| 1 | PI3
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| Anti-inflammatory Elafin in human fetal membranes.
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| Stalberg C, Noda N, Polettini J, Jacobsson B, Menon R.
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| J Perinat Med 45(2):237-244. doi: 10.1515/jpm-2016-0139.
2017
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| 2 | KLK5, KLK7, PI3, SPINK5
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| Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models.
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| McGovern JA, Meinert C, de Veer SJ, Hollier BG, Parker TJ, Upton Z.
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| Br J Dermatol 176(1):145-158. doi: 10.1111/bjd.14879. Epub 2016 Dec 22.
2017
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| 3 | PI3
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| Protective effects of elafin against adult asthma.
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| Tsai YS, Tseng YT, Chen PS, Lin MC, Wu CC, Huang MS, Wang CC, Chen KS, Lin YC, Wang TN.
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| Allergy Asthma Proc 37(2):15-24. doi: 10.2500/aap.2016.37.3932.
2016
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| 4 | ELANE, PI3
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| The serine protease inhibitor elafin maintains normal growth control by opposing the mitogenic effects of neutrophil elastase.
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| Caruso JA, Akli S, Pageon L, Hunt KK, Keyomarsi K.
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| Oncogene 34(27):3556-67. doi: 10.1038/onc.2014.284. Epub 2014 Sep 8. 2015
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| 5 | PI3
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| Elafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors.
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| Labidi-Galy SI, Clauss A, Ng V, Duraisamy S, Elias KM, Piao HY, Bilal E, Davidowitz RA, Lu Y, Badalian-Very G, Györffy B, Kang UB, Ficarro S, Ganesan S, Mills GB, Marto JA, Drapkin R.
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| Oncogene 34(3):373-83. doi: 10.1038/onc.2013.562. Epub 2014 Jan 27.
2015
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| 6 | PI3
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| Elafin expression in mucosa of fallopian tubes is altered by hydrosalpinx.
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| Neto EP, Fuhrich DG, Carson DD, Engel BJ, Savaris RF.
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| Reprod Sci 21(3):401-7. doi: 10.1177/1933719113497291. Epub 2013 Jul 24.
2014
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| 7 | PI3
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| Functional characterization of polymorphisms in the peptidase inhibitor 3 (elafin) gene and validation of their contribution to risk of acute respiratory distress syndrome.
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| Tejera P, O'Mahony DS, Owen CA, Wei Y, Wang Z, Gupta K, Su L, Villar J, Wurfel M, Christiani DC.
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| Am J Respir Cell Mol Biol 51(2):262-72. doi: 10.1165/rcmb.2013-0238OC.
2014
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| 8 | PI3
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| Elafin, an inhibitor of elastase, is a prognostic indicator in breast cancer.
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| Hunt KK, Wingate H, Yokota T, Liu Y, Mills GB, Zhang F, Fang B, Su CH, Zhang M, Yi M, Keyomarsi K.
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| Breast Cancer Res 15(1):R3. doi: 10.1186/bcr3374.
2013
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| 9 | PI3
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| The WAP protein Trappin-2/Elafin: a handyman in the regulation of inflammatory and immune responses.
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| Verrier T, Solhonne B, Sallenave JM, Garcia-Verdugo I.
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| Int J Biochem Cell Biol 44(8):1377-80. doi: 10.1016/j.biocel.2012.05.007. Epub 2012 May 23. Review.
2012
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| 10 | FOXA2, PI3
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| Epigenetic regulation of the transcription factor Foxa2 directs differential elafin expression in melanocytes and melanoma cells.
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| Yu KS, Jo JY, Kim SJ, Lee Y, Bae JH, Chung YH, Koh SS.
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| Biochem Biophys Res Commun 408(1):160-6. doi: 10.1016/j.bbrc.2011.04.001. Epub 2011 Apr 3.
2011
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| 11 | PI3
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| Elafin is a biomarker of graft-versus-host disease of the skin.
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| Paczesny S, Braun TM, Levine JE, Hogan J, Crawford J, Coffing B, Olsen S, Choi SW, Wang H, Faca V, Pitteri S, Zhang Q, Chin A, Kitko C, Mineishi S, Yanik G, Peres E, Hanauer D, Wang Y, Reddy P, Hanash S, Ferrara JL.
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| Sci Transl Med 2(13):13ra2. doi: 10.1126/scitranslmed.3000406.
2010
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| 12 | PI3
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| Elafin (SKALP/Trappin-2/proteinase inhibitor-3) is produced by the cervix in pregnancy and cervicovaginal levels are diminished in bacterial vaginosis.
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| Stock SJ, Duthie L, Tremaine T, Calder AA, Kelly RW, Riley SC.
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| Reprod Sci 16(12):1125-34. doi: 10.1177/1933719109341998. Epub 2009 Sep 1.
2009
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| 13 | PI3
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| Cross-linking of elafin/SKALP to elastic fibers in photodamaged skin: too much of a good thing?
|
| Schalkwijk J.
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| J Invest Dermatol 127(6):1286-7. Review.
2007
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| 14 | PI3
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| Elafin in human endometrium: an antiprotease and antimicrobial molecule expressed during menstruation.
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| King AE, Critchley HO, Sallenave JM, Kelly RW.
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| J Clin Endocrinol Metab 88(9):4426-31. 2003
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| 15 | CD74, DEFA5, DEFA6, ESD, CXCL1, IGHG3, IGLL2, LCN2, REG3A, PI3, REG1A, S100A9, S100P
|
| Ulcerative colitis and Crohn's disease : distinctive gene expression profiles and novel susceptibility candidate genes.
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| Lawrance IC, Fiocchi C, Chakravarti S.
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| Hum Mol Genet 10(5):445-56. 2001
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| 16 | PI3
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| Development and application of monoclonal antibodies against SKALP/elafin and other trappin family members.
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| Vandermeeren M, Daneels G, Bergers M, van Vlijmen-Willems I, Pol A, Geysen J, Schalkwijk J.
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| Arch Dermatol Res 293(7):343-9. 2001
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| 17 | PI3
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| TNF-alpha and serum induce SKALP/elafin gene expression in human keratinocytes by a p38 MAP kinase-dependent pathway.
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| Pfundt R, Wingens M, Bergers M, Zweers M, Frenken M, Schalkwijk J.
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| Arch Dermatol Res 292(4):180-7. 2000
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| 18 | PI3
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| Elafin is induced in epidermis in skin disorders with dermal neutrophilic infiltration: interleukin-1 beta and tumour necrosis factor-alpha stimulate its secretion in vitro.
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| Tanaka N, Fujioka A, Tajima S, Ishibashi A, Hirose S.
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| Br J Dermatol 143(4):728-32. 2000
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| 19 | PI3
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| The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core.
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| Schalkwijk J, et al.
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| Biochem J 340 ( Pt 3):569-77. Review. 1999
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| 20 | PI3
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| Human neutrophil elastase regulates the expression and secretion of elafin (elastase-specific inhibitor) in type II alveolar epithelial cells.
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| Reid PT, Marsden ME, Cunningham GA, Haslett C, Sallenave JM.
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| FEBS Lett 457(1):33-7 1999
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| 21 | PI3
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| SKALP/elafin gene polymorphisms are not associated with pustular forms of psoriasis.
|
| Kuijpers ALA, et al.
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| Clin Genet 54 : 96-101. 1998
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| 22 | PI3
|
| Assignment of the human gene encoding the epidermal serine proteinase inhibitor SKALP (P13) to chromosome region 20q12-q13.
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| Molhuizen HOF, et al.
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| Cytogenet Cell Genet 66 : 129-131. 1994
|