1 | PLCB2, WDR26
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| WDR26 Functions as a Scaffolding Protein to Promote Gβγ-mediated Phospholipase C β2 (PLCβ2) Activation in Leukocytes.
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| Sun Z, Smrcka AV, Chen S.
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| J Biol Chem 288(23):16715-25. doi: 10.1074/jbc.M113.462564. Epub 2013 Apr 26.
2013
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2 | GNAQ, PLCB2, SNCG
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| γ-Synuclein interacts with phospholipase Cβ2 to modulate G protein activation.
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| Golebiewska U, Guo Y, Khalikaprasad N, Zurawsky C, Yerramilli VS, Scarlata S.
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| PLoS One 7(8):e41067. doi: 10.1371/journal.pone.0041067. Epub 2012 Aug 8.
2012
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3 | CXCR2, PLCB2, SLC9A3R1
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| A chemokine receptor CXCR2 macromolecular complex regulates neutrophil functions in inflammatory diseases.
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| Wu Y, Wang S, Farooq SM, Castelvetere MP, Hou Y, Gao JL, Navarro JV, Oupicky D, Sun F, Li C.
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| J Biol Chem 287(8):5744-55. doi: 10.1074/jbc.M111.315762. Epub 2011 Dec 27.
2012
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4 | GNAQ, PLCB2, WDR36
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| WDR36 acts as a scaffold protein tethering a G-protein-coupled receptor, Gαq and phospholipase Cβ in a signalling complex.
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| Cartier A, Parent A, Labrecque P, Laroche G, Parent JL.
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| J Cell Sci 124(Pt 19):3292-304. doi: 10.1242/jcs.085795.
2011
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5 | PLCB2, PLCD1
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| The small G protein Rac1 activates phospholipase Cdelta1 through phospholipase Cbeta2.
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| Guo Y, Golebiewska U, D'Amico S, Scarlata S.
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| J Biol Chem 285(32):24999-5008. doi: 10.1074/jbc.M110.132654. Epub 2010 Jun 8.
2010
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6 | PLCB2
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| Suppression of PLCbeta2 by endotoxin plays a role in the adenosine A(2A) receptor-mediated switch of macrophages from an inflammatory to an angiogenic phenotype.
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| Grinberg S, Hasko G, Wu D, Leibovich SJ.
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| Am J Pathol 175(6):2439-53. doi: 10.2353/ajpath.2009.090290. Epub 2009 Oct 22.
2009
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7 | PLCB2, PLCB3
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| Phospholipase cbeta is critical for T cell chemotaxis.
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| Bach TL, Chen QM, Kerr WT, Wang Y, Lian L, Choi JK, Wu D, Kazanietz MG, Koretzky GA, Zigmond S, Abrams CS.
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| J Immunol 179(4):2223-7.
2007
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8 | PLCB2
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| Alternative splice variants of phospholipase C-beta2 are expressed in platelets: effect on Galphaq-dependent activation and localization.
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| Sun L, Mao G, Kunapuli SP, Dhanasekaran DN, Rao AK.
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| Platelets 18(3):217-23.
2007
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9 | PLCB2
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| PLC-beta2 activity on actin-associated polyphosphoinositides promotes migration of differentiating tumoral myeloid precursors.
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| Brugnoli F, Bavelloni A, Benedusi M, Capitani S, Bertagnolo V.
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| Cell Signal 19(8):1701-12. Epub 2007 Mar 28.
2007
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10 | PLCB2
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| Phospholipase C-beta 2 promotes mitosis and migration of human breast cancer-derived cells.
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| Bertagnolo V, Benedusi M, Brugnoli F, Lanuti P, Marchisio M, Querzoli P, Capitani S.
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| Carcinogenesis 28(8):1638-45. Epub 2007 Apr 11.
2007
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11 | PLCB2
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| PLC-beta2 is highly expressed in breast cancer and is associated with a poor outcome: a study on tissue microarrays.
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| Bertagnolo V, Benedusi M, Querzoli P, Pedriali M, Magri E, Brugnoli F, Capitani S.
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| Int J Oncol 28(4):863-72.
2006
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12 | PLCB2
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| Phospholipase Cbeta2 binds to and inhibits phospholipase Cdelta1.
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| Guo Y, Rebecchi M, Scarlata S.
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| J Biol Chem 280(2):1438-47. Epub 2004 Oct 27. 2005
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13 | PLCB2
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| Assignment of human PLCB2 encoding PLC beta2 to human chromosome 15q15 by fluorescence in situ hybridization.
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| Park SH, et al.
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| Cytogenet Cell Genet 83 : 48-49. 1998
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14 | PLCB2
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| Cloning, sequencing, expression, and Gq-independent activation of phospholipase C-beta 2.
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| Park D, et al.
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| J Biol Chem 267 : 16048-16055. 1992
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