Citations for
Insight into binding of phosphodiesterase-9A selective inhibitors by crystal structures and mutagenesis.
Wang H, Luo X, Ye M, Hou J, Robinson H, Ke H.
J Med Chem 53(4):1726-31.PMID: 20121115 2010
PDE9A, PDE10A, and PDE11A expression in rat trigeminovascular pain signalling system.
Kruse LS, Møller M, Tibaek M, Gammeltoft S, Olesen J, Kruuse C.
Brain Res 1281:25-34. Epub 2009 May 13.PMID: 19445908 2009
Identification of a brain penetrant PDE9A inhibitor utilizing prospective design and chemical enablement as a rapid lead optimization strategy.
Verhoest PR, Proulx-Lafrance C, Corman M, Chenard L, Helal CJ, Hou X, Kleiman R, Liu S, Marr E, Menniti FS, Schmidt CJ, Vanase-Frawley M, Schmidt AW, Williams RD, Nelson FR, Fonseca KR, Liras S.
J Med Chem 52(24):7946-9.PMID: 19919087 2009
Structural basis for the catalytic mechanism of human phosphodiesterase 9.
Liu S, Mansour MN, Dillman KS, Perez JR, Danley DE, Aeed PA, Simons SP, Lemotte PK, Menniti FS.
Proc Natl Acad Sci U S A 105(36):13309-14. Epub 2008 Aug 29. 2008
High expression of the cGMP-specific phosphodiesterase, PDE9A, in sickle cell disease (SCD) and the effects of its inhibition in erythroid cells and SCD neutrophils.
Almeida CB, Traina F, Lanaro C, Canalli AA, Saad ST, Costa FF, Conran N.
Br J Haematol 142(5):836-44. Epub 2008 Jun 17.PMID: 18564357 2008
Expression of the cGMP-specific phosphodiesterases 2 and 9 in normal and Alzheimer's disease human brains.
Reyes-Irisarri E, Markerink-Van Ittersum M, Mengod G, de Vente J.
Eur J Neurosci 25(11):3332-8.PMID: 17553001 2007
T3JAM, a novel protein that specifically interacts with TRAF3 and promotes the activation of JNK(1).
Dadgostar H, Doyle SE, Shahangian A, Garcia DE, Cheng G.
FEBS Lett 553(3):403-7. 2003
Identification and characterization of a new human type 9 cGMP-specific phosphodiesterase splice variant (PDE9A5). Differential tissue distribution and subcellular localization of PDE9A variants.
Wang P, Wu P, Egan RW, Billah MM.
Gene 314:15-27. 2003
Characterization of human chromosome 21q22.3 genes starting from trapped exons.
Michaud J, Bartoloni L, Guipponi M, Wattenhofer M, Chen H, Lalioti MD, Rossier C, Antonarakis SE, Scott HS.
Cytogenet Cell Genet 86:18 1999
Identification and characterization of a novel family of cyclic nucleotide phosphodiesterases.
Soderling SH, Bayuga SJ, Beavo JA.
J Biol Chem 273(25):15553-8. 1998
Identification and characterization of a novel cyclic nucleotide phosphodiesterase gene (PDE9A) that maps to 21q22.3: alternative splicing of mRNA transcripts, genomic structure and sequence.
Guipponi M, Scott HS, Kudoh J, Kawasaki K, Shibuya K, Shintani A, Asakawa S, Chen H, Lalioti MD, Rossier C, Minoshima S, Shimizu N, Antonarakis SE.
Hum Genet 103(4):386-92. 1998