Citations for
1ABL1, HIPK2, PML
The Tyrosine Kinase c-Abl Promotes Homeodomain-interacting Protein Kinase 2 (HIPK2) Accumulation and Activation in Response to DNA Damage.
Reuven N, Adler J, Porat Z, Polonio-Vallon T, Hofmann TG, Shaul Y.
J Biol Chem 290(27):16478-88. doi: 10.1074/jbc.M114.628982. Epub 2015 May 5. 2015
2NACC1, PML
Nucleus accumbens associated 1 is recruited within the promyelocytic leukemia nuclear body through SUMO modification.
Tatemichi Y, Shibazaki M, Yasuhira S, Kasai S, Tada H, Oikawa H, Suzuki Y, Takikawa Y, Masuda T, Maesawa C.
Cancer Sci 106(7):848-56. doi: 10.1111/cas.12680. 2015
3KAT6A, PML, TP53
MOZ increases p53 acetylation and premature senescence through its complex formation with PML.
Rokudai S, Laptenko O, Arnal SM, Taya Y, Kitabayashi I, Prives C.
Proc Natl Acad Sci U S A 110(10):3895-900. doi: 10.1073/pnas.1300490110. Epub 2013 Feb 19. 2013
4PML
PML promotes MHC class II gene expression by stabilizing the class II transactivator.
Ulbricht T, Alzrigat M, Horch A, Reuter N, von Mikecz A, Steimle V, Schmitt E, Krämer OH, Stamminger T, Hemmerich P.
J Cell Biol 199(1):49-63. doi: 10.1083/jcb.201112015. Epub 2012 Sep 24. 2012
5PML, UHRF1
The epigenetic regulator UHRF1 promotes ubiquitination-mediated degradation of the tumor-suppressor protein promyelocytic leukemia protein.
Guan D, Factor D, Liu Y, Wang Z, Kao HY.
Oncogene ncogene. 2012 Sep 3. doi: 10.1038/onc.2012.406. [Epub ahead of print] 2012
6PML
A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance.
Ito K, Carracedo A, Weiss D, Arai F, Ala U, Avigan DE, Schafer ZT, Evans RM, Suda T, Lee CH, Pandolfi PP.
Nat Med 18(9):1350-8. 2012
7ITGB1, PML
Promyelocytic leukemia protein (PML) regulates endothelial cell network formation and migration in response to tumor necrosis factor α (TNFα) and interferon α (IFNα).
Cheng X, Liu Y, Chu H, Kao HY.
J Biol Chem 287(28):23356-67. doi: 10.1074/jbc.M112.340505. Epub 2012 May 15. 2012
8PML
The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA.
Rabellino A, Carter B, Konstantinidou G, Wu SY, Rimessi A, Byers LA, Heymach JV, Girard L, Chiang CM, Teruya-Feldstein J, Scaglioni PP.
Cancer Res 72(9):2275-84. doi: 10.1158/0008-5472.CAN-11-3159. Epub 2012 Mar 9. 2012
9PER2, PML
PML regulates PER2 nuclear localization and circadian function.
Miki T, Xu Z, Chen-Goodspeed M, Liu M, Van Oort-Jansen A, Rea MA, Zhao Z, Lee CC, Chang KS.
EMBO J 31(6):1427-39. doi: 10.1038/emboj.2012.1. Epub 2012 Jan 24. 2012
10PML
Role of the promyelocytic leukaemia protein in cell death regulation.
Salomoni P, Dvorkina M, Michod D.
Cell Death Dis 3:e247. doi: 10.1038/cddis.2011.122. Review. 2012
11PML, TBX2
Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence.
Martin N, Benhamed M, Nacerddine K, Demarque MD, van Lohuizen M, Dejean A, Bischof O.
EMBO J 31(1):95-109. doi: 10.1038/emboj.2011.370. Epub 2011 Oct 14. 2012
12CIITA, PML
PML promotes MHC class II gene expression by stabilizing the class II transactivator.
