1 | ADRA1B, CACNA1C, PLD1
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| Phospholipase D1 is involved in α1-adrenergic contraction of murine vascular smooth muscle.
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| Wegener JW, Loga F, Stegner D, Nieswandt B, Hofmann F.
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| FASEB J 28(3):1044-8. doi: 10.1096/fj.13-237925. Epub 2013 Nov 19.
2014
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2 | PLD1, PLD2
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| Deficiencies of the lipid-signaling enzymes phospholipase D1 and D2 alter cytoskeletal organization, macrophage phagocytosis, and cytokine-stimulated neutrophil recruitment.
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| Ali WH, Chen Q, Delgiorno KE, Su W, Hall JC, Hongu T, Tian H, Kanaho Y, Di Paolo G, Crawford HC, Frohman MA.
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| PLoS One 8(1):e55325. doi: 10.1371/journal.pone.0055325. Epub 2013 Jan 28.
2013
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3 | PLD1
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| Phospholipase D1 is involved in α1-adrenergic contraction of murine vascular smooth muscle.
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| Wegener JW, Loga F, Stegner D, Nieswandt B, Hofmann F.
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| FASEB J ASEB J. 2013 Nov 19. [Epub ahead of print]
2013
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4 | FAM83B, PLD1
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| Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B.
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| Cipriano R, Bryson BL, Miskimen KL, Bartel CA, Hernandez-Sanchez W, Bruntz RC, Scott SA, Lindsley CW, Brown HA, Jackson MW.
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| Oncogene ncogene. 2013 Aug 5. doi: 10.1038/onc.2013.293. [Epub ahead of print]
2013
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5 | HRAS, PEA15, PLD1
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| PEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase D.
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| Sulzmaier FJ, Valmiki MK, Nelson DA, Caliva MJ, Geerts D, Matter ML, White EP, Ramos JW.
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| Oncogene 31(30):3547-60. doi: 10.1038/onc.2011.514. Epub 2011 Nov 21.
2012
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6 | FES, PLD1, PLD2
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| Phospholipase D2 (PLD2) shortens the time required for myeloid leukemic cell differentiation: mechanism of action.
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| Di Fulvio M, Frondorf K, Henkels KM, Grunwald WC Jr, Cool D, Gomez-Cambronero J.
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| J Biol Chem 287(1):393-407. doi: 10.1074/jbc.M111.259465. Epub 2011 Nov 17.
2012
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7 | PLD1
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| Key roles for the lipid signaling enzyme phospholipase d1 in the tumor microenvironment during tumor angiogenesis and metastasis.
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| Chen Q, Hongu T, Sato T, Zhang Y, Ali W, Cavallo JA, van der Velden A, Tian H, Di Paolo G, Nieswandt B, Kanaho Y, Frohman MA.
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| Sci Signal 5(249):ra79. doi: 10.1126/scisignal.2003257.
2012
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8 | PLD1
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| The hydrophobic amino acids involved in the interdomain association of phospholipase D1 regulate the shuttling of phospholipase D1 from vesicular organelles into the nucleus.
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| Jang YH, Min do S.
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| Exp Mol Med 44(10):571-7. doi: 10.3858/emm.2012.44.10.065.
2012
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9 | PLD1, RHOA
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| PLD1 Negatively Regulates Dendritic Branching.
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| Zhu YB, Kang K, Zhang Y, Qi C, Li G, Yin DM, Wang Y.
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| J Neurosci 32(23):7960-9. doi: 10.1523/JNEUROSCI.5378-11.2012.
2012
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10 | PLD1
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| Nuclear localization of phospholipase D1 mediates the activation of nuclear protein kinase C(alpha) and extracellular signal-regulated kinase signaling pathways.
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| Jang YH, Min do S.
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| J Biol Chem 286(6):4680-9. doi: 10.1074/jbc.M110.162602. Epub 2010 Nov 27.
2011
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11 | PIK3C3, PLD1
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| Class III PI-3-kinase activates phospholipase D in an amino acid-sensing mTORC1 pathway.
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| Yoon MS, Du G, Backer JM, Frohman MA, Chen J.
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| J Cell Biol 195(3):435-47. doi: 10.1083/jcb.201107033. Epub 2011 Oct 24.
2011
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12 | PLD1
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| Role of phospholipase D1 in glucose-induced insulin secretion in pancreatic Beta cells.
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| Ma WN, Park SY, Han JS.
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| Exp Mol Med 42(6):456-64.
2010
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13 | PLD1
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| Phospholipase D1 mediates AMP-activated protein kinase signaling for glucose uptake.
