1 | PDGFA, PDGFRA
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| PDGF controls contact inhibition of locomotion by regulating N-cadherin during neural crest migration.
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| Bahm I, Barriga EH, Frolov A, Theveneau E, Frankel P, Mayor R.
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| Development 144(13):2456-2468. doi: 10.1242/dev.147926. Epub 2017 May 19.
2017
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2 | PDGFA
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| Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis.
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| Rivera-Gonzalez GC, Shook BA, Andrae J, Holtrup B, Bollag K, Betsholtz C, Rodeheffer MS, Horsley V.
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| Cell Stem Cell 19(6):738-751. doi: 10.1016/j.stem.2016.09.002. Epub 2016 Oct 13.
2016
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3 | DUOX1, DUOX2, NOX4, PDGFA
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| Nox4 and Duox1/2 Mediate Redox Activation of Mesenchymal Cell Migration by PDGF.
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| Tyurin-Kuzmin PA, Zhdanovskaya ND, Sukhova AA, Sagaradze GD, Albert EA, Ageeva LV, Sharonov GV, Vorotnikov AV, Tkachuk VA.
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| PLoS One 11(4):e0154157. doi: 10.1371/journal.pone.0154157. eCollection 2016. 2016
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4 | PDGFA
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| Expression and function of PDGF-α in columnar epithelial cells of age-related cataracts patients.
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| Wei J, Tang H, Xu ZQ, Li B, Xie LQ, Xu GX.
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| Genet Mol Res 14(4):13320-7. doi: 10.4238/2015.October.26.28.
2015
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5 | PDGFA, TGFB1
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| Platelet-Derived Growth Factor and Transforming Growth Factor β1 Regulate ARDS-Associated Lung Fibrosis Through Distinct Signaling Pathways.
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| Deng X, Jin K, Li Y, Gu W, Liu M, Zhou L.
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| Cell Physiol Biochem 36(3):937-46. doi: 10.1159/000430268. Epub 2015 Jun 12.
2015
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6 | GIT1, PDGFA
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| Regulation of chondrocyte proliferation through GIT1-Rac1-mediated ERK1/2 pathway by PDGF.
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| Xiao J, Chen X, Xu L, Zhang Y, Yin Q, Wang F.
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| Cell Biol Int ell Biol Int. 2014 Jan 13. doi: 10.1002/cbin.10241. [Epub ahead of print]
2014
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7 | MRTFA, PDGFA, SRF
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| SRF regulates craniofacial development through selective recruitment of MRTF cofactors by PDGF signaling.
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| Vasudevan HN, Soriano P.
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| Dev Cell 31(3):332-44. doi: 10.1016/j.devcel.2014.10.005. Epub 2014 Nov 10. 2014
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8 | PDGFA, SOX11
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| SOX11 promotes tumor angiogenesis through transcriptional regulation of PDGFA in mantle cell lymphoma.
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| Palomero J, Vegliante MC, Rodríguez ML, Eguileor A, Castellano G, Planas-Rigol E, Jares P, Ribera-Cortada I, Cid MC, Campo E, Amador V.
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| Blood 124(14):2235-47. doi: 10.1182/blood-2014-04-569566. Epub 2014 Aug 4.
2014
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9 | EZR, MSN, PDGFA, RDX
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| Redundant control of migration and adhesion by ERM proteins in vascular smooth muscle cells.
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| Baeyens N, Latrache I, Yerna X, Noppe G, Horman S, Morel N.
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| Biochem Biophys Res Commun 441(3):579-85. doi: 10.1016/j.bbrc.2013.10.118. Epub 2013 Oct 30.
2013
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10 | PDGFA
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| BMP-specific SMADs function as novel repressors of PDGFA and modulate its expression in ovarian granulosa cells and tumors.
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| Tripurani SK, Cook RW, Eldin KW, Pangas SA.
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| Oncogene 32(33):3877-85. doi: 10.1038/onc.2012.392. Epub 2012 Sep 10.
2013
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11 | IL13, PDGFA
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| Oxidant signaling for interleukin-13 gene expression in lung smooth muscle cells.
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| Bansal G, Wong CM, Liu L, Suzuki YJ.
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| Free Radic Biol Med 52(9):1552-9. Epub 2012 Feb 25. 2012
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12 | MUC1, PDGFA
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| MUC1 regulates PDGFA expression during pancreatic cancer progression.
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| Sahraei M, Roy LD, Curry JM, Teresa TL, Nath S, Besmer D, Kidiyoor A, Dalia R, Gendler SJ, Mukherjee P.