Ulbricht T, Alzrigat M, Horch A, Reuter N, von Mikecz A, Steimle V, Schmitt E, Krämer OH, Stamminger T, Hemmerich P.
J Cell Biol 199(1):49-63. doi: 10.1083/jcb.201112015. Epub 2012 Sep 24. 2012
13GNL3, PML, TERF1
Nucleostemin prevents telomere damage by promoting PML-IV recruitment to SUMOylated TRF1.
Hsu JK, Lin T, Tsai RY.
J Cell Biol 197(5):613-24. doi: 10.1083/jcb.201109038. 2012
14AXIN1, PML, TP53
AXIN is an essential co-activator for the promyelocytic leukemia protein in p53 activation.
Li Q, He Y, Wei L, Wu X, Wu D, Lin S, Wang Z, Ye Z, Lin SC.
Oncogene 30(10):1194-204. Epub 2010 Nov 8. 2011
15NUP205, PML, RIN3, TM7SF4
Genome-wide association identifies three new susceptibility loci for Paget's disease of bone.
Albagha OM, Wani SE, Visconti MR, Alonso N, Goodman K, Brandi ML, Cundy T, Chung PY, Dargie R, Devogelaer JP, Falchetti A, Fraser WD, Gennari L, Gianfrancesco F, Hooper MJ, Van Hul W, Isaia G, Nicholson GC, Nuti R, Papapoulos S, Montes Jdel P, Ratajczak T, Rea SL, Rendina D, Gonzalez-Sarmiento R, Di Stefano M, Ward LC, Walsh JP, Ralston SH; Genetic Determinants of Paget's Disease (GDPD) Consortium.
Nat Genet 43(7):685-9. doi: 10.1038/ng.845. 2011
16PML
PML positively regulates interferon gamma signaling.
El Bougrini J, Dianoux L, Chelbi-Alix MK.
Biochimie 93(3):389-98. doi: 10.1016/j.biochi.2010.11.005. Epub 2010 Nov 27. 2011
17PML
PML is a key component for the differentiation of myeloid progenitor cells to macrophages.
Khalfin-Rabinovich Y, Weinstein A, Levi BZ.
Int Immunol 23(4):287-96. doi: 10.1093/intimm/dxr004. Epub 2011 Mar 22. 2011
18CFLAR, PML, RARA
PMLRARα binds to Fas and suppresses Fas-mediated apoptosis through recruiting c-FLIP in vivo.
Tao RH, Berkova Z, Wise JF, Rezaeian AH, Daniluk U, Ao X, Hawke DH, Karp JE, Lin HK, Molldrem JJ, Samaniego F.
Blood 118(11):3107-18. doi: 10.1182/blood-2011-04-349670. Epub 2011 Jul 29. 2011
19PML
PML regulates apoptosis at endoplasmic reticulum by modulating calcium release.
Giorgi C, Ito K, Lin HK, Santangelo C, Wieckowski MR, Lebiedzinska M, Bononi A, Bonora M, Duszynski J, Bernardi R, Rizzuto R, Tacchetti C, Pinton P, Pandolfi PP.
Science 330(6008):1247-51. Epub 2010 Oct 28. 2010
20HIPK2, PML
PML tumor suppressor is regulated by HIPK2-mediated phosphorylation in response to DNA damage.
Gresko E, Ritterhoff S, Sevilla-Perez J, Roscic A, Fröbius K, Kotevic I, Vichalkovski A, Hess D, Hemmings BA, Schmitz ML.
Oncogene 28(5):698-708. Epub 2008 Nov 17. 2009
21PML, UBE3A
E6AP promotes the degradation of the PML tumor suppressor.
Louria-Hayon I, Alsheich-Bartok O, Levav-Cohen Y, Silberman I, Berger M, Grossman T, Matentzoglu K, Jiang YH, Muller S, Scheffner M, Haupt S, Haupt Y.
Cell Death Differ 16(8):1156-66. Epub 2009 Mar 27. 2009
22PML
The tumor suppressor Pml regulates cell fate in the developing neocortex.
