| 1 | PIK3CG
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| Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs).
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| Vadas O, Dbouk HA, Shymanets A, Perisic O, Burke JE, Abi Saab WF, Khalil BD, Harteneck C, Bresnick AR, Nürnberg B, Backer JM, Williams RL.
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| Proc Natl Acad Sci U S A 110(47):18862-7. doi: 10.1073/pnas.1304801110. Epub 2013 Nov 4.
2013
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| 2 | PIK3CG, RAP1A
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| PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth.
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| Schmid MC, Franco I, Kang SW, Hirsch E, Quilliam LA, Varner JA.
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| PLoS One 8(4):e60226. doi: 10.1371/journal.pone.0060226. Epub 2013 Apr 2.
2013
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| 3 | PIK3CG
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| Phosphoinositide 3-kinase gamma in T cell biology and disease therapy.
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| Fung-Leung WP.
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| Ann N Y Acad Sci 1280:40-3. doi: 10.1111/nyas.12029.
2013
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| 4 | PIK3CG
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| Phosphoinositide 3-kinase γ inhibits cardiac GSK-3 independently of Akt.
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| Mohan ML, Jha BK, Gupta MK, Vasudevan NT, Martelli EE, Mosinski JD, Naga Prasad SV.
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| Sci Signal 6(259):ra4. doi: 10.1126/scisignal.2003308.
2013
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| 5 | PIK3C2B, PIK3CG
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| Class II phosphoinositide 3-kinases contribute to endothelial cells morphogenesis.
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| Tibolla G, Piñeiro R, Chiozzotto D, Mavrommati I, Wheeler AP, Norata GD, Catapano AL, Maffucci T, Falasca M.
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| PLoS One 8(1):e53808. doi: 10.1371/journal.pone.0053808. Epub 2013 Jan 8.
2013
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| 6 | PIK3CG, RALA
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| Elevated RalA activity in the hippocampus of PI3Kγ knock-out mice lacking NMDAR-dependent long-term depression.
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| Sim SE, Lee HR, Kim JI, Choi SL, Bakes J, Jang DJ, Lee K, Han K, Kim E, Kaang BK.
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| BMB Rep 46(2):103-6.
2013
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| 7 | PIK3CG, PIK3R5, PIK3R6
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| Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis.
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| Brazzatti JA, Klingler-Hoffmann M, Haylock-Jacobs S, Harata-Lee Y, Niu M, Higgins MD, Kochetkova M, Hoffmann P, McColl SR.
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| Oncogene 31(18):2350-61. doi: 10.1038/onc.2011.414. Epub 2011 Sep 26.
2012
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| 8 | CCL2, PIK3CG
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| Key role of PI3Kγ in monocyte chemotactic protein-1-mediated amplification of PDGF-induced aortic smooth muscle cell migration.
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| Fougerat A, Smirnova NF, Gayral S, Malet N, Hirsch E, Wymann MP, Perret B, Martinez LO, Douillon M, Laffargue M.
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| Br J Pharmacol 166(5):1643-53. doi: 10.1111/j.1476-5381.2012.01866.x.
2012
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| 9 | PIK3CA, PIK3CB, PIK3CG
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| Isoform-specific phosphoinositide 3-kinase inhibitors exert distinct effects in solid tumors.
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| Edgar KA, Wallin JJ, Berry M, Lee LB, Prior WW, Sampath D, Friedman LS, Belvin M.
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| Cancer Res 70(3):1164-72. Epub 2010 Jan 26.PMID: 20103642 2010
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| 10 | PIK3CG
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| PI3Kgamma regulates cartilage damage in chronic inflammatory arthritis.
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| Hayer S, Pundt N, Peters MA, Wunrau C, Kühnel I, Neugebauer K, Strietholt S, Zwerina J, Korb A, Penninger J, Joosten LA, Gay S, Rückle T, Schett G, Pap T.
