1 | AHCTF1, PPP1CC
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| A Nucleoporin Docks Protein Phosphatase 1 to Direct Meiotic Chromosome Segregation and Nuclear Assembly.
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| Hattersley N, Cheerambathur D, Moyle M, Stefanutti M, Richardson A, Lee KY, Dumont J, Oegema K, Desai A.
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| Dev Cell 38(5):463-77. doi: 10.1016/j.devcel.2016.08.006.
2016
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2 | NEK1, PDS5B, PPP1CC, WAPL
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| Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1γ-WAPL Axis in the Mouse.
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| Brieño-Enríquez MA, Moak SL, Toledo M, Filter JJ, Gray S, Barbero JL, Cohen PE, Holloway JK.
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| Cell Rep 17(4):977-986. doi: 10.1016/j.celrep.2016.09.059.
2016
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3 | MYD88, PPP1CC, TRAF6
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| Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-γ.
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| Opaluch AM, Schneider M, Chiang CY, Nguyen QT, Maestre AM, Mulder LC, Secundino I, De Jesus PD, König R, Simon V, Nizet V, MacLeod G, Varmuza S, Fernandez-Sesma A, Chanda SK.
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| PLoS One 9(2):e89284. doi: 10.1371/journal.pone.0089284. eCollection 2014.
2014
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4 | LPIN1, PPP1CC
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| Conserved residues in the N terminus of lipin-1 are required for binding to protein phosphatase-1c, nuclear translocation, and phosphatidate phosphatase activity.
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| Kok BP, Skene-Arnold TD, Ling J, Benesch MG, Dewald J, Harris TE, Holmes CF, Brindley DN.
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| J Biol Chem 289(15):10876-86. doi: 10.1074/jbc.M114.552612. Epub 2014 Feb 20.
2014
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5 | PPP1CA, PPP1CB, PPP1CC
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| Phosphoprotein phosphatase 1 complexes in spermatogenesis.
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| Silva JV, Freitas MJ, Fardilha M.
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| Curr Mol Pharmacol 7(2):136-46.
2014
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6 | PHACTR4, PPP1CC
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| Actin-regulated feedback loop based on Phactr4, PP1 and cofilin maintains the actin monomer pool.
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| Huet G, Rajakylä EK, Viita T, Skarp KP, Crivaro M, Dopie J, Vartiainen MK.
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| J Cell Sci 126(Pt 2):497-507. doi: 10.1242/jcs.113241. Epub 2012 Nov 30.
2013
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7 | DDX58, IFIH1, PPP1CA, PPP1CC
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| Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling.
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| Wies E, Wang MK, Maharaj NP, Chen K, Zhou S, Finberg RW, Gack MU.
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| Immunity 38(3):437-49. doi: 10.1016/j.immuni.2012.11.018. Epub 2013 Mar 14.
2013
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8 | PPP1CC, TSKS, TSSK1B
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| PPP1CC2 can form a kinase/phosphatase complex with the testis-specific proteins TSSK1 and TSKS in the mouse testis.
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| MacLeod G, Shang P, Booth GT, Mastropaolo LA, Manafpoursakha N, Vogl AW, Varmuza S.
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| Reproduction 147(1):1-12. doi: 10.1530/REP-13-0224. Print 2014 Jan.
2013
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9 | PPP1CC, TCTEX1D4
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| TCTEX1D4, a novel protein phosphatase 1 interactor: connecting the phosphatase to the microtubule network.
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| Korrodi-Gregório L, Vieira SI, Esteves SL, Silva JV, Freitas MJ, Brauns AK, Luers G, Abrantes J, Esteves PJ, da Cruz E Silva OA, Fardilha M, da Cruz E Silva EF.
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| Biol Open 2(5):453-65. doi: 10.1242/bio.20131065. Print 2013 May 15.
2013
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10 | PHACTR4, PPP1CC
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| Phactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activity.
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| Zhang Y, Kim TH, Niswander L.
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| Genes Dev 26(1):69-81. doi: 10.1101/gad.179283.111.
