Citations for
1CARD11, PLEKHO1
CKIP-1 is an intrinsic negative regulator of T-cell activation through an interaction with CARMA1.
Sakamoto T, Kobayashi M, Tada K, Shinohara M, Io K, Nagata K, Iwai F, Takiuchi Y, Arai Y, Yamashita K, Shindo K, Kadowaki N, Koyanagi Y, Takaori-Kondo A.
PLoS One 9(1):e85762. doi: 10.1371/journal.pone.0085762. eCollection 2014. 2014
2PLEKHO1, SMURF1
CKIP-1 acts as a colonic tumor suppressor by repressing oncogenic Smurf1 synthesis and promoting Smurf1 autodegradation.
Nie J, Liu L, Xing G, Zhang M, Wei R, Guo M, Li X, Xie P, Li L, He F, Han W, Zhang L.
Oncogene 33(28):3677-87. doi: 10.1038/onc.2013.340. Epub 2013 Sep 2. 2014
3PLEKHO1, TRAF6
CKIP-1 regulates macrophage proliferation by inhibiting TRAF6-mediated Akt activation.
Zhang L, Wang Y, Xiao F, Wang S, Xing G, Li Y, Yin X, Lu K, Wei R, Fan J, Chen Y, Li T, Xie P, Yuan L, Song L, Ma L, Ding L, He F, Zhang L.
Cell Res 24(6):742-61. doi: 10.1038/cr.2014.53. Epub 2014 Apr 29. 2014
4PLEKHO1
CKIP-1: a scaffold protein and potential therapeutic target integrating multiple signaling pathways and physiological functions.
Nie J, Liu L, He F, Fu X, Han W, Zhang L.
Ageing Res Rev 12(1):276-81. doi: 10.1016/j.arr.2012.07.002. Epub 2012 Jul 31. Review. 2013
5PLEKHO1
Integrated analysis of genomics and proteomics reveals that CKIP-1 is a novel macrophage migration regulator.
Zhang L, Xia X, Zhang M, Wang Y, Xing G, Yin X, Song L, He F, Zhang L.
Biochem Biophys Res Commun 436(3):382-7. doi: 10.1016/j.bbrc.2013.05.109. Epub 2013 Jun 4. 2013
6PLEKHO1, PSMC5, SMURF1
CKIP-1 couples Smurf1 ubiquitin ligase with Rpt6 subunit of proteasome to promote substrate degradation.
Wang Y, Nie J, Wang Y, Zhang L, Lu K, Xing G, Xie P, He F, Zhang L.
EMBO Rep 13(11):1004-11. doi: 10.1038/embor.2012.144. Epub 2012 Oct 2. 2012
7PLEKHO1
CKIP-1 regulates mammalian and zebrafish myoblast fusion.
Baas D, Caussanel-Boude S, Guiraud A, Calhabeu F, Delaune E, Pilot F, Chopin E, Machuca-Gayet I, Vernay A, Bertrand S, Rual JF, Jurdic P, Hill DE, Vidal M, Schaeffer L, Goillot E.
J Cell Sci 125(Pt 16):3790-800. doi: 10.1242/jcs.101048. Epub 2012 May 2. 2012
8PLEKHO1
N-terminal PH domain and C-terminal auto-inhibitory region of CKIP-1 coordinate to determine its nucleus-plasma membrane shuttling.
Xi S, Tie Y, Lu K, Zhang M, Yin X, Chen J, Xing G, Tian C, Zheng X, He F, Zhang L.
FEBS Lett 584(6):1223-30. Epub 2010 Feb 18.PMID: 20171213 2010
9PLEKHO1
Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1.
Lu K, Yin X, Weng T, Xi S, Li L, Xing G, Cheng X, Yang X, Zhang L, He F.
Nat Cell Biol 10(8):994-1002. Epub 2008 Jul 20.PMID: 18641638 2008
10PLEKHO1
Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo.
Tokuda E, Fujita N, Oh-hara T, Sato S, Kurata A, Katayama R, Itoh T, Takenawa T, Miyazono K, Tsuruo T.
Cancer Res 67(20):9666-76.PMID: 17942896 2007
11PLEKHO1
The PH domain containing protein CKIP-1 binds to IFP35 and Nmi and is involved in cytokine signaling.
Zhang L, Tang Y, Tie Y, Tian C, Wang J, Dong Y, Sun Z, He F.
Cell Signal 19(5):932-44. Epub 2006 Nov 17.PMID: 17197158 2007
12IFI35, NMI, PLEKHO1
The PH domain containing protein CKIP-1 binds to IFP35 and Nmi and is involved in cytokine signaling.
Zhang L, Tang Y, Tie Y, Tian C, Wang J, Dong Y, Sun Z, He F.
Cell Signal 19(5):932-44. Epub 2006 Nov 17. 2007
13PLEKHO1
CKIP-1 recruits nuclear ATM partially to the plasma membrane through interaction with ATM.
Zhang L, Tie Y, Tian C, Xing G, Song Y, Zhu Y, Sun Z, He F.
Cell Signal 18(9):1386-95. Epub 2005 Dec 1. 2006
14PLEKHO1
The role of CKIP-1 in cell morphology depends on its interaction with actin-capping protein.
Canton DA, Olsten ME, Niederstrasser H, Cooper JA, Litchfield DW.
J Biol Chem 281(47):36347-59. Epub 2006 Sep 20.PMID: 16987810 2006
15PLEKHO1
The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein.
Canton DA, Olsten ME, Kim K, Doherty-Kirby A, Lajoie G, Cooper JA, Litchfield DW.
Mol Cell Biol 25(9):3519-34. 2005
16PLEKHO1
Role for the pleckstrin homology domain-containing protein CKIP-1 in AP-1 regulation and apoptosis.
Zhang L, Xing G, Tie Y, Tang Y, Tian C, Li L, Sun L, Wei H, Zhu Y, He F.
EMBO J 24(4):766-78. Epub 2005 Feb 10. 2005
17PLEKHO1
The Pleckstrin homology domain of CK2 interacting protein-1 is required for interactions and recruitment of protein kinase CK2 to the plasma membrane.
Olsten ME, Canton DA, Zhang C, Walton PA, Litchfield DW.
J Biol Chem 279(40):42114-27. Epub 2004 Jul 14. 2004
18PLEKHO1
Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2.
Bosc DG, Graham KC, Saulnier RB, Zhang C, Prober D, Gietz RD, Litchfield DW.
J Biol Chem 275(19):14295-306. 2000