| 1 | PITX2, TFAP2A
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| A Functional Variant Associated with Atrial Fibrillation Regulates PITX2c Expression through TFAP2a.
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| Ye J, Tucker NR, Weng LC, Clauss S, Lubitz SA, Ellinor PT.
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| Am J Hum Genet 99(6):1281-1291. doi: 10.1016/j.ajhg.2016.10.001.
2016
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| 2 | PITX2
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| PITX2 Modulates Atrial Membrane Potential and the Antiarrhythmic Effects of Sodium-Channel Blockers.
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| Syeda F, Holmes AP, Yu TY, Tull S, Kuhlmann SM, Pavlovic D, Betney D, Riley G, Kucera JP, Jousset F, de Groot JR, Rohr S, Brown NA, Fabritz L, Kirchhof P.
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| J Am Coll Cardiol 68(17):1881-1894. doi: 10.1016/j.jacc.2016.07.766.
2016
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| 3 | LEF1, PITX2, SOX2
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| Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal.
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| Sun Z, Yu W, Sanz Navarro M, Sweat M, Eliason S, Sharp T, Liu H, Seidel K, Zhang L, Moreno M, Lynch T, Holton NE, Rogers L, Neff T, Goodheart MJ, Michon F, Klein OD, Chai Y, Dupuy A, Engelhardt JF, Chen Z, Amendt BA.
|
| Development 143(22):4115-4126.
2016
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| 4 | PITX2
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| PITX2 loss-of-function mutation contributes to tetralogy of Fallot.
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| Sun YM, Wang J, Qiu XB, Yuan F, Xu YJ, Li RG, Qu XK, Huang RT, Xue S, Yang YQ.
|
| Gene 577(2):258-64. doi: 10.1016/j.gene.2015.12.001.
2016
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| 5 | PITX2
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| Pitx2 impairs calcium handling in a dose-dependent manner by modulating Wnt signalling.
|
| Lozano-Velasco E, Hernández-Torres F, Daimi H, Serra SA, Herraiz A, Hove-Madsen L, Aránega A, Franco D.
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| Cardiovasc Res 109(1):55-66. doi: 10.1093/cvr/cvv207.
2016
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| 6 | BARX1, ISL1, PITX1, PITX2, SIX2
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| Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1.
|
| Jayewickreme CD, Shivdasani RA.
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| Dev Biol 405(1):21-32. doi: 10.1016/j.ydbio.2015.05.024. Epub 2015 Jun 6.
2015
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| 7 | PITX2
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| Expression patterns and immunohistochemical localization of PITX2B transcription factor in the developing mouse heart.
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| Hernandez-Torres F, Franco D, Aranega AE, Navarro F.
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| Int J Dev Biol 59(4-6):247-54. doi: 10.1387/ijdb.140224fh.
2015
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| 8 | ENPEP, PITX2
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| Long-range regulatory interactions at the 4q25 atrial fibrillation risk locus involve PITX2c and ENPEP.
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| Aguirre LA, Alonso ME, Badía-Careaga C, Rollán I, Arias C, Fernández-Mińán A, López-Jiménez E, Aránega A, Gómez-Skarmeta JL, Franco D, Manzanares M.
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| BMC Biol 13:26. doi: 10.1186/s12915-015-0138-0.
2015
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| 9 | PITX2
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| Axial level-specific regulation of neuronal development: lessons from PITX2.
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| Waite MR, Martin DM.
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| J Neurosci Res 93(2):195-8. doi: 10.1002/jnr.23471. Review.
2015
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| 10 | DEPDC1B, PITX2
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| Identification of the GTPase-activating protein DEP domain containing 1B (DEPDC1B) as a transcriptional target of Pitx2
|
| Wu D, Zhu X, Jimenez-Cowell K, Mold AJ, Sollecito CC, Lombana N, Jiao M, Wei Q.
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| Exp Cell Res. Apr 10;333(1):80-92. doi: 10.1016/j.yexcr.2015.02.008. Epub 2015 Feb 19. P 2015
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| 11 | GDF1, PITX2
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| The transcription factor Pitx2 positions the embryonic axis and regulates twinning.
|
| Torlopp A, Khan MA, Oliveira NM, Lekk I, Soto-Jiménez LM, Sosinsky A, Stern CD.
|
| Elife 3:e03743. doi: 10.7554/eLife.03743.
2014
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| 12 | PITX2
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| DNA methylation of PITX2 predicts poor survival in men with prostate cancer.
