Citations for
1PPIF
CypD deficiency confers neuroprotection against mitochondrial abnormality caused by lead in SH-SY5Y cell.
Ye F, Li X, Liu Y, Jiang A, Li X, Yang L, Chang W, Yuan J, Chen J.
Toxicol Lett 323:25-34. doi: 10.1016/j.toxlet.2019.12.025. Epub 2019 Dec 23. 2020
2PPIF
Delineating a role for the mitochondrial permeability transition pore in diabetic kidney disease by targeting cyclophilin D.
Lindblom RSJ, Higgins GC, Nguyen TV, Arnstein M, Henstridge DC, Granata C, Snelson M, Thallas-Bonke V, Cooper ME, Forbes JM, Coughlan MT.
Clin Sci (Lond) 134(2):239-259. doi: 10.1042/CS20190787. 2020
3PPIF
Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD.
Karch J, Bround MJ, Khalil H, Sargent MA, Latchman N, Terada N, Peixoto PM, Molkentin JD.
Sci Adv 5(8):eaaw4597. doi: 10.1126/sciadv.aaw4597. eCollection 2019 Aug. 2019
4PPIF, STAR
Cyclophilin D participates in the inhibitory effect of high-fat diet on the expression of steroidogenic acute regulatory protein.
Su X, Lin D, Luo D, Sun M, Wang X, Ye J, Zhang M, Zhang Y, Xu X, Yu C, Guan Q.
J Cell Mol Med 23(10):6859-6871. doi: 10.1111/jcmm.14569. Epub 2019 Aug 1. 2019
5PPIF
Cyclophilin D deficiency protects against the development of mitochondrial ROS and cellular inflammation in aorta.
Liu X, Du H, Chen D, Yuan H, Chen W, Jia W, Wang X, Li X, Gao L.
Biochem Biophys Res Commun 508(4):1202-1208. doi: 10.1016/j.bbrc.2018.12.064. Epub 2018 Dec 13. 2019
6PPIF
Cyclophilin D, Somehow a Master Regulator of Mitochondrial Function.
Porter GA Jr, Beutner G.
Biomolecules 8(4). pii: E176. doi: 10.3390/biom8040176. Review. 2018
7PPIF
Cyclophilin D regulates neuronal activity-induced filopodiagenesis by fine-tuning dendritic mitochondrial calcium dynamics.
Sui S, Tian J, Gauba E, Wang Q, Guo L, Du H.
J Neurochem 146(4):403-415. doi: 10.1111/jnc.14484. Epub 2018 Aug 16. 2018
8PPIF
Cyclophilin D deficiency attenuates mitochondrial perturbation and ameliorates hepatic steatosis.
Wang X, Du H, Shao S, Bo T, Yu C, Chen W, Zhao L, Li Q, Wang L, Liu X, Su X, Sun M, Song Y, Gao L, Zhao J.
Hepatology 68(1):62-77. doi: 10.1002/hep.29788. Epub 2018 May 9. 2018
9PPIF
Cyclophilin D regulates the dynamic assembly of mitochondrial ATP synthase into synthasomes.
Beutner G, Alanzalon RE, Porter GA Jr.
Sci Rep 7(1):14488. doi: 10.1038/s41598-017-14795-x. 2017
10PPIF
Cyclophilin D regulates lifespan and protein expression of aging markers in the brain of mice.
Vereczki V, Mansour J, Pour-Ghaz I, Bodnar I, Pinter O, Zelena D, Oszwald E, Adam-Vizi V, Chinopoulos C.
Mitochondrion 34:115-126. doi: 10.1016/j.mito.2017.03.003. Epub 2017 Mar 10. 2017
11PPIF
Cyclophilin D over-expression increases mitochondrial complex III activity and accelerates supercomplex formation.
Etzler JC, Bollo M, Holstein D, Deng JJ, Perez V, Lin DT, Richardson A, Bai Y, Lechleiter JD.
Arch Biochem Biophys 613:61-68. doi: 10.1016/j.abb.2016.11.008. Epub 2016 Dec 1. 2017
12PPIA, PPIB, PPIC, PPID, PPIE, PPIF
Identification of low abundance cyclophilins in human plasma.
