1 | PARK7, PON2
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| DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress.
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| Parsanejad M, Bourquard N, Qu D, Zhang Y, Huang E, Rousseaux MW, Aleyasin H, Irrcher I, Callaghan S, Vaillant DC, Kim RH, Slack RS, Mak TW, Reddy ST, Figeys D, Park DS.
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| PLoS One 9(9):e106601. doi: 10.1371/journal.pone.0106601. eCollection 2014.
2014
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2 | PON1, PON2, PON3
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| Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease.
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| Erlich PM, Lunetta KL, Cupples LA, Abraham CR, Green RC, Baldwin CT, Farrer LA.
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| Neurobiol Aging eurobiol Aging. 2010 Oct 25. [Epub ahead of print]PMID: 20980077 2010
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3 | PON1, PON2
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| Paraoxonase gene polymorphisms and stroke severity.
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| Lazaros L, Markoula S, Kyritsis A, Georgiou I.
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| Eur J Neurol ur J Neurol. 2009 Nov 23. [Epub ahead of print]PMID: 19930448 2009
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4 | PON2
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| A common mutation in paraoxonase-2 results in impaired lactonase activity.
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| Stoltz DA, Ozer EA, Recker TJ, Estin M, Yang X, Shih DM, Lusis AJ, Zabner J.
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| J Biol Chem 284(51):35564-71. Epub .PMID: 19840942 2009
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5 | PON2
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| Paraoxonase2 C311S polymorphism and low levels of HDL contribute to a higher mortality risk after acute myocardial infarction in elderly patients.
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| Marchegiani F, Spazzafumo L, Provinciali M, Cardelli M, Olivieri F, Franceschi C, Lattanzio F, Antonicelli R.
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| Mol Genet Metab 98(3):314-8. Epub 2009 May 27.PMID: 19540141 2009
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6 | PON2
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| Paraoxonase 2 attenuates macrophage triglyceride accumulation via inhibition of diacylglycerol acyltransferase 1.
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| Rosenblat M, Coleman R, Reddy ST, Aviram M.
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| J Lipid Res 50(5):870-9. Epub 2008 Dec 16.PMID: 19091699 2009
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7 | PON1, PON2
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| The roles of PON1 and PON2 in cardiovascular disease and innate immunity.
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| Shih DM, Lusis AJ.
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| Curr Opin Lipidol 20(4):288-92. Review.PMID: 19474728 2009
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8 | PON2
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| Decreased paraoxonase-2 expression in human carotids during the progression of atherosclerosis.
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| Fortunato G, Di Taranto MD, Bracale UM, Del Guercio L, Carbone F, Mazzaccara C, Morgante A, D'Armiento FP, D'Armiento M, Porcellini M, Sacchetti L, Bracale G, Salvatore F.
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| Arterioscler Thromb Vasc Biol 28(3):594-600. Epub 2008 Feb 7.PMID: 18258817 2008
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9 | PON2
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| Macrophage paraoxonase 2 (PON2) expression is upregulated by unesterified cholesterol through activation of the phosphatidylinositol 3-kinase (PI3K) pathway.
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| Shiner M, Fuhrman B, Aviram M.
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| Biol Chem 388(12):1353-8.PMID: 18020951 2007
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10 | PON2
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| Biological role, protein expression, subcellular localization, and oxidative stress response of paraoxonase 2 in the intestine of humans and rats.
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| Levy E, Trudel K, Bendayan M, Seidman E, Delvin E, Elchebly M, Lavoie JC, Precourt LP, Amre D, Sinnett D.
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| Am J Physiol Gastrointest Liver Physiol 293(6):G1252-61. Epub 2007 Oct 4.PMID: 17916643 2007
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11 | PON1, PON2, PON3
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| Polymorphisms in the PON gene cluster are associated with Alzheimer disease.
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| Erlich PM, Lunetta KL, Cupples LA, Huyck M, Green RC, Baldwin CT, Farrer LA; MIRAGE Study Group.
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| Hum Mol Genet 15(1):77-85. Epub 2005 Nov 30. 2006
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12 | PON1, PON2, PON3
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| Human paraoxonase gene cluster polymorphisms as predictors of coronary heart disease risk in the prospective Northwick Park Heart Study II.
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| Robertson KS, Hawe E, Miller GJ, Talmud PJ, Humphries SE; Northwick Park Heart Study II.
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| Biochim Biophys Acta 1639(3):203-12. 2003
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13 | PON2
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| Paraoxonase2 polymorphisms are associated with nephropathy in Type II diabetes.
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| Pinizzotto M, Castillo E, Fiaux M, Temler E, Gaillard RC, Ruiz J.
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| Diabetologia 44(1):104-7. 2001
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14 | PON1, PON2
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| DNA polymorphisms in two paraoxonase genes (PON1 and PON2) are associated with the risk of coronary heart disease.
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| Sanghera DK, Aston CE, Saha N, Kamboh MI.
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| Am J Hum Genet 62(1):36-44. 1998
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15 | PON2
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| Human PON2 gene at 7q21.3 : cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence.
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| Mochizuki H, et al.
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| Gene 213 : 149-157. 1998
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16 | PON1, PON2, PON3
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| The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family.
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| Primo-Parmo SL, et al.
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| Genomics 33 : 498-507. 1996
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