1 | FLT1, PPP3R1
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| Macrophage Wnt-Calcineurin-Flt1 signaling regulates mouse wound angiogenesis and repair.
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| Stefater JA 3rd, Rao S, Bezold K, Aplin AC, Nicosia RF, Pollard JW, Ferrara N, Lang RA.
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| Blood 121(13):2574-8. doi: 10.1182/blood-2012-06-434621. Epub 2013 Jan 9. Erratum in: Blood. 2013 Sep 26;122(13):2290.
2013
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2 | PPP3R1, TRAF3
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| TRAF3 negatively regulates calcineurin-NFAT pathway by targeting calcineurin B subunit for degradation.
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| Wang X, Huang Y, Li L, Wei Q.
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| IUBMB Life 64(9):748-56. doi: 10.1002/iub.1060. Epub 2012 Jun 20.
2012
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3 | PPP3R1
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| Calcineurin B subunit acts as a potential agent for preventing cardiac ischemia/reperfusion injury.
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| Guo J, Mi S, Li J, Liu W, Yin Y, Wei Q.
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| Mol Cell Biochem 370(1-2):163-71. doi: 10.1007/s11010-012-1407-7. Epub 2012 Aug 28.
2012
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4 | PPP3R1, TNFSF10
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| The calcineurin B subunit induces TNF-related apoptosis-inducing ligand (TRAIL) expression via CD11b-NF-κB pathway in RAW264.7 macrophages.
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| Su Z, Xin S, Xu L, Cheng J, Guo J, Li L, Wei Q.
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| Biochem Biophys Res Commun 417(2):777-83. doi: 10.1016/j.bbrc.2011.12.034. Epub 2011 Dec 16.
2012
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5 | HIF1A, PPP3R1, PSMA7
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| Calcineurin B subunit interacts with proteasome subunit alpha type 7 and represses hypoxia-inducible factor-1α activity via the proteasome pathway.
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| Li N, Zhang Z, Zhang W, Wei Q.
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| Biochem Biophys Res Commun 405(3):468-72. doi: 10.1016/j.bbrc.2011.01.055. Epub 2011 Jan 20.
2011
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6 | CIB1, CIB2, PPP3CA, PPP3R1
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| CIB1 is a regulator of pathological cardiac hypertrophy.
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| Heineke J, Auger-Messier M, Correll RN, Xu J, Benard MJ, Yuan W, Drexler H, Parise LV, Molkentin JD.
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| Nat Med 16(8):872-9. Epub 2010 Jul 18.PMID: 20639889 2010
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7 | PPP3R1
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| Overexpression of calcineurin B subunit (CnB) enhances the oncogenic potential of HEK293 cells.
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| Wang YL, Wang Y, Tong L, Wei Q.
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| Cancer Sci 99(6):1100-8. doi: 10.1111/j.1349-7006.2008.00799.x. Epub 2008 Apr 14.
2008
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8 | PPP3R1
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| Conditional disruption of calcineurin B1 in osteoblasts increases bone formation and reduces bone resorption.
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| Yeo H, Beck LH, Thompson SR, Farach-Carson MC, McDonald JM, Clemens TL, Zayzafoon M.
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| J Biol Chem 282(48):35318-27. Epub 2007 Sep 19.
2007
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9 | PPP3R1, MAP3K5
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| Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth.
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| Liu Q, Wilkins BJ, Lee YJ, Ichijo H, Molkentin JD.
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| Mol Cell Biol 26(10):3785-97. 2006
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10 | PPP3R1, PPP3R2, PPP3CA, PPP3CB, PPP3CC
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| Calcineurin regulates bone formation by the osteoblast.
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| Sun L, Blair HC, Peng Y, Zaidi N, Adebanjo OA, Wu XB, Wu XY, Iqbal J, Epstein S, Abe E, Moonga BS, Zaidi M.
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| Proc Natl Acad Sci U S A 102(47):17130-5. Epub 2005 Nov 14. 2005
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11 | PPP3R1
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| Identification of a novel 5-base pair deletion in calcineurin B (PPP3R1) promoter region and its association with left ventricular hypertrophy.
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| Tang W, Arnett DK, Devereux RB, Panagiotou D, Province MA, Miller MB, de Simone G, Gu C, Ferrell RE.
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| Am Heart J 150(4):845-51. 2005
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12 | NFATC4, PPP3R1
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| Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature.
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| Graef IA, Chen F, Chen L, Kuo A, Crabtree GR.
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| Cell 105(7):863-75. 2001
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13 | PPP3R1
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| Structure of the gene coding for calcineurin B (PPP3R1) and mapping to D2S358-D2S1778 (chromosomal region 2p15).
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| Stratakis CA, Taymans SE.
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| DNA Seq 9(4):227-30. 1998
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14 | PPP3CA, PPP3CB, PPP3R1
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| Calcineurin A alpha (PPP3CA), calcineurin A beta (PPP3CB) and calcineurin B (PPP3R1) are located on human chromosomes 4, 10q21-q22 and 2p16-p15 respectively.
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| Wang MG, et al.
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| Cytogenet Cell Genet 72 : 236-241. 1996
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15 | PPP3R1
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| Highly polymorphic sequence variation in calcineurin B coding region (PPP3R1).
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| Lin MJ, et al.
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| Hum Mol Genet 3 : 520. 1994
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