidi LF, Hummer G, Hurley JH.
Cell 144(1):55-66. 2011
5PRKCB
Follow-up study identifies two novel susceptibility loci PRKCB and 8p11.21 for systemic lupus erythematosus.
Sheng YJ, Gao JP, Li J, Han JW, Xu Q, Hu WL, Pan TM, Cheng YL, Yu ZY, Ni C, Yao S, He CF, Liu YS, Li Y, Ge HM, Xiao FL, Sun LD, Yang S, Zhang XJ.
Rheumatology (Oxford) 50(4):682-8. Epub 2010 Dec 6. 2011
6PRKCB
PKCβII inhibition attenuates myocardial infarction induced heart failure and is associated with a reduction of fibrosis and pro-inflammatory responses.
Palaniyandi SS, Ferreira JC, Brum PC, Mochly-Rosen D.
J Cell Mol Med 15(8):1769-77. doi: 10.1111/j.1582-4934.2010.01174.x. 2011
7EDN1, PRKCA, PRKCB
Novel regulation of endothelin-1 promoter activity by protein kinase C.
Stricklett PK, Strait KA, Kohan DE.
Cell Biochem Biophys 61(3):643-50. doi: 10.1007/s12013-011-9250-0. 2011
8PDLIM5, PRKCB
LIM domains regulate protein kinase C activity: a novel molecular function.
Maturana AD, Nakagawa N, Yoshimoto N, Tatematsu K, Hoshijima M, Tanizawa K, Kuroda S.
Cell Signal 23(5):928-34. doi: 10.1016/j.cellsig.2011.01.021. Epub 2011 Jan 23. 2011
9PRKCB
Genetic variants of the protein kinase C-beta 1 gene and development of end-stage renal disease in patients with type 2 diabetes.
Ma RC, Tam CH, Wang Y, Luk AO, Hu C, Yang X, Lam V, Chan AW, Ho JS, Chow CC, Tong PC, Jia W, Ng MC, So WY, Chan JC.
JAMA 304(8):881-9. 2010
10ELAVL1, PRKCB
The PKCbeta/HuR/VEGF pathway in diabetic retinopathy.
Amadio M, Bucolo C, Leggio GM, Drago F, Govoni S, Pascale A.
Biochem Pharmacol 80(8):1230-7. Epub 2010 Jul 1. 2010
11PRKCB
Protein kinase C regulates rod photoreceptor differentiation through modulation of STAT3 signaling.
Pinzon-Guzman C, Shaomin Zhang S, Barnstable CJ.
Adv Exp Med Biol 664:21-8. 2010
12PRKCB
Vascular endothelial growth factor stimulates protein kinase CbetaII expression in chronic lymphocytic leukemia cells.
Abrams ST, Brown BR, Zuzel M, Slupsky JR.
Blood 115(22):4447-54. Epub 2010 Feb 17. 2010
13EFHD2, PRKCB, PRKCH
Swiprosin-1 is expressed in mast cells and up-regulated through the protein kinase C beta I/eta pathway.
Thylur RP, Kim YD, Kwon MS, Oh HM, Kwon HK, Kim SH, Im SH, Chun JS, Park ZY, Jun CD.
J Cell Biochem 108(3):705-15.PMID: 19693767 2009
14PRKCB
Role of protein kinase C beta2 activation in TNF-alpha-induced human vascular endothelial cell apoptosis.
Wang F, Liu HM, Irwin MG, Xia ZY, Huang Z, Ouyang J, Xia Z.
Can J Physiol Pharmacol 87(3):221-9. 2009
15PRKCB, RBCK1
RBCK1, a protein kinase CbetaI (PKCbetaI)-interacting protein, regulates PKCbeta-dependent function.
Vallentin A, Mochly-Rosen D.
J Biol Chem 282(3):1650-7. Epub 2006 Nov 22. 2007
16PRKCB
Chondrocyte cell death mediated by reactive oxygen species-dependent activation of PKC-betaI.
DelCarlo M, Loeser RF.
Am J Physiol Cell Physiol 290(3):C802-11. Epub 2005 Oct 19. 2006
17PRKCB
Protein kinase C betaII plays an essential role in dendritic cell differentiation and autoregulates its own expression.
Cejas PJ, Carlson LM, Zhang J, Padmanabhan S, Kolonias D, Lindner I, Haley S, Boise LH, Lee KP.