Schumann M, Ihling CH, Prell E, Schierhorn A, Sinz A, Fischer G, Schiene-Fischer C, Malešević M.
Proteomics 16(21):2815-2826. doi: 10.1002/pmic.201600221. Epub 2016 Oct 12. 2016
13PPIF
Mitochondrial Thioredoxin System as a Modulator of Cyclophilin D Redox State.
Folda A, Citta A, Scalcon V, Calì T, Zonta F, Scutari G, Bindoli A, Rigobello MP.
Sci Rep 6:23071. doi: 10.1038/srep23071. 2016
14PPIF, TFB2M
Cyclophilin-D: a resident regulator of mitochondrial gene expression.
Radhakrishnan J, Bazarek S, Chandran B, Gazmuri RJ.
FASEB J 29(7):2734-48. doi: 10.1096/fj.14-263855. Epub 2015 Apr 2. 2015
15PPIF, SPG7
SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore.
Shanmughapriya S, Rajan S, Hoffman NE, Higgins AM, Tomar D, Nemani N, Hines KJ, Smith DJ, Eguchi A, Vallem S, Shaikh F, Cheung M, Leonard NJ, Stolakis RS, Wolfers MP, Ibetti J, Chuprun JK, Jog NR, Houser SR, Koch WJ, Elrod JW, Madesh M.
Mol Cell 60(1):47-62. doi: 10.1016/j.molcel.2015.08.009. Epub 2015 Sep 17. 2015
16PPIF
Structural mechanisms of cyclophilin D-dependent control of the mitochondrial permeability transition pore.
Gutiérrez-Aguilar M, Baines CP.
Biochim Biophys Acta 1850(10):2041-7. doi: 10.1016/j.bbagen.2014.11.009. Epub 2014 Nov 13. Review. 2015
17PPIF
Inhibition of cyclophilin D by cyclosporin A promotes retinal ganglion cell survival by preventing mitochondrial alteration in ischemic injury.
Kim SY, Shim MS, Kim KY, Weinreb RN, Wheeler LA, Ju WK.
Cell Death Dis 5:e1105. doi: 10.1038/cddis.2014.80. 2014
18PPIF
Cyclophilin D extramitochondrial signaling controls cell cycle progression and chemokine-directed cell motility.
Tavecchio M, Lisanti S, Lam A, Ghosh JC, Martin NM, O'Connell M, Weeraratna AT, Kossenkov AV, Showe LC, Altieri DC.
J Biol Chem 288(8):5553-61. doi: 10.1074/jbc.M112.433045. Epub 2013 Jan 9. 2013
19PPIF
Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons.
Guo L, Du H, Yan S, Wu X, McKhann GM, Chen JX, Yan SS.
PLoS One 8(1):e54914. doi: 10.1371/journal.pone.0054914. Epub 2013 Jan 31. 2013
20PPIF
Cyclophilin D modulates mitochondrial acetylome.
Nguyen TT, Wong R, Menazza S, Sun J, Chen Y, Wang G, Gucek M, Steenbergen C, Sack MN, Murphy E.
Circ Res 113(12):1308-19. doi: 10.1161/CIRCRESAHA.113.301867. Epub 2013 Sep 23. 2013
21PPIF
Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons.
Guo L, Du H, Yan S, Wu X, McKhann GM, Chen JX, Yan SS.
PLoS One 8(1):e54914. doi: 10.1371/journal.pone.0054914. Epub 2013 Jan 31. 2013
22PPIF
Human coronavirus-induced neuronal programmed cell death is cyclophilin d dependent and potentially caspase dispensable.
Favreau DJ, Meessen-Pinard M, Desforges M, Talbot PJ.
J Virol 86(1):81-93. doi: 10.1128/JVI.06062-11. Epub 2011 Oct 19. 2012
23C1QBP, PPIF
Complement 1q-binding protein inhibits the mitochondrial permeability transition pore and protects against oxidative stress-induced death.
McGee AM, Baines CP.
Biochem J 433(1):119-25. doi: 10.1042/BJ20101431. 2011
24PPIF
Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice.
