Citations for
1BSG, PPIA
Cyclophilin A and CD147 associate with progression of diabetic nephropathy.
Chiu PF, Su SL, Tsai CC, Wu CL, Kuo CL, Kor CT, Chang CC, Liu CS.
Free Radic Res 52(11-12):1456-1463. doi: 10.1080/10715762.2018.1523545. Epub 2018 Dec 20. 2018
2ITCH, PPIA
CypA Regulates AIP4-Mediated M1 Ubiquitination of Influenza A Virus.
Mahesutihan M, Zheng W, Cui L, Li Y, Jiao P, Yang W, Liu W, Li J, Fan W, Yang L, Liu W, Sun L.
Virol Sin 33(5):440-448. doi: 10.1007/s12250-018-0058-6. Epub 2018 Oct 16. 2018
3PPIA
The clinical implication of serum cyclophilin A in patients with chronic obstructive pulmonary disease.
Zhang M, Tang J, Yin J, Wang X, Feng X, Yang X, Shan H, Zhang Q, Zhang J, Li Y.
Int J Chron Obstruct Pulmon Dis 13:357-363. doi: 10.2147/COPD.S152898. eCollection 2018. 2018
4PPIA
Cyclophilin A expression and its prognostic significance in lung adenocarcinoma.
Nakano N, Sakashita S, Matsuoka R, Murata Y, Shiba-Ishii A, Kobayashi N, Sato Y, Noguchi M.
Pathol Int 67(11):555-563. doi: 10.1111/pin.12593. Epub 2017 Oct 12. 2017
5PPIA
Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation.
von Ungern-Sternberg SNI, Vogel S, Walker-Allgaier B, Geue S, Maurer A, Wild AM, Münzer P, Chatterjee M, Heinzmann D, Kremmer E, Borst O, Loughran P, Zernecke A, Neal MD, Billiar TR, Gawaz M, Seizer P.
Thromb Haemost 117(11):2063-2078. doi: 10.1160/TH17-01-0067. Epub 2017 Nov 30. 2017
6BSG, PPIA
Potential role of cyclophilin A in regulating cytokine secretion.
Dawar FU, Xiong Y, Khattak MNK, Li J, Lin L, Mei J.
J Leukoc Biol 102(4):989-992. doi: 10.1189/jlb.3RU0317-090RR. Epub 2017 Jul 20. Review. 2017
7AIFM1, PPIA
Structural and biochemical insights of CypA and AIF interaction.
Farina B, Di Sorbo G, Chambery A, Caporale A, Leoni G, Russo R, Mascanzoni F, Raimondo D, Fattorusso R, Ruvo M, Doti N.
Sci Rep 7(1):1138. doi: 10.1038/s41598-017-01337-8. 2017
8PPIA
Cyclophilin A: A Key Factor in Virus Replication and Potential Target for Anti-viral Therapy.
Dawar FU, Tu J, Khattak MN, Mei J, Lin L.
Curr Issues Mol Biol 21:1-20. Epub 2016 Mar 31. Review. 2017
9PPIA, PPIB, PPIC, PPID, PPIE, PPIF
Identification of low abundance cyclophilins in human plasma.
Schumann M, Ihling CH, Prell E, Schierhorn A, Sinz A, Fischer G, Schiene-Fischer C, Malešević M.
Proteomics 16(21):2815-2826. doi: 10.1002/pmic.201600221. Epub 2016 Oct 12. 2016
10BSG, PPIA
CD147 stimulates hepatoma cells escaping from immune surveillance of T cells by interaction with Cyclophilin A.
Ren YX, Wang SJ, Fan JH, Sun SJ, Li X, Padhiar AA, Zhang JN.
Biomed Pharmacother 80:289-297. doi: 10.1016/j.biopha.2016.03.036. Epub 2016 Apr 1. 2016
11PPIA
Cyclophilin A (CypA) Plays Dual Roles in Regulation of Bone Anabolism and Resorption.
Guo M, James AW, Kwak JH, Shen J, Yokoyama KK, Ting K, Soo CB, Chiu RH.
Sci Rep 6:22378. doi: 10.1038/srep22378. 2016
12MAP3K5, PPIA
Cyclophilin A regulates JNK/p38-MAPK signaling through its physical interaction with ASK1.
Kim H, Oh Y, Kim K, Jeong S, Chon S, Kim D, Jung MH, Pak YK, Ha J, Kang I, Choe W.
