| 1 | PF4
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| Regulatory role of Megakaryocytes on Hematopoietic Stem Cells Quiescence by CXCL4/PF4 in Bone Marrow Niche.
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| Norozi F, Shahrabi S, Mendelson A, Hajizamani S, Saki N.
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| Leuk Res euk Res. 2016 Jan 2. pii: S0145-2126(15)30569-5. doi: 10.1016/j.leukres.2015.12.012. [Epub ahead of print] Review.
2016
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| 2 | PF4
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| Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion.
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| Bruns I, Lucas D, Pinho S, Ahmed J, Lambert MP, Kunisaki Y, Scheiermann C, Schiff L, Poncz M, Bergman A, Frenette PS.
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| Nat Med 20(11):1315-20. doi: 10.1038/nm.3707. Epub 2014 Oct 19.
2014
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| 3 | PF4, RUNX1
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| RUNX1, but not its familial platelet disorder mutants, synergistically activates PF4 gene expression in combination with ETS family proteins.
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| Okada Y, Watanabe M, Nakai T, Kamikawa Y, Shimizu M, Fukuhara Y, Yonekura M, Matsuura E, Hoshika Y, Nagai R, Aird WC, Doi T.
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| J Thromb Haemost 11(9):1742-50. doi: 10.1111/jth.12355.
2013
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| 4 | PF4
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| Platelet factor 4 mediates vascular smooth muscle cell injury responses.
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| Shi G, Field DJ, Long X, Mickelsen D, Ko KA, Ture S, Korshunov VA, Miano JM, Morrell CN.
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| Blood 121(21):4417-27. doi: 10.1182/blood-2012-09-454710. Epub 2013 Apr 8.
2013
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| 5 | PF4
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| CXCL4-platelet factor 4, heparin-induced thrombocytopenia and cancer.
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| Sandset PM.
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| Thromb Res 129 Suppl 1:S97-100. doi: 10.1016/S0049-3848(12)70026-9. Review.
2012
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| 6 | ACKR1, PF4
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| Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparum.
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| McMorran BJ, Wieczorski L, Drysdale KE, Chan JA, Huang HM, Smith C, Mitiku C, Beeson JG, Burgio G, Foote SJ.
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| Science 338(6112):1348-51. doi: 10.1126/science.1228892.
2012
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| 7 | ELF1, ETS1, GABPA, PF4
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| Multiple ETS family proteins regulate PF4 gene expression by binding to the same ETS binding site.
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| Okada Y, Nobori H, Shimizu M, Watanabe M, Yonekura M, Nakai T, Kamikawa Y, Wakimura A, Funahashi N, Naruse H, Watanabe A, Yamasaki D, Fukada S, Yasui K, Matsumoto K, Sato T, Kitajima K, Nakano T, Aird WC, Doi T.
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| PLoS One 6(9):e24837. doi: 10.1371/journal.pone.0024837. Epub 2011 Sep 12.
2011
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| 8 | CPB2, PF4, THBD
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| Platelet factor 4 inhibits thrombomodulin-dependent activation of thrombin-activatable fibrinolysis inhibitor (TAFI) by thrombin.
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| Mosnier LO.
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| J Biol Chem 286(1):502-10. doi: 10.1074/jbc.M110.147959. Epub 2010 Nov 1.
2011
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| 9 | PF4
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| CXC chemokine ligand 4 (Cxcl4) is a platelet-derived mediator of experimental liver fibrosis.
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| Zaldivar MM, Pauels K, von Hundelshausen P, Berres ML, Schmitz P, Bornemann J, Kowalska MA, Gassler N, Streetz KL, Weiskirchen R, Trautwein C, Weber C, Wasmuth HE.
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| Hepatology 51(4):1345-53. doi: 10.1002/hep.23435.
2010
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| 10 | CD163, PF4
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| CXCL4 downregulates the atheroprotective hemoglobin receptor CD163 in human macrophages.
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| Gleissner CA, Shaked I, Erbel C, Böckler D, Katus HA, Ley K.
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| Circ Res 106(1):203-11. doi: 10.1161/CIRCRESAHA.109.199505. Epub 2009 Nov 12.
2010
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| 11 | CAMP, PF4
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| The cathelicidin LL-37 activates human mast cells and is degraded by mast cell tryptase: counter-regulation by CXCL4.
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| Schiemann F, Brandt E, Gross R, Lindner B, Mittelstädt J, Sommerhoff CP, Schulmistrat J, Petersen F.
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| J Immunol 183(4):2223-31. Epub 2009 Jul 22.PMID: 19625657 2009
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| 12 | PF4
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| The CXC-chemokine CXCL4 interacts with integrins implicated in angiogenesis.
