Citations for
1PGF
Identification of PGF as a New Gene for Neovascular Age-Related Macular Degeneration in a Chinese Population.
Chen LJ, Ma L, Chu WK, Lai TY, Chen H, Brelén ME, Rong SS, Young AL, Tam PO, Zhang M, Pang CP.
Invest Ophthalmol Vis Sci 57(4):1714-20. doi: 10.1167/iovs.IOVS-15-18677. 2016
2MAPK14, MMP9, PGF
Placental growth factor promotes metastases of non-small cell lung cancer through MMP9.
Zhang W, Zhang T, Lou Y, Yan B, Cui S, Jiang L, Han B.
Cell Physiol Biochem 37(3):1210-8. doi: 10.1159/000430244. Epub 2015 Sep 30. 2015
3PGF
Correlation between cell-free mRNA expressions and PLGF protein level in severe preeclampsia.
Pramatirta AY, Mose J, Effendi JS, Krisnadi SR, Anwar AD, Fauziah PN, Gurnadi JI, Rihibiha DD.
BMC Res Notes 8:208. doi: 10.1186/s13104-015-1186-9. 2015
4FLT1, PGF
Difference of concentration of placental soluble fms-like tyrosine kinase-1(sFlt-1), placental growth factor (PlGF), and sFlt-1/PlGF ratio in severe preeclampsia and normal pregnancy.
Gurnadi JI, Mose J, Handono B, Satari MH, Anwar AD, Fauziah PN, Yogi Pramatirta A, Rihibiha DD.
BMC Res Notes 8:534. doi: 10.1186/s13104-015-1506-0. 2015
5PGF
Placenta growth factor promotes migration through regulating epithelial-mesenchymal transition-related protein expression in cervical cancer.
Huang W, Zhu S, Liu Q, Li C, Li L.
Int J Clin Exp Pathol 7(12):8506-19. eCollection 2014. 2014
6PGF
PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema.
Hou HH, Cheng SL, Chung KP, Wei SC, Tsao PN, Lu HH, Wang HC, Yu CJ.
Respir Res 15:106. doi: 10.1186/s12931-014-0106-1. 2014
7PGF
A role of placental growth factor in hair growth.
Yoon SY, Yoon JS, Jo SJ, Shin CY, Shin JY, Kim JI, Kwon O, Kim KH.
J Dermatol Sci 74(2):125-34. doi: 10.1016/j.jdermsci.2014.01.011. Epub 2014 Feb 6. 2014
8PGF
Placenta growth factor and vascular endothelial growth factor a have differential, cell-type specific patterns of expression in vascular cells.
Xiang L, Varshney R, Rashdan NA, Shaw JH, Lloyd PG.
Microcirculation 21(5):368-79. doi: 10.1111/micc.12113. 2014
9KLF1, PGF
Heme-bound iron activates placenta growth factor in erythroid cells via erythroid Krüppel-like factor.
Wang X, Mendelsohn L, Rogers H, Leitman S, Raghavachari N, Yang Y, Yau YY, Tallack M, Perkins A, Taylor JG 6th, Noguchi CT, Kato GJ.
Blood 124(6):946-54. doi: 10.1182/blood-2013-11-539718. Epub 2014 Jun 10. 2014
10FLT1, PGF
Targeting VEGFR1 on endothelial progenitors modulates their differentiation potential.
d'Audigier C, Gautier B, Yon A, Alili JM, Guérin CL, Evrard SM, Godier A, Haviari S, Reille-Serroussi M, Huguenot F, Dizier B, Inguimbert N, Borgel D, Bièche I, Boisson-Vidal C, Roncal C, Carmeliet P, Vidal M, Gaussem P, Smadja DM.
Angiogenesis 17(3):603-16. doi: 10.1007/s10456-013-9413-2. Epub 2014 Jan 14. 2014
11ADGRG2, MMP13, PGF
G-Protein coupled receptor 64 promotes invasiveness and metastasis in Ewing sarcomas through PGF and MMP1.
Richter GH, Fasan A, Hauer K, Grunewald TG, Berns C, Rössler S, Naumann I, Staege MS, Fulda S, Esposito I, Burdach S.
J Pathol 230(1):70-81. doi: 10.1002/path.4170. Epub 2013 Mar 14. 2013
12PGF
Placental growth factor and soluble fms-like tyrosine kinase-1 are useful markers for the prediction of preeclampsia but not for small for gestational age neonates: a longitudinal study.
