| 1 | MITF, PPARGC1AQ, PPARGC1B
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| PGC-1 coactivators regulate MITF and the tanning response.
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| Shoag J, Haq R, Zhang M, Liu L, Rowe GC, Jiang A, Koulisis N, Farrel C, Amos CI, Wei Q, Lee JE, Zhang J, Kupper TS, Qureshi AA, Cui R, Han J, Fisher DE, Arany Z.
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| Mol Cell 49(1):145-57. doi: 10.1016/j.molcel.2012.10.027. Epub 2012 Nov 29.
2013
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| 2 | MLXIPL, PPARGC1B
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| PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner.
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| Chambers KT, Chen Z, Lai L, Leone TC, Towle HC, Kralli A, Crawford PA, Finck BN.
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| Mol Metab 2(3):194-204. doi: 10.1016/j.molmet.2013.05.001. eCollection 2013.
2013
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| 3 | CHUK, PPARGC1B
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| IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism.
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| Bakkar N, Ladner K, Canan BD, Liyanarachchi S, Bal NC, Pant M, Periasamy M, Li Q, Janssen PM, Guttridge DC.
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| J Cell Biol 196(4):497-511. doi: 10.1083/jcb.201108118.
2012
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| 4 | LPIN1, NFE2L1, PPARGC1B
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| NF-E2-related factor 1 (Nrf1) serves as a novel regulator of hepatic lipid metabolism through regulation of the Lipin1 and PGC-1β genes.
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| Hirotsu Y, Hataya N, Katsuoka F, Yamamoto M.
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| Mol Cell Biol 32(14):2760-70. doi: 10.1128/MCB.06706-11. Epub 2012 May 14.
2012
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| 5 | PPARGC1B
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| PGC-1β deficiency accelerates the transition to heart failure in pressure overload hypertrophy.
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| Riehle C, Wende AR, Zaha VG, Pires KM, Wayment B, Olsen C, Bugger H, Buchanan J, Wang X, Moreira AB, Doenst T, Medina-Gomez G, Litwin SE, Lelliott CJ, Vidal-Puig A, Abel ED.
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| Circ Res 109(7):783-93. Epub 2011 Jul 28.
2011
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| 6 | PPARGC1B
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| Deletion of the metabolic transcriptional coactivator PGC1β induces cardiac arrhythmia.
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| Gurung IS, Medina-Gomez G, Kis A, Baker M, Velagapudi V, Neogi SG, Campbell M, Rodriguez-Cuenca S, Lelliott C, McFarlane I, Oresic M, Grace AA, Vidal-Puig A, Huang CL.
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| Cardiovasc Res 92(1):29-38. Epub 2011 Jun 1.
2011
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| 7 | PPARGC1B
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| Overexpression of PGC-1β improves insulin sensitivity and mitochondrial function in 3T3-L1 adipocytes.
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| Gao CL, Liu GL, Liu S, Chen XH, Ji CB, Zhang CM, Xia ZK, Guo XR.
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| Mol Cell Biochem 353(1-2):215-23. Epub 2011 Apr 16.
2011
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| 8 | PPARGC1B
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| PGC-1β regulates angiogenesis in skeletal muscle.
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| Rowe GC, Jang C, Patten IS, Arany Z.
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| Am J Physiol Endocrinol Metab 301(1):E155-63. Epub 2011 Mar 1.
2011
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| 9 | APOC3, PPARGC1B
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| Regulation of hepatic ApoC3 expression by PGC-1β mediates hypolipidemic effect of nicotinic acid.
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| Hernandez C, Molusky M, Li Y, Li S, Lin JD.
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| Cell Metab 12(4):411-9.
2010
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| 10 | ESRRA, NRF1, PPARGC1B
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| PGC-1 beta-regulated mitochondrial biogenesis and function in myotubes is mediated by NRF-1 and ERR alpha.
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| Shao D, Liu Y, Liu X, Zhu L, Cui Y, Cui A, Qiao A, Kong X, Liu Y, Chen Q, Gupta N, Fang F, Chang Y.
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| Mitochondrion 10(5):516-27. Epub 2010 May 31.
2010
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| 11 | PPARGC1A, PPARGC1B
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| Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy.
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| Brault JJ, Jespersen JG, Goldberg AL.
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| J Biol Chem 285(25):19460-71. Epub 2010 Apr 19.
2010
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| 12 | PPARGC1B, TFRC
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| Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation.
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| Ishii KA, Fumoto T, Iwai K, Takeshita S, Ito M, Shimohata N, Aburatani H, Taketani S, Lelliott CJ, Vidal-Puig A, Ikeda K.
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| Nat Med 15(3):259-66. Epub 2009 Mar 1.