2012
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11 | DDOST, PPP1CC
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| Tandem affinity purification in transgenic mouse embryonic stem cells identifies DDOST as a novel PPP1CC2 interacting protein.
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| MacLeod G, Varmuza S.
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| Biochemistry 51(48):9678-88. doi: 10.1021/bi3010158. Epub 2012 Nov 16.
2012
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12 | PPP1CC
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| Significant expression levels of transgenic PPP1CC2 in testis and sperm are required to overcome the male infertility phenotype of Ppp1cc null mice.
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| Sinha N, Pilder S, Vijayaraghavan S.
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| PLoS One 7(10):e47623. doi: 10.1371/journal.pone.0047623. Epub 2012 Oct 17.
2012
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13 | GEMIN8, PPP1CC
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| A role for protein phosphatase PP1γ in SMN complex formation and subnuclear localization to Cajal bodies.
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| Renvoisé B, Quérol G, Verrier ER, Burlet P, Lefebvre S.
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| J Cell Sci 125(Pt 12):2862-74. doi: 10.1242/jcs.096255. Epub 2012 Mar 27.
2012
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14 | PPP1CC, WWC1
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| KIBRA protein phosphorylation is regulated by mitotic kinase aurora and protein phosphatase 1.
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| Xiao L, Chen Y, Ji M, Volle DJ, Lewis RE, Tsai MY, Dong J.
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| J Biol Chem 286(42):36304-15. doi: 10.1074/jbc.M111.246850. Epub 2011 Aug 30.
2011
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15 | NEK2, PLK1, PPP1CC
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| Plk1 controls the Nek2A-PP1γ antagonism in centrosome disjunction.
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| Mardin BR, Agircan FG, Lange C, Schiebel E.
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| Curr Biol 21(13):1145-51. doi: 10.1016/j.cub.2011.05.047. Epub 2011 Jun 30.
2011
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16 | PPP1CC, PPP1R10, SETD1A, SETD1B, TOX4, WDR82
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| Identification and characterization of a novel human PP1 phosphatase complex.
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| Lee JH, You J, Dobrota E, Skalnik DG.
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| J Biol Chem 285(32):24466-76. Epub 2010 Jun 1.PMID: 20516061 2010
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17 | AURKA, AURKB, CENPE, PPP1CC
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| Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E.
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| Kim Y, Holland AJ, Lan W, Cleveland DW.
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| Cell 142(3):444-55. 2010
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18 | PPP1CC
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| Loss of protein phosphatase 1c{gamma} (PPP1CC) leads to impaired spermatogenesis associated with defects in chromatin condensation and acrosome development: an ultrastructural analysis.
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| Forgione N, Vogl AW, Varmuza S.
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| Reproduction 139(6):1021-9. doi: 10.1530/REP-10-0063. Epub 2010 Apr 12.
2010
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19 | IKZF1, PPP1CC
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| Ikaros stability and pericentromeric localization are regulated by protein phosphatase 1.
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| Popescu M, Gurel Z, Ronni T, Song C, Hung KY, Payne KJ, Dovat S.
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| J Biol Chem 284(20):13869-80. Epub 2009 Mar 11. 2009
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20 | PPP1CC
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| The catalytic subunit of protein phosphatase 1 gamma regulates thrombin-induced murine platelet alpha(IIb)beta(3) function.
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| Gushiken FC, Hyojeong H, Pradhan S, Langlois KW, Alrehani N, Cruz MA, Rumbaut RE, Vijayan KV.
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| PLoS One 4(12):e8304.PMID: 20016849 2009
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21 | AXIN1, DAB2, PPP1CC
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| Dab2 stabilizes Axin and attenuates Wnt/beta-catenin signaling by preventing protein phosphatase 1 (PP1)-Axin interactions.
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| Jiang Y, Luo W, Howe PH.
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| Oncogene 28(33):2999-3007. Epub 2009 Jul 6.PMID: 19581931 2009
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22 | PPP1CC, PPP1R11
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| PP1gamma2 and PPP1R11 are parts of a multimeric complex in developing testicular germ cells in which their steady state levels are reciprocally related.
