1 | KNTC1, PIAS4, ZW10
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| Rod/Zw10 complex is required for PIASy-dependent centromeric SUMOylation.
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| Ryu H, Azuma Y.
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| J Biol Chem 285(42):32576-85. doi: 10.1074/jbc.M110.153817. Epub 2010 Aug 9.
2010
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2 | PIAS1, PIAS4, SUMO1, SUMO2, SUMO3
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| Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks.
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| Galanty Y, Belotserkovskaya R, Coates J, Polo S, Miller KM, Jackson SP.
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| Nature 462(7275):935-9. 2009
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3 | PIAS4, SMAD3
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| Sumoylation of Smad3 stimulates its nuclear export during PIASy-mediated suppression of TGF-beta signaling.
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| Imoto S, Ohbayashi N, Ikeda O, Kamitani S, Muromoto R, Sekine Y, Matsuda T.
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| Biochem Biophys Res Commun 370(2):359-65. Epub 2008 Mar 31.
2008
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4 | PIAS4, RB1CC1
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| Spatial interplay between PIASy and FIP200 in the regulation of signal transduction and transcriptional activity.
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| Martin N, Schwamborn K, Urlaub H, Gan B, Guan JL, Dejean A.
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| Mol Cell Biol 28(8):2771-81. Epub 2008 Feb 19.
2008
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5 | ETV4, PIAS4
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| Repression of E1AF transcriptional activity by sumoylation and PIASy.
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| Nishida T, Terashima M, Fukami K, Yamada Y.
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| Biochem Biophys Res Commun 360(1):226-32. Epub 2007 Jun 14.
2007
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6 | ETS1, PIAS4
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| PIASy controls ubiquitination-dependent proteasomal degradation of Ets-1.
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| Nishida T, Terashima M, Fukami K, Yamada Y.
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| Biochem J 405(3):481-8.
2007
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7 | PIAS4
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| The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis.
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| Bischof O, Schwamborn K, Martin N, Werner A, Sustmann C, Grosschedl R, Dejean A.
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| Mol Cell 22(6):783-94.
2006
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8 | PIAS4
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| The RING domain of PIASy is involved in the suppression of bone morphogenetic protein-signaling pathway.
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| Imoto S, Sugiyama K, Yamamoto T, Matsuda T.
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| Biochem Biophys Res Commun 319(1):275-82. 2004
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9 | PIAS4
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| Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3.
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| Imoto S, Sugiyama K, Muromoto R, Sato N, Yamamoto T, Matsuda T.
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| J Biol Chem 278(36):34253-8. Epub 2003 Jun 18. 2003
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10 | PIAS4
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| Modification of GATA-2 transcriptional activity in endothelial cells by the SUMO E3 ligase PIASy.
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| Chun TH, Itoh H, Subramanian L, Iniguez-Lluhi JA, Nakao K.
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| Circ Res 92(11):1201-8. Epub 2003 May 15. 2003
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11 | PIAS4
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| A transcriptional corepressor of Stat1 with an essential LXXLL signature motif.
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| Liu B, Gross M, ten Hoeve J, Shuai K.
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| Proc Natl Acad Sci U S A 98(6):3203-7. 2001
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12 | LEF1, PIAS4
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| PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies.
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| Sachdev S, Bruhn L, Sieber H, Pichler A, Melchior F, Grosschedl R.
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| Genes Dev 15(23):3088-103.
2001
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13 | PIAS1, PIAS4
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| Inhibition of Stat1-mediated gene activation by PIAS1.
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| Liu B, Liao J, Rao X, Kushner SA, Chung CD, Chang DD, Shuai K.
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| Proc Natl Acad Sci U S A 95(18):10626-31. 1998
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