1 | BSG, PPIA
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| Cyclophilin A and CD147 associate with progression of diabetic nephropathy.
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| Chiu PF, Su SL, Tsai CC, Wu CL, Kuo CL, Kor CT, Chang CC, Liu CS.
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| Free Radic Res 52(11-12):1456-1463. doi: 10.1080/10715762.2018.1523545. Epub 2018 Dec 20.
2018
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2 | ITCH, PPIA
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| CypA Regulates AIP4-Mediated M1 Ubiquitination of Influenza A Virus.
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| Mahesutihan M, Zheng W, Cui L, Li Y, Jiao P, Yang W, Liu W, Li J, Fan W, Yang L, Liu W, Sun L.
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| Virol Sin 33(5):440-448. doi: 10.1007/s12250-018-0058-6. Epub 2018 Oct 16.
2018
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3 | PPIA
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| The clinical implication of serum cyclophilin A in patients with chronic obstructive pulmonary disease.
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| Zhang M, Tang J, Yin J, Wang X, Feng X, Yang X, Shan H, Zhang Q, Zhang J, Li Y.
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| Int J Chron Obstruct Pulmon Dis 13:357-363. doi: 10.2147/COPD.S152898. eCollection 2018.
2018
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4 | PPIA
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| Cyclophilin A expression and its prognostic significance in lung adenocarcinoma.
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| Nakano N, Sakashita S, Matsuoka R, Murata Y, Shiba-Ishii A, Kobayashi N, Sato Y, Noguchi M.
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| Pathol Int 67(11):555-563. doi: 10.1111/pin.12593. Epub 2017 Oct 12.
2017
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5 | PPIA
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| Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation.
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| von Ungern-Sternberg SNI, Vogel S, Walker-Allgaier B, Geue S, Maurer A, Wild AM, Münzer P, Chatterjee M, Heinzmann D, Kremmer E, Borst O, Loughran P, Zernecke A, Neal MD, Billiar TR, Gawaz M, Seizer P.
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| Thromb Haemost 117(11):2063-2078. doi: 10.1160/TH17-01-0067. Epub 2017 Nov 30.
2017
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6 | BSG, PPIA
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| Potential role of cyclophilin A in regulating cytokine secretion.
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| Dawar FU, Xiong Y, Khattak MNK, Li J, Lin L, Mei J.
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| J Leukoc Biol 102(4):989-992. doi: 10.1189/jlb.3RU0317-090RR. Epub 2017 Jul 20. Review.
2017
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7 | AIFM1, PPIA
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| Structural and biochemical insights of CypA and AIF interaction.
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| Farina B, Di Sorbo G, Chambery A, Caporale A, Leoni G, Russo R, Mascanzoni F, Raimondo D, Fattorusso R, Ruvo M, Doti N.
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| Sci Rep 7(1):1138. doi: 10.1038/s41598-017-01337-8.
2017
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8 | PPIA
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| Cyclophilin A: A Key Factor in Virus Replication and Potential Target for Anti-viral Therapy.
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| Dawar FU, Tu J, Khattak MN, Mei J, Lin L.
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| Curr Issues Mol Biol 21:1-20. Epub 2016 Mar 31. Review.
2017
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9 | PPIA, PPIB, PPIC, PPID, PPIE, PPIF
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| Identification of low abundance cyclophilins in human plasma.
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| Schumann M, Ihling CH, Prell E, Schierhorn A, Sinz A, Fischer G, Schiene-Fischer C, Malešević M.
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| Proteomics 16(21):2815-2826. doi: 10.1002/pmic.201600221. Epub 2016 Oct 12.
2016
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10 | BSG, PPIA
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| CD147 stimulates hepatoma cells escaping from immune surveillance of T cells by interaction with Cyclophilin A.
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| Ren YX, Wang SJ, Fan JH, Sun SJ, Li X, Padhiar AA, Zhang JN.
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| Biomed Pharmacother 80:289-297. doi: 10.1016/j.biopha.2016.03.036. Epub 2016 Apr 1.
2016
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11 | PPIA
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| Cyclophilin A (CypA) Plays Dual Roles in Regulation of Bone Anabolism and Resorption.
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| Guo M, James AW, Kwak JH, Shen J, Yokoyama KK, Ting K, Soo CB, Chiu RH.
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| Sci Rep 6:22378. doi: 10.1038/srep22378.
2016
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12 | MAP3K5, PPIA
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| Cyclophilin A regulates JNK/p38-MAPK signaling through its physical interaction with ASK1.
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| Kim H, Oh Y, Kim K, Jeong S, Chon S, Kim D, Jung MH, Pak YK, Ha J, Kang I, Choe W.
