| 1 | PELI1, RIPK1
|
| PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP.
|
| Wang H, Meng H, Li X, Zhu K, Dong K, Mookhtiar AK, Wei H, Li Y, Sun SC, Yuan J.
|
| Proc Natl Acad Sci U S A 114(45):11944-11949. doi: 10.1073/pnas.1715742114. Epub 2017 Oct 23.
2017
|
| 2 | PELI1
|
| PELI1 expression is correlated with MYC and BCL6 expression and associated with poor prognosis in diffuse large B-cell lymphoma.
|
| Choe JY, Park M, Yun JY, Na HY, Go H, Kim HJ, Oh S, Kim JE.
|
| Mod Pathol 29(11):1313-1323. doi: 10.1038/modpathol.2016.128. Epub 2016 Jul 29.
2016
|
| 3 | PELI1
|
| Peli1 negatively regulates type I interferon induction and antiviral immunity in the CNS.
|
| Xiao Y, Jin J, Zou Q, Hu H, Cheng X, Sun SC.
|
| Cell Biosci 5:34. doi: 10.1186/s13578-015-0024-z. eCollection 2015.
2015
|
| 4 | PELI1
|
| Peli1 negatively regulates type I interferon induction and antiviral immunity in the CNS.
|
| Xiao Y, Jin J, Zou Q, Hu H, Cheng X, Sun SC.
|
| Cell Biosci 5:34. doi: 10.1186/s13578-015-0024-z. eCollection 2015.
2015
|
| 5 | PELI1, PELI2, PELI3
|
| E3 ubiquitin ligases Pellinos as regulators of pattern recognition receptor signaling and immune responses.
|
| Medvedev AE, Murphy M, Zhou H, Li X.
|
| Immunol Rev 266(1):109-22. doi: 10.1111/imr.12298. Review.
2015
|
| 6 | PELI1
|
| Pellino1-mediated TGF-β1 synthesis contributes to mechanical stress induced cardiac fibroblast activation.
|
| Song J, Zhu Y, Li J, Liu J, Gao Y, Ha T, Que L, Liu L, Zhu G, Chen Q, Xu Y, Li C, Li Y.
|
| J Mol Cell Cardiol 79:145-56. doi: 10.1016/j.yjmcc.2014.11.006. Epub 2014 Nov 13.
2015
|
| 7 | PELI1, PELI2, PELI3
|
| The pellino e3 ubiquitin ligases recognize specific phosphothreonine motifs and have distinct substrate specificities.
|
| Huoh YS, Ferguson KM.
|
| Biochemistry 53(30):4946-55. doi: 10.1021/bi5005156. Epub 2014 Jul 16.
2014
|
| 8 | PELI1, PELI2, PELI3
|
| The roles of Pellino E3 ubiquitin ligases in immunity.
|
| Moynagh PN.
|
| Nat Rev Immunol 14(2):122-31. doi: 10.1038/nri3599. Epub 2014 Jan 21. Review.
2014
|
| 9 | BCL6, PELI1
|
| Pellino 1 promotes lymphomagenesis by deregulating BCL6 polyubiquitination.
|
| Park HY, Go H, Song HR, Kim S, Ha GH, Jeon YK, Kim JE, Lee H, Cho H, Kang HC, Chung HY, Kim CW, Chung DH, Lee CW.
|
| J Clin Invest 124(11):4976-88. doi: 10.1172/JCI75667. Epub 2014 Oct 8.
2014
|
| 10 | DEAF1, PELI1
|
| DEAF1 is a Pellino1-interacting protein required for interferon production by Sendai virus and double-stranded RNA.
|
| Ordureau A, Enesa K, Nanda S, Le Francois B, Peggie M, Prescott A, Albert PR, Cohen P.
|
| J Biol Chem 288(34):24569-80. doi: 10.1074/jbc.M113.479550. Epub 2013 Jul 11.
2013
|
| 11 | PELI1, PELI2, PELI3
|
| Pellino 2 is critical for Toll-like receptor/interleukin-1 receptor (TLR/IL-1R)-mediated post-transcriptional control.
|
| Kim TW, Yu M, Zhou H, Cui W, Wang J, DiCorleto P, Fox P, Xiao H, Li X.
|
| J Biol Chem 287(30):25686-95. doi: 10.1074/jbc.M112.352625. Epub 2012 Jun 5.
2012
|
| 12 | PELI1
|
| Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system.
|
| Goh ET, Arthur JS, Cheung PC, Akira S, Toth R, Cohen P.
|
| Biochem J 441(1):339-46. doi: 10.1042/BJ20111415.
