Citations for
1PDZK1, SLC1A5
Transport mechanism and regulatory properties of the human amino acid transporter ASCT2 (SLC1A5).
Scalise M, Pochini L, Panni S, Pingitore P, Hedfalk K, Indiveri C.
Amino Acids 46(11):2463-75. doi: 10.1007/s00726-014-1808-x. Epub 2014 Jul 23. 2014
2PDZK1, SLC9A3R1, SLCO1A2
PDZK1 and NHERF1 regulate the function of human organic anion transporting polypeptide 1A2 (OATP1A2) by modulating its subcellular trafficking and stability.
Zheng J, Chan T, Cheung FS, Zhu L, Murray M, Zhou F.
PLoS One 9(4):e94712. doi: 10.1371/journal.pone.0094712. eCollection 2014. 2014
3ESR1, IGF1R, PDZK1
PDZK1 is a novel factor in breast cancer that is indirectly regulated by estrogen through IGF-1R and promotes estrogen-mediated growth.
Kim H, Abd Elmageed ZY, Ju J, Naura AS, Abdel-Mageed AB, Varughese S, Paul D, Alahari S, Catling A, Kim JG, Boulares AH.
Mol Med 19:253-62. doi: 10.2119/molmed.2011.00001. 2013
4PDZK1, SLC34A2, SLC9A3R1
NHE3 regulatory factor 1 (NHERF1) modulates intestinal sodium-dependent phosphate transporter (NaPi-2b) expression in apical microvilli.
Giral H, Cranston D, Lanzano L, Caldas Y, Sutherland E, Rachelson J, Dobrinskikh E, Weinman EJ, Doctor RB, Gratton E, Levi M.
J Biol Chem 287(42):35047-56. doi: 10.1074/jbc.M112.392415. Epub 2012 Aug 17. 2012
5PDZK1, SLC34A3
Role of PDZK1 protein in apical membrane expression of renal sodium-coupled phosphate transporters.
Giral H, Lanzano L, Caldas Y, Blaine J, Verlander JW, Lei T, Gratton E, Levi M.
J Biol Chem 286(17):15032-42. Epub 2011 Mar 9. 2011
6PDZK1, PTGIR
Interaction of the human prostacyclin receptor with the PDZ adapter protein PDZK1: role in endothelial cell migration and angiogenesis.
Turner EC, Mulvaney EP, Reid HM, Kinsella BT.
Mol Biol Cell 22(15):2664-79. Epub 2011 Jun 8. 2011
7PDZK1, PTGIR
Interaction of the human prostacyclin receptor with the PDZ adapter protein PDZK1: role in endothelial cell migration and angiogenesis.
Turner EC, Mulvaney EP, Reid HM, Kinsella BT.
Mol Biol Cell. 22(15):2664-79 2011
8PDZK1, SCARB1
The SR-BI partner PDZK1 facilitates hepatitis C virus entry.
Eyre NS, Drummer HE, Beard MR.
PLoS Pathog 6(10):e1001130. 2010
9PDZK1, SLC9A3R1
A regulated complex of the scaffolding proteins PDZK1 and EBP50 with ezrin contribute to microvillar organization.
LaLonde DP, Garbett D, Bretscher A.
Mol Biol Cell 21(9):1519-29. Epub 2010 Mar 17. 2010
10PDZK1, SLC9A3
NHERF3 (PDZK1) contributes to basal and calcium inhibition of NHE3 activity in Caco-2BBe cells.
Zachos NC, Li X, Kovbasnjuk O, Hogema B, Sarker R, Lee LJ, Li M, de Jonge H, Donowitz M.
J Biol Chem 284(35):23708-18. Epub 2009 Jun 17. 2009
11CFTR, PDZK1, SLC9A3R1, SLC9A3R2
Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.
Singh AK, Riederer B, Krabbenhöft A, Rausch B, Bonhagen J, Lehmann U, de Jonge HR, Donowitz M, Yun C, Weinman EJ, Kocher O, Hogema BM, Seidler U.
J Clin Invest 119(3):540-50. doi: 10.1172/JCI35541. Epub 2009 Feb 16. 2009
12PDZK1, SLC9A3R1
The scaffold protein PDZK1 undergoes a head-to-tail intramolecular association that negatively regulates its interaction with EBP50.
LaLonde DP, Bretscher A.
Biochemistry 48(10):2261-71. 2009
13PDZK1, PPARA
Regulation of the human PDZK1 expression by peroxisome proliferator-activated receptor alpha.
Tachibana K, Anzai N, Ueda C, Katayama T, Yamasaki D, Kirino T, Takahashi R, Ishimoto K, Komori H, Tanaka T, Hamakubo T, Ueda Y, Arai H, Sakai J, Kodama T, Doi T.
FEBS Lett 582(28):3884-8. Epub 2008 Oct 26. 2008
14PDZK1
The scavenger receptor class B type I adaptor protein PDZK1 maintains endothelial monolayer integrity.
Zhu W, Saddar S, Seetharam D, Chambliss KL, Longoria C, Silver DL, Yuhanna IS, Shaul PW, Mineo C.
Circ Res 102(4):480-7. Epub 2008 Jan 3.PMID: 18174467 2008
15PDZK1
Influence of PDZK1 on lipoprotein metabolism and atherosclerosis.
Kocher O, Yesilaltay A, Shen CH, Zhang S, Daniels K, Pal R, Chen J, Krieger M.