Regad T, Bellodi C, Nicotera P, Salomoni P.
Nat Neurosci. 12(2):132-40 2009
23PML, RARA
PML-RARalpha initiates leukemia by conferring properties of self-renewal to committed promyelocytic progenitors.
Wojiski S, Guibal FC, Kindler T, Lee BH, Jesneck JL, Fabian A, Tenen DG, Gilliland DG.
Leukemia 23(8):1462-71. Epub 2009 Mar 26.PMID: 19322209 2009
24FMF, MEFV, MID1, MID2, PML, TRIM10, TRIM11, TRIM13, TRIM15, TRIM17, TRIM2, TRIM21, TRIM22, TRIM23, TRIM24, TRIM25, TRIM26, TRIM27, TRIM28, TRIM3, TRIM31, TRIM32, TRIM33, TRIM34, TRIM35, TRIM36, TRIM37, TRIM38, TRIM39, TRIM4, TRIM40, TRIM41, TRIM42, TRIM43, TRIM45, TRIM46, TRIM47, TRIM48, TRIM49, TRIM5, TRIM50, TRIM52, TRIM53, TRIM54, TRIM55, TRIM56, TRIM58, TRIM59, TRIM6, TRIM60, TRIM61, TRIM62, TRIM63, TRIM64, TRIM65, TRIM67, TRIM68, TRIM69, TRIM7, TRIM71, TRIM72, TRIM73, TRIM74, TRIM75, TRIM8, TRIM9, TRIML1
TRIM family proteins and their emerging roles in innate immunity.
Ozato K, Shin DM, Chang TH, Morse HC 3rd.
Nat Rev Immunol 8(11):849-60. Review. 2008
25EP300, HIPK2, PML
PML activates transcription by protecting HIPK2 and p300 from SCFFbx3-mediated degradation.
Shima Y, Shima T, Chiba T, Irimura T, Pandolfi PP, Kitabayashi I.
Mol Cell Biol 28(23):7126-38. Epub 2008 Sep 22. 2008
26HDAC7, PML
Histone deacetylase 7 promotes PML sumoylation and is essential for PML nuclear body formation.
Gao C, Ho CC, Reineke E, Lam M, Cheng X, Stanya KJ, Liu Y, Chakraborty S, Shih HM, Kao HY.
Mol Cell Biol 28(18):5658-67. Epub 2008 Jul 14. 2008
27JAK2, MPD, PML, PRV
Essential thrombocythemia, polycythemia vera, and myelofibrosis: current management and the prospect of targeted therapy.
Tefferi A.
Am J Hematol 83(6):491-7. Review. 2008
28PML, RARA
Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation.
Nasr R, Guillemin MC, Ferhi O, Soilihi H, Peres L, Berthier C, Rousselot P, Robledo-Sarmiento M, Lallemand-Breitenbach V, Gourmel B, Vitoux D, Pandolfi PP, Rochette-Egly C, Zhu J, de Thé H.
Nat Med 14(12):1333-42. Epub 2008 Nov 23. Erratum in: Nat Med. 2009 Jan;15(1):117. PMID: 19029980 2008
29CSNK1A1, PML
PML enhances the regulation of p53 by CK1 in response to DNA damage.
Alsheich-Bartok O, Haupt S, Alkalay-Snir I, Saito S, Appella E, Haupt Y.
Oncogene 27(26):3653-61. Epub 2008 Feb 4. 2008
30PML, SATB1
Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus.
Kumar PP, Bischof O, Purbey PK, Notani D, Urlaub H, Dejean A, Galande S.
Nat Cell Biol 9(1):45-56. Epub 2006 Dec 17. 2007
31ETV6, FOXP1, PAX5, PML, ZNF521
Identification of PML as novel PAX5 fusion partner in childhood acute lymphoblastic leukaemia.
Nebral K, König M, Harder L, Siebert R, Haas OA, Strehl S.
