| 1 | CTPP2, PITX3
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| A novel mutation in the OAR domain of PITX3 associated with congenital posterior subcapsular cataract.
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| Fan Q, Li D, Cai L, Qiu X, Zhao Z, Wu J, Yang J, Lu Y.
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| BMC Med Genet 20(1):42. doi: 10.1186/s12881-019-0782-2.
2019
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| 2 | LMO3, PITX3
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| Specificity of Pitx3-Dependent Gene Regulatory Networks in Subsets of Midbrain Dopamine Neurons.
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| Bifsha P, Balsalobre A, Drouin J.
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| Mol Neurobiol 54(7):4921-4935. doi: 10.1007/s12035-016-0040-y. Epub 2016 Aug 11.
2017
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| 3 | PITX3
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| PITX3 genotype and risk of dementia in Parkinson's disease: A population-based study.
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| Bäckström D, Domellöf ME, Granåsen G, Linder J, Mayans S, Elgh E, Mo SJ, Forsgren L.
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| J Neurol Sci 381:278-284. doi: 10.1016/j.jns.2017.08.3259. Epub 2017 Sep 1.
2017
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| 4 | EN1, PITX3
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| Pitx3 and En1 determine the size and molecular programming of the dopaminergic neuronal pool.
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| Kouwenhoven WM, von Oerthel L, Smidt MP.
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| PLoS One 12(8):e0182421. doi: 10.1371/journal.pone.0182421. eCollection 2017.
2017
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| 5 | PITX3
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| PITX3 DNA methylation is an independent predictor of overall survival in patients with head and neck squamous cell carcinoma.
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| Sailer V, Holmes EE, Gevensleben H, Goltz D, Dröge F, Franzen A, Dietrich J, Kristiansen G, Bootz F, Schröck A, Dietrich D.
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| Clin Epigenetics 9:12. doi: 10.1186/s13148-017-0317-7. eCollection 2017.
2017
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| 6 | PITX3
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| Differences in the spatiotemporal expression and epistatic gene regulation of the mesodiencephalic dopaminergic precursor marker PITX3 during chicken and mouse development.
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| Klafke R, Prem Anand AA, Wurst W, Prakash N, Wizenmann A.
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| Development 143(4):691-702. doi: 10.1242/dev.126748. Epub 2016 Jan 11.
2016
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| 7 | PITX3
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| Pitx3 deficiency produces decreased dopamine signaling and induces motor deficits in Pitx3(-/-) mice.
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| Le W, Zhang L, Xie W, Li S, Dani JA.
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| Neurobiol Aging 36(12):3314-3320. doi: 10.1016/j.neurobiolaging.2015.08.012. Epub 2015 Aug 20.
2015
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| 8 | LMX1A, NR4A2, PITX3
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| Functional roles of Nurr1, Pitx3, and Lmx1a in neurogenesis and phenotype specification of dopamine neurons during in vitro differentiation of embryonic stem cells.
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| Hong S, Chung S, Leung K, Hwang I, Moon J, Kim KS.
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| Stem Cells Dev 23(5):477-87. doi: 10.1089/scd.2013.0406. Epub 2013 Dec 4.
2014
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| 9 | PITX3
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| Expression of truncated PITX3 in the developing lens leads to microphthalmia and aphakia in mice.
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| Wada K, Matsushima Y, Tada T, Hasegawa S, Obara Y, Yoshizawa Y, Takahashi G, Hiai H, Shimanuki M, Suzuki S, Saitou J, Yamamoto N, Ichikawa M, Watanabe K, Kikkawa Y.
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| PLoS One 9(10):e111432. doi: 10.1371/journal.pone.0111432. eCollection 2014.
2014
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| 10 | PITX2, PITX3
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| Redox regulation by Pitx2 and Pitx3 is critical for fetal myogenesis.
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| L'honoré A, Commère PH, Ouimette JF, Montarras D, Drouin J, Buckingham M.
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| Dev Cell 29(4):392-405. doi: 10.1016/j.devcel.2014.04.006. Erratum in: Dev Cell. 2016 Dec 19;39(6):756.
2014
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| 11 | PITX3
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| Association between PITX3 promoter polymorphism and risk of Parkinson's disease: the impact of ethnicity and onset age.
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| Qiu G, Fu C, Liang GH.
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| Neurosci Lett 561:128-33. doi: 10.1016/j.neulet.2013.12.054. Epub 2014 Jan 3.
2014
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| 12 | FOXE3, PITX3
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| Pitx3 directly regulates Foxe3 during early lens development.
