| 1 | AKT2, PLEKHG4, RAC1
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| Role of the guanine nucleotide exchange factor in Akt2-mediated plasma membrane translocation of GLUT4 in insulin-stimulated skeletal muscle.
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| Takenaka N, Yasuda N, Nihata Y, Hosooka T, Noguchi T, Aiba A, Satoh T.
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| Cell Signal 26(11):2460-9. doi: 10.1016/j.cellsig.2014.07.002. Epub 2014 Jul 12.
2014
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| 2 | PLEKHG4
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| Plekhg4 is a novel Dbl family guanine nucleotide exchange factor protein for rho family GTPases.
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| Gupta M, Kamynina E, Morley S, Chung S, Muakkassa N, Wang H, Brathwaite S, Sharma G, Manor D.
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| J Biol Chem 288(20):14522-30. doi: 10.1074/jbc.M112.430371. Epub 2013 Apr 9.
2013
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| 3 | PLEKHG4, SCA4
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| Clinical and genetic characterization of 16q-linked autosomal dominant spinocerebellar ataxia in South Kyushu, Japan.
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| Hirano R, Takashima H, Okubo R, Okamoto Y, Maki Y, Ishida S, Suehara M, Hokezu Y, Arimura K.
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| J Hum Genet 54(7):377-81. Epub 2009 May 15.
2009
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| 4 | PLEKHG4
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| Activation of the small GTPase Rac1 by a specific guanine-nucleotide-exchange factor suffices to induce glucose uptake into skeletal-muscle cells.
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| Ueda S, Kataoka T, Satoh T.
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| Biol Cell 100(11):645-57. doi: 10.1042/BC20070160.
2008
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| 5 | PLEKHG4,SCA4
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| Redefining the disease locus of 16q22.1-linked autosomal dominant cerebellar ataxia.
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| Amino T, Ishikawa K, Toru S, Ishiguro T, Sato N, Tsunemi T, Murata M, Kobayashi K, Inazawa J, Toda T, Mizusawa H.
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| J Hum Genet 52(8):643-9. Epub 2007 Jul 5. 2007
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| 6 | PLEKHG4, SCA4
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| Clinical and genetic characterizations of 16q-linked autosomal dominant spinocerebellar ataxia (AD-SCA) and frequency analysis of AD-SCA in the Japanese population.
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| Nozaki H, Ikeuchi T, Kawakami A, Kimura A, Koide R, Tsuchiya M, Nakmura Y, Mutoh T, Yamamoto H, Nakao N, Sahashi K, Nishizawa M, Onodera O.
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| Mov Disord 22(6):857-62.
2007
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| 7 | PLEKHG4, SCA4
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| Mutations of the puratrophin-1 (PLEKHG4) gene on chromosome 16q22.1 are not a common genetic cause of cerebellar ataxia in a European population.
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| Wieczorek S, Arning L, Alheite I, Epplen JT.
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| J Hum Genet 51(4):363-7. Epub 2006 Feb 21. 2006
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| 8 | PLEKHG4, SCA4
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| 16q-linked autosomal dominant cerebellar ataxia: a clinical and genetic study.
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| Ouyang Y, Sakoe K, Shimazaki H, Namekawa M, Ogawa T, Ando Y, Kawakami T, Kaneko J, Hasegawa Y, Yoshizawa K, Amino T, Ishikawa K, Mizusawa H, Nakano I, Takiyama Y.
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| J Neurol Sci 247(2):180-6. Epub 2006 Jun 15. 2006
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| 9 | PLEKHG4, SCA31, SCA4
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| An autosomal dominant cerebellar ataxia linked to chromosome 16q22.1 is associated with a single-nucleotide substitution in the 5' untranslated region of the gene encoding a protein with spectrin repeat and rho Guanine-nucleotide exchange-factor domains.
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| Ishikawa K, Toru S, Tsunemi T, Li M, Kobayashi K, Yokota T, Amino T, Owada K, Fujigasaki H, Sakamoto M, Tomimitsu H, Takashima M, Kumagai J, Noguchi Y, Kawashima Y, Ohkoshi N, Ishida G, Gomyoda M, Yoshida M, Hashizume Y, Saito Y, Murayama S, Yamanouchi H, Mizutani T, Kondo I, Toda T, Mizusawa H.
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| Am J Hum Genet 77(2):280-96. Epub 2005 Jul 6. 2005
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