| 1 | PRKCB, USP9X, ZAP70
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| Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity.
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| Naik E, Dixit VM.
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| J Immunol 196(8):3438-51. doi: 10.4049/jimmunol.1403165. Epub 2016 Mar 2.
2016
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| 2 | PRKCB, SYK
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| Tyrosine phosphorylation on spleen tyrosine kinase (Syk) is differentially regulated in human and murine platelets by protein kinase C isoforms.
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| Buitrago L, Bhavanasi D, Dangelmaier C, Manne BK, Badolia R, Borgognone A, Tsygankov AY, McKenzie SE, Kunapuli SP.
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| J Biol Chem 288(40):29160-9. doi: 10.1074/jbc.M113.464107. Epub 2013 Aug 19.
2013
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| 3 | PRKCA, PRKCB
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| Unravelling the different functions of protein kinase C isoforms in platelets.
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| Heemskerk JW, Harper MT, Cosemans JM, Poole AW.
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| FEBS Lett 585(12):1711-6. Epub 2011 May 13.
2011
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| 4 | PRKCB
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| Crystal structure and allosteric activation of protein kinase C βII.
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| Leonard TA, Różycki B, Saidi LF, Hummer G, Hurley JH.
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| Cell 144(1):55-66.
2011
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| 5 | PRKCB
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| Follow-up study identifies two novel susceptibility loci PRKCB and 8p11.21 for systemic lupus erythematosus.
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| Sheng YJ, Gao JP, Li J, Han JW, Xu Q, Hu WL, Pan TM, Cheng YL, Yu ZY, Ni C, Yao S, He CF, Liu YS, Li Y, Ge HM, Xiao FL, Sun LD, Yang S, Zhang XJ.
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| Rheumatology (Oxford) 50(4):682-8. Epub 2010 Dec 6.
2011
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| 6 | PRKCB
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| PKCβII inhibition attenuates myocardial infarction induced heart failure and is associated with a reduction of fibrosis and pro-inflammatory responses.
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| Palaniyandi SS, Ferreira JC, Brum PC, Mochly-Rosen D.
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| J Cell Mol Med 15(8):1769-77. doi: 10.1111/j.1582-4934.2010.01174.x.
2011
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| 7 | EDN1, PRKCA, PRKCB
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| Novel regulation of endothelin-1 promoter activity by protein kinase C.
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| Stricklett PK, Strait KA, Kohan DE.
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| Cell Biochem Biophys 61(3):643-50. doi: 10.1007/s12013-011-9250-0.
2011
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| 8 | PDLIM5, PRKCB
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| LIM domains regulate protein kinase C activity: a novel molecular function.
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| Maturana AD, Nakagawa N, Yoshimoto N, Tatematsu K, Hoshijima M, Tanizawa K, Kuroda S.
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| Cell Signal 23(5):928-34. doi: 10.1016/j.cellsig.2011.01.021. Epub 2011 Jan 23.
2011
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| 9 | PRKCB
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| Genetic variants of the protein kinase C-beta 1 gene and development of end-stage renal disease in patients with type 2 diabetes.
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| Ma RC, Tam CH, Wang Y, Luk AO, Hu C, Yang X, Lam V, Chan AW, Ho JS, Chow CC, Tong PC, Jia W, Ng MC, So WY, Chan JC.
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| JAMA 304(8):881-9.
2010
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| 10 | ELAVL1, PRKCB
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| The PKCbeta/HuR/VEGF pathway in diabetic retinopathy.
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| Amadio M, Bucolo C, Leggio GM, Drago F, Govoni S, Pascale A.
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| Biochem Pharmacol 80(8):1230-7. Epub 2010 Jul 1.
2010
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| 11 | PRKCB
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| Protein kinase C regulates rod photoreceptor differentiation through modulation of STAT3 signaling.
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| Pinzon-Guzman C, Shaomin Zhang S, Barnstable CJ.
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| Adv Exp Med Biol 664:21-8.
2010
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| 12 | PRKCB
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| Vascular endothelial growth factor stimulates protein kinase CbetaII expression in chronic lymphocytic leukemia cells.
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| Abrams ST, Brown BR, Zuzel M, Slupsky JR.
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| Blood 115(22):4447-54. Epub 2010 Feb 17.
2010
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| 13 | EFHD2, PRKCB, PRKCH
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| Swiprosin-1 is expressed in mast cells and up-regulated through the protein kinase C beta I/eta pathway.
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| Thylur RP, Kim YD, Kwon MS, Oh HM, Kwon HK, Kim SH, Im SH, Chun JS, Park ZY, Jun CD.
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| J Cell Biochem 108(3):705-15.PMID: 19693767 2009
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| 14 | PRKCB
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| Role of protein kinase C beta2 activation in TNF-alpha-induced human vascular endothelial cell apoptosis.
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| Wang F, Liu HM, Irwin MG, Xia ZY, Huang Z, Ouyang J, Xia Z.
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| Can J Physiol Pharmacol 87(3):221-9.
2009
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| 15 | PRKCB, RBCK1
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| RBCK1, a protein kinase CbetaI (PKCbetaI)-interacting protein, regulates PKCbeta-dependent function.
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| Vallentin A, Mochly-Rosen D.
