| 1 | PRDM16, REST, SRCAP
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| The chromatin remodeler SRCAP promotes self-renewal of intestinal stem cells.
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| Ye B, Yang L, Qian G, Liu B, Zhu X, Zhu P, Ma J, Xie W, Li H, Lu T, Wang Y, Wang S, Du Y, Wang Z, Jiang J, Li J, Fan D, Meng S, Wu J, Tian Y, Fan Z.
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| EMBO J. Jul 1;39(13):e103786. doi: 10.15252/embj.2019103786. Epub 2020 May 25 2020
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| 2 | MECOM, PRDM16
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| Prdm3 and Prdm16 cooperatively maintain hematopoiesis and clonogenic potential.
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| McGlynn KA, Sun R, Vonica A, Rudzinskas S, Zhang Y, Perkins AS.
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| Exp Hematol. May;85:20-32.e3. doi: 10.1016/j.exphem.2020.04.010. Epub 2020 May 11. 2020
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| 3 | MED1, PRDM16, UCP1
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| PRDM16 enhances nuclear receptor-dependent transcription of the brown fat-specific Ucp1 gene through interactions with Mediator subunit MED1.
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| Iida S, Chen W, Nakadai T, Ohkuma Y, Roeder RG.
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| Genes Dev 29(3):308-21. doi: 10.1101/gad.252809.114.
2015
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| 4 | MED1, PRDM16
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| PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program.
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| Harms MJ, Lim HW, Ho Y, Shapira SN, Ishibashi J, Rajakumari S, Steger DJ, Lazar MA, Won KJ, Seale P.
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| Genes Dev 29(3):298-307. doi: 10.1101/gad.252734.114.
2015
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| 5 | PRDM16
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| Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice.
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| Harms MJ, Ishibashi J, Wang W, Lim HW, Goyama S, Sato T, Kurokawa M, Won KJ, Seale P.
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| Cell Metab 19(4):593-604. doi: 10.1016/j.cmet.2014.03.007.
2014
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| 6 | LVNC8, PRDM16
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| Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy.
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| Arndt AK, Schafer S, Drenckhahn JD, Sabeh MK, Plovie ER, Caliebe A, Klopocki E, Musso G, Werdich AA, Kalwa H, Heinig M, Padera RF, Wassilew K, Bluhm J, Harnack C, Martitz J, Barton PJ, Greutmann M, Berger F, Hubner N, Siebert R, Kramer HH, Cook SA, MacRae CA, Klaassen S.
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| Am J Hum Genet 93(1):67-77. doi: 10.1016/j.ajhg.2013.05.015. Epub 2013 Jun 13.
2013
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| 7 | EHMT1, PRDM16
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| EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex.
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| Ohno H, Shinoda K, Ohyama K, Sharp LZ, Kajimura S.
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| Nature 504(7478):163-7. doi: 10.1038/nature12652.
2013
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| 8 | IGF2, MYOD1, PRDM16
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| Double Myod and Igf2 inactivation promotes brown adipose tissue development by increasing Prdm16 expression.
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| Borensztein M, Viengchareun S, Montarras D, Journot L, Binart N, Lombès M, Dandolo L.
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| FASEB J 26(11):4584-91. doi: 10.1096/fj.12-208496. Epub 2012 Aug 2.
2012
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| 9 | MECOM, PRDM16, SUV39H1
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| Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.
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| Pinheiro I, Margueron R, Shukeir N, Eisold M, Fritzsch C, Richter FM, Mittler G, Genoud C, Goyama S, Kurokawa M, Son J, Reinberg D, Lachner M, Jenuwein T.
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| Cell 150(5):948-60. doi: 10.1016/j.cell.2012.06.048.
2012
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| 10 | IGF2, MYOD1, PRDM16, UCP1
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| Double Myod and Igf2 inactivation promotes brown adipose tissue development by increasing Prdm16 expression.
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| Borensztein M, Viengchareun S, Montarras D, Journot L, Binart N, Lombès M, Dandolo L.
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| FASEB J 26(11):4584-91. doi: 10.1096/fj.12-208496. Epub 2012 Aug 2.
2012
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| 11 | PRDM16
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| Prdm16 is a physiological regulator of hematopoietic stem cells.
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| Aguilo F, Avagyan S, Labar AS, Sevilla A, Lee DF, Kumar P, Lemischka IR, Zhou BY, Snoeck HW.
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| Blood lood. 2011 Feb 22. [Epub ahead of print]
2011
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| 12 | HGF, PRDM16
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| Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress.
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| Chuikov S, Levi BP, Smith ML, Morrison SJ.
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| Nat Cell Biol 12(10):999-1006. Epub 2010 Sep 12. 2010
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| 13 | PRDM16
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| Prdm16 is required for normal palatogenesis in mice.
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| Bjork BC, Turbe-Doan A, Prysak M, Herron BJ, Beier DR.
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| Hum Mol Genet 19(5):774-89. Epub 2009 Dec 11.
2010
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| 14 | PRDM16, SKI
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| SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells.
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| Takahata M, Inoue Y, Tsuda H, Imoto I, Koinuma D, Hayashi M, Ichikura T, Yamori T, Nagasaki K, Yoshida M, Matsuoka M, Morishita K, Yuki K, Hanyu A, Miyazawa K, Inazawa J, Miyazono K, Imamura T.
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| J Biol Chem 284(5):3334-44. Epub 2008 Dec 1.