Rizos D, Eleftheriades M, Karampas G, Rizou M, Haliassos A, Hassiakos D, Vitoratos N.
Eur J Obstet Gynecol Reprod Biol 171(2):225-30. doi: 10.1016/j.ejogrb.2013.08.040. Epub 2013 Sep 4. 2013
13HIF1A, PGF, VEGFA
VEGF, PIGF and HIF-1α in placentas of early- and late-onset pre-eclamptic patients.
Sezer SD, Küçük M, Döger FK, Yüksel H, Odabaşi AR, Türkmen MK, Cakmak BÇ, Ömürlü IK, Kinaş MG.
Gynecol Endocrinol 29(8):797-800. doi: 10.3109/09513590.2013.801437. Epub 2013 Jun 14. 2013
14PGF
The course of angiogenic factors in early- vs. late-onset preeclampsia and HELLP syndrome.
Schaarschmidt W, Rana S, Stepan H.
J Perinat Med 41(5):511-6. doi: 10.1515/jpm-2012-0248. 2013
15FLT1, PGF
Presymptomatic prediction of preeclampsia with angiogenic factors, in high risk pregnant women.
Teixeira PG, Reis ZS, Andrade SP, Rezende CA, Lage EM, Velloso EP, Santana CA, Cabral AC.
Hypertens Pregnancy 32(3):312-20. doi: 10.3109/10641955.2013.807818. 2013
16PGF
Proteolytic processing regulates placental growth factor activities.
Hoffmann DC, Willenborg S, Koch M, Zwolanek D, Müller S, Becker AK, Metzger S, Ehrbar M, Kurschat P, Hellmich M, Hubbell JA, Eming SA.
J Biol Chem 288(25):17976-89. doi: 10.1074/jbc.M113.451831. Epub 2013 May 3. 2013
17PGF
Post-transcriptional regulation of placenta growth factor mRNA by hydrogen peroxide.
Shaw JH, Lloyd PG.
Microvasc Res 84(2):155-60. doi: 10.1016/j.mvr.2012.05.009. Epub 2012 Jun 5. 2012
18PGF
Increased expression of placental growth factor in patients with temporal lobe epilepsy and a rat model.
Xu Y, Luo J, Yue Z, Wu L, Zhang X, Zhou C, Zhao F, Wang X, Chen G.
Brain Res 1429:124-33. doi: 10.1016/j.brainres.2011.10.008. Epub 2011 Oct 6. 2012
19PGF, VEGFA
An unexpected tail of VEGF and PlGF in pre-eclampsia.
Bates DO.
Biochem Soc Trans 39(6):1576-82. doi: 10.1042/BST20110671. Review. 2011
20PGF
Placental growth factor regulates cardiac adaptation and hypertrophy through a paracrine mechanism.
Accornero F, van Berlo JH, Benard MJ, Lorenz JN, Carmeliet P, Molkentin JD.
Circ Res 109(3):272-80. doi: 10.1161/CIRCRESAHA.111.240820. Epub 2011 Jun 2. 2011
21PGF
Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease.
Van de Veire S, Stalmans I, Heindryckx F, Oura H, Tijeras-Raballand A, Schmidt T, Loges S, Albrecht I, Jonckx B, Vinckier S, Van Steenkiste C, Tugues S, Rolny C, De Mol M, Dettori D, Hainaud P, Coenegrachts L, Contreres JO, Van Bergen T, Cuervo H, Xiao WH, Le Henaff C, Buysschaert I, Kharabi Masouleh B, Geerts A, Schomber T, Bonnin P, Lambert V, Haustraete J, Zacchigna S, Rakic JM, Jiménez W, Noël A, Giacca M, Colle I, Foidart JM, Tobelem G, Morales-Ruiz M, Vilar J, Maxwell P, Vinores SA, Carmeliet G, Dewerchin M, Claesson-Welsh L, Dupuy E, Van Vlierberghe H, Christofori G, Mazzone M, Detmar M, Collen D, Carmeliet P.
Cell 141(1):178-90. 2010
22PGF
PlGF blockade does not inhibit angiogenesis during primary tumor growth.
Bais C, Wu X, Yao J, Yang S, Crawford Y, McCutcheon K, Tan C, Kolumam G, Vernes JM, Eastham-Anderson J, Haughney P, Kowanetz M, Hagenbeek T, Kasman I, Reslan HB, Ross J, Van Bruggen N, Carano RA, Meng YJ, Hongo JA, Stephan JP, Shibuya M, Ferrara N.
