1 | PDCD6, SEC31A
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| Structural analysis of the complex between penta-EF-hand ALG-2 protein and Sec31A peptide reveals a novel target recognition mechanism of ALG-2.
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| Takahashi T, Kojima K, Zhang W, Sasaki K, Ito M, Suzuki H, Kawasaki M, Wakatsuki S, Takahara T, Shibata H, Maki M.
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| Int J Mol Sci 16(2):3677-99. doi: 10.3390/ijms16023677.
2015
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2 | ANXA11, PDCD6, SEC31A
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| A new role for annexin A11 in the early secretory pathway via stabilizing Sec31A protein at the endoplasmic reticulum exit sites (ERES).
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| Shibata H, Kanadome T, Sugiura H, Yokoyama T, Yamamuro M, Moss SE, Maki M.
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| J Biol Chem 290(8):4981-93. doi: 10.1074/jbc.M114.592089. Epub 2014 Dec 24.
2015
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3 | PDCD6, SEC31A
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| Apoptosis-linked gene-2 (ALG-2)/Sec31 interactions regulate endoplasmic reticulum (ER)-to-Golgi transport: a potential effector pathway for luminal calcium.
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| Helm JR, Bentley M, Thorsen KD, Wang T, Foltz L, Oorschot V, Klumperman J, Hay JC.
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| J Biol Chem 289(34):23609-28. doi: 10.1074/jbc.M114.561829. Epub 2014 Jul 8.
2014
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4 | PDCD6, SEC31A
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| ALG-2 attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A complex.
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| la Cour JM, Schindler AJ, Berchtold MW, Schekman R.
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| PLoS One 8(9):e75309. doi: 10.1371/journal.pone.0075309. eCollection 2013.
2013
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5 | PDCD6, RBM22, SLU7
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| Stress induced subcellular distribution of ALG-2, RBM22 and hSlu7.
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| Janowicz A, Michalak M, Krebs J.
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| Biochim Biophys Acta 1813(5):1045-9. doi: 10.1016/j.bbamcr.2010.11.010. Epub 2010 Nov 29.
2011
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6 | CASP9, PDCD6, PDCD6IP, SHISA5
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| Alix is involved in caspase 9 activation during calcium-induced apoptosis.
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| Strappazzon F, Torch S, Chatellard-Causse C, Petiot A, Thibert C, Blot B, Verna JM, Sadoul R.
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| Biochem Biophys Res Commun 397(1):64-9. Epub 2010 May 21.PMID: 20471954 2010
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7 | ALG2, PDCD6, PDCD6IP, TSG101
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| Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101.
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| Okumura M, Ichioka F, Kobayashi R, Suzuki H, Yoshida H, Shibata H, Maki M.
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| Biochem Biophys Res Commun 386(1):237-41. Epub 2009 Jun 9. 2009
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8 | MCOLN1, PDCD6
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| Identification of the penta-EF-hand protein ALG-2 as a Ca2+-dependent interactor of mucolipin-1.
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| Vergarajauregui S, Martina JA, Puertollano R.
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| J Biol Chem 284(52):36357-66. Epub 2009 Oct 28.PMID: 19864416 2009
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9 | ALG2, PDCD6, PDCD6IP
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| Alix and ALG-2 are involved in tumor necrosis factor receptor 1-induced cell death.
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| Mahul-Mellier AL, Strappazzon F, Petiot A, Chatellard-Causse C, Torch S, Blot B, Freeman K, Kuhn L, Garin J, Verna JM, Fraboulet S, Sadoul R.
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| J Biol Chem 283(50):34954-65. Epub 2008 Oct 20. 2008
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10 | PDCD6, PDCD6IP
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| Structural basis for Ca2+ -dependent formation of ALG-2/Alix peptide complex: Ca2+/EF3-driven arginine switch mechanism.
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| Suzuki H, Kawasaki M, Inuzuka T, Okumura M, Kakiuchi T, Shibata H, Wakatsuki S, Maki M.
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| Structure 16(10):1562-73.PMID: 18940611 2008
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11 | SEC31A, PDCD6, PDCD6IP
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| ALG-2 directly binds Sec31A and localizes at endoplasmic reticulum exit sites in a Ca2+-dependent manner.
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| Shibata H, Suzuki H, Yoshida H, Maki M.
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| Biochem Biophys Res Commun 353(3):756-63. Epub 2006 Dec 22. 2007
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12 | PDCD6, SEC31A
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| The Ca2+-binding protein ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization of Sec31A.
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| Yamasaki A, Tani K, Yamamoto A, Kitamura N, Komada M.
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| Mol Biol Cell 17(11):4876-87. Epub 2006 Sep 6. 2006
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13 | PDCD6, RBM22
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| Nuclear translocation of the calcium-binding protein ALG-2 induced by the RNA-binding protein RBM22.
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| Montaville P, Dai Y, Cheung CY, Giller K, Becker S, Michalak M, Webb SE, Miller AL, Krebs J.
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| Biochim Biophys Acta 1763(11):1335-43. Epub 2006 Sep 14.
2006
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14 | PDCD6, PDCD6IP
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| Alix, a protein regulating endosomal trafficking, is involved in neuronal death.
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| Trioulier Y, Torch S, Blot B, Cristina N, Chatellard-Causse C, Verna JM, Sadoul R.
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| J Biol Chem 279(3):2046-52. Epub 2003 Oct 29. 2004
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15 | PDCD6, ANXA11
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| The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent manner.
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| Satoh H, Nakano Y, Shibata H, Maki M.
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| Biochim Biophys Acta 1600(1-2):61-7. 2002
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16 | PDCD6, PEF1
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| Peflin and ALG-2, members of the penta-EF-hand protein family, form a heterodimer that dissociates in a Ca2+-dependent manner.
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| Kitaura Y, Matsumoto S, Satoh H, Hitomi K, Maki M.
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| J Biol Chem 276(17):14053-8. 2001
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17 | PDCD6
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| Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3.
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| Vito P, Lacana E, D'Adamio L.
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| Science 271(5248):521-5 1996
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