Br J Haematol 139(2):269-74. 2007
32PML, RARA
Identification of PML-RARA rearrangement by RT-PCR and sequencing in an acute promyelocytic leukemia without t(15;17) on G-banding and FISH.
Han JY, Kim KE, Kim KH, Park JI, Kim JS.
Leuk Res 31(2):239-43. Epub 2006 Jun 21.PMID: 16797070 2007
33PML, CSNK2A1
A CK2-dependent mechanism for degradation of the PML tumor suppressor.
Scaglioni PP, Yung TM, Cai LF, Erdjument-Bromage H, Kaufman AJ, Singh B, Teruya-Feldstein J, Tempst P, Pandolfi PP.
Cell 126(2):269-83. 2006
34HIF1A, MTOR, PML
PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR.
Bernardi R, Guernah I, Jin D, Grisendi S, Alimonti A, Teruya-Feldstein J, Cordon-Cardo C, Simon MC, Rafii S, Pandolfi PP.
Nature 442(7104):779-85. 2006
35PML, RARA
PML-RARalpha fusion gene transcripts and biological features in acute promyelocytic leukemia patients.
Melo RA, de Vasconcellos JF, Melo FC, Machado CG, Lacerda TM, Souto FR.
Clin Lab Haematol 28(2):126-9.PMID: 16630218 2006
36PML
A role for PML3 in centrosome duplication and genome stability.
Xu ZX, Zou WX, Lin P, Chang KS.
Mol Cell. 17(5):721-32 2005
37PML
PML interacts with Myc, and Myc target gene expression is altered in PML-null fibroblasts.
Cairo S, De Falco F, Pizzo M, Salomoni P, Pandolfi PP, Meroni G.
Oncogene 24(13):2195-203 2005
38PML
Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein.
Takahashi H, Hatakeyama S, Saitoh H, Nakayama KI.
J Biol Chem. 280(7):5611-21 2005
39PML
Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia.
Gurrieri C, Nafa K, Merghoub T, Bernardi R, Capodieci P, Biondi A, Nimer S, Douer D, Cordon-Cardo C, Gallagher R, Pandolfi PP.
Blood 103(6):2358-62. Epub 2003 Nov 20. 2004
40MAPK11, PML
Promyelocytic leukemia is a direct inhibitor of SAPK2/p38 mitogen-activated protein kinase.
Shin J, Park B, Cho S, Lee S, Kim Y, Lee SO, Cho K, Lee S, Jin BS, Ahn JH, Choi EJ, Ahn K.
J Biol Chem 279(39):40994-1003. Epub 2004 Jul 23. 2004
41MDM2, PML
PML regulates p53 stability by sequestering Mdm2 to the nucleolus.
Bernardi R, Scaglioni PP, Bergmann S, Horn HF, Vousden KH, Pandolfi PP.
Nat Cell Biol. 6(7):665-72 2004
42PML
Cytoplasmic PML function in TGF-beta signalling.
Lin HK, Bergmann S, Pandolfi PP.
Nature 431(7005):205-11 2004
43PML
PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein.
Daniels MJ, Marson A, Venkitaraman AR.
Nat Struct Mol Biol. 11(11):1114-21 2004
44PML
c-Myb associates with PML in nuclear bodies in hematopoietic cells.
Dahle Ø, Bakke O, Gabrielsen OS.
Exp Cell Res. 297(1):118-26 2004
45PML
The Ankrd2 protein, a link between the sarcomere and the nucleus in skeletal muscle.
Kojic S, Medeot E, Guccione E, Krmac H, Zara I, Martinelli V, Valle G, Faulkner G.
J Mol Biol. 339(2):313-25 2004
46PAWR, PML, THAP1
THAP1 is a nuclear proapoptotic factor that links prostate-apoptosis-response-4 (Par-4) to PML nuclear bodies.
Roussigne M, Cayrol C, Clouaire T, Amalric F, Girard JP.
Oncogene 22(16):2432-42. 2003
47PML, TRIM69
Forced expression of RNF36 induces cell apoptosis.