Cell 141(1):166-77. 2010
23PGF
PGF isoforms, PLGF-1 and PGF-2 and the PGF receptor, neuropilin, in human breast cancer: prognostic significance.
Escudero-Esparza A, Martin TA, Douglas-Jones A, Mansel RE, Jiang WG.
Oncol Rep 23(2):537-44.PMID: 20043119 2010
24ENG, FLT1, PGF
Circulating angiogenic and antiangiogenic factors in women with eclampsia.
Vaisbuch E, Whitty JE, Hassan SS, Romero R, Kusanovic JP, Cotton DB, Sorokin Y, Karumanchi SA.
Am J Obstet Gynecol m J Obstet Gynecol. 2010 Nov 8. [Epub ahead of print]PMID: 21062661 2010
25EGR1, PGF
Placenta growth factor-induced early growth response 1 (Egr-1) regulates hypoxia-inducible factor-1alpha (HIF-1alpha) in endothelial cells.
Patel N, Kalra VK.
J Biol Chem 285(27):20570-9. Epub 2010 May 6. 2010
26PGF
Placenta growth factor is a survival factor for human malignant mesothelioma cells.
Albonici L, Doldo E, Palumbo C, Orlandi A, Bei R, Pompeo E, Mineo TC, Modesti A, Manzari V.
Int J Immunopathol Pharmacol 22(2):389-401. 2009
27FLT1, PGF
Role of placenta growth factor and its receptor flt-1 in rheumatoid inflammation: a link between angiogenesis and inflammation.
Yoo SA, Yoon HJ, Kim HS, Chae CB, De Falco S, Cho CS, Kim WU.
Arthritis Rheum 60(2):345-54. 2009
28MTF1, PGF
Metal transcription factor-1 is involved in hypoxia-dependent regulation of placenta growth factor in trophoblast-derived cells.
Nishimoto F, Sakata M, Minekawa R, Okamoto Y, Miyake A, Isobe A, Yamamoto T, Takeda T, Ishida E, Sawada K, Morishige K, Kimura T.
Endocrinology 150(4):1801-8. Epub 2008 Nov 20. 2009
29HIF1A, PGF
Placenta growth factor induces 5-lipoxygenase-activating protein to increase leukotriene formation in sickle cell disease.
Patel N, Gonsalves CS, Yang M, Malik P, Kalra VK.
Blood 113(5):1129-38. Epub 2008 Oct 22. 2009
30PGF
Endostatin, placental growth factor, and fibroblast growth factors-1 and -2 in the sera of patients with primary osteosarcomas.
Babkina IV, Osipov DA, Solovyov YN, Bulycheva IV, Machak GN, Aliev MD, Kushlinsky NE.
Bull Exp Biol Med 148(2):246-9. 2009
31PGF
PlGF expression in pre-invasive and invasive lesions of uterine cervix is associated with angiogenesis and lymphangiogenesis.
Yang S, Cheng H, Cai J, Cai L, Zhang J, Wang Z.
APMIS 117(11):831-8. 2009
32PGF
Treatment with recombinant placental growth factor (PlGF) enhances both angiogenesis and arteriogenesis and improves survival after myocardial infarction.
Takeda Y, Uemura S, Iwama H, Imagawa K, Nishida T, Onoue K, Takemoto Y, Soeda T, Okayama S, Somekawa S, Ishigami K, Takaoka M, Kawata H, Kubo A, Horii M, Nakajima T, Saito Y.
Circ J 73(9):1674-82. Epub 2009 Jul 15. 2009
33MMP9, PGF
PlGF-MMP-9-expressing cells restore microcirculation and efficacy of cell therapy in aged dystrophic muscle.
Gargioli C, Coletta M, De Grandis F, Cannata SM, Cossu G.
Nat Med 14(9):973-8. Epub 2008 Jul 27. 2008
34GCM1, PGF
Glial cell missing 1 regulates placental growth factor (PGF) gene transcription in human trophoblast.
Chang M, Mukherjea D, Gobble RM, Groesch KA, Torry RJ, Torry DS.
Biol Reprod 78(5):841-51. Epub 2007 Dec 26. 2008
35PGF
Placental growth factor attenuates suppression of erythroid colony formation by interferon.
Dallalio G, Means RT Jr.
