Citations for
1ADRA1B, CACNA1C, PLD1
Phospholipase D1 is involved in α1-adrenergic contraction of murine vascular smooth muscle.
Wegener JW, Loga F, Stegner D, Nieswandt B, Hofmann F.
FASEB J 28(3):1044-8. doi: 10.1096/fj.13-237925. Epub 2013 Nov 19. 2014
2PLD1, PLD2
Deficiencies of the lipid-signaling enzymes phospholipase D1 and D2 alter cytoskeletal organization, macrophage phagocytosis, and cytokine-stimulated neutrophil recruitment.
Ali WH, Chen Q, Delgiorno KE, Su W, Hall JC, Hongu T, Tian H, Kanaho Y, Di Paolo G, Crawford HC, Frohman MA.
PLoS One 8(1):e55325. doi: 10.1371/journal.pone.0055325. Epub 2013 Jan 28. 2013
3PLD1
Phospholipase D1 is involved in α1-adrenergic contraction of murine vascular smooth muscle.
Wegener JW, Loga F, Stegner D, Nieswandt B, Hofmann F.
FASEB J ASEB J. 2013 Nov 19. [Epub ahead of print] 2013
4FAM83B, PLD1
Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B.
Cipriano R, Bryson BL, Miskimen KL, Bartel CA, Hernandez-Sanchez W, Bruntz RC, Scott SA, Lindsley CW, Brown HA, Jackson MW.
Oncogene ncogene. 2013 Aug 5. doi: 10.1038/onc.2013.293. [Epub ahead of print] 2013
5HRAS, PEA15, PLD1
PEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase D.
Sulzmaier FJ, Valmiki MK, Nelson DA, Caliva MJ, Geerts D, Matter ML, White EP, Ramos JW.
Oncogene 31(30):3547-60. doi: 10.1038/onc.2011.514. Epub 2011 Nov 21. 2012
6FES, PLD1, PLD2
Phospholipase D2 (PLD2) shortens the time required for myeloid leukemic cell differentiation: mechanism of action.
Di Fulvio M, Frondorf K, Henkels KM, Grunwald WC Jr, Cool D, Gomez-Cambronero J.
J Biol Chem 287(1):393-407. doi: 10.1074/jbc.M111.259465. Epub 2011 Nov 17. 2012
7PLD1
Key roles for the lipid signaling enzyme phospholipase d1 in the tumor microenvironment during tumor angiogenesis and metastasis.
Chen Q, Hongu T, Sato T, Zhang Y, Ali W, Cavallo JA, van der Velden A, Tian H, Di Paolo G, Nieswandt B, Kanaho Y, Frohman MA.
Sci Signal 5(249):ra79. doi: 10.1126/scisignal.2003257. 2012
8PLD1
The hydrophobic amino acids involved in the interdomain association of phospholipase D1 regulate the shuttling of phospholipase D1 from vesicular organelles into the nucleus.
Jang YH, Min do S.
Exp Mol Med 44(10):571-7. doi: 10.3858/emm.2012.44.10.065. 2012
9PLD1, RHOA
PLD1 Negatively Regulates Dendritic Branching.
Zhu YB, Kang K, Zhang Y, Qi C, Li G, Yin DM, Wang Y.
J Neurosci 32(23):7960-9. doi: 10.1523/JNEUROSCI.5378-11.2012. 2012
10PLD1
Nuclear localization of phospholipase D1 mediates the activation of nuclear protein kinase C(alpha) and extracellular signal-regulated kinase signaling pathways.
Jang YH, Min do S.
J Biol Chem 286(6):4680-9. doi: 10.1074/jbc.M110.162602. Epub 2010 Nov 27. 2011
11PIK3C3, PLD1
Class III PI-3-kinase activates phospholipase D in an amino acid-sensing mTORC1 pathway.
Yoon MS, Du G, Backer JM, Frohman MA, Chen J.
J Cell Biol 195(3):435-47. doi: 10.1083/jcb.201107033. Epub 2011 Oct 24. 2011
12PLD1
Role of phospholipase D1 in glucose-induced insulin secretion in pancreatic Beta cells.
Ma WN, Park SY, Han JS.