2009
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| 13 | PPARGC1A, PPARGC1B
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| PGC-1{alpha} and PGC-1{beta} regulate mitochondrial density in neurons.
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| Wareski P, Vaarmann A, Choubey V, Safiulina D, Liiv J, Kuum M, Kaasik A.
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| J Biol Chem 284(32):21379-85. Epub 2009 Jun 19.
2009
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| 14 | PPARGC1B
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| Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta.
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| Liesa M, Borda-d'Agua B, Medina-Gómez G, Lelliott CJ, Paz JC, Rojo M, Palacín M, Vidal-Puig A, Zorzano A.
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| PLoS One 3(10):e3613. Epub 2008 Oct 31.
2008
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| 15 | PPARGC1B
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| PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis.
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| Sonoda J, Mehl IR, Chong LW, Nofsinger RR, Evans RM.
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| Proc Natl Acad Sci U S A 104(12):5223-8. Epub 2007 Mar 12.
2007
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| 16 | PPARGC1B
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| The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle.
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| Arany Z, Lebrasseur N, Morris C, Smith E, Yang W, Ma Y, Chin S, Spiegelman BM.
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| Cell Metab 5(1):35-46.
2007
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| 17 | PPARGC1B
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| Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity.
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| Andersen G, Wegner L, Yanagisawa K, Rose CS, Lin J, Glumer C, Drivsholm T, Borch-Johnsen K, Jorgensen T, Hansen T, Spiegelman BM, Pedersen O.
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| J Med Genet 42(5):402-7. 2005
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| 18 | SREBF1, HNF4A, PPARGC1B
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| SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.
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| Yamamoto T, Shimano H, Nakagawa Y, Ide T, Yahagi N, Matsuzaka T, Nakakuki M, Takahashi A, Suzuki H, Sone H, Toyoshima H, Sato R, Yamada N.
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| J Biol Chem 279(13):12027-35. Epub 2004 Jan 13. 2004
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| 19 | PPARGC1B
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| Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo.
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| Meirhaeghe A, Crowley V, Lenaghan C, Lelliott C, Green K, Stewart A, Hart K, Schinner S, Sethi JK, Yeo G, Brand MD, Cortright RN, O'Rahilly S, Montague C, Vidal-Puig AJ.
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| Biochem J 373(Pt 1):155-65. 2003
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| 20 | NCOA1, NCOA2, NCOA6, NRIP1, PPARGC1B, PHB2, SPEN
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| Combinatorial control of gene expression by nuclear receptors and coregulators.
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| McKenna NJ, O'Malley BW.
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| Cell 108(4):465-74. Review. 2002
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| 21 | CAMK4, PPARGC1A, PPARGC1B
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| Regulation of mitochondrial biogenesis in skeletal muscle by CaMK.
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| Wu H, Kanatous SB, Thurmond FA, Gallardo T, Isotani E, Bassel-Duby R, Williams RS.
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| Science 296(5566):349-52. 2002
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| 22 | PPARGC1A, PPARGC1B
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| A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes.
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| Hara K, Tobe K, Okada T, Kadowaki H, Akanuma Y, Ito C, Kimura S, Kadowaki T.
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| Diabetologia 45(5):740-3. Epub 2002 Apr 23. 2002
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| 23 | PPARGC1A, PPARGC1B
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| Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor.
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| Knutti D, Kressler D, Kralli A.
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| Proc Natl Acad Sci U S A 98(17):9713-8. 2001
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| 24 | PPARGC1A, PPARGC1B
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| Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1.
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| Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J, Adelmant G, Stafford J, Kahn CR, Granner DK, Newgard CB, Spiegelman BM.
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| Nature 413(6852):131-8. 2001
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| 25 | CREB1, PPARGC1A, PPARGC1B
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| CREB regulates hepatic gluconeogenesis through the coactivator PGC-1.
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| Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M.
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| Nature 413(6852):179-83. 2001
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| 26 | PPARGC1A, PPARGC1B
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| Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis.
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| Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP.
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| J Clin Invest 106(7):847-56. 2000
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| 27 | PPARGC1A, PPARGC1B
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| A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen.
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| Knutti D, Kaul A, Kralli A.
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| Mol Cell Biol 20(7):2411-22. 2000
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| 28 | PPARGC1A, PPARGC1B
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| Cloning and mRNA tissue distribution of human PPARgamma coactivator-1.
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| Larrouy D, Vidal H, Andreelli F, Laville M, Langin D.
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| Int J Obes Relat Metab Disord 23(12):1327-32. 1999
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| 29 | PPARGC1A, PPARGC1B
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| A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis.
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| Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM.
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| Cell 92(6):829-39. 1998
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