Citations for
1PDCD6, SEC31A
Structural analysis of the complex between penta-EF-hand ALG-2 protein and Sec31A peptide reveals a novel target recognition mechanism of ALG-2.
Takahashi T, Kojima K, Zhang W, Sasaki K, Ito M, Suzuki H, Kawasaki M, Wakatsuki S, Takahara T, Shibata H, Maki M.
Int J Mol Sci 16(2):3677-99. doi: 10.3390/ijms16023677. 2015
2ANXA11, PDCD6, SEC31A
A new role for annexin A11 in the early secretory pathway via stabilizing Sec31A protein at the endoplasmic reticulum exit sites (ERES).
Shibata H, Kanadome T, Sugiura H, Yokoyama T, Yamamuro M, Moss SE, Maki M.
J Biol Chem 290(8):4981-93. doi: 10.1074/jbc.M114.592089. Epub 2014 Dec 24. 2015
3PDCD6, SEC31A
Apoptosis-linked gene-2 (ALG-2)/Sec31 interactions regulate endoplasmic reticulum (ER)-to-Golgi transport: a potential effector pathway for luminal calcium.
Helm JR, Bentley M, Thorsen KD, Wang T, Foltz L, Oorschot V, Klumperman J, Hay JC.
J Biol Chem 289(34):23609-28. doi: 10.1074/jbc.M114.561829. Epub 2014 Jul 8. 2014
4PDCD6, SEC31A
ALG-2 attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A complex.
la Cour JM, Schindler AJ, Berchtold MW, Schekman R.
PLoS One 8(9):e75309. doi: 10.1371/journal.pone.0075309. eCollection 2013. 2013
5PDCD6, RBM22, SLU7
Stress induced subcellular distribution of ALG-2, RBM22 and hSlu7.
Janowicz A, Michalak M, Krebs J.
Biochim Biophys Acta 1813(5):1045-9. doi: 10.1016/j.bbamcr.2010.11.010. Epub 2010 Nov 29. 2011
6CASP9, PDCD6, PDCD6IP, SHISA5
Alix is involved in caspase 9 activation during calcium-induced apoptosis.
Strappazzon F, Torch S, Chatellard-Causse C, Petiot A, Thibert C, Blot B, Verna JM, Sadoul R.
Biochem Biophys Res Commun 397(1):64-9. Epub 2010 May 21.PMID: 20471954 2010
7ALG2, PDCD6, PDCD6IP, TSG101
Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101.
Okumura M, Ichioka F, Kobayashi R, Suzuki H, Yoshida H, Shibata H, Maki M.
Biochem Biophys Res Commun 386(1):237-41. Epub 2009 Jun 9. 2009
8MCOLN1, PDCD6
Identification of the penta-EF-hand protein ALG-2 as a Ca2+-dependent interactor of mucolipin-1.
Vergarajauregui S, Martina JA, Puertollano R.
J Biol Chem 284(52):36357-66. Epub 2009 Oct 28.PMID: 19864416 2009
9ALG2, PDCD6, PDCD6IP
Alix and ALG-2 are involved in tumor necrosis factor receptor 1-induced cell death.
Mahul-Mellier AL, Strappazzon F, Petiot A, Chatellard-Causse C, Torch S, Blot B, Freeman K, Kuhn L, Garin J, Verna JM, Fraboulet S, Sadoul R.
J Biol Chem 283(50):34954-65. Epub 2008 Oct 20. 2008
10PDCD6, PDCD6IP
Structural basis for Ca2+ -dependent formation of ALG-2/Alix peptide complex: Ca2+/EF3-driven arginine switch mechanism.
Suzuki H, Kawasaki M, Inuzuka T, Okumura M, Kakiuchi T, Shibata H, Wakatsuki S, Maki M.
Structure 16(10):1562-73.PMID: 18940611 2008
11SEC31A, PDCD6, PDCD6IP
ALG-2 directly binds Sec31A and localizes at endoplasmic reticulum exit sites in a Ca2+-dependent manner.
Shibata H, Suzuki H, Yoshida H, Maki M.
Biochem Biophys Res Commun 353(3):756-63. Epub 2006 Dec 22. 2007
12PDCD6, SEC31A
The Ca2+-binding protein ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization of Sec31A.
Yamasaki A, Tani K, Yamamoto A, Kitamura N, Komada M.
Mol Biol Cell 17(11):4876-87. Epub 2006 Sep 6. 2006
13PDCD6, RBM22
Nuclear translocation of the calcium-binding protein ALG-2 induced by the RNA-binding protein RBM22.
Montaville P, Dai Y, Cheung CY, Giller K, Becker S, Michalak M, Webb SE, Miller AL, Krebs J.
Biochim Biophys Acta 1763(11):1335-43. Epub 2006 Sep 14. 2006
14PDCD6, PDCD6IP
Alix, a protein regulating endosomal trafficking, is involved in neuronal death.
Trioulier Y, Torch S, Blot B, Cristina N, Chatellard-Causse C, Verna JM, Sadoul R.
J Biol Chem 279(3):2046-52. Epub 2003 Oct 29. 2004
15PDCD6, ANXA11
The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent manner.
Satoh H, Nakano Y, Shibata H, Maki M.
Biochim Biophys Acta 1600(1-2):61-7. 2002
16PDCD6, PEF1
Peflin and ALG-2, members of the penta-EF-hand protein family, form a heterodimer that dissociates in a Ca2+-dependent manner.
Kitaura Y, Matsumoto S, Satoh H, Hitomi K, Maki M.
J Biol Chem 276(17):14053-8. 2001
17PDCD6
Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3.
Vito P, Lacana E, D'Adamio L.
Science 271(5248):521-5 1996