Shyu HW, Hsu SH, Hsieh-Li HM, Li H.
Exp Cell Res 287(2):301-13. 2003
48PML
Recruitment of human cyclin T1 to nuclear bodies through direct interaction with the PML protein.
Marcello A, Ferrari A, Pellegrini V, Pegoraro G, Lusic M, Beltram F, Giacca M.
EMBO J. 22(9):2156-66 2003
49PML
Physical and functional interactions between PML and MDM2
Wei X, Yu ZK, Ramalingam A, Grossman SR, Yu JH, Bloch DB, Maki CG.
J Biol Chem. 278(31):29288-97 2003
50PML
Promyelocytic leukemia protein sensitizes tumor necrosis factor alpha-induced apoptosis by inhibiting the NF-kappaB survival pathway.
Wu WS, Xu ZX, Hittelman WN, Salomoni P, Pandolfi PP, Chang KS.
J Biol Chem. 278(14):12294-304 2003
51PML
PML-nuclear bodies are involved in cellular serum response.
Matsuzaki K, Minami T, Tojo M, Honda Y, Saitoh N, Nagahiro S, Saya H, Nakao M.
Genes Cells. 8(3):275-86 2003
52PML
Opposing effects of PML and PML/RAR alpha on STAT3 activity.
Kawasaki A, Matsumura I, Kataoka Y, Takigawa E, Nakajima K, Kanakura Y.
Blood 101(9):3668-73 2003
53PML
PML colocalizes with and stabilizes the DNA damage response protein TopBP1.
Xu ZX, Timanova-Atanasova A, Zhao RX, Chang KS.
Mol Cell Biol. 23(12):4247-56 2003
54PML
PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemia.
Padua RA, Larghero J, Robin M, le Pogam C, Schlageter MH, Muszlak S, Fric J, West R, Rousselot P, Phan TH, Mudde L, Teisserenc H, Carpentier AF, Kogan S, Degos L, Pla M, Bishop JM, Stevenson F, Charron D, Chomienne C.
Nat Med. 9(11):1413-7 2003
55PML
The role of PML in tumor suppression.
Salomoni P, Pandolfi PP.
Cell 108(2):165-70. Review. 2002
56NR4A1, PML
Promyelocytic leukemia protein PML inhibits Nur77-mediated transcription through specific functional interactions.
Wu WS, Xu ZX, Ran R, Meng F, Chang KS.
Oncogene 21(24):3925-33. 2002
57PML
PML mediates the interferon-induced antiviral state against a complex retrovirus via its association with the viral transactivator.
Regad T, Saib A, Lallemand-Breitenbach V, Pandolfi PP, de The H, Chelbi-Alix MK.
EMBO J 20(13):3495-505. 2001
58PML
PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA.
Cohen N, Sharma M, Kentsis A, Perez JM, Strudwick S, Borden KL.
EMBO J. 20(16):4547-59 2001
59HDAC1, HDAC2, PML
The growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylases.
Wu WS, Vallian S, Seto E, Yang WM, Edmondson D, Roth S, Chang KS.
Mol Cell Biol. 21(7):2259-68 2001
60PML, SKI
Role of PML and PML-RARalpha in Mad-mediated transcriptional repression.
Khan MM, Nomura T, Kim H, Kaul SC, Wadhwa R, Shinagawa T, Ichikawa-Iwata E, Zhong S, Pandolfi PP, Ishii S.
Mol Cell. 7(6):1233-43 2001
61PML
The function of PML in p53-dependent apoptosis.
Guo A, Salomoni P, Luo J, Shih A, Zhong S, Gu W, Pandolfi PP.
Nat Cell Biol. 2(10):730-6 2000
62PML
Two new 3' PML breakpoints in t(15;17)(q22;q21)-positive acute promyelocytic leukemia.
Chillon MC, Gonzalez M, Garcia-Sanz R, Balanzategui A, Gonzalez D, Lopez-Perez R, Mateos MV, Alaejos I, Rayon C, Arbeteta J, Hernandez JM, Orfao A, San Miguel J.
