Citations for
1PCSK5, SPP1
Osteopontin as a novel substrate for the proprotein convertase 5/6 (PCSK5) in bone.
Hoac B, Susan-Resiga D, Essalmani R, Marcinkiweicz E, Seidah NG, McKee MD.
Bone 107:45-55. doi: 10.1016/j.bone.2017.11.002. Epub 2017 Nov 7. 2018
2PCSK5
Spatiotemporal expression of proprotein convertase subtilisin/kexin type 5 in the development of anorectal malformations in fetal rats.
Tang XB, Chen L, Wang WL, Yuan ZW, Bai YZ.
J Mol Histol 48(5-6):379-387. doi: 10.1007/s10735-017-9736-1. Epub 2017 Oct 3. 2017
3PCSK5
Pcsk5 is required in the early cranio-cardiac mesoderm for heart development.
Szumska D, Cioroch M, Keeling A, Prat A, Seidah NG, Bhattacharya S.
BMC Dev Biol 17(1):6. doi: 10.1186/s12861-017-0148-y. 2017
4PCSK5
PCSK5 mutation in a patient with the VACTERL association.
Nakamura Y, Kikugawa S, Seki S, Takahata M, Iwasaki N, Terai H, Matsubara M, Fujioka F, Inagaki H, Kobayashi T, Kimura T, Kurahashi H, Kato H.
BMC Res Notes 8:228. doi: 10.1186/s13104-015-1166-0. 2015
5FURIN, PCSK5, PCSK6
Proprotein convertases in high-density lipoprotein metabolism.
Choi S, Korstanje R.
Biomark Res 1(1):27. doi: 10.1186/2050-7771-1-27. 2013
6LTBP2, LTBP3, PCSK5
Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.
Sun X, Essalmani R, Susan-Resiga D, Prat A, Seidah NG.
J Biol Chem 286(33):29063-73. doi: 10.1074/jbc.M111.242479. Epub 2011 Jun 23. 2011
7GDF11, PCSK5
PCSK5 and GDF11 expression in the hindgut region of mouse embryos with anorectal malformations.
Tsuda T, Iwai N, Deguchi E, Kimura O, Ono S, Furukawa T, Sasaki Y, Fumino S, Kubota Y.
Eur J Pediatr Surg 21(4):238-41. doi: 10.1055/s-0031-1273691. Epub 2011 Apr 8. 2011
8ANGPTL3, LPL, PCSK5
Angiopoietin-like protein 3 inhibits lipoprotein lipase activity through enhancing its cleavage by proprotein convertases.
Liu J, Afroza H, Rader DJ, Jin W.
J Biol Chem 285(36):27561-70. Epub 2010 Jun 26. 2010
9PCSK1, PCSK2, PCSK5, PCSK6
Subtilisin-like proprotein convertase expression, localization, and activity in the human retina and optic nerve head.
Fuller JA, Brun-Zinkernagel AM, Clark AF, Wordinger RJ.
Invest Ophthalmol Vis Sci 50(12):5759-68. Epub 2009 Apr 1. 2009
10PCSK5
VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5.
Szumska D, Pieles G, Essalmani R, Bilski M, Mesnard D, Kaur K, Franklyn A, El Omari K, Jefferis J, Bentham J, Taylor JM, Schneider JE, Arnold SJ, Johnson P, Tymowska-Lalanne Z, Stammers D, Clarke K, Neubauer S, Morris A, Brown SD, Shaw-Smith C, Cama A, Capra V, Ragoussis J, Constam D, Seidah NG, Prat A, Bhattacharya S.
Genes Dev 22(11):1465-77. 2008
11FURIN, PCSK1, PCSK2, PCSK5, PCSK6
PC1/3, PC2 and PC5/6A are targeted to dense core secretory granules by a common mechanism.
Dikeakos JD, Mercure C, Lacombe MJ, Seidah NG, Reudelhuber TL.
FEBS J 274(16):4094-102. Epub 2007 Jul 20. 2007
12PCSK2, PCSK5
Inhibition of PC5 expression decreases CCK secretion and increases PC2 expression.
Reynolds NA, Blum A, Kitagawa K, Beinfeld MC.
Peptides 27(4):901-4. Epub 2005 Nov 2. 2006
13PCSK5, PCSK6
The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases.
Nour N, Mayer G, Mort JS, Salvas A, Mbikay M, Morrison CJ, Overall CM, Seidah NG.
Mol Biol Cell 16(11):5215-26. Epub 2005 Aug 31. 2005
14PCSK5
Single-nucleotide polymorphisms of the proprotein convertase subtilisin/ kexin type 5 (PCSK5) gene.
Cao H, Mok A, Miskie B, Hegele RA.
J Hum Genet 46(12):730-2. 2001
15FURIN, PCSK6, PCSK1, PCSK2, PCSK4, PCSK5, PCSK7
A model for the structure of the P domains in the subtilisin-like prohormone convertases.
Lipkind GM, et al.
Proc Natl Acad Sci U S A 95(13):7310-5. 1998
16PCSK5
Assignment of the human proprotein convertase gene PCSK5 to chromosome 9q21.3.
Van de Loo JWHP, et al.
Cytogenet Cell Genet 75 : 227-229. 1996
17PCSK4, PCSK5, PCSK6
Chromosomal assignment of the genes for proprotein convertases PC4, PC5,and PACE 4 in mouse and human.
Mbikay M, et al.
Genomics 26 : 123-129. 1995
18FURIN, PCSK6, PCSK1, PCSK2, PCSK4, PCSK5, PCSK7
The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.
Seidah NG, et al.
Biochimie 76(3-4):197-209. Review. 1994
19FURIN, PCSK6, PCSK1, PCSK2, PCSK4, PCSK5, PCSK7
Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases.
Van de Ven WJ, et al.
Crit Rev Oncog 4(2):115-36. Review. 1993
20PCSK1, PCSK2, FURIN, PCSK4, PCSK5, PCSK6
Mammalian subtilisins : the long-sought dibasic processing endoproteases.
Barr PJ.
Cell 66 : 1-3. 1991