Citations for
1CHTF18, POLE, RFC1
Human CTF18-RFC clamp-loader complexed with non-synthesising DNA polymerase ε efficiently loads the PCNA sliding clamp.
Fujisawa R, Ohashi E, Hirota K, Tsurimoto T.
Nucleic Acids Res 45(8):4550-4563. doi: 10.1093/nar/gkx096. 2017
2CHTF18, CHTF8, POLE, RFC1
A conserved Polϵ binding module in Ctf18-RFC is required for S-phase checkpoint activation downstream of Mec1.
García-Rodríguez LJ, De Piccoli G, Marchesi V, Jones RC, Edmondson RD, Labib K.
Nucleic Acids Res 43(18):8830-8. doi: 10.1093/nar/gkv799. Epub 2015 Aug 6. 2015
3POLD1, POLE
Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas.
Palles C, Cazier JB, Howarth KM, Domingo E, Jones AM, Broderick P, Kemp Z, Spain SL, Guarino E, Salguero I, Sherborne A, Chubb D, Carvajal-Carmona LG, Ma Y, Kaur K, Dobbins S, Barclay E, Gorman M, Martin L, Kovac MB, Humphray S; CORGI Consortium; WGS500 Consortium, Lucassen A, Holmes CC, Bentley D, Donnelly P, Taylor J, Petridis C, Roylance R, Sawyer EJ, Kerr DJ, Clark S, Grimes J, Kearsey SE, Thomas HJ, McVean G, Houlston RS, Tomlinson I.
Nat Genet 45(2):136-44. doi: 10.1038/ng.2503. Epub 2012 Dec 23. Erratum in: Nat Genet. 2013 Jun;45(6):713. Guarino Almeida, Estrella [corr 2013
4FILS, POLE
Polymerase ε1 mutation in a human syndrome with facial dysmorphism, immunodeficiency, livedo, and short stature ("FILS syndrome").
Pachlopnik Schmid J, Lemoine R, Nehme N, Cormier-Daire V, Revy P, Debeurme F, Debré M, Nitschke P, Bole-Feysot C, Legeai-Mallet L, Lim A, de Villartay JP, Picard C, Durandy A, Fischer A, de Saint Basile G.
J Exp Med 209(13):2323-30. doi: 10.1084/jem.20121303. Epub 2012 Dec 10. 2012
5POLE
Human DNA polymerase ε is able to efficiently extend from multiple consecutive ribonucleotides.
Göksenin AY, Zahurancik W, LeCompte KG, Taggart DJ, Suo Z, Pursell ZF.
J Biol Chem 287(51):42675-84. doi: 10.1074/jbc.M112.422733. Epub 2012 Oct 23. 2012
6POLE, PXMP2
The Pxmp2 and PoleI genes are linked by a bidirectional promoter in an evolutionary conserved fashion.
Otte DM, Schwaab U, Luers GH.
Gene 313:119-26. 2003
7PCNA, POLE
Human DNA polymerase epsilon colocalizes with proliferating cell nuclear antigen and DNA replication late, but not early, in S phase.
Fuss J, Linn S.
J Biol Chem 277(10):8658-66. 2002
8MDM2, POLE
MDM2 interacts with the C-terminus of the catalytic subunit of DNA polymerase epsilon.
Vlatkovic N, Guerrera S, Li Y, Linn S, Haines DS, Boyd MT.
Nucleic Acids Res 28(18):3581-6. 2000
9POLE
Structural organization and splice variants of the POLE1 gene encoding the catalytic subunit of human DNA polymerase epsilon.
Huang D, et al.
Biochem J 339 ( Pt 3):657-65. 1999
10GADD45A, FEN1, PCNA, POLD1, POLE, RFC1
Proliferating cell nuclear antigen : more than a clamp for DNA polymerases.
Jonsson ZO, Hubscher U.
BioEssays 19(11):967-75. 1997
11POLE
Localization of the gene for DNA polymerase epsilon (POLE) to human chromosome 12q24.3 and rat chromosome 12 by somatic cell hybrid panels and fluorescence in situ hybridization.
Szpirer J, et al.
Genomics 20 : 223-226. 1994
12POLE
Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase epsilon.
Kesti T, et al.
J Biol Chem 268 : 10238-10245. 1993