| 1 | FXR1, PKP1, PKP2, PKP3
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| Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins.
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| Fischer-Kešo R, Breuninger S, Hofmann S, Henn M, Röhrig T, Ströbel P, Stoecklin G, Hofmann I.
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| Mol Cell Biol 34(23):4244-56. doi: 10.1128/MCB.00766-14. Epub 2014 Sep 15.
2014
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| 2 | EBSPD, PKP1
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| A plakophilin-1 gene mutation in an egyptian family with ectodermal dysplasia-skin fragility syndrome.
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| Abdalla EM, Has C.
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| Mol Syndromol 5(6):304-6. doi: 10.1159/000369267. Epub 2014 Nov 28.
2014
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| 3 | PKP1
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| Plakophilin-1 protects keratinocytes from pemphigus vulgaris IgG by forming calcium-independent desmosomes.
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| Tucker DK, Stahley SN, Kowalczyk AP.
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| J Invest Dermatol 134(4):1033-43. doi: 10.1038/jid.2013.401. Epub 2013 Sep 20.
2014
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| 4 | PKP1
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| Aberrantly methylated PKP1 in the progression of Barrett's esophagus to esophageal adenocarcinoma.
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| Kaz AM, Luo Y, Dzieciatkowski S, Chak A, Willis JE, Upton MP, Leidner RS, Grady WM.
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| Genes Chromosomes Cancer 51(4):384-93. doi: 10.1002/gcc.21923. Epub 2011 Dec 14.
2012
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| 5 | EIF4A1, PKP1
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| Plakophilin 1 stimulates translation by promoting eIF4A1 activity.
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| Wolf A, Krause-Gruszczynska M, Birkenmeier O, Ostareck-Lederer A, Hüttelmaier S, Hatzfeld M.
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| J Cell Biol 188(4):463-71. doi: 10.1083/jcb.200908135. Epub 2010 Feb 15.
2010
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| 6 | PKP1, PKP2
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| Plakophilin-1 localizes to the nucleus and interacts with single-stranded DNA.
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| Sobolik-Delmaire T, Reddy R, Pashaj A, Roberts BJ, Wahl JK 3rd.
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| J Invest Dermatol 130(11):2638-46. doi: 10.1038/jid.2010.191. Epub 2010 Jul 8.
2010
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| 7 | PKP1
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| Ectodermal dysplasia-skin fragility syndrome.
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| McGrath JA, Mellerio JE.
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| Dermatol Clin 28(1):125-9. doi: 10.1016/j.det.2009.10.014. Review.
2010
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| 8 | EBSPD, PKP1
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| Novel truncating mutations in PKP1 and DSP cause similar skin phenotypes in two Brazilian families.
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| Tanaka A, Lai-Cheong JE, Café ME, Gontijo B, Salomão PR, Pereira L, McGrath JA.
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| Br J Dermatol 160(3):692-7. doi: 10.1111/j.1365-2133.2008.08900.x. Epub 2008 Oct 21.
2009
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| 9 | DSP, PKP1
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| Carboxyl terminus of Plakophilin-1 recruits it to plasma membrane, whereas amino terminus recruits desmoplakin and promotes desmosome assembly.
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| Sobolik-Delmaire T, Katafiasz D, Wahl JK 3rd.
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| J Biol Chem 281(25):16962-70. Epub 2006 Apr 21.
2006
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| 10 | EBSPD, PKP1
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| Compound heterozygosity for new splice site mutations in the plakophilin 1 gene (PKP1) in a Chinese case of ectodermal dysplasia-skin fragility syndrome.
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| Zheng R, Bu DF, Zhu XJ.
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| Acta Derm Venereol 85(5):394-9. 2005
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| 11 | EBSPD, PKP1
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| Clinical and molecular significance of splice site mutations in the plakophilin 1 gene in patients with ectodermal dysplasia-skin fragility syndrome.
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| Wessagowit V, McGrath JA.
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| Acta Derm Venereol 85(5):386-8. No abstract available. 2005
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| 12 | PKP1
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| Lack of plakophilin 1 increases keratinocyte migration and reduces desmosome stability.
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| South AP, Wan H, Stone MG, Dopping-Hepenstal PJ, Purkis PE, Marshall JF, Leigh IM, Eady RA, Hart IR, McGrath JA.
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| J Cell Sci 116(Pt 16):3303-14. Epub 2003 Jul 2. 2003
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| 13 | EBSPD, PKP1
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| Genomic amplification of the human plakophilin 1 gene and detection of a new mutation in ectodermal dysplasia/skin fragility syndrome.
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| Whittock NV, Haftek M, Angoulvant N, Wolf F, Perrot H, Eady RA, McGrath JA.
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| J Invest Dermatol 115(3):368-74. 2000
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| 14 | PKP1
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| Physical characterization of plakophilin 1 reconstituted with and without zinc.
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| Hofmann I, Mucke N, Reed J, Herrmann H, Langowski J.
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| Eur J Biochem 267(14):4381-9. 2000
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| 15 | EBSPD, PKP1
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| Skin fragility and hypohidrotic ectodermal dysplasia resulting from ablation of plakophilin 1.
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| McGrath JA, et al.
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| Br J Dermatol 140(2):297-307. 1999
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| 16 | EBSPD, PKP1
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| The head domain of plakophilin-1 binds to desmoplakin and enhances its recruitment to desmosomes. Implications for cutaneous disease.
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| Kowalczyk AP, et al.
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| J Biol Chem 274(26):18145-8. 1999
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| 17 | PKP1, PKP2, PKP3
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| Plakophilin 3--a novel cell-type-specific desmosomal plaque protein.
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| Schmidt A, et al.
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| Differentiation 64(5):291-306 1999
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| 18 | ARVCF, CTNND1, CTNND2, PKP4, PKP1, PKP2
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| Chromosomal mapping of human armadillo genes belonging to the p120ctn/plakophilin subfamily.
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| BonnŽ S, et al.
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| Genomics 51 : 452-454. 1998
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| 19 | JUP, PKP1
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| The plakophilin 1 (PKP1) and plakoglobin (JUP) genes map to human chromosomes 1q and 17, respectively.
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| Cowley CM, Simrak D, Spurr NK, Arnemann J, Buxton RS.
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| Hum Genet 100(3-4):486-8. 1997
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| 20 | EBSPD, PKP1
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| Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome.
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| McGrath JA, McMillan JR, Shemanko CS, Runswick SK, Leigh IM, Lane EB, Garrod DR, Eady RA.
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| Nat Genet 17(2):240-4. 1997
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| 21 | PKP1
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| Band 6 protein, a major constituent of desmosomes from stratified epithelia, is a novel member of the armadillo multigene family.
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| Hatzfeld M, et al.
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| J Cell Sci 107 : 2259-2270. 1994
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| 22 | APC, CTNNB1, CTNND1, JUP, KPNA3, ARVCF, CTNND2, KPNA2, PKP4, PKP1, PKP2, SPAG6
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| A repeating amino acid motif shared by proteins with diverse cellular roles.
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| Peifer M, et al.
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| Cell 76(5):789-91. No abstract available 1994
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