Biochim Biophys Acta 1782(5):310-6. Epub 2008 Mar 10.PMID: 18342019 2008
16PDZK1, SCARB1
PDZK1 is required for maintaining hepatic scavenger receptor, class B, type I (SR-BI) steady state levels but not its surface localization or function.
Yesilaltay A, Kocher O, Pal R, Leiva A, Qui–ones V, Rigotti A, Krieger M.
J Biol Chem 281(39):28975-80. Epub 2006 Jul 25. 2006
17SLC15A2, PDZK1
The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity.
Noshiro R, Anzai N, Sakata T, Miyazaki H, Terada T, Shin HJ, He X, Miura D, Inui K, Kanai Y, Endou H.
Kidney Int 70(2):275-82. Epub 2006 May 31. 2006
18PDZK1, SCARB1
Regulation of SR-BI protein levels by phosphorylation of its associated protein, PDZK1.
Nakamura T, Shibata N, Nishimoto-Shibata T, Feng D, Ikemoto M, Motojima K, Iso-O N, Tsukamoto K, Tsujimoto M, Arai H.
Proc Natl Acad Sci U S A 102(38):13404-9. Epub 2005 Sep 8. 2005
19GOPC, PDZK1, SSTR5
Interactions with PDZ domain proteins PIST/GOPC and PDZK1 regulate intracellular sorting of the somatostatin receptor subtype 5.
Wente W, Stroh T, Beaudet A, Richter D, Kreienkamp HJ.
J Biol Chem 280(37):32419-25. Epub 2005 Jul 12. 2005
20SLCO4A1, PDZK1
Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface.
Wang P, Wang JJ, Xiao Y, Murray JW, Novikoff PM, Angeletti RH, Orr GA, Lan D, Silver DL, Wolkoff AW.
J Biol Chem 280(34):30143-9. Epub 2005 Jun 30. 2005
21PDZK1, SLC22A5
PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2.
Kato Y, Sai Y, Yoshida K, Watanabe C, Hirata T, Tsuji A.
Mol Pharmacol. 67(3):734-43. 2005
22PDZK1
The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus.
Anzai N, Miyazaki H, Noshiro R, Khamdang S, Chairoungdua A, Shin HJ, Enomoto A, Sakamoto S, Hirata T, Tomita K, Kanai Y, Endou H.
J Biol Chem 279(44):45942-50. Epub 2004 Aug 10. 2004
23PDZK1
Screening of the interaction between xenobiotic transporters and PDZ proteins.
Kato Y, Yoshida K, Watanabe C, Sai Y, Tsuji A.
Pharm Res. 21(10):1886-94. 2004
24PDZK1, PDZK1IP1
Identification of small PDZK1-associated protein, DD96/MAP17, as a regulator of PDZK1 and plasma high density lipoprotein levels.
Silver DL, Wang N, Vogel S.
J Biol Chem 278(31):28528-32. Epub 2003 May 15. 2003
25PDZK1, AKAP10
PDZK1: II. an anchoring site for the PKA-binding protein D-AKAP2 in renal proximal tubular cells.
Gisler SM, Madjdpour C, Bacic D, Pribanic S, Taylor SS, Biber J, Murer H.
Kidney Int 64(5):1746-54. 2003
26PDZK1, SLC17A1, SLC9A3R1
PDZK1: I. a major scaffolder in brush borders of proximal tubular cells.
Gisler SM, Pribanic S, Bacic D, Forrer P, Gantenbein A, Sabourin LA, Tsuji A, Zhao ZS, Manser E, Biber J, Murer H.
Kidney Int 64(5):1733-45. 2003
27PDZK1
The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins.
Gentzsch M, Cui L, Mengos A, Chang XB, Chen JH, Riordan JR.
J Biol Chem. 278(8):6440-9. 2003
28PDZK1
Targeted disruption of the PDZK1 gene in mice causes tissue-specific depletion of the high density lipoprotein receptor scavenger receptor class B type I and altered lipoprotein metabolism.
Kocher O, Yesilaltay A, Cirovic C, Pal R, Rigotti A, Krieger M.
J Biol Chem. 278(52):52820-5. 2003
29PDZK1
A carboxyl-terminal PDZ-interacting domain of scavenger receptor B, type I is essential for cell surface expression in liver.
Silver DL.
J Biol Chem. 277(37):34042-7. 2002
30GREB1, PDZK1
PDZK1 and GREB1 are estrogen-regulated genes expressed in hormone-responsive breast cancer.
Ghosh MG, Thompson DA, Weigel RJ.
Cancer Res 60(22):6367-75. 2000
31PDZK1
PDZK1, a novel PDZ domain-containing protein up-regulated in carcinomas and mapped to chromosome 1q21, interacts with cMOAT (MRP2), the multidrug resistance-associated protein.
Kocher O, Comella N, Gilchrist A, Pal R, Tognazzi K, Brown LF, Knoll JH.
Lab Invest. 79(9):1161-70. 1999
32PDZK1
A PDZ domain-containing protein with homology to Diphor-1 maps to human chromosome 1q21.
White KE, et al.
Ann Hum Genet 62 : 287-290. 1998
33PDZK1
Identifcation of a new gene product (diphor-1) regulated by dietary phosphate.
Custer M, et al.
Am J Physiol 273 : F801-F806. 1997