1 | POU3F2
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| BRN2 as a key gene drives the early primate telencephalon development.
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| Zhu X, Guo Y, Chu C, Liu D, Duan K, Yin Y, Si C, Kang Y, Yao J, Du X, Li J, Zhao S, Ai Z, Zhu Q, Ji W, Niu Y, Li T.
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| Sci Adv. Mar 4;8(9):eabl7263. doi: 10.1126/sciadv.abl7263. Epub 2022 Mar 4. 2022
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2 | POU3F2
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| Transcription factor POU3F2 regulates TRIM8 expression contributing to cellular functions implicated in schizophrenia.
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| Ding C, Zhang C, Kopp R, Kuney L, Meng Q, Wang L, Xia Y, Jiang Y, Dai R, Min S, Yao WD, Wong ML, Ruan H, Liu C, Chen C.
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| Mol Psychiatry. Jul;26(7):3444-3460. doi: 10.1038/s41380-020-00877-2. Epub 2020 Sep 14. 2021
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3 | NDDOTSA, POU3F2
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| De Novo Variants Disturbing the Transactivation Capacity of POU3F3 Cause a Characteristic Neurodevelopmental Disorder.
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| Snijders Blok L, Kleefstra T, Venselaar H, Maas S, Kroes HY, Lachmeijer AMA, van Gassen KLI, Firth HV, Tomkins S, Bodek S; DDD Study; Õunap K, Wojcik MH, Cunniff C, Bergstrom K, Powis Z, Tang S, Shinde DN, Au C, Iglesias AD, Izumi K, Leonard J, Abou Tayoun A, Baker SW, Tartaglia M, Niceta M, Dentici ML, Okamoto N, Miyake N, Matsumoto N, Vitobello A, Faivre L, Philippe C, Gilissen C, Wiel L, Pfundt R, Deriziotis P, Brunner HG, Fisher SE.
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| Am J Hum Genet. Aug 1;105(2):403-412. doi: 10.1016/j.ajhg.2019.06.007. Epub 2019 Jul 11. 2019
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4 | POU3F2
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| POU3F2 participates in cognitive function and adult hippocampal neurogenesis via mammalian-characteristic amino acid repeats
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| Hashizume K, Yamanaka M, Ueda S.
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| Genes Brain Behav. Feb;17(2):118-125. doi: 10.1111/gbb.12408. Epub 2017 Aug 30 2018
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5 | NTF3, POU3F2
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| NTF3 Is a Novel Target Gene of the Transcription Factor POU3F2 and Is Required for Neuronal Differentiation
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| Lin YJ, Hsin IL, Sun HS, Lin S, Lai YL, Chen HY, Chen TY, Chen YP, Shen YT, Wu HM.
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| Mol Neurobiol. Nov;55(11):8403-8413. doi: 10.1007/s12035-018-0995-y. Epub 2018 Mar 16. 2018
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6 | NDDOTSA, POU3F2
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| De Novo Missense Variant in POU3F2 Identified in a Child with Global Developmental Delay
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| Westphal DS, Riedhammer KM, Kovacs-Nagy R, Meitinger T, Hoefele J, Wagner M. A
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| Neuropediatrics. Dec;49(6):401-404. doi: 10.1055/s-0038-1669926. Epub 2018 Sep 10. 2018
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7 | MITF, POU3F2
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| MITF and BRN2 contribute to metastatic growth after dissemination of melanoma.
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| Simmons JL, Pierce CJ, Al-Ejeh F, Boyle GM.
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| Sci Rep. Sep 7;7(1):10909. doi: 10.1038/s41598-017-11366-y. 2017
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8 | DDIDO, POU3F2
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| Small 6q16.1 Deletions Encompassing POU3F2 Cause Susceptibility to Obesity and Variable Developmental Delay with Intellectual Disability.
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| Kasher PR, Schertz KE, Thomas M, Jackson A, Annunziata S, Ballesta-Martinez MJ, Campeau PM, Clayton PE, Eaton JL, Granata T, Guillén-Navarro E, Hernando C, Laverriere CE, Liedén A, Villa-Marcos O, McEntagart M, Nordgren A, Pantaleoni C, Pebrel-Richard C, Sarret C, Sciacca FL, Wright R, Kerr B, Glasgow E, Banka S.
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| Am J Hum Genet 98(2):363-72. doi: 10.1016/j.ajhg.2015.12.014. Epub 2016 Jan 28.
2016
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9 | NFIA, POU3F2, SOX9, ZBTB20
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| Zbtb20 promotes astrocytogenesis during neocortical development.
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| Nagao M, Ogata T, Sawada Y, Gotoh Y.
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| Nat Commun 7:11102. doi: 10.1038/ncomms11102.