Genes Chromosomes Cancer 27(1):35-43 2000
63LOXL1, PML, STOML1
Physical linkage of the lysyl oxidase-like (LOXL1) gene to the PML gene on human chromosome 15q22.
Goy A, Gilles F, Remache Y, Zelenetz AD.
Cytogenet Cell Genet 88(1-2):22-4. 2000
64GOLGA6, GOLGA2, GOLGA3, GOLGA4, GOLGB1, PML
Cloning and characterization of a Golgin-related gene from the large-scale polymorphism linked to the PML gene.
Gilles F, Goy A, Remache Y, Manova K, Zelenetz AD.
Genomics 70(3):364-74. 2000
65PML
Sequestration and inhibition of Daxx-mediated transcriptional repression by PML.
Li H, Leo C, Zhu J, Wu X, O'Neil J, Park EJ, Chen JD.
Mol Cell Biol. 20(5):1784-96 2000
66PML
Potentiation of GATA-2 activity through interactions with the promyelocytic leukemia protein (PML) and the t(15;17)-generated PML-retinoic acid receptor alpha oncoprotein.
Tsuzuki S, Towatari M, Saito H, Enver T.
Mol Cell Biol. 20(17):6276-86 2000
67PML
PML regulates p53 acetylation and premature senescence induced by oncogenic Ras.
Pearson, M.; Carbone, R.; Sebastiani, C.; Cioce, M.; Fagioli, M.; Saito, S.; Higashimoto, Y.; Appella, E.; Minucci, S.; Pandolfi, P. P.; Pelicci, P. G.
Nature 406: 207-210 2000
68CREBBP, PML
Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling.
Doucas V, et al.
Proc Natl Acad Sci U S A 96(6):2627-2632. 1999
69ANXA2, PML
Annexin II and bleeding in acute promyelocytic leukemia.
Menell JS, et al.
N Engl J Med 340(13):994-1004. 1999
70PML
Expression and role of PML gene in normal adult hematopoiesis: functional interaction between PML and Rb proteins in erythropoiesis.
Labbaye C, et al.
Oncogene 18(23):3529-40. 1999
71DAXX, PML
Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs).
Torii S, et al.
EMBO J 18(21):6037-6049 1999
72ALK, PML, RARA
Identification of novel chromosomal rearrangements in acute myelogenous leukemia involving loci on chromosome 2p23, 15q22 and 17q21.
Melnick A, Fruchtman S, Zelent A, Liu M, Huang Q, Boczkowska B, Calasanz M, Fernandez A, Licht JD, Najfeld V.
Leukemia 13(10):1534-8. 1999
73BRAF, TRIM24, PML
A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteins.
Zhong S, Delva L, Rachez C, Cenciarelli C, Gandini D, Zhang H, Kalantry S, Freedman LP, Pandolfi PP.
Nat Genet 23(3):287-95. 1999
74PML
The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH: a RING may link hematopoiesis and growth control.
Topcu Z, Mack DL, Hromas RA, Borden KL.
Oncogene. 18(50):7091-100 1999
75PML, RARA, ZBTB16
Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.
He LZ, Guidez F, Tribioli C, Peruzzi D, Ruthardt M, Zelent A, Pandolfi PP.
Nat Genet 18(2):126-35. 1998
76PML, RARA, ZBTB16
Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia.
Grignani F, De Matteis S, Nervi C, Tomassoni L, Gelmetti V, Cioce M, Fanelli M, Ruthardt M, Ferrara FF, Zamir I, Seiser C, Grignani F, Lazar MA, Minucci S, Pelicci PG.
Nature 391(6669):815-8. 1998
77HDAC1, HDAC2, PML, RARA, ZBTB16
Role of the histone deacetylase complex in acute promyelocytic leukaemia.
Lin RJ, et al.
Nature 391 : 811-814. 1998
78PML
PML induces a novel caspase-independent death process.