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| Cheng L, Pilder S, Nairn AC, Ramdas S, Vijayaraghavan S.
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| PLoS One 4(3):e4861. Epub 2009 Mar 20.PMID: 19300506 2009
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23 | PPP1CC
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| Identification of a protective role for protein phosphatase 1cgamma1 against oxidative stress-induced vascular smooth muscle cell apoptosis.
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| Tchivilev I, Madamanchi NR, Vendrov AE, Niu XL, Runge MS.
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| J Biol Chem 283(32):22193-205. Epub 2008 Jun 7.PMID: 18540044 2008
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24 | PPP1CC
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| Association of protein phosphatase 1 gamma 1 with spinophilin suppresses phosphatase activity in a Parkinson disease model.
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| Brown AM, Baucum AJ, Bass MA, Colbran RJ.
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| J Biol Chem 283(21):14286-94. Epub 2008 Mar 26.PMID: 18372251 2008
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25 | PPP1CC
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| Selective targeting of the gamma1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin.
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| Carmody LC, Baucum AJ 2nd, Bass MA, Colbran RJ.
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| FASEB J 22(6):1660-71. Epub 2008 Jan 23.PMID: 18216290 2008
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26 | LBR, PPP1CC
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| Nuclear envelope precursor vesicle targeting to chromatin is stimulated by protein phosphatase 1 in Xenopus egg extracts.
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| Ito H, Koyama Y, Takano M, Ishii K, Maeno M, Furukawa K, Horigome T.
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| Exp Cell Res 313(9):1897-910. Epub 2007 Mar 24.PMID: 17448463 2007
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27 | PPP1CC
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| Analysis of Ppp1cc-null mice suggests a role for PP1gamma2 in sperm morphogenesis.
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| Chakrabarti R, Kline D, Lu J, Orth J, Pilder S, Vijayaraghavan S.
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| Biol Reprod 76(6):992-1001. Epub 2007 Feb 14.PMID: 17301292 2007
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28 | PPP1CC
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| Identification of a novel phosphatidic acid binding domain in protein phosphatase-1.
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| Jones JA, Rawles R, Hannun YA.
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| Biochemistry 44(40):13235-45.PMID: 16201749 2005
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29 | PPP1CC
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| Modulation of myosin phosphatase targeting subunit and protein phosphatase 1 in the heart.
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| Rajashree R, Blunt BC, Hofmann PA.
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| Am J Physiol Heart Circ Physiol 289(4):H1736-43. Epub 2005 May 20.PMID: 15908465 2005
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30 | ALDH2, ATP2A2, OAS1, PPP1CC, PTPN11, ATXN2
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| A sequence-ready physical map of a region of 12q24.1.
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| Renault B, Hovnanian A, Bryce S, Chang JJ, Lau S, Sakuntabhai A, Monk S, Carter S, Ross CJ, Pang J, Twells R, Chamberlain S, Monaco AP, Strachan T, Kucherlapati R.
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| Genomics 45(2):271-8. 1997
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31 | PPP1CC
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| Assignment of the gene encoding type I gamma protein phosphatase catalytic subunit (PPP1CC) on human, rat, and mouse chromosomes.
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| Saadat M, et al.
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| Jpn J Hum Genet 41 : 159-165. 1996
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32 | PPP1CC
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| Molecular cloning and chromosomal localization of a human skeletal muscle PP-1gamma1 cDNA.
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| Norman SA, et al.
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| Mamm Genome 5 : 41-45. 1994
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33 | PPP1CC
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| Sequence of human protein serine/threonine phosphatase 1 gamma and localization of the gene (PPP1CC) encoding it to chromosome bands 12q24.1-q24.2.
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| Barker HM, et al.
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| Biochim Biophys Acta 1178 : 228-233. 1993
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34 | PPP1CC
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| Localisation of protein serine/threonine phosphatase gamma (PPP1C) to 12q24.1-q24.2 by in situ hybridisation.
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| Craig SP, et al.
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| Cytogenet Cell Genet 61 : 254. 1992
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