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| Biochem Biophys Res Commun 464(1):112-7. doi: 10.1016/j.bbrc.2015.06.078. Epub 2015 Jun 19. Erratum in: Biochem Biophys Res Commun. 2018 Jul 12;502(2):290. 2015
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13 | PPIA, SOX9
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| Novel role for cyclophilin A in regulation of chondrogenic commitment and endochondral ossification.
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| Guo M, Shen J, Kwak JH, Choi B, Lee M, Hu S, Zhang X, Ting K, Soo CB, Chiu RH.
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| Mol Cell Biol 35(12):2119-30. doi: 10.1128/MCB.01414-14. Epub 2015 Apr 13. Erratum in: Mol Cell Biol. 2017 Aug 28;37(18):.
2015
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14 | PPIA, RELA
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| Cyclophilin A (CypA) interacts with NF-κB subunit, p65/RelA, and contributes to NF-κB activation signaling.
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| Sun S, Guo M, Zhang JB, Ha A, Yokoyama KK, Chiu RH.
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| PLoS One 9(8):e96211. doi: 10.1371/journal.pone.0096211. eCollection 2014.
2014
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15 | PPIA
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| Cyclophilin A catalyzes proline isomerization by an electrostatic handle mechanism.
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| Camilloni C, Sahakyan AB, Holliday MJ, Isern NG, Zhang F, Eisenmesser EZ, Vendruscolo M.
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| Proc Natl Acad Sci U S A 111(28):10203-8. doi: 10.1073/pnas.1404220111. Epub 2014 Jun 30.
2014
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16 | AIFM1, PPIA
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| Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress.
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| Doti N, Reuther C, Scognamiglio PL, Dolga AM, Plesnila N, Ruvo M, Culmsee C.
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| Cell Death Dis 5:e993. doi: 10.1038/cddis.2013.518.
2014
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17 | PPIA
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| Plasma cyclophilin A is a novel biomarker for coronary artery disease.
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| Satoh K, Fukumoto Y, Sugimura K, Miura Y, Aoki T, Nochioka K, Tatebe S, Miyamichi-Yamamoto S, Shimizu T, Osaki S, Takagi Y, Tsuburaya R, Ito Y, Matsumoto Y, Nakayama M, Takeda M, Takahashi J, Ito K, Yasuda S, Shimokawa H.
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| Circ J 77(2):447-55. Epub 2012 Nov 8.
2013
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18 | PPIA
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| Cyclophilin A and viral infections.
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| Zhou D, Mei Q, Li J, He H.
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| Biochem Biophys Res Commun 424(4):647-50. doi: 10.1016/j.bbrc.2012.07.024. Epub 2012 Jul 16. Review.
2012
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19 | PPIA
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| Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.
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| Bell RD, Winkler EA, Singh I, Sagare AP, Deane R, Wu Z, Holtzman DM, Betsholtz C, Armulik A, Sallstrom J, Berk BC, Zlokovic BV.
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| Nature 485(7399):512-6. doi: 10.1038/nature11087.
2012
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20 | PPIA
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| The peptidyl prolyl isomerase cyclophilin A localizes at the centrosome and the midbody and is required for cytokinesis.
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| Bannon JH, O'Donovan DS, Kennelly SM, Mc Gee MM.
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| Cell Cycle 11(7):1340-53. doi: 10.4161/cc.19711. Epub 2012 Apr 1.
2012
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21 | PPIA
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| Cyclophilin A promotes cardiac hypertrophy in apolipoprotein E-deficient mice.
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| Satoh K, Nigro P, Zeidan A, Soe NN, Jaffré F, Oikawa M, O'Dell MR, Cui Z, Menon P, Lu Y, Mohan A, Yan C, Blaxall BC, Berk BC.
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| Arterioscler Thromb Vasc Biol 31(5):1116-23. doi: 10.1161/ATVBAHA.110.214601. Epub 2011 Feb 17.
2011
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22 | PPIA
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| Cyclophilin A is involved in functional expression of the Na(+)-Ca(2+) exchanger NCX1.
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| Elbaz B, Valitsky M, Davidov G, Rahamimoff H.
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| Biochemistry 49(35):7634-42.
2010
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23 | PPIA
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| Prolyl isomerase cyclophilin A regulation of Janus-activated kinase 2 and the progression of human breast cancer.
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| Zheng J, Koblinski JE, Dutson LV, Feeney YB, Clevenger CV.
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| Cancer Res 68(19):7769-78. doi: 10.1158/0008-5472.CAN-08-0639.
2008
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24 | GABARAP, PPIA, RAB24
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| Human RAB24, interestingly and predominantly distributed in the nuclei of COS-7 cells, is colocalized with cyclophilin A and GABARAP.
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| Wu M, Yin G, Zhao X, Ji C, Gu S, Tang R, Dong H, Xie Y, Mao Y.
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| Int J Mol Med 17(5):749-54.
