Citations for
N-Myristoylation is essential for protein phosphatases PPM1A and PPM1B to dephosphorylate their physiological substrates in cells.
Chida T, Ando M, Matsuki T, Masu Y, Nagaura Y, Takano-Yamamoto T, Tamura S, Kobayashi T.
Biochem J 449(3):741-9. doi: 10.1042/BJ20121201. 2013
Inhibition of TGF-β signaling at the nuclear envelope: characterization of interactions between MAN1, Smad2 and Smad3, and PPM1A.
Bourgeois B, Gilquin B, Tellier-Lebčgue C, Östlund C, Wu W, Pérez J, El Hage P, Lallemand F, Worman HJ, Zinn-Justin S.
Sci Signal 6(280):ra49. doi: 10.1126/scisignal.2003411. 2013
Phosphatase PPM1A negatively regulates P-TEFb function in resting CD4(+) T cells and inhibits HIV-1 gene expression.
Budhiraja S, Ramakrishnan R, Rice AP.
Retrovirology 9:52. doi: 10.1186/1742-4690-9-52. 2012
Protein phosphatase magnesium dependent 1A (PPM1A) plays a role in the differentiation and survival processes of nerve cells.
Shohat M, Ben-Meir D, Lavi S.
PLoS One 7(2):e32438. doi: 10.1371/journal.pone.0032438. Epub 2012 Feb 27. 2012
PPM1A dephosphorylates RanBP3 to enable efficient nuclear export of Smad2 and Smad3.
Dai F, Shen T, Li Z, Lin X, Feng XH.
EMBO Rep 12(11):1175-81. doi: 10.1038/embor.2011.174. 2011
Protein phosphatase 1A (PPM1A) is involved in human cytotrophoblast cell invasion and migration.
Zhang B, Zhou Z, Lin H, Lv X, Fu J, Lin P, Zhu C, Wang H.
Histochem Cell Biol 132(2):169-79. doi: 10.1007/s00418-009-0601-5. Epub 2009 Apr 29. 2009
PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activation.
Sun W, Yu Y, Dotti G, Shen T, Tan X, Savoldo B, Pass AK, Chu M, Zhang D, Lu X, Fu S, Lin X, Yang J.
Cell Signal 21(1):95-102. doi: 10.1016/j.cellsig.2008.09.012. Epub 2008 Oct 1. 2009
Phosphatase PPM1A regulates phosphorylation of Thr-186 in the Cdk9 T-loop.
Wang Y, Dow EC, Liang YY, Ramakrishnan R, Liu H, Sung TL, Lin X, Rice AP.
J Biol Chem 283(48):33578-84. doi: 10.1074/jbc.M807495200. Epub 2008 Oct 1. 2008
A phosphatase controls the fate of receptor-regulated Smads.
Schilling SH, Datto MB, Wang XF.
Cell 125(5):838-40. Review. 2006
PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling.
Lin X, Duan X, Liang YY, Su Y, Wrighton KH, Long J, Hu M, Davis CM, Wang J, Brunicardi FC, Shi Y, Chen YG, Meng A, Feng XH.
Cell 125(5):915-28. 2006
Cell cycle regulation and p53 activation by protein phosphatase 2C alpha.
Ofek P, Ben-Meir D, Kariv-Inbal Z, Oren M, Lavi S.
J Biol Chem 278(16):14299-305. Epub 2003 Jan 3. 2003
Protein phosphatase 2Calpha expression in normal human tissues: an immunohistochemical study.
Lifschitz-Mercer B, Sheinin Y, Ben-Meir D, Bramante-Schreiber L, Leider-Trejo L, Karby S, Smorodinsky NI, Lavi S.
Histochem Cell Biol 116(1):31-9. 2001
Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription.
Strovel ET, Wu D, Sussman DJ.
J Biol Chem 275(4):2399-403. 2000
Kinetic analysis of human serine/threonine protein phosphatase 2Calpha.
Fjeld CC, Denu JM.
J Biol Chem 274(29):20336-43. 1999
Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNKMAPK pathways.
Takekawa M, Maeda T, Saito H.
EMBO J 17(16):4744-52. 1998
Crystal structure of the protein serine/threonine phosphatase 2C at 2.0 Aresolution.
Das AK, Helps NR, Cohen PT, Barford D.
EMBO J 15(24):6798-809. 1996
Mammalian protein serine/threonine phosphatase 2C: cDNA cloning and comparativeanalysis of amino acid sequences.
Mann DJ, Campbell DG, McGowan CH, Cohen PT.
Biochim Biophys Acta 1130(1):100-4. 1992