1 | PKD1L3, pKD2L1
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| A PKD1L3 splice variant in taste buds is not cleaved at the G protein-coupled receptor proteolytic site.
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| Kashyap P, Ng C, Wang Z, Li B, Arif Pavel M, Martin H, Yu Y.
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| Biochem Biophys Res Commun. May 14;512(4):812-818. doi: 10.1016/j.bbrc.2019.03.099. Epub 2019 Mar 27 2019
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2 | PKD2L1
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| Deficiency of PKD2L1 (TRPP3) Exacerbates Pathological Cardiac Hypertrophy by Augmenting NCX1-Mediated Mitochondrial Calcium Overload.
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| Lu Z, Cui Y, Wei X, Gao P, Zhang H, Wei X, Li Q, Sun F, Yan Z, Zheng H, Yang G, Liu D, Zhu Z.
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| Cell Rep. Aug 7;24(6):1639-1652. doi: 10.1016/j.celrep.2018.07.022 2018
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3 | PKD1L3, PKD2L1
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| Identification of clustered phosphorylation sites in PKD2L1: how PKD2L1 channel activation is regulated by cyclic adenosine monophosphate signaling pathway.
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| Park EYJ, Kwak M, Ha K, So I.
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| Pflugers Arch. Mar;470(3):505-516. doi: 10.1007/s00424-017-2095-7. Epub 2017 Dec 11 2018
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4 | PKD1L3, PKD2L1
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| A novel PKD2L1 C-terminal domain critical for trimerization and channel function.
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| Zheng W, Hussein S, Yang J, Huang J, Zhang F, Hernandez-Anzaldo S, Fernandez-Patron C, Cao Y, Zeng H, Tang J, Chen XZ.
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| Sci Rep. Mar 30;5:9460. doi: 10.1038/srep09460. 2015
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5 | PKD1L1, PKD2L1
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| Direct recording and molecular identification of the calcium channel of primary cilia.
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| DeCaen PG, Delling M, Vien TN, Clapham DE.
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| Nature 504(7479):315-8. doi: 10.1038/nature12832. Erratum in: Nature. 2014 Sep 11;513(7517):266.
2013
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6 | GLI1, GLI2, PKD1L1, PKD2L1
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| Primary cilia are specialized calcium signalling organelles.
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| Delling M, DeCaen PG, Doerner JF, Febvay S, Clapham DE.
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| Nature 504(7479):311-4. doi: 10.1038/nature12833.
2013
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7 | PKD2L1, RACK1
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| Receptor for activated C kinase 1 (RACK1) inhibits function of transient receptor potential (TRP)-type channel Pkd2L1 through physical interaction.
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| Yang J, Wang Q, Zheng W, Tuli J, Li Q, Wu Y, Hussein S, Dai XQ, Shafiei S, Li XG, Shen PY, Tu JC, Chen XZ.
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| J Biol Chem. Feb 24;287(9):6551-61. doi: 10.1074/jbc.M111.305854. Epub 2011 Dec 15 2012
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8 | PKD2L1
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| Crystal structure and characterization of coiled-coil domain of the transient receptor potential channel PKD2L1.
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| Molland KL, Paul LN, Yernool DA.
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| Biochim Biophys Acta. Mar;1824(3):413-21. doi: 10.1016/j.bbapap.2011.12.002. Epub 2011 Dec 13. 2012
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9 | PKD1L3, PKD2L1
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| Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex.
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| Yu Y, Ulbrich MH, Li MH, Dobbins S, Zhang WK, Tong L, Isacoff EY, Yang J.
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| Nat Commun. 3:1252. doi: 10.1038/ncomms2257 2012
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10 | PKD1L3, PKD2L1
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| Crystal structure and characterization of coiled-coil domain of the transient receptor potential channel PKD2L1.
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| Molland KL, Paul LN, Yernool DA.
