| 1 | EIF2S1, PPP1CA, PPP1R15B
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| Homozygous mutation in the eukaryotic translation initiation factor 2alpha phosphatase gene, PPP1R15B, is associated with severe microcephaly, short stature and intellectual disability.
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| Kernohan KD, Tétreault M, Liwak-Muir U, Geraghty MT, Qin W, Venkateswaran S, Davila J; Care4Rare Canada Consortium, Holcik M, Majewski J, Richer J, Boycott KM.
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| Hum Mol Genet 24(22):6293-300. doi: 10.1093/hmg/ddv337. Epub 2015 Aug 24.
2015
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| 2 | LATS1, PARD3, PPP1CA, TAZ
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| PARD3 induces TAZ activation and cell growth by promoting LATS1 and PP1 interaction.
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| Lv XB, Liu CY, Wang Z, Sun YP, Xiong Y, Lei QY, Guan KL.
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| EMBO Rep 16(8):975-85. doi: 10.15252/embr.201439951. Epub 2015 Jun 26.
2015
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| 3 | PPP1CA, PPP1CB, PPP1CC
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| Phosphoprotein phosphatase 1 complexes in spermatogenesis.
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| Silva JV, Freitas MJ, Fardilha M.
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| Curr Mol Pharmacol 7(2):136-46.
2014
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| 4 | PPP1CA, YWHAZ
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| 14-3-3ζ regulates nuclear trafficking of protein phosphatase 1α (PP1α) in HEK-293 cells.
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| Jérôme M, Paudel HK.
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| Arch Biochem Biophys 558:28-35. doi: 10.1016/j.abb.2014.06.012. Epub 2014 Jun 20.
2014
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| 5 | DDX58, IFIH1, PPP1CA, PPP1CC
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| Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling.
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| Wies E, Wang MK, Maharaj NP, Chen K, Zhou S, Finberg RW, Gack MU.
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| Immunity 38(3):437-49. doi: 10.1016/j.immuni.2012.11.018. Epub 2013 Mar 14.
2013
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| 6 | PPP1CA, PREX1
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| The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1α
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| Barber MA, Hendrickx A, Beullens M, Ceulemans H, Oxley D, Thelen S, Thelen M, Bollen M, Welch HC.
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| Biochem J. Apr 1;443(1):173-83. doi: 10.1042/BJ20112078 2012
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| 7 | PPP1CA, TAZ, TP53BP2
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| PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.
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| Liu CY, Lv X, Li T, Xu Y, Zhou X, Zhao S, Xiong Y, Lei QY, Guan KL.
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| J Biol Chem 286(7):5558-66. doi: 10.1074/jbc.M110.194019. Epub 2010 Dec 28.
2011
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| 8 | PPP1CA, PPP1CB, TRIM28
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| SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1.
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| Li X, Lin HH, Chen H, Xu X, Shih HM, Ann DK.
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| Sci Signal 3(119):ra32. doi: 10.1126/scisignal.2000781.
2010
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| 9 | PPP1CA
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| Association of the tensin N-terminal protein-tyrosine phosphatase domain with the alpha isoform of protein phosphatase-1 in focal adhesions.
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| Eto M, Kirkbride J, Elliott E, Lo SH, Brautigan DL.
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| J Biol Chem 282(24):17806-15. Epub 2007 Apr 15. 2007
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| 10 | PER2, PPP1CA
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| Protein phosphatase 1 regulates the stability of the circadian protein PER2.
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| Gallego M, Kang H, Virshup DM.
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| Biochem J 399(1):169-75. 2006
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| 11 | PPP1CA
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| Gene amplification and overexpression of protein phosphatase 1alpha in oral squamous cell carcinoma cell lines.
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| Hsu LC, Huang X, Seasholtz S, Potter DM, Gollin SM.
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| Oncogene 25(40):5517-26. Epub 2006 Apr 17. 2006
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| 12 | CDCA2, PPP1CA
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| Repo-Man recruits PP1 gamma to chromatin and is essential for cell viability.
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| Trinkle-Mulcahy L, Andersen J, Lam YW, Moorhead G, Mann M, Lamond AI.
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| J Cell Biol 172(5):679-92. Epub 2006 Feb 21. 2006
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| 13 | PPP1CA
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| Comparative mapping of the gene encoding the catalytic subunit of protein phosphatase type 1alpha (PPP1CA) to human, rat, and mouse chromosomes.
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| Saadat M, et al.
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| Cytogenet Cell Genet 70 : 55-57. 1995
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| 14 | PPP1CA, D11S2072
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| Dinucleotide repeat polymorphism at the PPP1CA locus on 11q13.
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| Mochizuki H, et al.
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| Hum Mol Genet 3 : 2265. 1994
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| 15 | PPP1CA
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| Cloning and characterization of a human protein phosphatase 1-encoding cDNA.
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| Song Q, Khanna KK, Lu H, Lavin MF.
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| Gene 129(2):291-5. 1993
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| 16 | PPP1CA, RBP1
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| The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit.
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| Durfee T, Becherer K, Chen PL, Yeh SH, Yang Y, Kilburn AE, Lee WH, Elledge SJ.
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| Genes Dev 7(4):555-69. 1993
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| 17 | PPP1CA
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| Protein phosphatase type 1 in mammalian cell mitosis : chromosomal localization and involvement in mitotic exit.
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| Fernandez A, et al.
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| J Cell Biol 116 : 1421-1430. 1992
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| 18 | PPP1CA
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| Localization of the gene encoding a type I protein phosphatase catalytic subunit to human chromosome band 11q13.
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| Barker HM, et al.
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| Genomics 7 : 159-166. 1990
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