| 1 | PPARD, SLC1A5, SLC2A1
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| PPARδ promotes tumor progression via activation of Glut1 and SLC1-A5 transcription.
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| Zhang W, Xu Y, Xu Q, Shi H, Shi J, Hou Y.
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| Carcinogenesis 38(7):748-755. doi: 10.1093/carcin/bgx035.
2017
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| 2 | PPARD, PSMD2
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| An integrated approach of gene expression and DNA-methylation profiles of WNT signaling genes uncovers novel prognostic markers in acute myeloid leukemia.
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| Taskesen E, Staal FJ, Reinders MJ.
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| BMC Bioinformatics 16 Suppl 4:S4. doi: 10.1186/1471-2105-16-S4-S4.
2015
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| 3 | ACSL4, PPARD
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| PPARδ activation induces hepatic long-chain acyl-CoA synthetase 4 expression in vivo and in vitro.
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| Kan CF, Singh AB, Dong B, Shende VR, Liu J.
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| Biochim Biophys Acta 1851(5):577-87. doi: 10.1016/j.bbalip.2015.01.008. Epub 2015 Jan 31.
2015
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| 4 | ANGPTL4, PPARD
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| Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion.
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| Adhikary T, Brandt DT, Kaddatz K, Stockert J, Naruhn S, Meissner W, Finkernagel F, Obert J, Lieber S, Scharfe M, Jarek M, Toth PM, Scheer F, Diederich WE, Reinartz S, Grosse R, Müller-Brüsselbach S, Müller R.
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| Oncogene 32(44):5241-52. doi: 10.1038/onc.2012.549. Epub 2012 Dec 3.
2013
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| 5 | PLIN5, PPARD
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| Fatty acids regulate perilipin5 in muscle by activating PPARδ.
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| Bindesbĝll C, Berg O, Arntsen B, Nebb HI, Dalen KT.
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| J Lipid Res 54(7):1949-63. doi: 10.1194/jlr.M038992. Epub 2013 Apr 20.
2013
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| 6 | PPARD
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| Activation of peroxisome proliferator-activated receptor δ inhibits human macrophage foam cell formation and the inflammatory response induced by very low-density lipoprotein.
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| Bojic LA, Sawyez CG, Telford DE, Edwards JY, Hegele RA, Huff MW.
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| Arterioscler Thromb Vasc Biol 32(12):2919-28. doi: 10.1161/ATVBAHA.112.255208. Epub 2012 Sep 27.
2012
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| 7 | ANGPTL4, PPARD
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| Angiopoietin-like 4 mediates PPAR delta effect on lipoprotein lipase-dependent fatty acid uptake but not on beta-oxidation in myotubes.
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| Robciuc MR, Skrobuk P, Anisimov A, Olkkonen VM, Alitalo K, Eckel RH, Koistinen HA, Jauhiainen M, Ehnholm C.
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| PLoS One 7(10):e46212. doi: 10.1371/journal.pone.0046212. Epub 2012 Oct 4.
2012
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| 8 | PPARD
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| PPARδ activation protects endothelial function in diabetic mice.
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| Tian XY, Wong WT, Wang N, Lu Y, Cheang WS, Liu J, Liu L, Liu Y, Lee SS, Chen ZY, Cooke JP, Yao X, Huang Y.
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| Diabetes 61(12):3285-93. doi: 10.2337/db12-0117. Epub 2012 Aug 28.
2012
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| 9 | PPARD, PTEN
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| PPARδ coordinates angiotensin II-induced senescence in vascular smooth muscle cells through PTEN-mediated inhibition of superoxide generation.
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| Kim HJ, Ham SA, Kim MY, Hwang JS, Lee H, Kang ES, Yoo T, Woo IS, Yabe-Nishimura C, Paek KS, Kim JH, Seo HG.
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| J Biol Chem 286(52):44585-93. doi: 10.1074/jbc.M111.222562. Epub 2011 Nov 9.
2011
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| 10 | PPARD
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| Activation of peroxisome proliferators-activated receptor δ (PPARδ) promotes blastocyst hatching in mice.
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| Kang HJ, Hwang SJ, Yoon JA, Jun JH, Lim HJ, Yoon TK, Song H.
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| Mol Hum Reprod 17(10):653-60. doi: 10.1093/molehr/gar030. Epub 2011 Apr 20.