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| J Biol Chem 282(3):1650-7. Epub 2006 Nov 22. 2007
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| 16 | PRKCB
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| Chondrocyte cell death mediated by reactive oxygen species-dependent activation of PKC-betaI.
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| DelCarlo M, Loeser RF.
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| Am J Physiol Cell Physiol 290(3):C802-11. Epub 2005 Oct 19. 2006
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| 17 | PRKCB
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| Protein kinase C betaII plays an essential role in dendritic cell differentiation and autoregulates its own expression.
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| Cejas PJ, Carlson LM, Zhang J, Padmanabhan S, Kolonias D, Lindner I, Haley S, Boise LH, Lee KP.
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| J Biol Chem 280(31):28412-23. Epub 2005 May 25. 2005
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| 18 | PRKCB
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| Haplotypes in the gene encoding protein kinase c-beta (PRKCB1) on chromosome 16 are associated with autism.
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| Philippi A, Roschmann E, Tores F, Lindenbaum P, Benajou A, Germain-Leclerc L, Marcaillou C, Fontaine K, Vanpeene M, Roy S, Maillard S, Decaulne V, Saraiva JP, Brooks P, Rousseau F, Hager J.
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| Mol Psychiatry 10(10):950-60. 2005
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| 19 | PRKCB
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| Centrosomal anchoring of protein kinase C betaII by pericentrin controls microtubule organization, spindle function, and cytokinesis.
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| Chen D, Purohit A, Halilovic E, Doxsey SJ, Newton AC.
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| J Biol Chem 279(6):4829-39. Epub 2003 Nov 1. 2004
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| 20 | PRKCB
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| Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway.
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| Zhang J, Anastasiadis PZ, Liu Y, Thompson EA, Fields AP.
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| J Biol Chem 279(21):22118-23. Epub 2004 Mar 22. 2004
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| 21 | PRKCB
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| Isoenzyme-specific translocation of protein kinase C (PKC)betaII and not PKCbetaI to a juxtanuclear subset of recycling endosomes: involvement of phospholipase D.
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| Becker KP, Hannun YA.
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| J Biol Chem 279(27):28251-6. Epub 2004 Apr 5. 2004
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| 22 | PRKCB
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| Protein kinase CbetaII regulates its own expression in rat intestinal epithelial cells and the colonic epithelium in vivo.
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| Liu Y, Su W, Thompson EA, Leitges M, Murray NR, Fields AP.
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| J Biol Chem 279(44):45556-63. Epub 2004 Aug 20. 2004
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| 23 | PRKCB
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| Protein kinase C beta is required for human monocyte chemotaxis to MCP-1.
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| Carnevale KA, Cathcart MK.
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| J Biol Chem 278(28):25317-22. Epub 2003 Apr 30. 2003
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| 24 | PRKCB
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| Identification of a common risk haplotype for diabetic nephropathy at the protein kinase C-beta1 (PRKCB1) gene locus.
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| Araki S, Ng DP, Krolewski B, Wyrwicz L, Rogus JJ, Canani L, Makita Y, Haneda M, Warram JH, Krolewski AS.
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| J Am Soc Nephrol 14(8):2015-24. 2003
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| 25 | PRKCB
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| cPKC-dependent sequestration of membrane-recycling components in a subset of recycling endosomes.
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| Becker KP, Hannun YA.
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| J Biol Chem 278(52):52747-54. Epub 2003 Oct 3. 2003
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| 26 | TYR, TYRP1, PRKCB
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| Protein kinase C-beta-mediated complex formation between tyrosinase and TRP-1.
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| Wu H, Park HY.
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| Biochem Biophys Res Commun 311(4):948-53. 2003
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| 27 | PRKCA, PRKCB, PRKCZ
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| Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation.
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| Fontayne A, Dang PM, Gougerot-Pocidalo MA, El-Benna J.
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| Biochemistry 41(24):7743-50. 2002
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| 28 | EGF, PRKCB
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| The beta 1 isoform of protein kinase C mediates the protective effects of epidermal growth factor on the dynamic assembly of F-actin cytoskeleton and normalization of calcium homeostasis in human colonic cells.
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| Banan A, Fields JZ, Farhadi A, Talmage DA, Zhang L, Keshavarzian A.
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| J Pharmacol Exp Ther 301(3):852-66. 2002
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| 29 | PRKCB
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| Regulation of receptor-mediated protein kinase C membrane trafficking by autophosphorylation.
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| Feng X, Becker KP, Stribling SD, Peters KG, Hannun YA.
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| J Biol Chem 275(22):17024-34. 2000
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| 30 | NELL1, PRKCB
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| Involvement of epidermal growth factor-like domain of NELL proteins in the novel protein-protein interaction with protein kinase C.
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| Kuroda S, Tanizawa K.
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| Biochem Biophys Res Commun 265(3):752-7. 1999
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| 31 | PRKCB
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| Elucidation of the exon-intron structure and size of the human protein kinase C beta gene (PRKCB).
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| Greenham J, et al.
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| Hum Genet 103(4):483-7 1998
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| 32 | PRKCA, PRKCB, PRKCG
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| The complete primary structure of protein kinase C : the major phobol ester receptor.
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| Parker PJ, et al.
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| Science 233 : 853-859. 1986
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| 33 | PRKCA, PRKCB, PRKCG
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| Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways.
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| Coussens L, et al.
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| Science 233 : 859-866. 1986
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