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| Oncogene 31(47):4935-45. doi: 10.1038/onc.2011.651. Epub 2012 Jan 23.
2012
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13 | CDKN2A, EZH2, PDGFA, PDGFRA, PDGFRB
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| PDGF signalling controls age-dependent proliferation in pancreatic β-cells.
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| Chen H, Gu X, Liu Y, Wang J, Wirt SE, Bottino R, Schorle H, Sage J, Kim SK.
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| Nature 478(7369):349-55. doi: 10.1038/nature10502.
2011
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14 | PDGFA, PEA15, PLCG1
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| A phospholipase Cγ1-activated pathway regulates transcription in human vascular smooth muscle cells.
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| Hunter I, Mascall KS, Ramos JW, Nixon GF.
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| Cardiovasc Res 90(3):557-64. doi: 10.1093/cvr/cvr039. Epub 2011 Feb 1.
2011
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15 | ENAH, PDGFA, WASF2, WASL
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| WAVE2, N-WASP, and Mena facilitate cell invasion via phosphatidylinositol 3-kinase-dependent local accumulation of actin filaments.
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| Takahashi K, Suzuki K.
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| J Cell Biochem 112(11):3421-9. doi: 10.1002/jcb.23276.
2011
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16 | MTSS2, PDGFA, RAC1
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| Abba promotes PDGF-mediated membrane ruffling through activation of the small GTPase Rac1.
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| Zheng D, Niu S, Yu D, Zhan XH, Zeng X, Cui B, Chen Y, Yoon J, Martin SS, Lu X, Zhan X.
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| Biochem Biophys Res Commun 401(4):527-32. Epub 2010 Sep 26. 2010
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17 | PDGFA, PDGFRA
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| Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas.
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| Martinho O, Longatto-Filho A, Lambros MB, Martins A, Pinheiro C, Silva A, Pardal F, Amorim J, Mackay A, Milanezi F, Tamber N, Fenwick K, Ashworth A, Reis-Filho JS, Lopes JM, Reis RM.
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| Br J Cancer 101(6):973-82. Epub 2009 Aug 25.
2009
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18 | KDR, PDGFA, VEGFA
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| 2: A role for VEGF as a negative regulator of pericyte function and vessel maturation.
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| Greenberg JI, Shields DJ, Barillas SG, Acevedo LM, Murphy E, Huang J, Scheppke L, Stockmann C, Johnson RS, Angle N, Cheresh DA.
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| Nature 456(7223):809-13. Epub 2008 Nov 9. Erratum in: Nature. 2009 Feb 26;457(7233):1168.
2008
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19 | PDGFA
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| PDGF signalling controls the migration of mesoderm cells during chick gastrulation by regulating N-cadherin expression.
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| Yang X, Chrisman H, Weijer CJ.
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| Development 135(21):3521-30. Epub 2008 Oct 2.PMID: 18832396 2008
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20 | PDGFA
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| Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression.
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| Yamamoto S, Fukumoto E, Yoshizaki K, Iwamoto T, Yamada A, Tanaka K, Suzuki H, Aizawa S, Arakaki M, Yuasa K, Oka K, Chai Y, Nonaka K, Fukumoto S.
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| J Biol Chem 283(34):23139-49. Epub 2008 Jun 17.PMID: 18559345 2008
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21 | PDGFA
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| PDGF-A as an epicardial mitogen during heart development.
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| Kang J, Gu Y, Li P, Johnson BL, Sucov HM, Thomas PS.
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| Dev Dyn 237(3):692-701.PMID: 18297729 2008
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22 | PDGFA, PDGFB, PDGFRA, PDGFRB
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| Platelet-derived growth factors (PDGF-A and -B) and their receptors in human fetal and adult ovaries.
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| Pinkas H, Fisch B, Rozansky G, Felz C, Kessler-Icekson G, Krissi H, Nitke S, Ao A, Abir R.
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| Mol Hum Reprod 14(4):199-206. Epub 2008 Mar 7.PMID: 18326546 2008
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23 | ABCA1,PDGFA
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| Platelet derived growth factor regulates ABCA1 expression in vascular smooth muscle cells.
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| Nagao S, Murao K, Imachi H, Cao WM, Yu X, Li J, Matsumoto K, Nishiuchi T, Ahmed RA, Wong NC, Ueda K, Ishida T.
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| FEBS Lett 580(18):4371-6. Epub 2006 Jul 10. 2006
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24 | PDGFA, PDGFC
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| A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling.