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| Vasiljević N, Ahmad AS, Carter PD, Fisher G, Berney DM, Foster CS, Cuzick J, Lorincz AT.
|
| Biomark Med 8(9):1143-50. doi: 10.2217/bmm.14.41.
2014
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| 13 | FOXC1, PITX2
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| Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease.
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| French CR, Seshadri S, Destefano AL, Fornage M, Arnold CR, Gage PJ, Skarie JM, Dobyns WB, Millen KJ, Liu T, Dietz W, Kume T, Hofker M, Emery DJ, Childs SJ, Waskiewicz AJ, Lehmann OJ.
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| J Clin Invest 124(11):4877-81. doi: 10.1172/JCI75109.
2014
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| 14 | PITX2
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| Novel PITX2c loss-of-function mutations associated with complex congenital heart disease.
|
| Wei D, Gong XH, Qiu G, Wang J, Yang YQ.
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| Int J Mol Med 33(5):1201-8. doi: 10.3892/ijmm.2014.1689.
2014
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| 15 | MYF5, PITX2
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| Pitx2c is reactivated in the failing myocardium and stimulates myf5 expression in cultured cardiomyocytes.
|
| Torrado M, Franco D, Hernández-Torres F, Crespo-Leiro MG, Iglesias-Gil C, Castro-Beiras A, Mikhailov AT.
|
| PLoS One 9(3):e90561. doi: 10.1371/journal.pone.0090561. eCollection 2014.
2014
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| 16 | PAXIP1, PITX2
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| PITX2 associates with PTIP-containing histone H3 lysine 4 methyltransferase complex.
|
| Liu Y, Huang Y, Fan J, Zhu GZ.
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| Biochem Biophys Res Commun 444(4):634-7. doi: 10.1016/j.bbrc.2014.01.143. Epub 2014 Jan 31.
2014
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| 17 | PITX2, PITX3
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| Redox regulation by Pitx2 and Pitx3 is critical for fetal myogenesis.
|
| L'honoré A, Commčre PH, Ouimette JF, Montarras D, Drouin J, Buckingham M.
|
| Dev Cell 29(4):392-405. doi: 10.1016/j.devcel.2014.04.006. Erratum in: Dev Cell. 2016 Dec 19;39(6):756.
2014
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| 18 | LHX6, PITX2
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| The LIM homeodomain transcription factor LHX6: a transcriptional repressor that interacts with pituitary homeobox 2 (PITX2) to regulate odontogenesis.
|
| Zhang Z, Gutierrez D, Li X, Bidlack F, Cao H, Wang J, Andrade K, Margolis HC, Amendt BA.
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| J Biol Chem 288(4):2485-500. doi: 10.1074/jbc.M112.402933. Epub 2012 Dec 10.
2013
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| 19 | PITX2
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| PITX2c loss-of-function mutations responsible for congenital atrial septal defects.
|
| Yuan F, Zhao L, Wang J, Zhang W, Li X, Qiu XB, Li RG, Xu YJ, Xu L, Qu XK, Fang WY, Yang YQ.
|
| Int J Med Sci 10(10):1422-9. doi: 10.7150/ijms.6809.
2013
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| 20 | PITX2
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| Pitx2-mediated cardiac outflow tract remodeling.
|
| Ma HY, Xu J, Eng D, Gross MK, Kioussi C.
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| Dev Dyn 242(5):456-68. doi: 10.1002/dvdy.23934.
2013
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| 21 | FGF9, PITX2, TGFB1
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| Relationship between the localization of fibroblast growth factor 9 in prostate cancer cells and postoperative recurrence.
|
| Teishima J, Shoji K, Hayashi T, Miyamoto K, Ohara S, Matsubara A.
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| Prostate Cancer Prostatic Dis 15(1):8-14. doi: 10.1038/pcan.2011.48. Epub 2011 Oct 18. 2012
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| 22 | CITED2, NODAL, PITX2
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| CITED2 mutation links congenital heart defects to dysregulation of the cardiac gene VEGF and PITX2C expression.
|
| Li Q, Pan H, Guan L, Su D, Ma X.
|
| Biochem Biophys Res Commun 423(4):895-9. doi: 10.1016/j.bbrc.2012.06.099. Epub 2012 Jun 23.
2012
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| 23 | DEL6PD, FOXC1, PITX2
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| PITX2 and FOXC1 spectrum of mutations in ocular syndromes.
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| Reis LM, Tyler RC, Volkmann Kloss BA, Schilter KF, Levin AV, Lowry RB, Zwijnenburg PJ, Stroh E, Broeckel U, Murray JC, Semina EV.