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| Kim JH, Park JM, Yea K, Kim HW, Suh PG, Ryu SH.
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| PLoS One 5(3):e9600. doi: 10.1371/journal.pone.0009600.
2010
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14 | PLD1
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| Developmental levels of phospholipase D isozymes in the brain of developing rats.
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| Kim M, Moon C, Kim H, Shin MK, Min do S, Shin T.
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| Acta Histochem 112(1):81-91. doi: 10.1016/j.acthis.2008.09.004. Epub 2008 Nov 17.
2010
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15 | PLD1, PLD2, PLD5
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| Phospholipase d promotes lipid microdomain-associated signaling events in mast cells.
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| Lisboa FA, Peng Z, Combs CA, Beaven MA.
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| J Immunol 183(8):5104-12. doi: 10.4049/jimmunol.0802728. Epub 2009 Sep 30. 2009
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16 | PLD1, PSEN1
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| Intracellular trafficking of presenilin 1 is regulated by beta-amyloid precursor protein and phospholipase D1.
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| Liu Y, Zhang YW, Wang X, Zhang H, You X, Liao FF, Xu H.
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| J Biol Chem 284(18):12145-52. doi: 10.1074/jbc.M808497200. Epub 2009 Mar 10.
2009
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17 | PLD1, VWF
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| Phospholipase D1 is specifically required for regulated secretion of von Willebrand factor from endothelial cells.
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| Disse J, Vitale N, Bader MF, Gerke V.
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| Blood 113(4):973-80. doi: 10.1182/blood-2008-06-165282. Epub 2008 Oct 22.
2009
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18 | RPS6KA3, PLD1, SCRIB
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| The Coffin-Lowry syndrome-associated protein RSK2 is implicated in calcium-regulated exocytosis through the regulation of PLD1.
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| Zeniou-Meyer M, Liu Y, BŽglŽ A, Olanish M, Hanauer A, Becherer U, Rettig J, Bader MF, Vitale N.
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| Proc Natl Acad Sci U S A 105(24):8434-9. Epub 2008 Jun 11. 2008
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19 | PLD1
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| Interaction of PLD1b with actin in antigen-stimulated mast cells.
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| Farquhar MJ, Powner DJ, Levine BA, Wright MH, Ladds G, Hodgkin MN.
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| Cell Signal 19(2):349-58. Epub 2006 Jul 28. 2007
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20 | PLD1
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| Phospholipase D protects ECV304 cells against TNFalpha-induced apoptosis.
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| Birbes H, Zeiller C, Komati H, NŽmoz G, Lagarde M, Prigent AF.
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| FEBS Lett 580(26):6224-32. Epub 2006 Oct 19. 2006
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21 | TEK, ANGPT1, PLD1
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| Localization of Tie2 and phospholipase D in endothelial caveolae is involved in angiopoietin-1-induced MEK/ERK phosphorylation and migration in endothelial cells.
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| Yoon MJ, Cho CH, Lee CS, Jang IH, Ryu SH, Koh GY.
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| Biochem Biophys Res Commun 308(1):101-5. 2003
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22 | PLD1, PLD2
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| Regulation of human PLD1 and PLD2 by calcium and protein kinase C.
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| Siddiqi AR, Srajer GE, Leslie CC.
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| Biochim Biophys Acta 1497(1):103-14. 2000
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23 | PLD1
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| Structural analysis of human phospholipase D1.
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| Sung TC, et al.
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| J Biol Chem 274(6):3659-66. 1999
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24 | PLD1
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| Assignment of human PLD1 to human chromosome band 3q26 by fluorescence in situ hybridization.
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| Park SH, et al.
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| Cytogenet Cell Genet 82 : 224. 1998
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25 | PLD1, PLD2
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| Characterization of human PLD2 and the analysis of PLD isoform splice variants.
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| Steed PM, Clark KL, Boyar WC, Lasala DJ.
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| FASEB J 12 : 1309-1317. 1998
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26 | PLD1
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| Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alpha.
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| Hammond SM, et al.
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| J Biol Chem 272 : 3860-3868. 1997
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27 | PLD1, PLD2
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| Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization.
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| Colley WC, Sung TC, Roll R, Jenco J, Hammond SM, Altshuller Y, Bar-Sagi D, Morris AJ, Frohman MA.
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| Curr Biol 7(3):191-201. 1997
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28 | PLD1
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| Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family.
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| Hammond SM, et al.
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| J Biol Chem 270 : 29640-20643. 1995
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