| 1 | PLD3
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| PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer's disease
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| Nackenoff AG, Hohman TJ, Neuner SM, Akers CS, Weitzel NC, Shostak A, Ferguson SM, Mobley B, Bennett DA, Schneider JA, Jefferson AL, Kaczorowski CC, Schrag MS.
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| PLoS Genet. Apr 8;17(4):e1009406. doi: 10.1371/journal.pgen.1009406. 2021
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| 2 | PLD3, PLD4
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| Modulators of immunoregulatory exonucleases PLD3 and PLD4 identified by high-throughput screen
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| Shirey RJ, Turner LD, Lairson LL, Janda KD.
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| Bioorg Med Chem Lett. Oct 1;49:128293. doi: 10.1016/j.bmcl.2021.128293. Epub 2021 Jul 28. 2021
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| 3 | PLD3, PLD4
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| Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors
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| Gavin AL, Huang D, Blane TR, Thinnes TC, Murakami Y, Fukui R, Miyake K, Nemazee D.
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| Nat Commun. Oct 7;12(1):5874. doi: 10.1038/s41467-021-26150-w. 2021
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| 4 | PLD3, PLD4
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| Quantification and characterization of the 5' exonuclease activity of the lysosomal nuclease PLD3 by a novel cell-based assay.
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| Cappel C, Gonzalez AC, Damme M.
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| J Biol Chem. Jan-Jun;296:100152. doi: 10.1074/jbc.RA120.015867. Epub 2020 Dec 10 2021
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| 5 | PLD3
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| PLD3 epigenetic changes in the hippocampus of Alzheimer's disease
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| Blanco-Luquin I, Altuna M, Sánchez-Ruiz de Gordoa J, Urdánoz-Casado A, Roldán M, Cámara M, Zelaya V, Erro ME, Echavarri C, Mendioroz M.
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| Clin Epigenetics Sep 12;10(1):116. doi: 10.1186/s13148-018-0547-3. 2018
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| 6 | PLD3, PLD4
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| PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing.
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| Gavin AL, Huang D, Huber C, Mårtensson A, Tardif V, Skog PD, Blane TR, Thinnes TC, Osborn K, Chong HS, Kargaran F, Kimm P, Zeitjian A, Sielski RL, Briggs M, Schulz SR, Zarpellon A, Cravatt B, Pang ES, Teijaro J, de la Torre JC, O'Keeffe M, Hochrein H, Damme M, Teyton L, Lawson BR, Nemazee D.
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| Nat Immunol. Sep;19(9):942-953. doi: 10.1038/s41590-018-0179-y. Epub 2018 Aug 13. 2018
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| 7 | PLD3
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| Unconventional Trafficking of Mammalian Phospholipase D3 to Lysosomes
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| Gonzalez AC, Schweizer M, Jagdmann S, Bernreuther C, Reinheckel T, Saftig P, Damme M.
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| Cell Rep. Jan 23;22(4):1040-1053. doi: 10.1016/j.celrep.2017.12.100. Epub 2018 Jan 28. 2018
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| 8 | FAT2, PLD3, SCA45, SCA46
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| Exome sequencing and network analysis identifies shared mechanisms underlying spinocerebellar ataxia
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| Nibbeling EAR, Duarri A, Verschuuren-Bemelmans CC, Fokkens MR, Karjalainen JM, Smeets CJLM, de Boer-Bergsma JJ, van der Vries G, Dooijes D, Bampi GB, van Diemen C, Brunt E, Ippel E, Kremer B, Vlak M, Adir N, Wijmenga C, van de Warrenburg BPC, Franke L, Sinke RJ, Verbeek DS
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| Brain Nov 1;140(11):2860-2878. doi: 10.1093/brain/awx251 2017
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| 9 | PLD3
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| PLD3 in Alzheimer's disease
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| Wang J, Yu JT, Tan L.
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| Mol Neurobiol. Apr;51(2):480-6. doi: 10.1007/s12035-014-8779-5. Epub 2014 Jun 17. 2015
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| 10 | PLD3
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| PLD3 and sporadic Alzheimer's disease risk.
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| Lambert JC, Grenier-Boley B, Bellenguez C, Pasquier F, Campion D, Dartigues JF, Berr C, Tzourio C, Amouyel P.
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| Nature. Apr 2;520(7545):E1. doi: 10.1038/nature14036. 2015
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| 11 | PLD3
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| A role for phospholipase D3 in myotube formation.
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| Osisami M, Ali W, Frohman MA.
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| PLoS One ;7(3):e33341. doi: 10.1371/journal.pone.0033341. Epub 2012 Mar 12. 2012
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| 12 | PLD3
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| Hu-K4 is a ubiquitously expressed type 2 transmembrane protein associated with the endoplasmic reticulum.
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| Munck A, Bohm C, Seibel NM, Hashemol Hosseini Z, Hampe W.
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| FEBS J 272(7):1718-26. 2005
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| 13 | PLD3
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| Expression of a novel murine phospholipase D homolog coincides with late neuronal development in the forebrain.
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| Pedersen KM, Finsen B, Celis JE, Jensen NA.
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| J Biol Chem 273(47):31494-504. 1998
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| 14 | PLD3
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| A human homolog of the vaccinia virus HindIII K4L gene is a member of the phospholipase D superfamily.
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| Cao JX, Koop BF, Upton C.
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| Virus Res 48(1):11-8. 1997
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