1 | CARD11, PLEKHO1
|
| CKIP-1 is an intrinsic negative regulator of T-cell activation through an interaction with CARMA1.
|
| Sakamoto T, Kobayashi M, Tada K, Shinohara M, Io K, Nagata K, Iwai F, Takiuchi Y, Arai Y, Yamashita K, Shindo K, Kadowaki N, Koyanagi Y, Takaori-Kondo A.
|
| PLoS One 9(1):e85762. doi: 10.1371/journal.pone.0085762. eCollection 2014.
2014
|
2 | PLEKHO1, SMURF1
|
| CKIP-1 acts as a colonic tumor suppressor by repressing oncogenic Smurf1 synthesis and promoting Smurf1 autodegradation.
|
| Nie J, Liu L, Xing G, Zhang M, Wei R, Guo M, Li X, Xie P, Li L, He F, Han W, Zhang L.
|
| Oncogene 33(28):3677-87. doi: 10.1038/onc.2013.340. Epub 2013 Sep 2.
2014
|
3 | PLEKHO1, TRAF6
|
| CKIP-1 regulates macrophage proliferation by inhibiting TRAF6-mediated Akt activation.
|
| Zhang L, Wang Y, Xiao F, Wang S, Xing G, Li Y, Yin X, Lu K, Wei R, Fan J, Chen Y, Li T, Xie P, Yuan L, Song L, Ma L, Ding L, He F, Zhang L.
|
| Cell Res 24(6):742-61. doi: 10.1038/cr.2014.53. Epub 2014 Apr 29.
2014
|
4 | PLEKHO1
|
| CKIP-1: a scaffold protein and potential therapeutic target integrating multiple signaling pathways and physiological functions.
|
| Nie J, Liu L, He F, Fu X, Han W, Zhang L.
|
| Ageing Res Rev 12(1):276-81. doi: 10.1016/j.arr.2012.07.002. Epub 2012 Jul 31. Review.
2013
|
5 | PLEKHO1
|
| Integrated analysis of genomics and proteomics reveals that CKIP-1 is a novel macrophage migration regulator.
|
| Zhang L, Xia X, Zhang M, Wang Y, Xing G, Yin X, Song L, He F, Zhang L.
|
| Biochem Biophys Res Commun 436(3):382-7. doi: 10.1016/j.bbrc.2013.05.109. Epub 2013 Jun 4.
2013
|
6 | PLEKHO1, PSMC5, SMURF1
|
| CKIP-1 couples Smurf1 ubiquitin ligase with Rpt6 subunit of proteasome to promote substrate degradation.
|
| Wang Y, Nie J, Wang Y, Zhang L, Lu K, Xing G, Xie P, He F, Zhang L.
|
| EMBO Rep 13(11):1004-11. doi: 10.1038/embor.2012.144. Epub 2012 Oct 2.
2012
|
7 | PLEKHO1
|
| CKIP-1 regulates mammalian and zebrafish myoblast fusion.
|
| Baas D, Caussanel-Boude S, Guiraud A, Calhabeu F, Delaune E, Pilot F, Chopin E, Machuca-Gayet I, Vernay A, Bertrand S, Rual JF, Jurdic P, Hill DE, Vidal M, Schaeffer L, Goillot E.
|
| J Cell Sci 125(Pt 16):3790-800. doi: 10.1242/jcs.101048. Epub 2012 May 2.
2012
|
8 | PLEKHO1
|
| N-terminal PH domain and C-terminal auto-inhibitory region of CKIP-1 coordinate to determine its nucleus-plasma membrane shuttling.
|
| Xi S, Tie Y, Lu K, Zhang M, Yin X, Chen J, Xing G, Tian C, Zheng X, He F, Zhang L.
|
| FEBS Lett 584(6):1223-30. Epub 2010 Feb 18.PMID: 20171213 2010
|
9 | PLEKHO1
|
| Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1.
|
| Lu K, Yin X, Weng T, Xi S, Li L, Xing G, Cheng X, Yang X, Zhang L, He F.
|
| Nat Cell Biol 10(8):994-1002. Epub 2008 Jul 20.PMID: 18641638 2008
|
10 | PLEKHO1
|
| Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo.
|
| Tokuda E, Fujita N, Oh-hara T, Sato S, Kurata A, Katayama R, Itoh T, Takenawa T, Miyazono K, Tsuruo T.
|
| Cancer Res 67(20):9666-76.PMID: 17942896 2007
|
11 | PLEKHO1
|
| The PH domain containing protein CKIP-1 binds to IFP35 and Nmi and is involved in cytokine signaling.
|
| Zhang L, Tang Y, Tie Y, Tian C, Wang J, Dong Y, Sun Z, He F.
|
| Cell Signal 19(5):932-44. Epub 2006 Nov 17.PMID: 17197158 2007
|
12 | IFI35, NMI, PLEKHO1
|
| The PH domain containing protein CKIP-1 binds to IFP35 and Nmi and is involved in cytokine signaling.
|
| Zhang L, Tang Y, Tie Y, Tian C, Wang J, Dong Y, Sun Z, He F.
|
| Cell Signal 19(5):932-44. Epub 2006 Nov 17.
2007
|
13 | PLEKHO1
|
| CKIP-1 recruits nuclear ATM partially to the plasma membrane through interaction with ATM.
|
| Zhang L, Tie Y, Tian C, Xing G, Song Y, Zhu Y, Sun Z, He F.
|
| Cell Signal 18(9):1386-95. Epub 2005 Dec 1. 2006
|
14 | PLEKHO1
|
| The role of CKIP-1 in cell morphology depends on its interaction with actin-capping protein.
|
| Canton DA, Olsten ME, Niederstrasser H, Cooper JA, Litchfield DW.
|
| J Biol Chem 281(47):36347-59. Epub 2006 Sep 20.PMID: 16987810 2006
|
15 | PLEKHO1
|
| The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein.
|
| Canton DA, Olsten ME, Kim K, Doherty-Kirby A, Lajoie G, Cooper JA, Litchfield DW.
|
| Mol Cell Biol 25(9):3519-34. 2005
|
16 | PLEKHO1
|
| Role for the pleckstrin homology domain-containing protein CKIP-1 in AP-1 regulation and apoptosis.
|
| Zhang L, Xing G, Tie Y, Tang Y, Tian C, Li L, Sun L, Wei H, Zhu Y, He F.
|
| EMBO J 24(4):766-78. Epub 2005 Feb 10. 2005
|
17 | PLEKHO1
|
| The Pleckstrin homology domain of CK2 interacting protein-1 is required for interactions and recruitment of protein kinase CK2 to the plasma membrane.
|
| Olsten ME, Canton DA, Zhang C, Walton PA, Litchfield DW.
|
| J Biol Chem 279(40):42114-27. Epub 2004 Jul 14. 2004
|
18 | PLEKHO1
|
| Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2.
|
| Bosc DG, Graham KC, Saulnier RB, Zhang C, Prober D, Gietz RD, Litchfield DW.
|
| J Biol Chem 275(19):14295-306. 2000
|