| 1 | PLAU, STING1
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| Proteomics analysis uncovers plasminogen activator PLAU as a target of the STING pathway for suppression of cancer cell migration and invasion.
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| Tan J, Ge Y, Zhang M, Ding M.
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| J Biol Chem. Jan;299(1):102779. doi: 10.1016/j.jbc.2022.102779. Epub 2022 Dec 7. 2023
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| 2 | PLAU
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| Functional Validation of the Putative Oncogenic Activity of PLAU.
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| Sarno F, Goubert D, Logie E, Rutten MGS, Koncz M, Deben C, Niemarkt AE, Altucci L, Verschure PJ, Kiss A, Berghe WV, Rots MG.
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| Biomedicines. Dec 30;11(1):102. doi: 10.3390/biomedicines11010102. 2022
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| 3 | MMD, PLAU
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| p53 loss activates prometastatic secretory vesicle biogenesis in the Golgi.
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| Tan X, Banerjee P, Shi L, Xiao GY, Rodriguez BL, Grzeskowiak CL, Liu X, Yu J, Gibbons DL, Russell WK, Creighton CJ, Kurie JM.
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| Sci Adv. Jun 18;7(25):eabf4885. doi: 10.1126/sciadv.abf4885. 2021
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| 4 | PLAU
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| PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma. 2021 PMID:
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| Chen G, Sun J, Xie M, Yu S, Tang Q, Chen L.
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| Front Genet. May 20;12:651882. doi: 10.3389/fgene.2021.651882. 2021
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| 5 | IL6, JUN, PLAU
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| Identification of the key genes associated with neuropathic pain
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| Liu H, Xia T, Xu F, Ma Z, Gu X.
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| Mol Med Rep. May;17(5):6371-6378. doi: 10.3892/mmr.2018.8718. Epub 2018 Mar 9. 2018
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| 6 | HMGA1, PLAU, SERPINE1
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| HMGA1 regulates the Plasminogen activation system in the secretome of breast cancer cells
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| Resmini G, Rizzo S, Franchin C, Zanin R, Penzo C, Pegoraro S, Ciani Y, Piazza S, Arrigoni G, Sgarra R, Manfioletti G
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| Sci Rep. Sep 18;7(1):11768. doi: 10.1038/s41598-017-11409-4. 2017
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| 7 | PLAU
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| PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells.
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| He F, Chen H, Probst-Kepper M, Geffers R, Eifes S, Del Sol A, Schughart K, Zeng AP, Balling R.
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| Mol Syst Biol 8:624. doi: 10.1038/msb.2012.56.
2012
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| 8 | PLAU, RRM2
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| Regulation of urokinase expression at the posttranscription level by lung epithelial cells.
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| Shetty SK, Marudamuthu AS, Abernathy D, Shetty RS, Shetty P, Fu J, Idell S, Bhandary YP, Ji H, Liu MC, Shetty S.
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| Biochemistry 51(1):205-13. doi: 10.1021/bi201293x. Epub 2011 Dec 23.
2012
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| 9 | PLAU
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| Association of putative functional variants in the PLAU gene and the PLAUR gene with myocardial infarction.
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| Xu J, Li W, Bao X, Ding H, Chen J, Zhang W, Sun K, Wang J, Wang X, Wang H, Yu H, Song W, Ma W, Zhang L, Wang C, Wang D, Hui R.
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| Clin Sci (Lond) 119(8):353-9. doi: 10.1042/CS20100151.
2010
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| 10 | BRMS1, PLAU
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| BRMS1 contributes to the negative regulation of uPA gene expression through recruitment of HDAC1 to the NF-kappaB binding site of the uPA promoter.
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| Cicek M, Fukuyama R, Cicek MS, Sizemore S, Welch DR, Sizemore N, Casey G.
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| Clin Exp Metastasis 26(3):229-37. doi: 10.1007/s10585-009-9235-1. Epub 2009 Jan 23.
2009
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| 11 | PLAU
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| The urokinase-type plasminogen activator polymorphism PLAU_1 is a risk factor for APOE-epsilon4 non-carriers in the Italian Alzheimer's disease population and does not affect the plasma Abeta(1-42) level.
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| Pesaresi M, Batelli S, Prato F, Polito L, Lovati C, Scarpini E, Quadri P, Mariani C, Albani D, Forloni G.
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| Neurobiol Dis 25(3):609-13. Epub 2006 Dec 15.
2007
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| 12 | PLAU
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| A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimer's disease.
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| Riemenschneider M, Konta L, Friedrich P, Schwarz S, Taddei K, Neff F, Padovani A, Kolsch H, Laws SM, Klopp N, Bickeboller H, Wagenpfeil S, Mueller JC, Rosenberger A, Diehl-Schmid J, Archetti S, Lautenschlager N, Borroni B, Muller U, Illig T, Heun R, Egensperger R, Schlegel J, Forstl H, Martins RN, Kurz A.
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| Hum Mol Genet 15(16):2446-56. Epub 2006 Jul 6. 2006
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| 13 | ETS1, MMP1, PLAU, SP100
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| SP100 inhibits ETS1 activity in primary endothelial cells.
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| Yordy JS, Moussa O, Pei H, Chaussabel D, Li R, Watson DK.
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| Oncogene 24(5):916-31.
2005
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| 14 | PLAU
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| Urokinase is required for the formation of mactinin, an alpha-actinin fragment that promotes monocyte/macrophage maturation.
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| Luikart S, Masri M, Wahl D, Hinkel T, Beck JM, Gyetko MR, Gupta P, Oegema T.
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| Biochim Biophys Acta 1591(1-3):99-107. 2002
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| 15 | PLAU
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| Identification of a novel nuclear factor-kappaB sequence involved in expression of urokinase-type plasminogen activator receptor.
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| Wang Y, Dang J, Wang H, Allgayer H, Murrell GA, Boyd D.
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| Eur J Biochem 267(11):3248-54. 2000
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| 16 | PLAU
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| The human urokinase-plasminogen activator gene (PLAU) is located on chromosome 10q24 centromeric to the HOX11 gene.
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| Stein PM, et al.
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| Genomics 16 : 301-302. 1993
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| 17 | PLAT, PLAU
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| Mapping of tissue plasminogen activator (PLAT) to chromosome 8 and urokinase (PLAU) to chromosome 10 in humans.
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| Rajput B, et al.
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| (HGM8) Cytogenet Cell Genet 40 : 728-729. 1985
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| 18 | PLAU
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| Chromosomal locations of human tissue plasminogen activator and urokinase genes.
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| Rajput B, et al.
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| Science 230 : 672-674. 1985
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| 19 | PLAU
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| Human urokinase gene is located on the long arm of chromosome 10.
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| Tripputi P, et al.
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| Proc Natl Acad Sci U S A 82 : 4448-4452. 1985
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| 20 | PLAU
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| BamHI RFLP linked to the human urokinase gene.
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| Sebastio G, et al.
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| Nucleic Acids Res 13 : 5404. 1985
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