Exp Mol Med 42(6):456-64. 2010
13PLD1
Phospholipase D1 mediates AMP-activated protein kinase signaling for glucose uptake.
Kim JH, Park JM, Yea K, Kim HW, Suh PG, Ryu SH.
PLoS One 5(3):e9600. doi: 10.1371/journal.pone.0009600. 2010
14PLD1
Developmental levels of phospholipase D isozymes in the brain of developing rats.
Kim M, Moon C, Kim H, Shin MK, Min do S, Shin T.
Acta Histochem 112(1):81-91. doi: 10.1016/j.acthis.2008.09.004. Epub 2008 Nov 17. 2010
15PLD1, PLD2, PLD5
Phospholipase d promotes lipid microdomain-associated signaling events in mast cells.
Lisboa FA, Peng Z, Combs CA, Beaven MA.
J Immunol 183(8):5104-12. doi: 10.4049/jimmunol.0802728. Epub 2009 Sep 30. 2009
16PLD1, PSEN1
Intracellular trafficking of presenilin 1 is regulated by beta-amyloid precursor protein and phospholipase D1.
Liu Y, Zhang YW, Wang X, Zhang H, You X, Liao FF, Xu H.
J Biol Chem 284(18):12145-52. doi: 10.1074/jbc.M808497200. Epub 2009 Mar 10. 2009
17PLD1, VWF
Phospholipase D1 is specifically required for regulated secretion of von Willebrand factor from endothelial cells.
Disse J, Vitale N, Bader MF, Gerke V.
Blood 113(4):973-80. doi: 10.1182/blood-2008-06-165282. Epub 2008 Oct 22. 2009
18RPS6KA3, PLD1, SCRIB
The Coffin-Lowry syndrome-associated protein RSK2 is implicated in calcium-regulated exocytosis through the regulation of PLD1.
Zeniou-Meyer M, Liu Y, Béglé A, Olanish M, Hanauer A, Becherer U, Rettig J, Bader MF, Vitale N.
Proc Natl Acad Sci U S A 105(24):8434-9. Epub 2008 Jun 11. 2008
19PLD1
Interaction of PLD1b with actin in antigen-stimulated mast cells.
Farquhar MJ, Powner DJ, Levine BA, Wright MH, Ladds G, Hodgkin MN.
Cell Signal 19(2):349-58. Epub 2006 Jul 28. 2007
20PLD1
Phospholipase D protects ECV304 cells against TNFalpha-induced apoptosis.
Birbes H, Zeiller C, Komati H, Némoz G, Lagarde M, Prigent AF.
FEBS Lett 580(26):6224-32. Epub 2006 Oct 19. 2006
21TEK, ANGPT1, PLD1
Localization of Tie2 and phospholipase D in endothelial caveolae is involved in angiopoietin-1-induced MEK/ERK phosphorylation and migration in endothelial cells.
Yoon MJ, Cho CH, Lee CS, Jang IH, Ryu SH, Koh GY.
Biochem Biophys Res Commun 308(1):101-5. 2003
22PLD1, PLD2
Regulation of human PLD1 and PLD2 by calcium and protein kinase C.
Siddiqi AR, Srajer GE, Leslie CC.
Biochim Biophys Acta 1497(1):103-14. 2000
23PLD1
Structural analysis of human phospholipase D1.
Sung TC, et al.
J Biol Chem 274(6):3659-66. 1999
24PLD1
Assignment of human PLD1 to human chromosome band 3q26 by fluorescence in situ hybridization.
Park SH, et al.
Cytogenet Cell Genet 82 : 224. 1998
25PLD1, PLD2
Characterization of human PLD2 and the analysis of PLD isoform splice variants.
Steed PM, Clark KL, Boyar WC, Lasala DJ.
FASEB J 12 : 1309-1317. 1998
26PLD1
Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alpha.
Hammond SM, et al.
J Biol Chem 272 : 3860-3868. 1997
27PLD1, PLD2
Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization.
Colley WC, Sung TC, Roll R, Jenco J, Hammond SM, Altshuller Y, Bar-Sagi D, Morris AJ, Frohman MA.
Curr Biol 7(3):191-201. 1997
28PLD1
Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family.
Hammond SM, et al.
J Biol Chem 270 : 29640-20643. 1995