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| Eur J Hum Genet 20(12):1224-33. doi: 10.1038/ejhg.2012.80. Epub 2012 May 9.
2012
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| 24 | PITX2
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| Pitx2 is an upstream activator of extraocular myogenesis and survival.
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| Zacharias AL, Lewandoski M, Rudnicki MA, Gage PJ.
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| Dev Biol 349(2):395-405. Epub 2010 Oct 28.
2011
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| 25 | PITX2, WDR5
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| WD repeat-containing protein 5, a ubiquitously expressed histone methyltransferase adaptor protein, regulates smooth muscle cell-selective gene activation through interaction with pituitary homeobox 2.
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| Gan Q, Thiébaud P, Thézé N, Jin L, Xu G, Grant P, Owens GK.
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| J Biol Chem 286(24):21853-64. Epub 2011 Apr 28.
2011
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| 26 | PITX2
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| PITX2 is involved in stress response in cultured human trabecular meshwork cells through regulation of SLC13A3.
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| Strungaru MH, Footz T, Liu Y, Berry FB, Belleau P, Semina EV, Raymond V, Walter MA.
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| Invest Ophthalmol Vis Sci. 52(10):7625-33. 2011
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| 27 | CDH2, PITX2, SHROOM3
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| Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis.
|
| Plageman TF Jr, Zacharias AL, Gage PJ, Lang RA.
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| Dev Biol 357(1):227-34. Epub 2011 Jun 25.
2011
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| 28 | DEL4Q, PITX2, RIEG1
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| Longitudinal observation of a patient with Rieger syndrome and interstitial deletion 4 (q25-q31.1).
|
| Moreira L, Schinzel A, Baumer A, Pinto P, Góes F, Falcăo Mde L, Barbosa AL, Riegel M.
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| Am J Med Genet A 152A(4):977-81.PMID: 20358612 2010
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| 29 | PITX2
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| Case of novel PITX2 gene mutation associated with Peters' anomaly and persistent hyperplastic primary vitreous.
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| Arikawa A, Yoshida S, Yoshikawa H, Ishikawa K, Yamaji Y, Arita RI, Ueno A, Ishibashi T.
|
| Eye (Lond). 24(2):391-3. 2010
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| 30 | PITX2, SHOX2
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| Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification.
|
| Wang J, Klysik E, Sood S, Johnson RL, Wehrens XH, Martin JF.
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| Proc Natl Acad Sci U S A 107(21):9753-8. Epub 2010 May 10.PMID: 20457925 2010
|
| 31 | AXR1, FOXC1, PITX2, RIEG1
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| Axenfeld-Rieger syndrome and spectrum of PITX2 and FOXC1 mutations.
|
| Tümer Z, Bach-Holm D.
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| Eur J Hum Genet 17(12):1527-39. Epub 2009 Jun 10.
2009
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| 32 | PAWR, PITX2, RIEG1
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| Human PRKC apoptosis WT1 regulator is a novel PITX2-interacting protein that regulates PITX2 transcriptional activity in ocular cells.
|
| Acharya M, Lingenfelter DJ, Huang L, Gage PJ, Walter MA.
|
| J Biol Chem 284(50):34829-38. Epub 2009 Oct 2.PMID: 19801652 2009
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| 33 | HMGN2, PITX2
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| Chromatin-associated HMG-17 is a major regulator of homeodomain transcription factor activity modulated by Wnt/beta-catenin signaling.
|
| Amen M, Espinoza HM, Cox C, Liang X, Wang J, Link TM, Brennan RG, Martin JF, Amendt BA.
|
| Nucleic Acids Res 36(2):462-76. Epub 2007 Nov 27. 2008
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| 34 | PITX2
|
| Pitx2 regulates gonad morphogenesis.
|
| RodrĂguez-LeĂłn J, RodrĂguez Esteban C, MartĂ M, Santiago-Josefat B, Dubova I, Rubiralta X, IzpisĂşa Belmonte JC.
|
| Proc Natl Acad Sci U S A 105(32):11242-7. Epub 2008 Aug 4.
2008
|
| 35 | FOXJ1, PITX2, RIEG1
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| Novel expression and transcriptional regulation of FoxJ1 during oro-facial morphogenesis.
|
| Venugopalan SR, Amen MA, Wang J, Wong L, Cavender AC, D'Souza RN, Akerlund M, Brody SL, Hjalt TA, Amendt BA.
|
| Hum Mol Genet 17(23):3643-54. Epub 2008 Aug 22.