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| Ahmad N, Aslam M, Muenster D, Horsch M, Khan MA, Carlsson P, Beckers J, Graw J.
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| Int J Dev Biol 57(9-10):741-51. doi: 10.1387/ijdb.130193jg.
2013
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| 13 | EN1, PITX3
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| Specification of dopaminergic subsets involves interplay of En1 and Pitx3.
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| Veenvliet JV, Dos Santos MT, Kouwenhoven WM, von Oerthel L, Lim JL, van der Linden AJ, Koerkamp MJ, Holstege FC, Smidt MP.
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| Development 140(16):3373-84. doi: 10.1242/dev.094565. Epub 2013 Jul 17. Erratum in: Development. 2013 Oct;140(19):4116.
2013
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| 14 | PITX3
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| The transcription factor Pitx3 is expressed selectively in midbrain dopaminergic neurons susceptible to neurodegenerative stress.
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| Luk KC, Rymar VV, van den Munckhof P, Nicolau S, Steriade C, Bifsha P, Drouin J, Sadikot AF.
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| J Neurochem 125(6):932-43. doi: 10.1111/jnc.12160. Epub 2013 Mar 6.
2013
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| 15 | NR4A2, PITX3
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| Decreased NURR1 and PITX3 gene expression in Chinese patients with Parkinson's disease.
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| Liu H, Wei L, Tao Q, Deng H, Ming M, Xu P, Le W.
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| Eur J Neurol 19(6):870-5. doi: 10.1111/j.1468-1331.2011.03644.x. Epub 2012 Feb 6.
2012
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| 16 | PITX3
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| A novel 1-bp deletion in PITX3 causing congenital posterior polar cataract.
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| Berry V, Francis PJ, Prescott Q, Waseem NH, Moore AT, Bhattacharya SS.
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| Mol Vis. 17:1249-53. 2011
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| 17 | PITX3
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| Pitx3 is a critical mediator of GDNF-induced BDNF expression in nigrostriatal dopaminergic neurons.
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| Peng C, Aron L, Klein R, Li M, Wurst W, Prakash N, Le W.
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| J Neurosci 31(36):12802-15. doi: 10.1523/JNEUROSCI.0898-11.2011.
2011
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| 18 | FOXP1, PITX3
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| FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3.
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| Konstantoulas CJ, Parmar M, Li M.
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| J Neurochem 113(4):836-47. doi: 10.1111/j.1471-4159.2010.06650.x. Epub 2010 Feb 19.
2010
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| 19 | PITX3
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| Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression.
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| Jacobs FM, van Erp S, van der Linden AJ, von Oerthel L, Burbach JP, Smidt MP.
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| Development. 136(4):531-40. 2009
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| 20 | PITX3
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| A muscle-specific promoter directs Pitx3 gene expression in skeletal muscle cells.
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| Coulon V, L'HonorŽ A, Ouimette JF, Dumontier E, van den Munckhof P, Drouin J.
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| J Biol Chem 282(45):33192-200. Epub 2007 Sep 11. 2007
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| 21 | NR4A2, PITX3
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| Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype.
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| Martinat C, Bacci JJ, Leete T, Kim J, Vanti WB, Newman AH, Cha JH, Gether U, Wang H, Abeliovich A.
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| Proc Natl Acad Sci U S A [Epub ahead of print] 2006
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| 22 | PITX3, CTPP2
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| Heterozygous and homozygous mutations in PITX3 in a large Lebanese family with posterior polar cataracts and neurodevelopmental abnormalities.
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| Bidinost C, Matsumoto M, Chung D, Salem N, Zhang K, Stockton DW, Khoury A, Megarbane A, Bejjani BA, Traboulsi EI.
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| Invest Ophthalmol Vis Sci 47(4):1274-80. 2006
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| 23 | PITX3, CTPP2
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| Posterior polar cataract is the predominant consequence of a recurrent mutation in the PITX3 gene.
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| Addison PK, Berry V, Ionides AC, Francis PJ, Bhattacharya SS, Moore AT.
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| Br J Ophthalmol 89(2):138-41. 2005
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| 24 | ASMD2, PITX3
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| A novel homeobox gene PITX3 is mutated in families with autosomal-dominant cataracts and ASMD.
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| Semina EV, et al.
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| Nat Genet 19 : 167-170. 1998
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| 25 | PITX3
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| Isolation of a new homeobox gene belonging to the Pitx/Rieg family : expression during lens development and mapping to the aphakia region on mouse chromosome 19.
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| Semina EV, et al.
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| Hum Mol Genet 6 : 2109-2116. 1997
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