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| FASEB J 23(12):4288-98. Epub 2009 Sep 4.PMID: 19734303 2009
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| 11 | PIK3CG
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| PI3Kgamma activation by CXCL12 regulates tumor cell adhesion and invasion.
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| Monterrubio M, Mellado M, Carrera AC, Rodríguez-Frade JM.
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| Biochem Biophys Res Commun 388(2):199-204. Epub 2009 Aug 4.PMID: 19660434 2009
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| 12 | PIK3CG
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| PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis.
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| Ferguson GJ, Milne L, Kulkarni S, Sasaki T, Walker S, Andrews S, Crabbe T, Finan P, Jones G, Jackson S, Camps M, Rommel C, Wymann M, Hirsch E, Hawkins P, Stephens L.
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| Nat Cell Biol 9(1):86-91. Epub 2006 Dec 17. 2007
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| 13 | PIK3CG, PIK3R5, PIK3R6
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| Characterization of p87PIKAP, a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B.
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| Voigt P, Dorner MB, Schaefer M.
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| J Biol Chem 281(15):9977-86. Epub 2006 Feb 13.
2006
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| 14 | PIK3CG, PIK3R5, PIK3R6
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| p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma.
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| Suire S, Coadwell J, Ferguson GJ, Davidson K, Hawkins P, Stephens L.
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| Curr Biol 15(6):566-70.
2005
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| 15 | PIK3CG, PIK3R5, PIK3R6
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| Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase gamma.
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| Voigt P, Brock C, Nürnberg B, Schaefer M.
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| J Biol Chem 280(6):5121-7. Epub 2004 Dec 20.
2005
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| 16 | PIK3CG, PDE3B
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| PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects.
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| Patrucco E, Notte A, Barberis L, Selvetella G, Maffei A, Brancaccio M, Marengo S, Russo G, Azzolino O, Rybalkin SD, Silengo L, Altruda F, Wetzker R, Wymann MP, Lembo G, Hirsch E.
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| Cell 118(3):375-87. 2004
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| 17 | PIK3CG
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| Overgrowth syndromes: is dysfunctional PI3-kinase signalling a unifying mechanism?
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| Barker KT, Houlston RS.
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| Eur J Hum Genet 11(9):665-70. 2003
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| 18 | PIK3CG, PIK3R5
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| Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma.
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| Brock C, Schaefer M, Reusch HP, Czupalla C, Michalke M, Spicher K, Schultz G, Nürnberg B.
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| J Cell Biol 160(1):89-99. Epub 2002 Dec 30.
2003
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| 19 | PIK3CG
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| Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways.
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| Crackower MA, Oudit GY, Kozieradzki I, Sarao R, Sun H, Sasaki T, Hirsch E, Suzuki A, Shioi T, Irie-Sasaki J, Sah R, Cheng HY, Rybin VO, Lembo G, Fratta L, Oliveira-dos-Santos AJ, Benovic JL, Kahn CR, Izumo S, Steinberg SF, Wymann MP, Backx PH, Penninger JM.
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| Cell 110(6):737-49. 2002
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| 20 | PIK3CG
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| Genomic structure of the PIK3CG gene on chromosome band 7q22 and evaluation as a candidate myeloid tumor suppressor.
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| Kratz CP, Emerling BM, Bonifas J, Wang W, Green ED, Beau MM, Shannon KM.
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| Blood 99(1):372-4. 2002
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| 21 | PIK3CG
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| Human platelets contain p110delta phosphoinositide 3-kinase.
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| Zhang J, Vanhaesebroeck B, Rittenhouse SE.
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| Biochem Biophys Res Commun 296(1):178-81. 2002
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| 22 | PIK3CG
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| Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase.
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| Stoyanov B, Volinia S, Hanck T, Rubio I, Loubtchenkov M, Malek D, Stoyanova S, Vanhaesebroeck B, Dhand R, Nurnberg B, et al.
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| Science 269(5224):690-3. 1995
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