2011
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| 11 | PPARD
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| Vascular PPARδ protects against stroke-induced brain injury.
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| Yin KJ, Deng Z, Hamblin M, Zhang J, Chen YE.
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| Arterioscler Thromb Vasc Biol 31(3):574-81. doi: 10.1161/ATVBAHA.110.221267. Epub 2011 Jan 4.
2011
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| 12 | MMP9, PPARD, TGFA
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| AP1-dependent repression of TGFα-mediated MMP9 upregulation by PPARδ agonists in keratinocytes.
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| Meissner M, Berlinski B, Doll M, Hrgovic I, Laubach V, Reichenbach G, Kippenberger S, Gille J, Kaufmann R.
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| Exp Dermatol 20(5):425-9. doi: 10.1111/j.1600-0625.2011.01253.x.
2011
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| 13 | PPARD
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| Peroxisome proliferator-activated receptor {delta} is an essential transcriptional regulator for mitochondrial protection and biogenesis in adult heart.
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| Wang P, Liu J, Li Y, Wu S, Luo J, Yang H, Subbiah R, Chatham J, Zhelyabovska O, Yang Q.
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| Circ Res 106(5):911-9. doi: 10.1161/CIRCRESAHA.109.206185. Epub 2010 Jan 14.
2010
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| 14 | PPARD
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| Regulation of oligodendrocyte progenitor cell maturation by PPARδ: effects on bone morphogenetic proteins.
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| Vittoria Simonini M, Polak PE, Boullerne AI, Peters JM, Richardson JC, Feinstein DL.
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| ASN Neuro 2(1):e00025. doi: 10.1042/AN20090033.
2010
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| 15 | ABCA12, PPARD
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| Ceramide stimulates ABCA12 expression via peroxisome proliferator-activated receptor {delta} in human keratinocytes.
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| Jiang YJ, Uchida Y, Lu B, Kim P, Mao C, Akiyama M, Elias PM, Holleran WM, Grunfeld C, Feingold KR.
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| J Biol Chem 284(28):18942-52. Epub 2009 May 8.
2009
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| 16 | KLF5, PPARD
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| SUMOylation of Krppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta.
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| Oishi Y, Manabe I, Tobe K, Ohsugi M, Kubota T, Fujiu K, Maemura K, Kubota N, Kadowaki T, Nagai R.
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| Nat Med 14(6):656-66. Epub 2008 May 25. 2008
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| 17 | PPARD
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| Suppression of pro-inflammatory adhesion molecules by PPAR-delta in human vascular endothelial cells.
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| Fan Y, Wang Y, Tang Z, Zhang H, Qin X, Zhu Y, Guan Y, Wang X, Staels B, Chien S, Wang N.
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| Arterioscler Thromb Vasc Biol 28(2):315-21. Epub 2007 Nov 29.PMID: 18048767 2008
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| 18 | PPARD,UCP3
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| Low-intensity exercise increases skeletal muscle protein expression of PPARdelta and UCP3 in type 2 diabetic patients.
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| Fritz T, Kramer DK, Karlsson HK, Galuska D, Engfeldt P, Zierath JR, Krook A.
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| Diabetes Metab Res Rev 22(6):492-8. 2006
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| 19 | PPARD
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| Roles of peroxisome proliferator-activated receptor delta (PPARdelta) in the control of fatty acid catabolism. A new target for the treatment of metabolic syndrome.
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| Luquet S, Lopez-Soriano J, Holst D, Gaudel C, Jehl-Pietri C, Fredenrich A, Grimaldi PA.
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| Biochimie 86(11):833-7. Review. 2004
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| 20 | PPARD, PPARG
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| PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages.
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| Welch JS, Ricote M, Akiyama TE, Gonzalez FJ, Glass CK.
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| Proc Natl Acad Sci U S A 100(11):6712-7. Epub 2003 May 09. 2003
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| 21 | PPARD
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| PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs.
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| He TC, et al.
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| Cell 99(3):335-45 1999
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| 22 | PPARA, PPARD, DIDAN
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| Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors.
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| DiRenzo J, et al.
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| Mol Cell Biol 17 : 2166-2176. 1997
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| 23 | PPARD
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| Assignment of the human nuclear hormone receptor, NUC1 (PPARD), to chromosome 6p21.1-p21.2.
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| Yoshikawa T, et al.
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| Genomics 35 : 637-638. 1996
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