Biochem Biophys Res Commun 464(1):112-7. doi: 10.1016/j.bbrc.2015.06.078. Epub 2015 Jun 19. Erratum in: Biochem Biophys Res Commun. 2018 Jul 12;502(2):290. 2015
13PPIA, SOX9
Novel role for cyclophilin A in regulation of chondrogenic commitment and endochondral ossification.
Guo M, Shen J, Kwak JH, Choi B, Lee M, Hu S, Zhang X, Ting K, Soo CB, Chiu RH.
Mol Cell Biol 35(12):2119-30. doi: 10.1128/MCB.01414-14. Epub 2015 Apr 13. Erratum in: Mol Cell Biol. 2017 Aug 28;37(18):. 2015
14PPIA, RELA
Cyclophilin A (CypA) interacts with NF-κB subunit, p65/RelA, and contributes to NF-κB activation signaling.
Sun S, Guo M, Zhang JB, Ha A, Yokoyama KK, Chiu RH.
PLoS One 9(8):e96211. doi: 10.1371/journal.pone.0096211. eCollection 2014. 2014
15PPIA
Cyclophilin A catalyzes proline isomerization by an electrostatic handle mechanism.
Camilloni C, Sahakyan AB, Holliday MJ, Isern NG, Zhang F, Eisenmesser EZ, Vendruscolo M.
Proc Natl Acad Sci U S A 111(28):10203-8. doi: 10.1073/pnas.1404220111. Epub 2014 Jun 30. 2014
16AIFM1, PPIA
Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress.
Doti N, Reuther C, Scognamiglio PL, Dolga AM, Plesnila N, Ruvo M, Culmsee C.
Cell Death Dis 5:e993. doi: 10.1038/cddis.2013.518. 2014
17PPIA
Plasma cyclophilin A is a novel biomarker for coronary artery disease.
Satoh K, Fukumoto Y, Sugimura K, Miura Y, Aoki T, Nochioka K, Tatebe S, Miyamichi-Yamamoto S, Shimizu T, Osaki S, Takagi Y, Tsuburaya R, Ito Y, Matsumoto Y, Nakayama M, Takeda M, Takahashi J, Ito K, Yasuda S, Shimokawa H.
Circ J 77(2):447-55. Epub 2012 Nov 8. 2013
18PPIA
Cyclophilin A and viral infections.
Zhou D, Mei Q, Li J, He H.
Biochem Biophys Res Commun 424(4):647-50. doi: 10.1016/j.bbrc.2012.07.024. Epub 2012 Jul 16. Review. 2012
19PPIA
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.
Bell RD, Winkler EA, Singh I, Sagare AP, Deane R, Wu Z, Holtzman DM, Betsholtz C, Armulik A, Sallstrom J, Berk BC, Zlokovic BV.
Nature 485(7399):512-6. doi: 10.1038/nature11087. 2012
20PPIA
The peptidyl prolyl isomerase cyclophilin A localizes at the centrosome and the midbody and is required for cytokinesis.
Bannon JH, O'Donovan DS, Kennelly SM, Mc Gee MM.
Cell Cycle 11(7):1340-53. doi: 10.4161/cc.19711. Epub 2012 Apr 1. 2012
21PPIA
Cyclophilin A promotes cardiac hypertrophy in apolipoprotein E-deficient mice.
Satoh K, Nigro P, Zeidan A, Soe NN, Jaffré F, Oikawa M, O'Dell MR, Cui Z, Menon P, Lu Y, Mohan A, Yan C, Blaxall BC, Berk BC.
Arterioscler Thromb Vasc Biol 31(5):1116-23. doi: 10.1161/ATVBAHA.110.214601. Epub 2011 Feb 17. 2011
22PPIA
Cyclophilin A is involved in functional expression of the Na(+)-Ca(2+) exchanger NCX1.
Elbaz B, Valitsky M, Davidov G, Rahamimoff H.
Biochemistry 49(35):7634-42. 2010
23PPIA
Prolyl isomerase cyclophilin A regulation of Janus-activated kinase 2 and the progression of human breast cancer.
Zheng J, Koblinski JE, Dutson LV, Feeney YB, Clevenger CV.
Cancer Res 68(19):7769-78. doi: 10.1158/0008-5472.CAN-08-0639. 2008
24GABARAP, PPIA, RAB24
Human RAB24, interestingly and predominantly distributed in the nuclei of COS-7 cells, is colocalized with cyclophilin A and GABARAP.
Wu M, Yin G, Zhao X, Ji C, Gu S, Tang R, Dong H, Xie Y, Mao Y.