J Biol Chem 280(31):28412-23. Epub 2005 May 25. 2005
18PRKCB
Haplotypes in the gene encoding protein kinase c-beta (PRKCB1) on chromosome 16 are associated with autism.
Philippi A, Roschmann E, Tores F, Lindenbaum P, Benajou A, Germain-Leclerc L, Marcaillou C, Fontaine K, Vanpeene M, Roy S, Maillard S, Decaulne V, Saraiva JP, Brooks P, Rousseau F, Hager J.
Mol Psychiatry 10(10):950-60. 2005
19PRKCB
Centrosomal anchoring of protein kinase C betaII by pericentrin controls microtubule organization, spindle function, and cytokinesis.
Chen D, Purohit A, Halilovic E, Doxsey SJ, Newton AC.
J Biol Chem 279(6):4829-39. Epub 2003 Nov 1. 2004
20PRKCB
Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway.
Zhang J, Anastasiadis PZ, Liu Y, Thompson EA, Fields AP.
J Biol Chem 279(21):22118-23. Epub 2004 Mar 22. 2004
21PRKCB
Isoenzyme-specific translocation of protein kinase C (PKC)betaII and not PKCbetaI to a juxtanuclear subset of recycling endosomes: involvement of phospholipase D.
Becker KP, Hannun YA.
J Biol Chem 279(27):28251-6. Epub 2004 Apr 5. 2004
22PRKCB
Protein kinase CbetaII regulates its own expression in rat intestinal epithelial cells and the colonic epithelium in vivo.
Liu Y, Su W, Thompson EA, Leitges M, Murray NR, Fields AP.
J Biol Chem 279(44):45556-63. Epub 2004 Aug 20. 2004
23PRKCB
Protein kinase C beta is required for human monocyte chemotaxis to MCP-1.
Carnevale KA, Cathcart MK.
J Biol Chem 278(28):25317-22. Epub 2003 Apr 30. 2003
24PRKCB
Identification of a common risk haplotype for diabetic nephropathy at the protein kinase C-beta1 (PRKCB1) gene locus.
Araki S, Ng DP, Krolewski B, Wyrwicz L, Rogus JJ, Canani L, Makita Y, Haneda M, Warram JH, Krolewski AS.
J Am Soc Nephrol 14(8):2015-24. 2003
25PRKCB
cPKC-dependent sequestration of membrane-recycling components in a subset of recycling endosomes.
Becker KP, Hannun YA.
J Biol Chem 278(52):52747-54. Epub 2003 Oct 3. 2003
26TYR, TYRP1, PRKCB
Protein kinase C-beta-mediated complex formation between tyrosinase and TRP-1.
Wu H, Park HY.
Biochem Biophys Res Commun 311(4):948-53. 2003
27PRKCA, PRKCB, PRKCZ
Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation.
Fontayne A, Dang PM, Gougerot-Pocidalo MA, El-Benna J.
Biochemistry 41(24):7743-50. 2002
28EGF, PRKCB
The beta 1 isoform of protein kinase C mediates the protective effects of epidermal growth factor on the dynamic assembly of F-actin cytoskeleton and normalization of calcium homeostasis in human colonic cells.
Banan A, Fields JZ, Farhadi A, Talmage DA, Zhang L, Keshavarzian A.
J Pharmacol Exp Ther 301(3):852-66. 2002
29PRKCB
Regulation of receptor-mediated protein kinase C membrane trafficking by autophosphorylation.
Feng X, Becker KP, Stribling SD, Peters KG, Hannun YA.
J Biol Chem 275(22):17024-34. 2000
30NELL1, PRKCB
Involvement of epidermal growth factor-like domain of NELL proteins in the novel protein-protein interaction with protein kinase C.
Kuroda S, Tanizawa K.
Biochem Biophys Res Commun 265(3):752-7. 1999
31PRKCB
Elucidation of the exon-intron structure and size of the human protein kinase C beta gene (PRKCB).
Greenham J, et al.
Hum Genet 103(4):483-7 1998
32PRKCA, PRKCB, PRKCG
The complete primary structure of protein kinase C : the major phobol ester receptor.
Parker PJ, et al.
Science 233 : 853-859. 1986
33PRKCA, PRKCB, PRKCG
Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways.
Coussens L, et al.
Science 233 : 859-866. 1986