2006
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25 | PPIA
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| Function of HAb18G/CD147 in invasion of host cells by severe acute respiratory syndrome coronavirus.
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| Chen Z, Mi L, Xu J, Yu J, Wang X, Jiang J, Xing J, Shang P, Qian A, Li Y, Shaw PX, Wang J, Duan S, Ding J, Fan C, Zhang Y, Yang Y, Yu X, Feng Q, Li B, Yao X, Zhang Z, Li L, Xue X, Zhu P.
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| J Infect Dis. 191(5):755-60. 2005
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26 | PPIA
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| Identification of cyclophilin A as a CD99-binding protein by yeast two-hybrid screening.
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| Kim HJ, Chong KH, Kang SW, Lee JR, Kim JY, Hahn MJ, Kim TJ.
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| Immunol Lett. 95(2):155-9. 2004
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27 | PPIA
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| Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1.
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| Sayah DM, Sokolskaja E, Berthoux L, Luban J.
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| Nature. 430(6999):569-73. 2004
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28 | PPIA
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| A novel and functional interaction between cyclophilin A and prolactin receptor.
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| Syed F, Rycyzyn MA, Westgate L, Clevenger CV.
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| Endocrine. 20(1-2):83-90. 2003
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29 | ITK, PPIA
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| Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A.
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| Brazin KN, Mallis RJ, Fulton DB, Andreotti AH.
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| Proc Natl Acad Sci U S A 99(4):1899-904. 2002
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30 | PPIA, PPIB
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| Interaction with glycosaminoglycans is required for cyclophilin B to trigger integrin-mediated adhesion of peripheral blood T lymphocytes to extracellular matrix.
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| Allain F, Vanpouille C, Carpentier M, Slomianny MC, Durieux S, Spik G.
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| Proc Natl Acad Sci U S A 99(5):2714-9. 2002
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31 | PPIA
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| Catalysis of cis/trans isomerization in native HIV-1 capsid by human cyclophilin A.
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| Bosco DA, Eisenmesser EZ, Pochapsky S, Sundquist WI, Kern D.
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| Proc Natl Acad Sci U S A 99(8):5247-52. 2002
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32 | PPIA
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| Active site residues of cyclophilin A are crucial for its signaling activity via CD147.
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| Yurchenko V, Zybarth G, O'Connor M, Dai WW, Franchin G, Hao T, Guo H, Hung HC, Toole B, Gallay P, Sherry B, Bukrinsky M.
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| J Biol Chem. 277(25):22959-65. 2002
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33 | PPIA
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| Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes.
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| Huai Q, Kim HY, Liu Y, Zhao Y, Mondragon A, Liu JO, Ke H.
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| Proc Natl Acad Sci U S A. 99(19):12037-42. 2002
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34 | BSG, PPIA, PPIB
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| CD147 is a signaling receptor for cyclophilin B.
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| Yurchenko V, O'Connor M, Dai WW, Guo H, Toole B, Sherry B, Bukrinsky M.
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| Biochem Biophys Res Commun 288(4):786-8. 2001
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35 | PPIA
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| Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells.
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| Braaten D, Luban J.
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| EMBO J. 20(6):1300-9. 2001
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36 | PPIA
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| CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A.
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| Pushkarsky T, Zybarth G, Dubrovsky L, Yurchenko V, Tang H, Guo H, Toole B, Sherry B, Bukrinsky M.
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| Proc Natl Acad Sci U S A. 98(11):6360-5. 2001
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37 | PPIA
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| Assignment of cyclophilin A (PPIA) to human chromosome band 7p13 by in situ hybridization.
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| Braaten D, et al.
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| Cytogenet Cell Genet 74 : 262. 1996
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38 | PPIA
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| Cyclophilin-A is a zinc-dependent DNA binding protein in macrophages.
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| Krummrei U, et al.
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| FEBS Lett 371 : 47-51. 1995
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39 | PPIA, PPIAP12, PPIAP13, PPIAP14, PPIAP16
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| Cyclophilin A, the major intracellular receptor for the immunosuppressant cyclosporin A, maps to chromosome 7p11.2-p13 : four pseudogenes map to chromosomes 3, 10, 14 and 18.
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| Willenbrink W, et al.
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| Genomics 28 : 101-104 1995
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40 | PPIA
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| Cyclophilin A and FKBP12 interact with YY1 and alter its transcriptional activity.
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| Yang WM, Inouye CJ, Seto E.
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| J Biol Chem. 270(25):15187-93. 1995
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41 | PPIA, PPIAT, PPIAP6, PPIAP11, PPIAP15, PPIAP7
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| Characterization of the human cyclophilin gene and of related processed pseudogenes.
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| Haendler B, Hofer E.
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| Eur J Biochem 190(3):477-82. 1990
|