Int J Mol Med 17(5):749-54. 2006
25PPIA
Function of HAb18G/CD147 in invasion of host cells by severe acute respiratory syndrome coronavirus.
Chen Z, Mi L, Xu J, Yu J, Wang X, Jiang J, Xing J, Shang P, Qian A, Li Y, Shaw PX, Wang J, Duan S, Ding J, Fan C, Zhang Y, Yang Y, Yu X, Feng Q, Li B, Yao X, Zhang Z, Li L, Xue X, Zhu P.
J Infect Dis. 191(5):755-60. 2005
26PPIA
Identification of cyclophilin A as a CD99-binding protein by yeast two-hybrid screening.
Kim HJ, Chong KH, Kang SW, Lee JR, Kim JY, Hahn MJ, Kim TJ.
Immunol Lett. 95(2):155-9. 2004
27PPIA
Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1.
Sayah DM, Sokolskaja E, Berthoux L, Luban J.
Nature. 430(6999):569-73. 2004
28PPIA
A novel and functional interaction between cyclophilin A and prolactin receptor.
Syed F, Rycyzyn MA, Westgate L, Clevenger CV.
Endocrine. 20(1-2):83-90. 2003
29ITK, PPIA
Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A.
Brazin KN, Mallis RJ, Fulton DB, Andreotti AH.
Proc Natl Acad Sci U S A 99(4):1899-904. 2002
30PPIA, PPIB
Interaction with glycosaminoglycans is required for cyclophilin B to trigger integrin-mediated adhesion of peripheral blood T lymphocytes to extracellular matrix.
Allain F, Vanpouille C, Carpentier M, Slomianny MC, Durieux S, Spik G.
Proc Natl Acad Sci U S A 99(5):2714-9. 2002
31PPIA
Catalysis of cis/trans isomerization in native HIV-1 capsid by human cyclophilin A.
Bosco DA, Eisenmesser EZ, Pochapsky S, Sundquist WI, Kern D.
Proc Natl Acad Sci U S A 99(8):5247-52. 2002
32PPIA
Active site residues of cyclophilin A are crucial for its signaling activity via CD147.
Yurchenko V, Zybarth G, O'Connor M, Dai WW, Franchin G, Hao T, Guo H, Hung HC, Toole B, Gallay P, Sherry B, Bukrinsky M.
J Biol Chem. 277(25):22959-65. 2002
33PPIA
Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes.
Huai Q, Kim HY, Liu Y, Zhao Y, Mondragon A, Liu JO, Ke H.
Proc Natl Acad Sci U S A. 99(19):12037-42. 2002
34BSG, PPIA, PPIB
CD147 is a signaling receptor for cyclophilin B.
Yurchenko V, O'Connor M, Dai WW, Guo H, Toole B, Sherry B, Bukrinsky M.
Biochem Biophys Res Commun 288(4):786-8. 2001
35PPIA
Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells.
Braaten D, Luban J.
EMBO J. 20(6):1300-9. 2001
36PPIA
CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A.
Pushkarsky T, Zybarth G, Dubrovsky L, Yurchenko V, Tang H, Guo H, Toole B, Sherry B, Bukrinsky M.
Proc Natl Acad Sci U S A. 98(11):6360-5. 2001
37PPIA
Assignment of cyclophilin A (PPIA) to human chromosome band 7p13 by in situ hybridization.
Braaten D, et al.
Cytogenet Cell Genet 74 : 262. 1996
38PPIA
Cyclophilin-A is a zinc-dependent DNA binding protein in macrophages.
Krummrei U, et al.
FEBS Lett 371 : 47-51. 1995
39PPIA, PPIAP12, PPIAP13, PPIAP14, PPIAP16
Cyclophilin A, the major intracellular receptor for the immunosuppressant cyclosporin A, maps to chromosome 7p11.2-p13 : four pseudogenes map to chromosomes 3, 10, 14 and 18.
Willenbrink W, et al.
Genomics 28 : 101-104 1995
40PPIA
Cyclophilin A and FKBP12 interact with YY1 and alter its transcriptional activity.
Yang WM, Inouye CJ, Seto E.
J Biol Chem. 270(25):15187-93. 1995
41PPIA, PPIAT, PPIAP6, PPIAP11, PPIAP15, PPIAP7
Characterization of the human cyclophilin gene and of related processed pseudogenes.
Haendler B, Hofer E.
Eur J Biochem 190(3):477-82. 1990