| 1 | PCSK5, SPP1
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| Osteopontin as a novel substrate for the proprotein convertase 5/6 (PCSK5) in bone.
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| Hoac B, Susan-Resiga D, Essalmani R, Marcinkiweicz E, Seidah NG, McKee MD.
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| Bone 107:45-55. doi: 10.1016/j.bone.2017.11.002. Epub 2017 Nov 7.
2018
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| 2 | PCSK5
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| Spatiotemporal expression of proprotein convertase subtilisin/kexin type 5 in the development of anorectal malformations in fetal rats.
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| Tang XB, Chen L, Wang WL, Yuan ZW, Bai YZ.
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| J Mol Histol 48(5-6):379-387. doi: 10.1007/s10735-017-9736-1. Epub 2017 Oct 3.
2017
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| 3 | PCSK5
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| Pcsk5 is required in the early cranio-cardiac mesoderm for heart development.
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| Szumska D, Cioroch M, Keeling A, Prat A, Seidah NG, Bhattacharya S.
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| BMC Dev Biol 17(1):6. doi: 10.1186/s12861-017-0148-y.
2017
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| 4 | PCSK5
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| PCSK5 mutation in a patient with the VACTERL association.
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| Nakamura Y, Kikugawa S, Seki S, Takahata M, Iwasaki N, Terai H, Matsubara M, Fujioka F, Inagaki H, Kobayashi T, Kimura T, Kurahashi H, Kato H.
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| BMC Res Notes 8:228. doi: 10.1186/s13104-015-1166-0.
2015
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| 5 | FURIN, PCSK5, PCSK6
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| Proprotein convertases in high-density lipoprotein metabolism.
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| Choi S, Korstanje R.
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| Biomark Res 1(1):27. doi: 10.1186/2050-7771-1-27.
2013
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| 6 | LTBP2, LTBP3, PCSK5
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| Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.
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| Sun X, Essalmani R, Susan-Resiga D, Prat A, Seidah NG.
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| J Biol Chem 286(33):29063-73. doi: 10.1074/jbc.M111.242479. Epub 2011 Jun 23.
2011
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| 7 | GDF11, PCSK5
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| PCSK5 and GDF11 expression in the hindgut region of mouse embryos with anorectal malformations.
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| Tsuda T, Iwai N, Deguchi E, Kimura O, Ono S, Furukawa T, Sasaki Y, Fumino S, Kubota Y.
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| Eur J Pediatr Surg 21(4):238-41. doi: 10.1055/s-0031-1273691. Epub 2011 Apr 8.
2011
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| 8 | ANGPTL3, LPL, PCSK5
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| Angiopoietin-like protein 3 inhibits lipoprotein lipase activity through enhancing its cleavage by proprotein convertases.
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| Liu J, Afroza H, Rader DJ, Jin W.
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| J Biol Chem 285(36):27561-70. Epub 2010 Jun 26. 2010
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| 9 | PCSK1, PCSK2, PCSK5, PCSK6
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| Subtilisin-like proprotein convertase expression, localization, and activity in the human retina and optic nerve head.
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| Fuller JA, Brun-Zinkernagel AM, Clark AF, Wordinger RJ.
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| Invest Ophthalmol Vis Sci 50(12):5759-68. Epub 2009 Apr 1. 2009
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| 10 | PCSK5
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| VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5.
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| Szumska D, Pieles G, Essalmani R, Bilski M, Mesnard D, Kaur K, Franklyn A, El Omari K, Jefferis J, Bentham J, Taylor JM, Schneider JE, Arnold SJ, Johnson P, Tymowska-Lalanne Z, Stammers D, Clarke K, Neubauer S, Morris A, Brown SD, Shaw-Smith C, Cama A, Capra V, Ragoussis J, Constam D, Seidah NG, Prat A, Bhattacharya S.
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| Genes Dev 22(11):1465-77.
2008
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| 11 | FURIN, PCSK1, PCSK2, PCSK5, PCSK6
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| PC1/3, PC2 and PC5/6A are targeted to dense core secretory granules by a common mechanism.
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| Dikeakos JD, Mercure C, Lacombe MJ, Seidah NG, Reudelhuber TL.
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| FEBS J 274(16):4094-102. Epub 2007 Jul 20.
2007
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| 12 | PCSK2, PCSK5
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| Inhibition of PC5 expression decreases CCK secretion and increases PC2 expression.
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| Reynolds NA, Blum A, Kitagawa K, Beinfeld MC.
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| Peptides 27(4):901-4. Epub 2005 Nov 2.
2006
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| 13 | PCSK5, PCSK6
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| The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases.
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| Nour N, Mayer G, Mort JS, Salvas A, Mbikay M, Morrison CJ, Overall CM, Seidah NG.
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| Mol Biol Cell 16(11):5215-26. Epub 2005 Aug 31.
2005
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| 14 | PCSK5
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| Single-nucleotide polymorphisms of the proprotein convertase subtilisin/ kexin type 5 (PCSK5) gene.
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| Cao H, Mok A, Miskie B, Hegele RA.
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| J Hum Genet 46(12):730-2. 2001
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| 15 | FURIN, PCSK6, PCSK1, PCSK2, PCSK4, PCSK5, PCSK7
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| A model for the structure of the P domains in the subtilisin-like prohormone convertases.
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| Lipkind GM, et al.
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| Proc Natl Acad Sci U S A 95(13):7310-5. 1998
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| 16 | PCSK5
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| Assignment of the human proprotein convertase gene PCSK5 to chromosome 9q21.3.
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| Van de Loo JWHP, et al.
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| Cytogenet Cell Genet 75 : 227-229. 1996
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| 17 | PCSK4, PCSK5, PCSK6
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| Chromosomal assignment of the genes for proprotein convertases PC4, PC5,and PACE 4 in mouse and human.
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| Mbikay M, et al.
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| Genomics 26 : 123-129. 1995
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| 18 | FURIN, PCSK6, PCSK1, PCSK2, PCSK4, PCSK5, PCSK7
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| The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.
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| Seidah NG, et al.
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| Biochimie 76(3-4):197-209. Review. 1994
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| 19 | FURIN, PCSK6, PCSK1, PCSK2, PCSK4, PCSK5, PCSK7
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| Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases.
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| Van de Ven WJ, et al.
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| Crit Rev Oncog 4(2):115-36. Review. 1993
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| 20 | PCSK1, PCSK2, FURIN, PCSK4, PCSK5, PCSK6
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| Mammalian subtilisins : the long-sought dibasic processing endoproteases.
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| Barr PJ.
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| Cell 66 : 1-3. 1991
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