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| Biochim Biophys Acta. Mar;1824(3):413-21. doi: 10.1016/j.bbapap.2011.12.002. Epub 2011 Dec 13. 2012
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11 | PKD1L3, PKD2L1
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| Molecular evolution of candidate sour taste receptor gene PKD1L3 in mammals.
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| Chen D, Li P, Guo W, Ye F, Wu J, Wei D, Guo Z, Ye C.
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| Genome Nov;54(11):890-7. doi: 10.1139/g11-057. Epub 2011 Oct 20 2011
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12 | PKD2, PKD2L1
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| Identification of the structural motif responsible for trimeric assembly of the C-terminal regulatory domains of polycystin channels PKD2L1 and PKD2.
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| Molland KL, Narayanan A, Burgner JW, Yernool DA.
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| Biochem J. 429(1):171-83. 2010
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13 | PKD1L3, PKD2L1
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| Off-response property of an acid-activated cation channel complex PKD1L3-PKD2L1.
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| Inada H, Kawabata F, Ishimaru Y, Fushiki T, Matsunami H, Tominaga M.
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| EMBO Rep 9(7):690-7. Epub 2008 Jun 6.
2008
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14 | PKD2L1, PKD1L3
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| Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor.
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| Ishimaru Y, Inada H, Kubota M, Zhuang H, Tominaga M, Matsunami H.
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| Proc Natl Acad Sci U S A 103(33):12569-74. Epub 2006 Aug 4. 2006
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15 | PKD2L1, TNNI1, TNNI2
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| Troponin I binds polycystin-L and inhibits its calcium-induced channel activation.
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| Li Q, Liu Y, Shen PY, Dai XQ, Wang S, Smillie LB, Sandford R, Chen XZ.
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| Biochemistry 42(24):7618-25. 2003
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16 | NPHS2, PKD2L1, SRN1
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| Tissue and cellular localization of a novel polycystic kidney disease-like gene product, polycystin-L.
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| Basora N, Nomura H, Berger UV, Stayner C, Guo L, Shen X, Zhou J.
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| J Am Soc Nephrol 13(2):293-301. 2002
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17 | PKD2L1
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| The human polycystic kidney disease 2-like (PKDL) gene: exon/intron structure and evidence for a novel splicing mechanism.
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| Guo L, Chen M, Basora N, Zhou J.
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| Mamm Genome 11(1):46-50. 2000
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18 | PKD2L1
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| Polycystin-L is a calcium-regulated cation channel permeable to calcium ions.
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| Chen XZ, et al.
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| Nature 401(6751):383-6. 1999
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19 | PKD, PKD1, PKD2, PKD2L1, PKD2L2, PKDREJ
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| Genes homologous to the autosomal dominant polycystic kidney disease genes.
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| Veldhuisen B, Spruit L, Dauwerse HG, Breuning MH, Peters DJ.
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| Eur J Hum Genet 7(8):860-72 1999
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20 | PKD2L1
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| Identification of PKDL, a novel polycystic kidney disease 2-like gene whose murine homologue is deleted in mice with kidney and retinal defects.
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| Nomura H, Turco AE, Pei Y, Kalaydjieva L, Schiavello T, Weremowicz S, Ji W, Morton CC, Meisler M, Reeders ST, Zhou J.
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| J Biol Chem 273 : 25967-25973. 1998
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21 | PKD2L1
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| Identification of PKD2L, a human PKD2-related gene : tissue-specific expression and mapping to chromosome 10q25.
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| Wu G, Hayashi T, Park JH, Dixit M, Reynolds DM, Li L, Maeda Y, Cai Y, Coca-Prados M, Somlo S.
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| Genomics 54 : 564-568. 1998
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22 | PKD1L3, PKD2L1
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| Influx-Operated Ca(2+) Entry via PKD2-L1 and PKD1-L3 Channels Facilitates Sensory Responses to Polymodal Transient Stimuli.
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| Hu M, Liu Y, Wu J, Liu X.
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