2016
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10 | BRN1, EOMES, HES5, POU3F2, POU3F3
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| POU-III transcription factors (Brn1, Brn2, and Oct6) influence neurogenesis, molecular identity, and migratory destination of upper-layer cells of the cerebral cortex.
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| Dominguez MH, Ayoub AE, Rakic P.
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| Cereb Cortex 23(11):2632-43. doi: 10.1093/cercor/bhs252. Epub 2012 Aug 14.
2013
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11 | POU3F2
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| Phosphorylation of BRN2 modulates its interaction with the Pax3 promoter to control melanocyte migration and proliferation.
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| Berlin I, Denat L, Steunou AL, Puig I, Champeval D, Colombo S, Roberts K, Bonvin E, Bourgeois Y, Davidson I, Delmas V, Nieto L, Goding CR, Larue L.
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| Mol Cell Biol. 32(7):1237-47. 2012
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12 | ASCL1, MYT1L, POU3F2
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| Direct conversion of fibroblasts to functional neurons by defined factors.
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| Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Südhof TC, Wernig M.
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| Nature 463(7284):1035-41. Epub 2010 Jan 27.
2010
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13 | ARNT2, HD, POU3F2, SIM1
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| Mutant huntingtin fragment selectively suppresses Brn-2 POU domain transcription factor to mediate hypothalamic cell dysfunction.
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| Yamanaka T, Tosaki A, Miyazaki H, Kurosawa M, Furukawa Y, Yamada M, Nukina N.
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| Hum Mol Genet 19(11):2099-112. Epub 2010 Feb 25.PMID: 20185558 2010
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14 | POU3F2, POU3F3, SOX11
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| Expression of Sox11 and Brn transcription factors during development and following transient forebrain ischemia in the rat.
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| Kim DK, Han SB, Hong ST, Choi YJ, Sun W, Geum D, Kim H.
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| Neurosci Lett 433(3):259-64. doi: 10.1016/j.neulet.2008.01.016. Epub 2008 Jan 16. 2008
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15 | POU3F2
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| Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin.
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| Goodall J, Martinozzi S, Dexter TJ, Champeval D, Carreira S, Larue L, Goding CR.
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| Mol Cell Biol. 24(7):2915-22. 2004
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16 | CDK5, POU3F2, POU3F3
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| Transcriptional regulation of cortical neuron migration by POU domain factors.
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| McEvilly RJ, de Diaz MO, Schonemann MD, Hooshmand F, Rosenfeld MG.
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| Science 295(5559):1528-32. 2002
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17 | POU3F2
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| Domains of Brn-2 that mediate homodimerization and interaction with general and melanocytic transcription factors.
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| Smit DJ, Smith AG, Parsons PG, Muscat GE, Sturm RA.
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| Eur J Biochem. 267(21):6413-22. 2000
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18 | POU3F2, PQBP1
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| PQBP-1, a novel polyglutamine tract-binding protein, inhibits transcription activation by Brn-2 and affects cell survival.
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| Waragai M, Lammers CH, Takeuchi S, Imafuku I, Udagawa Y, Kanazawa I, Kawabata M, Mouradian MM, Okazawa H.
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| Hum Mol Genet 8(6):977-87.
1999
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19 | POU3F2, POU3F3
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| The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U.
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| Malik KF, Jaffe H, Brady J, Young WS 3rd.
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| Brain Res Mol Brain Res 45(1):99-107. 1997
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20 | POU3F2
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| Isolation of the human genomic brain-2/N-Oct 3 gene (POUF3) and assignment to chromosome 6q16.
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| Atanasoski S, et al.
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| Genomics 26 : 272-280. 1995
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21 | POU3F2
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| The brn-2 gene regulates the melanocytic phenotype and tumorigenic potential of human melanoma cells.
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| Thomson JA, Murphy K, Baker E, Sutherland GR, Parsons PG, Sturm RA, Thomson F [corrected to Thomson JA].
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| Oncogene 11(4):691-700. 1995
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22 | POU3F2
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| cDNA cloning of human N-Oct 3, a nervous-system specific POU domain transcription factor binding to the octamer DNA motif.
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| Schreiber E, et al.
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| Nucleic Acids Res 21 : 253-258. 1993
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23 | CPHD1, POU2F1, POU2F2, POU3F2, POU3F4, POU4F1, POU5F1, POU5F1B, POU5F1P3, POU6F1
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| Chromosomal organization of mammalian POU domain factors.
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| Xia YR, et al.
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| Genomics 18 : 126-130. 1993
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24 | POU3F2
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| cDNA cloning of human N-Oct3, a nervous-system specific POU domain transcription factor binding to the octamer DNA motif.
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| Schreiber E, Tobler A, Malipiero U, Schaffner W, Fontana A.
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| Nucleic Acids Res. 21(2):253-8. 1993
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