2009
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| 15 | PRDM16
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| PRDM16: the interconvertible adipo-myocyte switch.
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| Frühbeck G, Sesma P, Burrell MA.
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| Trends Cell Biol 19(4):141-6. Epub 2009 Mar 13.
2009
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| 16 | BMP7, PRDM16, UCP1
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| New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure.
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| Tseng YH, Kokkotou E, Schulz TJ, Huang TL, Winnay JN, Taniguchi CM, Tran TT, Suzuki R, Espinoza DO, Yamamoto Y, Ahrens MJ, Dudley AT, Norris AW, Kulkarni RN, Kahn CR.
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| Nature 454(7207):1000-4.
2008
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| 17 | PRDM16
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| PRDM16 controls a brown fat/skeletal muscle switch.
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| Seale P, Bjork B, Yang W, Kajimura S, Chin S, Kuang S, Scimè A, Devarakonda S, Conroe HM, Erdjument-Bromage H, Tempst P, Rudnicki MA, Beier DR, Spiegelman BM.
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| Nature 454(7207):961-7.
2008
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| 18 | PRDM16
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| Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.
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| Kajimura S, Seale P, Tomaru T, Erdjument-Bromage H, Cooper MP, Ruas JL, Chin S, Tempst P, Lazar MA, Spiegelman BM.
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| Genes Dev 22(10):1397-409.
2008
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| 19 | PRDM16, RUNX1
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| Identification of truncated RUNX1 and RUNX1-PRDM16 fusion transcripts in a case of t(1;21)(p36;q22)-positive therapy-related AML.
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| Stevens-Kroef MJ, Schoenmakers EF, van Kraaij M, Huys E, Vermeulen S, van der Reijden B, van Kessel AG.
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| Leukemia 20(6):1187-9. No abstract available.
2006
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| 20 | RUNX1, PRDM16
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| Overexpression of PRDM16 in the presence and absence of the RUNX1/PRDM16 fusion gene in myeloid leukemias.
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| Hazourli S, Chagnon P, Sauvageau M, Fetni R, Busque L, Hebert J.
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| Genes Chromosomes Cancer 45(11):1072-6. No abstract available. 2006
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| 21 | PRDM16
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| MEL1S, not MEL1, is overexpressed in myelodysplastic syndromes patients with t(1;3)(p36;q21).
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| Xiao Z, Zhang M, Liu X, Zhang Y, Yang L, Hao Y.
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| Leuk Res 30(3):332-4. Epub 2005 Aug 15. 2006
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| 22 | RUNX1, PRDM16
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| Novel RUNX1-PRDM16 fusion transcripts in a patient with acute myeloid leukemia showing t(1;21)(p36;q22).
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| Sakai I, Tamura T, Narumi H, Uchida N, Yakushijin Y, Hato T, Fujita S, Yasukawa M.
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| Genes Chromosomes Cancer 44(3):265-70. 2005
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| 23 | MDS1, MECOM, PRDM16
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| Molecular characterization of a t(1;3)(p36;q21) in a patient with MDS. MEL1 is widely expressed in normal tissues, including bone marrow, and it is not overexpressed in the t(1;3) cells.
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| Lahortiga I, Agirre X, Belloni E, Vazquez I, Larrayoz MJ, Gasparini P, Lo Coco F, Pelicci PG, Calasanz MJ, Odero MD.
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| Oncogene 23(1):311-6. 2004
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| 24 | PRDM16
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| Aberrant expression of the MEL1S gene identified in association with hypomethylation in adult T-cell leukemia cells.
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| Yoshida M, Nosaka K, Yasunaga J, Nishikata I, Morishita K, Matsuoka M.
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| Blood 103(7):2753-60. Epub 2003 Dec 4. 2004
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| 25 | PRDM16
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| A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation.
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| Nishikata I, Sasaki H, Iga M, Tateno Y, Imayoshi S, Asou N, Nakamura T, Morishita K.
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| Blood 102(9):3323-32. Epub 2003 Jun 19.
2003
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| 26 | PRDM16
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| A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 geneand is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells.
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| Mochizuki N, Shimizu S, Nagasawa T, Tanaka H, Taniwaki M, Yokota J,Morishita K.
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| Blood 96(9):3209-14. 2000
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| 27 | ACAP3, AMBRA1, CMIP, CNTNAP3, CNTNAP4, CPEB4, DAB2IP, DDHD1, DISP2, EEPD1, EXOC4, FAM40A, HELZ2, ITPRIP, KIAA1683, KIAA1712, KIAA1715, KIAA1737, KIAA1751, KIAA1755, KIF21A, MTMR12, PHACTR1, PHF21A, PRDM16, RAPH1, RHOXF1, SEMA4B, SEMA4C, SET7, SH3BP5L, SPHKAP, SSH2, TET1, TEX2, TNKS1BP1, UBE2O, UNC13A, UNK, WNK2, ZCCHC2, ZFHX2, ZNF407, ZNF436
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| Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
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| Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O.
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| DNA Res 7(6):347-55. 2000
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| 28 | PRDM5, PRDM7, PRDM6, PRDM14, PRDM11, PRDM12, PRDM13, PRDM16, PRDM8, PRDM9
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| The yin-yang of PR-domain family genes in tumorigenesis.
|
| Jiang GL, Huang S.
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| Histol Histopathol 15(1):109-17. Review. 2000
|