| 1 | CRKL, PIK3CB
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| CRKL Mediates p110β-Dependent PI3K Signaling in PTEN-Deficient Cancer Cells.
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| Zhang J, Gao X, Schmit F, Adelmant G, Eck MJ, Marto JA, Zhao JJ, Roberts TM.
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| Cell Rep 20(3):549-557. doi: 10.1016/j.celrep.2017.06.054.
2017
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| 2 | PIK3CA, PIK3CB, PIK3CG
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| Isoform-specific phosphoinositide 3-kinase inhibitors exert distinct effects in solid tumors.
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| Edgar KA, Wallin JJ, Berry M, Lee LB, Prior WW, Sampath D, Friedman LS, Belvin M.
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| Cancer Res 70(3):1164-72. Epub 2010 Jan 26.PMID: 20103642 2010
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| 3 | PIK3CA, PIK3CB
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| Loss of cardiac phosphoinositide 3-kinase p110 alpha results in contractile dysfunction.
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| Lu Z, Jiang YP, Wang W, Xu XH, Mathias RT, Entcheva E, Ballou LM, Cohen IS, Lin RZ.
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| Circulation 120(4):318-25. Epub 2009 Jul 13.PMID: 19597047 2009
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| 4 | PIK3CB
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| Role of phosphoinositide 3-kinase beta in glycoprotein VI-mediated Akt activation in platelets.
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| Kim S, Mangin P, Dangelmaier C, Lillian R, Jackson SP, Daniel JL, Kunapuli SP.
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| J Biol Chem 284(49):33763-72. Epub 2009 Aug 21.PMID: 19700402 2009
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| 5 | PIK3CB
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| PI3K p110beta positively regulates lipopolysaccharide-induced IL-12 production in human macrophages and dendritic cells and JNK1 plays a novel role.
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| Utsugi M, Dobashi K, Ono A, Ishizuka T, Matsuzaki S, Hisada T, Shimizu Y, Kawata T, Aoki H, Kamide Y, Mori M.
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| J Immunol 182(9):5225-31.PMID: 19380768 2009
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| 6 | PIK3CA, PIK3CB
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| Phosphoinositide 3-kinases p110alpha and p110beta regulate cell cycle entry, exhibiting distinct activation kinetics in G1 phase.
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| Marqués M, Kumar A, Cortés I, Gonzalez-García A, Hernández C, Moreno-Ortiz MC, Carrera AC.
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| Mol Cell Biol 28(8):2803-14. Epub 2008 Feb 19.PMID: 18285463 2008
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| 7 | PIK3CB, PIK3R1
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| Phosphoinositide 3-OH kinase p85alpha and p110beta are essential for androgen receptor transactivation and tumor progression in prostate cancers.
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| Zhu Q, Youn H, Tang J, Tawfik O, Dennis K, Terranova PF, Du J, Raynal P, Thrasher JB, Li B.
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| Oncogene 27(33):4569-79. Epub 2008 Mar 31.
2008
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| 8 | PIK3CA, PIK3CB
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| Mutation analysis of PIK3CA and PIK3CB in esophageal cancer and Barrett's esophagus.
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| Phillips WA, Russell SE, Ciavarella ML, Choong DY, Montgomery KG, Smith K, Pearson RB, Thomas RJ, Campbell IG.
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| Int J Cancer 118(10):2644-6.PMID: 16380997 2006
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| 9 | PIK3CB
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| PI 3-kinase p110beta: a new target for antithrombotic therapy.
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| Jackson SP, Schoenwaelder SM, Goncalves I, Nesbitt WS, Yap CL, Wright CE, Kenche V, Anderson KE, Dopheide SM, Yuan Y, Sturgeon SA, Prabaharan H, Thompson PE, Smith GD, Shepherd PR, Daniele N, Kulkarni S, Abbott B, Saylik D, Jones C, Lu L, Giuliano S, Hughan SC, Angus JA, Robertson AD, Salem HH.
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| Nat Med 11(6):507-14. Epub 2005 Apr 17. 2005
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| 10 | PIK3CB
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| A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid
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| Yart A, Roche S, Wetzker R, Laffargue M, Tonks N, Mayeux P, Chap H, Raynal P.
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| J Biol Chem 277(24):21167-78. 2002
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| 11 | PIK3CB
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| Gene encoding the catalytic subunit p110beta of human phosphatidylinositol 3-kinase: cloning, genomic structure, and screening for variants in patients with type 2 diabetes.
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| Kossila M, Sinkovic M, Karkkainen P, Laukkanen MO, Miettinen R, Rissanen J, Kekalainen P, Kuusisto J, Yla-Herttuala S, Laakso M.
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| Diabetes 49(10):1740-3. 2000
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| 12 | PIK3CB
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| Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85.
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| Hu P, Mondino A, Skolnik EY, Schlessinger J.
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| Mol Cell Biol 13(12):7677-88.PMID: 8246984 1993
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