Elrod JW, Wong R, Mishra S, Vagnozzi RJ, Sakthievel B, Goonasekera SA, Karch J, Gabel S, Farber J, Force T, Brown JH, Murphy E, Molkentin JD.
J Clin Invest 120(10):3680-7. doi: 10.1172/JCI43171. Epub 2010 Sep 20. 2010
25PPIF
Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells.
Carreira RS, Lee Y, Ghochani M, Gustafsson ÅB, Gottlieb RA.
Autophagy 6(4):462-72. doi: 10.4161/auto.6.4.11553. Epub 2010 May 16. 2010
26HSPD1, PPIF
Heat shock protein 60 regulation of the mitochondrial permeability transition pore in tumor cells.
Ghosh JC, Siegelin MD, Dohi T, Altieri DC.
Cancer Res 70(22):8988-93. doi: 10.1158/0008-5472.CAN-10-2225. Epub 2010 Oct 26. 2010
27PPID, PPIF
Cyclophilin D interacts with Bcl2 and exerts an anti-apoptotic effect.
Eliseev RA, Malecki J, Lester T, Zhang Y, Humphrey J, Gunter TE.
J Biol Chem 284(15):9692-9. Epub 2009 Feb 19. 2009
28PPID, PPIF
Cyclophilin D is expressed predominantly in mitochondria of gamma-aminobutyric acidergic interneurons.
Hazelton JL, Petrasheuskaya M, Fiskum G, Kristián T.
J Neurosci Res 87(5):1250-9. 2009
29PPIF
The mitochondrial phosphate carrier interacts with cyclophilin D and may play a key role in the permeability transition.
Leung AW, Varanyuwatana P, Halestrap AP.
J Biol Chem 283(39):26312-23. doi: 10.1074/jbc.M805235200. Epub 2008 Jul 30. 2008
30PPID, PPIF
Role of cyclophilin D in the resistance of brain mitochondria to the permeability transition.
Eliseev RA, Filippov G, Velos J, VanWinkle B, Goldman A, Rosier RN, Gunter TE.
Neurobiol Aging 28(10):1532-42. Epub 2006 Jul 31. 2007
31PPIF
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia.
Schinzel AC, Takeuchi O, Huang Z, Fisher JK, Zhou Z, Rubens J, Hetz C, Danial NN, Moskowitz MA, Korsmeyer SJ.
Proc Natl Acad Sci U S A 102(34):12005-10. Epub 2005 Aug 15. 2005
32PPIF
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death.
Nakagawa T, Shimizu S, Watanabe T, Yamaguchi O, Otsu K, Yamagata H, Inohara H, Kubo T, Tsujimoto Y.
Nature 434(7033):652-8. 2005
33PPIF
Mitochondrial targeted cyclophilin D protects cells from cell death by peptidyl prolyl isomerization.
Lin DT, Lechleiter JD.
J Biol Chem 277(34):31134-41. Epub 2002 Jun 19. 2002
34ARVD7, CMD1C, POLR3A, PPIF
Construction of a high-resolution physical map of the chromosome 10q22-q23 dilated cardiomyopathy locus and analysis of candidate genes.
Bowles KR, Abraham SE, Brugada R, Zintz C, Comeaux J, Sorajja D, Tsubata S, Li H, Brandon L, Gibbs RA, Scherer SE, Bowles NE, Towbin JA.
Genomics 67(2):109-27. 2000
35PPIF
Genomic characterization of the human peptidyl-prolyl-cis-trans-isomerase, mitochondrial precursor gene: assessment of its role in familial dilated cardiomyopathy.
Bowles KR, Zintz C, Abraham SE, Brandon L, Bowles NE, Towbin JA.
Hum Genet 105(6):582-6 1999
36PPIF
The cyclophilin multigene family of peptidyl-prolyl isomerases. Characterization of three separate human isoforms.
Bergsma DJ, Eder C, Gross M, Kersten H, Sylvester D, Appelbaum E, Cusimano D, Livi GP, McLaughlin MM, Kasyan K, et al.
J Biol Chem 266(34):23204-14. 1991