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| Aidoudi S, Bujakowska K, Kieffer N, Bikfalvi A.
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| PLoS ONE 3(7):e2657.
2008
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| 13 | PF4
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| Platelet-associated PF-4 as a biomarker of early tumor growth.
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| Cervi D, Yip TT, Bhattacharya N, Podust VN, Peterson J, Abou-Slaybi A, Naumov GN, Bender E, Almog N, Italiano JE Jr, Folkman J, Klement GL.
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| Blood 111(3):1201-7. Epub 2007 Oct 3.
2008
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| 14 | PF4, PF4V1
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| PF-4/CXCL4 and CXCL4L1 exhibit distinct subcellular localization and a differentially regulated mechanism of secretion.
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| Lasagni L, Grepin R, Mazzinghi B, Lazzeri E, Meini C, Sagrinati C, Liotta F, Frosali F, Ronconi E, Alain-Courtois N, Ballerini L, Netti GS, Maggi E, Annunziato F, Serio M, Romagnani S, Bikfalvi A, Romagnani P.
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| Blood 109(10):4127-34. Epub 2007 Jan 11.
2007
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| 15 | PF4
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| CXCL4 in atherosclerosis: possible roles in monocyte arrest and macrophage foam cell formation.
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| Gleissner CA, Ley K.
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| Thromb Haemost 98(5):917-8. No abstract available.
2007
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| 16 | PF4
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| Roles of platelet factor 4 in hematopoiesis and angiogenesis.
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| Maurer AM, Zhou B, Han ZC.
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| Growth Factors 24(4):242-52. Review.
2006
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| 17 | PF4, PF4V1
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| Platelets release CXCL4L1, a nonallelic variant of the chemokine platelet factor-4/CXCL4 and potent inhibitor of angiogenesis.
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| Struyf S, Burdick MD, Proost P, Van Damme J, Strieter RM.
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| Circ Res 95(9):855-7. Epub 2004 Sep 30.
2004
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| 18 | PKNOX1, MEIS1, PF4
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| PREP1, MEIS1 homolog protein, regulates PF4 gene expression.
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| Okada Y, Matsuura E, Nagai R, Sato T, Watanabe A, Morita I, Doi T.
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| Biochem Biophys Res Commun 305(1):155-9. 2003
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| 19 | MEIS1, PBX1, PBX2, PF4
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| Homeodomain proteins MEIS1 and PBXs regulate the lineage-specific transcription of the platelet factor 4 gene.
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| Okada Y, Nagai R, Sato T, Matsuura E, Minami T, Morita I, Doi T.
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| Blood 101(12):4748-56. Epub 2003 Feb 27. 2003
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| 20 | PF4
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| Platelet factor 4 inhibits proliferation and cytokine release of activated human T cells.
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| Fleischer J, Grage-Griebenow E, Kasper B, Heine H, Ernst M, Brandt E, Flad HD, Petersen F.
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| J Immunol 169(2):770-7. 2002
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| 21 | PF4
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| Significantly elevated expression of PF4 (platelet factor 4) and eotaxin in the NOA mouse, a model for atopic dermatitis.
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| Watanabe O, Natori K, Tamari M, Shiomoto Y, Kubo S, Nakamura Y.
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| J Hum Genet 44(3):173-6. 1999
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| 22 | CXCL11, PF4, PPBP
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| Physical mapping of the CXC chemokine locus on human chromosome 4.
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| O'Donovan N, Galvin M, Morgan JG.
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| Cytogenet Cell Genet 84(1-2):39-42. 1999
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| 23 | PF4
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| PF4 inhibits thrombin-stimulated MMP-1 and MMP-3 metalloproteinase expression in human vascular endothelial cells.
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| Klein-Soyer C, Duhamel-Clerin E, Ravanat C, Orvain C, Lanza F, Cazenave JP.
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| C R Acad Sci III 320(11):857-68. 1997
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| 24 | PF4, PF4V1
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| Structural and functional comparison of the genes for human platelet factor 4 and PF4-alt.
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| Eisman R, et al.
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| Blood 76 : 336-344. 1990
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| 25 | PF4
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| Polymerase chain reaction (PCR) for detection of PstI polymorphism in the human PF4 gene.
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| Ramachandran B, et al.
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| Nucleic Acids Res 18 : 5919. 1990
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| 26 | PF4
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| An Eco R1 polymorphism of a human platelet factor 4 (PF4) gene.
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| Guzzo C, et al.
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| Nucleic Acids Res 15 : 380. 1987
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| 27 | PF4, PF4V1
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| Human platelet factor 4 gene is mapped to 4q12-q21.
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| Griffin CA, et al.
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| Cytogenet Cell Genet 45 : 67-69. 1987
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