1 | EGRF, ERBB2, MET, PLXNB1, SEMA3C
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| SEMA3C drives cancer growth by transactivating multiple receptor tyrosine kinases via Plexin B1.
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| Peacock JW, Takeuchi A, Hayashi N, Liu L, Tam KJ, Al Nakouzi N, Khazamipour N, Tombe T, Dejima T, Lee KC, Shiota M, Thaper D, Lee WC, Hui DH, Kuruma H, Ivanova L, Yenki P, Jiao IZ, Khosravi S, Mui AL, Fazli L, Zoubeidi A, Daugaard M, Gleave ME, Ong CJ.
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| EMBO Mol Med 10(2):219-238. doi: 10.15252/emmm.201707689.
2018
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2 | PLXNB1, SEMA4D
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| The Semaphorin 4D-Plexin-B1-RhoA signaling axis recruits pericytes and regulates vascular permeability through endothelial production of PDGF-B and ANGPTL4.
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| Zhou H, Yang YH, Basile JR.
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| Angiogenesis 17(1):261-74. doi: 10.1007/s10456-013-9395-0. Epub 2013 Oct 10.
2014
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3 | PLXNB1, RAC1, RAC2, RAC3, RHOB, RND1, RND2, RND3
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| Interaction characteristics of Plexin-B1 with Rho family proteins.
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| Fansa EK, Dvorsky R, Zhang SC, Fiegen D, Ahmadian MR.
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| Biochem Biophys Res Commun 434(4):785-90. doi: 10.1016/j.bbrc.2013.04.012. Epub 2013 Apr 17.
2013
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4 | PLXNB1, SEMA4D
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| Does plexin-B1, a semaphorin 4D receptor, play a role in thrombosis?
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| Bird E, Smith PL, Seiffert D, Psaltis GC, Huang J, Schumacher WA.
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| Thromb Res 131(6):564-5. doi: 10.1016/j.thromres.2013.03.018. Epub 2013 Apr 30. No abstract available. 2013
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5 | MRAS, PLXNB1, RAPH1, SEMA4D
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| Semaphorin 4D/Plexin-B1-mediated M-Ras GAP activity regulates actin-based dendrite remodeling through Lamellipodin.
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| Tasaka G, Negishi M, Oinuma I.
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| J Neurosci 32(24):8293-305. doi: 10.1523/JNEUROSCI.0799-12.2012.
2012
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6 | PLXNB1, SEMA4D
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| Plexin-B1 and semaphorin 4D cooperate to promote perineural invasion in a RhoA/ROK-dependent manner.
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| Binmadi NO, Yang YH, Zhou H, Proia P, Lin YL, De Paula AM, Guimarães AL, Poswar FO, Sundararajan D, Basile JR.
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| Am J Pathol 180(3):1232-42. doi: 10.1016/j.ajpath.2011.12.009. Epub 2012 Jan 15.
2012
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7 | MET, PLXNB1, SEMA4D
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| Sema4D, the ligand for Plexin B1, suppresses c-Met activation and migration and promotes melanocyte survival and growth.
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| Soong J, Chen Y, Shustef EM, Scott GA.
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| J Invest Dermatol 132(4):1230-8. doi: 10.1038/jid.2011.414. Epub 2011 Dec 22.
2012
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8 | PLXNB1, SEMA4D
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| Plexin-B1 activates NF-κB and IL-8 to promote a pro-angiogenic response in endothelial cells.
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| Yang YH, Zhou H, Binmadi NO, Proia P, Basile JR.
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| PLoS One 6(10):e25826. doi: 10.1371/journal.pone.0025826. Epub 2011 Oct 18.
2011
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9 | PLXNB1, SEMA4D
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| Semaphorin 4D, a lymphocyte semaphorin, enhances tumor cell motility through binding its receptor, plexinB1, in pancreatic cancer.
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| Kato S, Kubota K, Shimamura T, Shinohara Y, Kobayashi N, Watanabe S, Yoneda M, Inamori M, Nakamura F, Ishiguro H, Nakaigawa N, Nagashima Y, Taguri M, Kubota Y, Goshima Y, Morita S, Endo I, Maeda S, Nakajima A, Nakagama H.
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| Cancer Sci 102(11):2029-37. doi: 10.1111/j.1349-7006.2011.02053.x. Epub 2011 Sep 13.
2011
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10 | PLXNB1
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| Plexin-B1 silencing inhibits ovarian cancer cell migration and invasion.
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| Ye S, Hao X, Zhou T, Wu M, Wei J, Wang Y, Zhou L, Jiang X, Ji L, Chen Y, You L, Zhang Y, Xu G, Zhou J, Ma D, Wang S.
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| BMC Cancer 10:611. doi: 10.1186/1471-2407-10-611.
2010
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11 | PLXNB1, SEMA4D
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| Roles of Sema4D and Plexin-B1 in tumor progression.
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| Ch'ng ES, Kumanogoh A.
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| Mol Cancer 9:251. doi: 10.1186/1476-4598-9-251. Review.