Quignon F, et al.
Nat Genet 20 : 259-265. 1998
79PML
Pml is essential for multiple apoptotic pathways.
Wang ZG, et al.
Nat Genet 20 : 266-272. 1998
80PML
Proto-oncogene PML controls genes devoted to MHC class I antigen presentation.
Zheng P, et al.
Nature 396 : 373-376. 1998
81CREBBP, PML
Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body.
LaMorte VJ, et al.
Proc Natl Acad Sci U S A 95(9):4991-6. 1998
82PML, SP100
Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment.
Seeler JS, et al.
Proc Natl Acad Sci U S A 95(13):7316-21. 1998
83PML, SUMO1
Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus.
Muller S, et al.
EMBO J 17(1):61-70. 1998
84PML
Modulation of Fos-mediated AP-1 transcription by the promyelocytic leukemia protein.
Vallian S, Gäken JA, Gingold EB, Kouzarides T, Chang KS, Farzaneh F.
Oncogene 16(22):2843-53 1998
85PML, RBP1
The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein.
Alcalay M, Tomassoni L, Colombo E, Stoldt S, Grignani F, Fagioli M, Szekely L, Helin K, Pelicci PG.
Mol Cell Biol. 18(2):1084-93 1998
86PML
The promyelocytic leukemia protein interacts with Sp1 and inhibits its transactivation of the epidermal growth factor receptor promoter.
Vallian S, Chin KV, Chang KS.
Mol Cell Biol. 18(12):7147-56 1998
87PML
Ret finger protein is a normal component of PML nuclear bodies and interacts directly with PML.
Cao T, Duprez E, Borden KL, Freemont PS, Etkin LD.
J Cell Sci. 111 ( Pt 10):1319-29 1998
88PML, RARA
A retinoid-resistant acute promyelocytic leukemia subclone expresses a dominant negative PML-RARalpha mutation.
Shao W, Benedetti L, Lamph WW, Nervi C, Miller WH Jr.
Blood 89(12):4282-9. 1997
89PML, SUMO1
Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1.
Sternsdorf T, et al.
J Cell Biol 139(7):1621-34. 1997
90PML
Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies.
Koken MH, Reid A, Quignon F, Chelbi-Alix MK, Davies JM, Kabarowski JH, Zhu J, Dong S, Chen S, Chen Z, Tan CC, Licht J, Waxman S, de Thé H, Zelent A.
Proc Natl Acad Sci U S A. 94(19):10255-60 1997
91PML
A PMLRARalpha transgene initiates murine acute promyelocytic leukemia.
Brown D, Kogan S, Lagasse E, Weissman I, Alcalay M, Pelicci PG, Atwater S, Bishop JM.
Proc Natl Acad Sci U S A. 94(6):2551-6 1997
92PML, SUMO1
PIC 1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia.
Boddy MN, Howe K, Etkin LD, Solomon E, Freemont PS
Oncogene. 13(5):971-82 1996
93PML
Transcriptional induction of the PML growth suppressor gene by interferons is mediated through an ISRE and a GAS element.
Stadler M, et al.
Oncogene 11 : 2565-2573. 1995
94GOLGA6, PML
The PML gene is linked to a megabase-scale insertion/deletion restriction fragment length polymorphism.
Goy A, et al.
Genomics 26 : 327-333. 1995
95PML, RARA
Analysis of the joining sequences of the t(15;17) translocation in human acute promyelocytic leukemia : sequence non-specific recombination between the PML and RARA genes within identical short stretches.
Yoshida H, et al.
Genes Chromosomes Cancer 12 : 37-44. 1995
96PML, RARA
Molecular analysis of simple variant translocations in acute promyelocytic leukemia.
Borrow J, et al.
Genes Chromosomes Cancer 9 : 234-243. 1994
97PML
Breakpoint clusters of the PML gene in acute promyelocytic leukemia : primary structure of the reciprocal products of the PML-RARA gene in a patient with t(15;17).