2008
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| 36 | PITX2
|
| Pitx2 is functionally important in the early stages of vascular smooth muscle cell differentiation.
|
| Shang Y, Yoshida T, Amendt BA, Martin JF, Owens GK.
|
| J Cell Biol 181(3):461-73.PMID: 18458156 2008
|
| 37 | PITX2, TBX1
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| Cranial muscle defects of Pitx2 mutants result from specification defects in the first branchial arch.
|
| Shih HP, Gross MK, Kioussi C.
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| Proc Natl Acad Sci U S A 104(14):5907-12. Epub 2007 Mar 23. 2007
|
| 38 | AXR1, FOXC1, PITX2, RIEG1
|
| Genotype-phenotype correlations in Axenfeld-Rieger malformation and glaucoma patients with FOXC1 and PITX2 mutations.
|
| Strungaru MH, Dinu I, Walter MA.
|
| Invest Ophthalmol Vis Sci 48(1):228-37. 2007
|
| 39 | RIEG1, PITX2, ENPEP
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| Cytogenetically invisible microdeletions involving PITX2 in Rieger syndrome.
|
| Engenheiro E, Saraiva J, Carreira I, Ramos L, Ropers HH, Silva E, Tommerup N, Tmer Z.
|
| Clin Genet 72(5):464-70. Epub 2007 Sep 10. 2007
|
| 40 | ASMD2, ASMD3, ASMD4, ASMD5, ASMFD, AXR1, AXR2, FOXC1, IRID1, MAF, PAX6, PITX2, RIEG1, RIEG2
|
| Molecular and developmental mechanisms of anterior segment dysgenesis.
|
| Sowden JC.
|
| Eye 21(10):1310-8. Review. 2007
|
| 41 | PITX2, PLOD2
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| Involvement of Pitx2, a homeodomain transcription factor, in hypothyroidism associated reproductive disorders.
|
| Ghosh P, Saha SK, Nandi SS, Bhattacharya S, Roy SS.
|
| Cell Physiol Biochem 20(6):887-98.PMID: 17982271 2007
|
| 42 | PITX2
|
| Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch.
|
| Yashiro K, Shiratori H, Hamada H.
|
| Nature. 450(7167):180-1. 2007
|
| 43 | PITX2
|
| Pitx2c and Nkx2-5 are required for the formation and identity of the pulmonary myocardium.
|
| Mommersteeg MT, Brown NA, Prall OW, de Gier-de Vries C, Harvey RP, Moorman AF, Christoffels VM.
|
| Circ Res. 101(9):902-9. 2007
|
| 44 | DEL4Q, PITX2, RIEG1
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| Cytogenetically invisible microdeletions involving PITX2 in Rieger syndrome.
|
| Engenheiro E, Saraiva J, Carreira I, Ramos L, Ropers HH, Silva E, Tommerup N, Tümer Z.
|
| Clin Genet 72(5):464-70. Epub 2007 Sep 10.PMID: 17850355 2007
|
| 45 | RIEG1, PITX2, AXRI, FOXC1
|
| Functional interactions between FOXC1 and PITX2 underlie the sensitivity to FOXC1 gene dose in Axenfeld-Rieger syndrome and anterior segment dysgenesis.
|
| Berry FB, Lines MA, Oas JM, Footz T, Underhill DA, Gage PJ, Walter MA.
|
| Hum Mol Genet 15(6):905-19. Epub 2006 Jan 31. 2006
|
| 46 | LEFTY1, LEFTY2, PITX2, RTTN
|
| Localization of candidate regions for a novel gene for Kartagener syndrome.
|
| Gutierrez-Roelens I, Sluysmans T, Jorissen M, Amyere M, Vikkula M.
|
| Eur J Hum Genet 14(7):809-15. Epub 2006 Apr 26. 2006
|
| 47 | AXR1, FOXC1, PITX2, RIEG1
|
| Novel Mutations of FOXC1 and PITX2 in Patients with Axenfeld-Rieger Malformations.
|
| Weisschuh N, Dressler P, Schuettauf F, Wolf C, Wissinger B, Gramer E.
|
| Invest Ophthalmol Vis Sci 47(9):3846-52. 2006
|
| 48 | PITX2, RIEG1
|
| A novel PITX2 mutation and a polymorphism in a 5-generation family with Axenfeld-Rieger anomaly and coexisting Fuchs' endothelial dystrophy.