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| Ding H, Wu X, Bostrom H, Kim I, Wong N, Tsoi B, O'Rourke M, Koh GY, Soriano P, Betsholtz C, Hart TC, Marazita ML, Field LL, Tam PP, Nagy A.
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| Nat Genet 36(10):1111-6. Epub 2004 Sep 07. 2004
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25 | ADRA2A, ADRB1, AGTR1, CAFG, CD36, CETP, CSF1, CSF2, CYP11B2, ECE1, EDN1, EDNRA, EDNRB, EGR1, F2R, FGA, FGB, FHBL1, HGF, ICAM1, IGF1, IL1A, IL6, LPA, MGP, MSR1, MTTP, NOS2, NOS3, PDGFA, PDGFRA, SELP, TGFB1, TNF, VCAM1, VDR
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| Sequence diversity in 36 candidate genes for cardiovascular disorders.
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| Cambien F, Poirier O, Nicaud V, Herrmann SM, Mallet C, Ricard S, Behague I, Hallet V, Blanc H, Loukaci V, Thillet J, Evans A, Ruidavets JB, Arveiler D, Luc G, Tiret L.
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| Am J Hum Genet 65(1):183-91. 1999
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26 | PDGFA
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| Platelet-derived growth factor A chain : confirmation of localization of PDGFA to chromosome 7p22 and description of an unusual minisatellite.
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| Bonthron D, et al.
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| Genomics 13 : 257-263. 1992
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27 | PDGFA
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| The human platelet-derived growth factor alpha chain (PDGFA) gene maps to chromosome 7p22.
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| Stenman G, et al.
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| Cytogenet Cell Genet 60 : 206-207. 1992
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28 | PDGFA
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| Platelet-derived growth factor (PDGF) A-chain mRNA heterogeneity generated by the use of alternative promoters and alternative polyadenylation sites.
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| Rorsman F, et al.
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| Growth Factors 7 : 241-251. 1992
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29 | PDGFA, PDGFB
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| Platelet-derived growth factor gene expression in cultured human retinal pigment epithelial cells.
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| Yoshida M, et al.
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| Biochem Biophys Res Commun 189 : 66-71. 1992
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30 | PDGFA
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| Expression cloning of a human dual-specificity phosphatase.
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| Ishibashi T, Bottaro DP, Chan A, Miki T, Aaronson SA.
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| Proc Natl Acad Sci U S A 89(24):12170-4.PMID: 1281549 1992
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31 | PDGFA
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| Confirmation of PDGFA localization to 7p21-p22.
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| Speleman F, et al.
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| Am J Hum Genet 49S : 375. 1991
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32 | PDGFA
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| Styl RFLP of the human platelet derived growth factor (PDGF) A-chain gene.
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| Ferns GAA, et al.
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| Nucleic Acids Res 18 : 208. 1990
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33 | PDGFA
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| HindIII polymorphism in the human c-sis proto-oncogene.
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| Fourney RM, Dietrich KD, Aubin RA, Paterson MC.
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| Nucleic Acids Res 16 : 8197. 1988
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34 | PDGFA
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| Platelet-derived growth factor A chain: Gene structure, chromosomal location, and basis for alternative mRNA splicing.
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| Bonthron DT, et al.
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| Proc Natl Acad Sci U S A 85 : 1492-1496. 1988
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35 | PDGFA
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| Sublocalization of the human PDGF A-chain gene to chromosome 7, band q11.23, by in situ hybridization.
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| Stenman G, et al.
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| Exp Cell Res 178 : 180-184. 1988
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36 | PDGFA
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| cDNA clones reveal differences between human glial and endothelial cell platelet-derived growth factor A-chains.
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| Tong BD, et al.
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| Nature 328 : 619-621. 1987
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37 | PDGFA
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| Alternative RNA splicing affects function of encoded platelet-derived growth factor A chain.
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| Collins T, Bonthron DT, Orkin SH.
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| Nature 328 : 621-624. 1987
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38 | PDGFA
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| Platelet-derived growth factor A chain is assigned to 7p22-p21.
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| Morton CC, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 664. 1987
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39 | EPO, LAMB1, PDGFA
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| Mapping PDGFA, EPO, and LAMB1 to specific sites on chromosome 7q.
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| Fukushima Y, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 616. 1987
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40 | PDGFA
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| cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumor cell lines.
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| Betsholtz C, et al.
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| Nature 320 : 695-699. 1986
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