2012
|
| 13 | PELI1, TBK1
|
| The role of TBK1 and IKKε in the expression and activation of Pellino 1.
|
| Smith H, Liu XY, Dai L, Goh ET, Chan AT, Xi J, Seh CC, Qureshi IA, Lescar J, Ruedl C, Gourlay R, Morton S, Hough J, McIver EG, Cohen P, Cheung PC.
|
| Biochem J 434(3):537-48. 2011
|
| 14 | PELI1
|
| Pellino-1, an adaptor protein of interleukin-1 receptor/toll-like receptor signaling, is sumoylated by Ubc9.
|
| Kim JH, Sung KS, Jung SM, Lee YS, Kwon JY, Choi CY, Park SH.
|
| Mol Cells 31(1):85-9. Epub 2010 Nov 25.
2011
|
| 15 | IKBKE, PELI1, TBK1
|
| The role of TBK1 and IKKε in the expression and activation of Pellino 1.
|
| Smith H, Liu XY, Dai L, Goh ET, Chan AT, Xi J, Seh CC, Qureshi IA, Lescar J, Ruedl C, Gourlay R, Morton S, Hough J, McIver EG, Cohen P, Cheung PC.
|
| Biochem J 434(3):537-48.
2011
|
| 16 | MIR21, PELI1
|
| MicroRNA-21 is upregulated during the proliferative phase of liver regeneration, targets Pellino-1, and inhibits NF-kappaB signaling.
|
| Marquez RT, Wendlandt E, Galle CS, Keck K, McCaffrey AP.
|
| Am J Physiol Gastrointest Liver Physiol 298(4):G535-41. Epub 2010 Feb 18.
2010
|
| 17 | IRAK1, IRAK4, PELI1, PELI2, PELI3
|
| Identification of the phosphorylation sites on the E3 ubiquitin ligase Pellino that are critical for activation by IRAK1 and IRAK4.
|
| Smith H, Peggie M, Campbell DG, Vandermoere F, Carrick E, Cohen P.
|
| Proc Natl Acad Sci U S A 106(12):4584-90. Epub 2009 Mar 5.
2009
|
| 18 | PELI1
|
| Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production.
|
| Chang M, Jin W, Sun SC.
|
| Nat Immunol 10(10):1089-95. Epub 2009 Sep 6.
2009
|
| 19 | PELI1
|
| Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1.
|
| Lin CC, Huoh YS, Schmitz KR, Jensen LE, Ferguson KM.
|
| Structure 16(12):1806-16.
2008
|
| 20 | PELI1
|
| The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1.
|
| Ordureau A, Smith H, Windheim M, Peggie M, Carrick E, Morrice N, Cohen P.
|
| Biochem J 409(1):43-52.
2008
|
| 21 | PELI1, PELI2, PELI3
|
| Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1.
|
| Lin CC, Huoh YS, Schmitz KR, Jensen LE, Ferguson KM.
|
| Structure 16(12):1806-16. doi: 10.1016/j.str.2008.09.011.
2008
|
| 22 | PELI1, PELI2, PELI3, IRAK1, IRAK4
|
| Kinase-active interleukin-1 receptor-associated kinases promote polyubiquitination and degradation of the Pellino family: direct evidence for PELLINO proteins being ubiquitin-protein isopeptide ligases.
|
| Butler MP, Hanly JA, Moynagh PN.
|
| J Biol Chem 282(41):29729-37. Epub 2007 Aug 3. 2007
|
| 23 | IRAK1, IRAK2, IRAK4, PELI1, PELI2, PELI3
|
| Kinase-active interleukin-1 receptor-associated kinases promote polyubiquitination and degradation of the Pellino family: direct evidence for PELLINO proteins being ubiquitin-protein isopeptide ligases.
|
| Butler MP, Hanly JA, Moynagh PN.
|
| J Biol Chem 282(41):29729-37. Epub 2007 Aug 3.
2007
|
| 24 | PELI1, PELI2, PELI3, IRAK1
|
| Pellino proteins are more than scaffold proteins in TLR/IL-1R signalling: a role as novel RING E3-ubiquitin-ligases.
|
| Schauvliege R, Janssens S, Beyaert R.
|
| FEBS Lett 580(19):4697-702. Epub 2006 Jul 24. 2006
|
| 25 | PELI1, SMAD6
|
| Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1.
|
| Choi KC, Lee YS, Lim S, Choi HK, Lee CH, Lee EK, Hong S, Kim IH, Kim SJ, Park SH.
|
| Nat Immunol 7(10):1057-65. Epub 2006 Sep 3.
2006
|
| 26 | PELI1, PELI2
|
| Assignment of homologous genes, Peli1/PELI1 and Peli2/PELI2, for the Pelle adaptor protein Pellino to mouse chromosomes 11 and 14 and human chromosomes 2p13.3 and 14q21, respectively, by physical and radiation hybrid mapping.
|
| Resch K, Jockusch H, Schmitt-John T.
|
| Cytogenet Cell Genet 92(1-2):172-4. No abstract available. 2001
|
| 27 | PELI1
|
| Pellino-related sequences from Caenorhabditis elegans and Homo sapiens.
|
| Rich T, Allen RL, Lucas AM, Stewart A, Trowsdale J.
|
| Immunogenetics 52(1-2):145-9. No abstract available. 2000
|