|
| Kniestedt C, Taralczak M, Thiel MA, Stuermer J, Baumer A, Gloor BP.
|
| Ophthalmology 113(10):1791.e1-8. Epub 2006 Jul 31. 2006
|
| 49 | PITX2
|
| Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development.
|
| Evans AL, Gage PJ.
|
| Hum Mol Genet 14(22):3347-59. Epub 2005 Oct 3. 2005
|
| 50 | PITX2
|
| PITX2, beta-catenin and LEF-1 interact to synergistically regulate the LEF-1 promoter.
|
| Vadlamudi U, Espinoza HM, Ganga M, Martin DM, Liu X, Engelhardt JF, Amendt BA.
|
| J Cell Sci. 118(Pt 6):1129-37. 2005
|
| 51 | CITED2, PITX2, TFAP2A, NODAL
|
| Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway.
|
| Bamforth SD, Braganca J, Farthing CR, Schneider JE, Broadbent C, Michell AC, Clarke K, Neubauer S, Norris D, Brown NA, Anderson RH, Bhattacharya S.
|
| Nat Genet 36(11):1189-96. Epub 2004 Oct 10. 2004
|
| 52 | PITX2, RIEG1
|
| Characterization and prevalence of PITX2 microdeletions and mutations in Axenfeld-Rieger malformations.
|
| Lines MA, Kozlowski K, Kulak SC, Allingham RR, Heon E, Ritch R, Levin AV, Shields MB, Damji KF, Newlin A, Walter MA.
|
| Invest Ophthalmol Vis Sci 45(3):828-33. 2004
|
| 53 | PITX2, RGDC
|
| Mutation in PITX2 is associated with ring dermoid of the cornea.
|
| Xia K, Wu L, Liu X, Xi X, Liang D, Zheng D, Cai F, Pan Q, Long Z, Dai H, Hu Z, Tang B, Zhang Z, Xia J.
|
| J Med Genet 41(12):e129. No abstract available.
2004
|
| 54 | GCM1, PITX2
|
| Interaction, cooperative promoter modulation, and renal colocalization of GCMa and Pitx2.
|
| Schubert SW, Kardash E, Khan MA, Cheusova T, Kilian K, Wegner M, Hashemolhosseini S.
|
| J Biol Chem. 279(48):50358-65. 2004
|
| 55 | NKX2-5, NPPA, PLOD1, PITX2
|
| PITX2 isoform-specific regulation of atrial natriuretic factor expression: synergism and repression with Nkx2.5.
|
| Ganga M, Espinoza HM, Cox CJ, Morton L, Hjalt TA, Lee Y, Amendt BA.
|
| J Biol Chem 278(25):22437-45. Epub 2003 Apr 11. 2003
|
| 56 | PITX1, PITX2
|
| Pitx factors are involved in basal and hormone-regulated activity of the human prolactin promoter.
|
| Quentien MH, Manfroid I, Moncet D, Gunz G, Muller M, Grino M, Enjalbert A, Pellegrini I.
|
| J Biol Chem 277(46):44408-16. Epub 2002 Sep 9. 2002
|
| 57 | CYP1B1, MYOC, PITX2
|
| Digenic inheritance of early-onset glaucoma: CYP1B1, a potential modifier gene.
|
| Vincent AL, Billingsley G, Buys Y, Levin AV, Priston M, Trope G, Williams-Lyn D, Heon E.
|
| Am J Hum Genet 70(2):448-60. 2002
|
| 58 | PITX2
|
| A molecular basis for differential developmental anomalies in Axenfeld-Rieger syndrome.
|
| Espinoza HM, Cox CJ, Semina EV, Amendt BA.
|
| Hum Mol Genet 11(7):743-53. 2002
|
| 59 | PITX2
|
| Differential regulation of gene expression by PITX2 isoforms.
|
| Cox CJ, Espinoza HM, McWilliams B, Chappell K, Morton L, Hjalt TA, Semina EV, Amendt BA.
|
| J Biol Chem 277(28):25001-10. Epub 2002 Apr 10. 2002
|
| 60 | PITX2
|
| Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development.
|
| Kioussi C, Briata P, Baek SH, Rose DW, Hamblet NS, Herman T, Ohgi KA, Lin C, Gleiberman A, Wang J, Brault V, Ruiz-Lozano P, Nguyen HD, Kemler R, Glass CK, Wynshaw-Boris A, Rosenfeld MG.
|
| Cell. 111(5):673-85. 2002
|
| 61 | PITX2
|
| Functional analyses of two newly identified PITX2 mutants reveal a novel molecular mechanism for Axenfeld-Rieger syndrome.