Dong S, et al.
Genes Chromosomes Cancer 6 : 133-139. 1993
98PML, RARA
The PML-retinoic acid receptor alpha translocation converts the receptor from an inhibitor to a retinoic acid-dependent activator of transcription factor AP-1.
Doucas V, et al.
Proc Natl Acad Sci U S A 90 : 9345-9349. 1993
99HYKPP, PML, SCN4A
Molecular genetic and genetic correlations in sodium channelopathies : lack of founder effect and evidence for a second gene.
Wang J, et al.
Am J Hum Genet 52 : 1074-1084. 1993
100PML, RARA
Delineation of translocation t(15;17) in acute promyelocytic leukemia by chromosomal in situ suppression hybridization.
Speicher MR, et al.
Leuk Res 17 : 359-364. 1993
101PML
Rearrangements of the RARA and PML genes in a cytogenetic variant of acute promyelocytic leukemia.
Baranger L, et al.
Genes Chromosomes Cancer 6 : 118-120. 1993
102PML
The t(15;17) breakpoint in acute promyelocytic leukemia cluster within two different sites of the myl gene : targets for the detection of minimal residual disease by the polymerase chain reaction.
Chang KS, et al.
Blood 79 : 554-558. 1992
103PML
Structure, localization, and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL) : structural similarities with a new family of oncoproteins.
Kastner P, et al.
EMBO J 11 : 629-642. 1992
104RARA, PML
Characterization of a fusion cDNA (RARA/myl) transcribed from the t(15;17) translocation breakpoint in acute promyelocytic leukemia.
Chang KS, et al.
Mol Cell Biol 12 : 800-810. 1992
105PML
Molecular rearrangements of the MYL gene in acute promyelocytic leukemia (APL,M3) define a breakpoint cluster region as well as some molecular variants.
Tong JH, et al.
Oncogene 7 : 311-316. 1992
106PML
Occurence of distinct PML-RAR-alpha fusion gene isoforms in patients with acute promyelocytic leukemia detected by reverse transcriptase/polymerase chain reaction.
Chen SJ, et al.
Oncogene 7 : 1223-1232. 1992
107PML
A PML/retinoic acid receptor alpha fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia.
Castaigne S, et al.
Blood 79 : 3110-3115. 1992
108PML
Identification of DNA rearrangements at the retinoic acid receptor-alpha (RAR-alpha) locus in all patients with acute promyelocytic leukemia (APL) and mapping of APL breakpoints within the RAR-alpha second intron.
Diverio D, et al.
Blood 79 : 3331-3336. 1992
109PML
Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia.
Pandolfi PP, et al.
EMBO J 11 : 1397-1407. 1992
110PML, RARA
Expression pattern of the RARalpha-PML fusion gene in acute promyelocytic leukemia.
Alcalay M, et al.
Proc Natl Acad Sci U S A 89 : 4840-4844. 1992
111PML, RARA
Molecular monitoring of the myl/retinoic acid receptor-alpha fusion gene in acute promyelocytic leukemia by polymerase chain reaction.
Biondi A, et al.
Blood 80 : 492-497. 1992
112RARA, PML
Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus.
Alcalay M, et al.
Proc Natl Acad Sci U S A 88 : 1977-1981. 1991
113PML
Characterization of a zinc finger gene disrupted by the t(15;17) in acute promyelocytic leukemia.
Goddard AD, et al.
Science 254 : 1371-1374. 1991
114PML
Structure and origin of acute promyelocytic leukemia myl/RARalpha cDNA and characterization of its retinoid-binding and transactivation properties.
Pandolfi PP, et al.
Oncogene 6 : 1285-1292. 1991
115PML, RARA
The T(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus.
ThŽ H de, et al.
Nature 347 : 558-561. 1990
116MIC7, PML, RARA
Genetic analysis of the 15;17 chromosome translocation associated with acute promyelocytic leukemia.
Sheer D, et al.
Proc Natl Acad Sci U S A 80 : 5007-5011. 1983