2010
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12 | PLXNB1, PTEN, SEMA4D
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| Semaphorin 4D/Plexin-B1 stimulates PTEN activity through R-Ras GTPase-activating protein activity, inducing growth cone collapse in hippocampal neurons.
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| Oinuma I, Ito Y, Katoh H, Negishi M.
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| J Biol Chem 285(36):28200-9. doi: 10.1074/jbc.M110.147546. Epub 2010 Jul 7.
2010
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13 | PLXNB1, SEMA4D
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| Roles of Sema4D-plexin-B1 interactions in the central nervous system for pathogenesis of experimental autoimmune encephalomyelitis.
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| Okuno T, Nakatsuji Y, Moriya M, Takamatsu H, Nojima S, Takegahara N, Toyofuku T, Nakagawa Y, Kang S, Friedel RH, Sakoda S, Kikutani H, Kumanogoh A.
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| J Immunol 184(3):1499-506. doi: 10.4049/jimmunol.0903302. Epub 2009 Dec 28.
2010
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14 | PLCG1, PLCG2, PLXNB1, SEMA4D
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| Semaphorin 4D signaling requires the recruitment of phospholipase C gamma into the plexin-B1 receptor complex.
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| Swiercz JM, Worzfeld T, Offermanns S.
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| Mol Cell Biol 29(23):6321-34. Epub 2009 Oct 5. 2009
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15 | PLXNB1
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| Plexin-B1 mutations in prostate cancer.
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| Wong OG, Nitkunan T, Oinuma I, Zhou C, Blanc V, Brown RS, Bott SR, Nariculam J, Box G, Munson P, Constantinou J, Feneley MR, Klocker H, Eccles SA, Negishi M, Freeman A, Masters JR, Williamson M.
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| Proc Natl Acad Sci U S A 104(48):19040-5. Epub 2007 Nov 16. 2007
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16 | PLXNB1, PLXNB2
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| Plexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivo.
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| Deng S, Hirschberg A, Worzfeld T, Penachioni JY, Korostylev A, Swiercz JM, Vodrazka P, Mauti O, Stoeckli ET, Tamagnone L, Offermanns S, Kuner R.
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| J Neurosci 27(23):6333-47.
2007
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17 | SEMA4D, PLXNB1
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| Sema4D/plexin-B1 activates GSK-3beta through R-Ras GAP activity, inducing growth cone collapse.
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| Ito Y, Oinuma I, Katoh H, Kaibuchi K, Negishi M.
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| EMBO Rep 7(7):704-9. Epub 2006 Jun 16. 2006
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18 | SEMA4D, PLXNB1
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| Sema4D induces angiogenesis through Met recruitment by Plexin B1.
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| Conrotto P, Valdembri D, Corso S, Serini G, Tamagnone L, Comoglio PM, Bussolino F, Giordano S.
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| Blood 105(11):4321-9. Epub 2005 Jan 4. 2005
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19 | PLXNB1, PLXNB2, PLXNB3, SEMA4D
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| Plexin-B family members demonstrate non-redundant expression patterns in the developing mouse nervous system: an anatomical basis for morphogenetic effects of Sema4D during development.
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| Worzfeld T, Püschel AW, Offermanns S, Kuner R.
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| Eur J Neurosci 19(10):2622-32.
2004
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20 | PLXNB1, ARHGEF11, ARHGEF12
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| Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factors.
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| Hirotani M, Ohoka Y, Yamamoto T, Nirasawa H, Furuyama T, Kogo M, Matsuya T, Inagaki S.
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| Biochem Biophys Res Commun 297(1):32-7. 2002
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21 | PLXNB1, RAC1, SEMA4D
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| The semaphorin receptor plexin-B1 specifically interacts with active rac in a ligand-dependent manner.
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| Vikis HG, Li W, He Z, Guan KL.
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| Proc Natl Acad Sci U S A 97(23):12457-62. 2000
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22 | PLXNA1, PLXNA2, PLXNA3, PLXNA4, PLXNB1, PLXNB2, PLXNB3, PLXNC1, PLXND1
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| Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.
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| Tamagnone L, Artigiani S, Chen H, He Z, Ming GI, Song H, Chedotal A, Winberg ML, Goodman CS, Poo M, Tessier-Lavigne M, Comoglio PM.
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| Cell 99(1):71-80. Erratum in: Cell 2001 Jan 26;104(2):following 320. 1999
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23 | PLXNA3, PLXNA1, PLXNA2, PLXNB1
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| A family of transmembrane proteins with homology to the MET-Hepatocyte growth factor receptor.
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| Maestrini E, et al.
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| Proc Natl Acad Sci U S A 93 : 674-678. 1996
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24 | PLXNA1, PLXNA2, PLXNA3, PLXNB1
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| Plexin : a novel neuronal cell surface molecule that mediates cell adhesion via a homophilic binding mechanism in the presence of calcium ions.
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| Ohta K, Mizutani A, Kawakami A, Murakami Y, Kasuya Y, Takagi S, Tanaka H, Fujisawa H.
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| Neuron 14 : 1189-1199. 1995
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