1 | PPM1A, PPM1M, PPM1N
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| Metal-dependent Ser/Thr protein phosphatase PPM family: Evolution, structures, diseases and inhibitors.
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| Kamada R, Kudoh F, Ito S, Tani I, Janairo JIB, Omichinski JG, Sakaguchi K.
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| Pharmacol Ther. Nov;215:107622. doi: 10.1016/j.pharmthera.2020.107622. Epub 2020 Jul 7. 2020
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2 | PPM1A, TRIM52
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| Tripartite motif protein 52 (TRIM52) promoted fibrosis in LX-2 cells through PPM1A-mediated Smad2/3 pathway.
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| Zhou J, Lan Q, Li W, Yang L, You J, Zhang YM, Ni W.
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| Cell Biol Int. Jul 22. doi: 10.1002/cbin.11206. Online ahead of print 2019
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3 | PPM1A, PPM1B
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| N-Myristoylation is essential for protein phosphatases PPM1A and PPM1B to dephosphorylate their physiological substrates in cells.
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| Chida T, Ando M, Matsuki T, Masu Y, Nagaura Y, Takano-Yamamoto T, Tamura S, Kobayashi T.
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| Biochem J 449(3):741-9. doi: 10.1042/BJ20121201.
2013
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4 | LEMD3, PPM1A, SMAD2, SMAD3
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| Inhibition of TGF-β signaling at the nuclear envelope: characterization of interactions between MAN1, Smad2 and Smad3, and PPM1A.
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| Bourgeois B, Gilquin B, Tellier-Lebčgue C, Östlund C, Wu W, Pérez J, El Hage P, Lallemand F, Worman HJ, Zinn-Justin S.
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| Sci Signal 6(280):ra49. doi: 10.1126/scisignal.2003411.
2013
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5 | PPM1A
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| Phosphatase PPM1A negatively regulates P-TEFb function in resting CD4(+) T cells and inhibits HIV-1 gene expression.
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| Budhiraja S, Ramakrishnan R, Rice AP.
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| Retrovirology 9:52. doi: 10.1186/1742-4690-9-52.
2012
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6 | PPM1A
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| Protein phosphatase magnesium dependent 1A (PPM1A) plays a role in the differentiation and survival processes of nerve cells.
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| Shohat M, Ben-Meir D, Lavi S.
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| PLoS One 7(2):e32438. doi: 10.1371/journal.pone.0032438. Epub 2012 Feb 27.
2012
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7 | PPM1A, RANBP3
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| PPM1A dephosphorylates RanBP3 to enable efficient nuclear export of Smad2 and Smad3.
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| Dai F, Shen T, Li Z, Lin X, Feng XH.
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| EMBO Rep 12(11):1175-81. doi: 10.1038/embor.2011.174.
2011
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8 | PPM1A
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| Protein phosphatase 1A (PPM1A) is involved in human cytotrophoblast cell invasion and migration.
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| Zhang B, Zhou Z, Lin H, Lv X, Fu J, Lin P, Zhu C, Wang H.
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| Histochem Cell Biol 132(2):169-79. doi: 10.1007/s00418-009-0601-5. Epub 2009 Apr 29.
2009
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9 | IKBKB, PPM1A, PPM1B
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| PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activation.
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| Sun W, Yu Y, Dotti G, Shen T, Tan X, Savoldo B, Pass AK, Chu M, Zhang D, Lu X, Fu S, Lin X, Yang J.
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| Cell Signal 21(1):95-102. doi: 10.1016/j.cellsig.2008.09.012. Epub 2008 Oct 1.
2009
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10 | PPM1A
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| Phosphatase PPM1A regulates phosphorylation of Thr-186 in the Cdk9 T-loop.
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| Wang Y, Dow EC, Liang YY, Ramakrishnan R, Liu H, Sung TL, Lin X, Rice AP.
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| J Biol Chem 283(48):33578-84. doi: 10.1074/jbc.M807495200. Epub 2008 Oct 1.
2008
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11 | PPM1A
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| A phosphatase controls the fate of receptor-regulated Smads.
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| Schilling SH, Datto MB, Wang XF.
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| Cell 125(5):838-40. Review. 2006
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12 | PPM1A
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| PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling.
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| Lin X, Duan X, Liang YY, Su Y, Wrighton KH, Long J, Hu M, Davis CM, Wang J, Brunicardi FC, Shi Y, Chen YG, Meng A, Feng XH.
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| Cell 125(5):915-28. 2006
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13 | PPM1A
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| Cell cycle regulation and p53 activation by protein phosphatase 2C alpha.
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| Ofek P, Ben-Meir D, Kariv-Inbal Z, Oren M, Lavi S.
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| J Biol Chem 278(16):14299-305. Epub 2003 Jan 3. 2003
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14 | PPM1A
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| Protein phosphatase 2Calpha expression in normal human tissues: an immunohistochemical study.
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| Lifschitz-Mercer B, Sheinin Y, Ben-Meir D, Bramante-Schreiber L, Leider-Trejo L, Karby S, Smorodinsky NI, Lavi S.
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| Histochem Cell Biol 116(1):31-9. 2001
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15 | PPM1A
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| Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription.
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| Strovel ET, Wu D, Sussman DJ.
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| J Biol Chem 275(4):2399-403. 2000
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16 | PPM1A
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| Kinetic analysis of human serine/threonine protein phosphatase 2Calpha.
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| Fjeld CC, Denu JM.
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| J Biol Chem 274(29):20336-43. 1999
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17 | PPM1A
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| Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNKMAPK pathways.
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| Takekawa M, Maeda T, Saito H.
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| EMBO J 17(16):4744-52. 1998
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18 | PPM1A
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| Crystal structure of the protein serine/threonine phosphatase 2C at 2.0 Aresolution.
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| Das AK, Helps NR, Cohen PT, Barford D.
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| EMBO J 15(24):6798-809. 1996
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19 | PPM1A
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| Mammalian protein serine/threonine phosphatase 2C: cDNA cloning and comparativeanalysis of amino acid sequences.
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| Mann DJ, Campbell DG, McGowan CH, Cohen PT.
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| Biochim Biophys Acta 1130(1):100-4. 1992
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