|
| Priston M, Kozlowski K, Gill D, Letwin K, Buys Y, Levin AV, Walter MA, Heon E.
|
| Hum Mol Genet 10(16):1631-8. 2001
|
| 62 | PITX2
|
| Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2.
|
| Shiratori H, Sakuma R, Watanabe M, Hashiguchi H, Mochida K, Sakai Y, Nishino J, Saijoh Y, Whitman M, Hamada H.
|
| Mol Cell 7(1):137-49. 2001
|
| 63 | PITX2
|
| Antagonistic regulation of Dlx2 expression by PITX2 and Msx2: implications for tooth development.
|
| Green PD, Hjalt TA, Kirk DE, Sutherland LB, Thomas BL, Sharpe PT, Snead ML, Murray JC, Russo AF, Amendt BA.
|
| Gene Expr. 9(6):265-81. 2001
|
| 64 | PITX2
|
| Variation in residual PITX2 activity underlies the phenotypic spectrum of anterior segment developmental disorders.
|
| Kozlowski K, Walter MA.
|
| Hum Mol Genet 9(14):2131-9. 2000
|
| 65 | MYL1, MYL2, MYL3, PITX2
|
| Multiple transcriptional domains, with distinct left and right components, in the atrial chambers of the developing heart.
|
| Franco D, Campione M, Kelly R, Zammit PS, Buckingham M, Lamers WH, Moorman AF.
|
| Circ Res 87(11):984-91. 2000
|
| 66 | PITX2, RIEG1
|
| Threading analysis of the Pitx2 homeodomain: Predicted structural effects of mutations causing Rieger syndrome and iridogoniodysgenesis.
|
| Banerjee-Basu S, Baxevanis AD.
|
| Hum Mutat 14(4):312-319 1999
|
| 67 | PITX2
|
| Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis.
|
| Lin CR, Kioussi C, O'Connell S, Briata P, Szeto D, Liu F, Izpisua-Belmonte JC, Rosenfeld MG.
|
| Nature 401(6750):279-82 1999
|
| 68 | PITX2, RIEG1
|
| Function of Rieger syndrome gene in left-right asymmetry and craniofacial development.
|
| Lu MF, Pressman C, Dyer R, Johnson RL, Martin JF.
|
| Nature 401(6750):276-8 1999
|
| 69 | LEFTY2, PITX2
|
| The novel Cer-like protein Caronte mediates the establishment of embryonic left-right asymmetry.
|
| Rodriguez Esteban C, Capdevila J, Economides AN, Pascual J, Ortiz A, Izpisua Belmonte JC.
|
| Nature 401(6750):243-51. 1999
|
| 70 | PITX2
|
| Expression of the members of the Ptx family of transcription factors in human pituitary adenomas.
|
| Pellegrini-Bouiller I, Manrique C, Gunz G, Grino M, Zamora AJ, Figarella-Branger D, Grisoli F, Jaquet P, Enjalbert A.
|
| J Clin Endocrinol Metab. 84(6):2212-20. 1999
|
| 71 | IHG2, PITX2
|
| Autosomal dominant iris hypoplasia is caused by a mutation in the Rieger syndrome (RIEG/PITX2) gene.
|
| Alward WL, Semina EV, Kalenak JW, Heon E, Sheth BP, Stone EM, Murray JC.
|
| Am J Ophthalmol 125(1):98-100. 1998
|
| 72 | PITX2, RIEG1
|
| Construction and analysis of a sequence-ready map in 4q25 : Rieger syndrome can be caused by haploinsufficiency of RIEG, but also by chromosome breaks 90 kb upstream of this gene.
|
| Flomen RH, Vatcheva R, Gorman PA, Baptista PR, Groet J, Barisic I, Ligutic I, Nizetic D.
|
| Genomics 47(3):409-13. 1998
|
| 73 | IHG2, PITX2
|
| Mutation in the RIEG1 gene in patients with iridogoniodysgenesis syndrome.
|
| Kulak SC, Kozlowski K, Semina EV, Pearce WG, Walter MA.
|
| Hum Mol Genet 7(7):1113-7. 1998
|
| 74 | PITX2
|
| Pitx2 participates in the late phase of the pathway controlling left-right asymmetry.
|
| Piedra ME, Icardo JM, Albajar M, Rodriguez-Rey JC, Ros MA.
|
| Cell 94(3):319-24. 1998
|
| 75 | PITX2
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