Transl Res 152(5):233-8. Epub 2008 Oct 29. 2008
36HIF1A, PGF
Placenta growth factor augments endothelin-1 and endothelin-B receptor expression via hypoxia-inducible factor-1 alpha.
Patel N, Gonsalves CS, Malik P, Kalra VK.
Blood 112(3):856-65. Epub 2008 Apr 14. 2008
37FIGF, FLT1, FLT4, KDR, NRP1, NRP2, PGF, VEGFA, VEGFB, VEGFC
Biology of vascular endothelial growth factors.
Roy H, Bhardwaj S, YlŠ-Herttuala S.
FEBS Lett 580(12):2879-87. Epub 2006 Apr 17. 2006
38PGF
Placental growth factor mediates mesenchymal cell development, cartilage turnover, and bone remodeling during fracture repair.
Maes C, Coenegrachts L, Stockmans I, Daci E, Luttun A, Petryk A, Gopalakrishnan R, Moermans K, Smets N, Verfaillie CM, Carmeliet P, Bouillon R, Carmeliet G.
J Clin Invest 116(5):1230-42. Epub 2006 Apr 13. 2006
39VEGFA, PGF
VEGF-A and PlGF-1 stimulate chemotactic migration of human mesenchymal progenitor cells.
Fiedler J, Leucht F, Waltenberger J, Dehio C, Brenner RE.
Biochem Biophys Res Commun 334(2):561-8. 2005
40FLT1, KDR, PGF, VEGFA
Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1.
Autiero M, Waltenberger J, Communi D, Kranz A, Moons L, Lambrechts D, Kroll J, Plaisance S, De Mol M, Bono F, Kliche S, Fellbrich G, Ballmer-Hofer K, Maglione D, Mayr-Beyrle U, Dewerchin M, Dombrowski S, Stanimirovic D, Van Hummelen P, Dehio C, Hicklin DJ, Persico G, Herbert JM, Communi D, Shibuya M, Collen D, Conway EM, Carmeliet P.
Nat Med 9(7):936-43. 2003
41PGF
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.
Carmeliet P, Moons L, Luttun A, Vincenti V, Compernolle V, De Mol M, Wu Y, Bono F, Devy L, Beck H, Scholz D, Acker T, DiPalma T, Dewerchin M, Noel A, Stalmans I, Barra A, Blacher S, Vandendriessche T, Ponten A, Eriksson U, Plate KH, Foidart JM, Schaper W, Charnock-Jones DS, Hicklin DJ, Herbert JM, Collen D, Persico MG.
Nat Med 7(5):575-83. 2001
42KLRD1, NKG2@, PGF, PZP
A sequence-ready physical map of the region containing the human natural killer gene complex on chromosome 12p12.3-p13.2.
Renedo M, Arce I, Montgomery K, Roda-Navarro P, Lee E, Kucherlapati R, Fernandez-Ruiz E.
Genomics 65(2):129-36. 2000
43PGF, NEUROD4, TGFB3
An expression map from human chromosome 14q24.3.
Sharma V, Poorkaj P, Hisama F, Bonnycastle L, Yu CE, Massa H, Trask B, Clancy KP, Patterson D, Weissman SM, Schellenberg GD.
Genomics 47(2):314-8. 1998
44PGF
Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-gamma and migration of endothelial cells expressing Flt 1.
Landgren E, Schiller P, Cao Y, Claesson-Welsh L.
Oncogene 16(3):359-67. 1998
45PGF
Placenta growth factor: identification and characterization of a novel isoform generated by RNA alternative splicing.
Cao Y, Ji WR, Qi P, Rosin A, Cao Y.
Biochem Biophys Res Commun 235(3):493-8. 1997
46PGF, VEGFA
Assignment of vascular endothelial growth factor (VEGF) and placenta growth factor (PIGF) genes to human chromosome 6p12-p21 and 14q24-q31 regions, respectively.
Mattei MG, et al.
Genomics 32 : 168-169. 1996
47PGF
Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PIGF), are transcribed from a single gene of chromosome 14.
Maglione D, et al.
Oncogene 8 : 925-931. 1993
48PGF
A heparin-binding form of placenta growth factor (PlGF-2) is expressed in human umbilical vein endothelial cells and in placenta.
Hauser S, Weich HA.
Growth Factors 9(4):259-68. 1993
49PGF
Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor.
Maglione D, Guerriero V, Viglietto G, Delli-Bovi P, Persico MG.
Proc Natl Acad Sci U S A 88(20):9267-71. 1991