| 1 | CFNCS, PCGF2
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| Missense Mutations of the Pro65 Residue of PCGF2 Cause a Recognizable Syndrome Associated with Craniofacial, Neurological, Cardiovascular, and Skeletal Features.
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| Turnpenny PD, Wright MJ, Sloman M, Caswell R, van Essen AJ, Gerkes E, Pfundt R, White SM, Shaul-Lotan N, Carpenter L, Schaefer GB, Fryer A, Innes AM, Forbes KP, Chung WK, McLaughlin H, Henderson LB, Roberts AE, Heath KE, Paumard-Hernández B, Gener B; DDD study, Fawcett KA, Gjergja-Juraški R, Pilz DT, Fry AE.
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| Am J Hum Genet 103(5):786-793. doi: 10.1016/j.ajhg.2018.09.012. Epub 2018 Oct 18.
2018
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| 2 | BMI1, PCGF2
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| Multiple polycomb epigenetic regulatory proteins are active in normal and regenerating adult olfactory epithelium.
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| Goldstein BJ, Choi R, Goss GM.
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| Laryngoscope Investig Otolaryngol 3(5):337-344. doi: 10.1002/lio2.180. eCollection 2018 Oct.
2018
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| 3 | PCGF2
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| MEL-18 loss mediates estrogen receptor-α downregulation and hormone independence.
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| Lee JY, Won HY, Park JH, Kim HY, Choi HJ, Shin DH, Kang JH, Woo JK, Oh SH, Son T, Choi JW, Kim S, Kim HY, Yi K, Jang KS, Oh YH, Kong G.
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| J Clin Invest 125(5):1801-14. doi: 10.1172/JCI73743. Epub 2015 Mar 30.
2015
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| 4 | PCGF2
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| Expression and clinicopathological significance of Mel-18 mRNA in colorectal cancer.
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| Tao J, Liu YL, Zhang G, Ma YY, Cui BB, Yang YM.
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| Tumour Biol 35(10):9619-25. doi: 10.1007/s13277-014-2220-6. Epub 2014 Jun 27.
2014
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| 5 | PCGF2
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| Loss of Mel-18 enhances breast cancer stem cell activity and tumorigenicity through activating Notch signaling mediated by the Wnt/TCF pathway.
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| Won HY, Lee JY, Shin DH, Park JH, Nam JS, Kim HC, Kong G.
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| FASEB J 26(12):5002-13. doi: 10.1096/fj.12-209247. Epub 2012 Sep 5.
2012
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| 6 | BMI1, PCGF2
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| Regulation of hematopoietic stem cells using protein transduction domain-fused Polycomb.
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| Kajiume T, Sera Y, Kawahara Y, Matsumoto M, Fukazawa T, Imura T, Yuge L, Kobayashi M.
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| Exp Hematol 40(9):751-760.e1. doi: 10.1016/j.exphem.2012.05.005. Epub 2012 May 24.
2012
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| 7 | PCGF2
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| Loss of Mel-18 induces tumor angiogenesis through enhancing the activity and expression of HIF-1α mediated by the PTEN/PI3K/Akt pathway.
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| Park JH, Lee JY, Shin DH, Jang KS, Kim HJ, Kong G.
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| Oncogene 30(45):4578-89. doi: 10.1038/onc.2011.174. Epub 2011 May 23.
2011
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| 8 | PCGF2
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| Inhibition of PCGF2 enhances granulocytic differentiation of acute promyelocytic leukemia cell line HL-60 via induction of HOXA7.
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| Jo S, Lee H, Kim S, Hwang EM, Park JY, Kang SS, Chung H.
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| Biochem Biophys Res Commun 416(1-2):86-91. doi: 10.1016/j.bbrc.2011.10.152. Epub 2011 Nov 9.
2011
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| 9 | BMI1, PCGF2
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| BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer.
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| Zhang XW, Sheng YP, Li Q, Qin W, Lu YW, Cheng YF, Liu BY, Zhang FC, Li J, Dimri GP, Guo WJ.
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| Mol Cancer 9:40.
2010
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| 10 | PCGF2
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| Mel-18, a mammalian Polycomb gene, regulates angiogenic gene expression of endothelial cells.
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| Jung JH, Choi HJ, Maeng YS, Choi JY, Kim M, Kwon JY, Park YW, Kim YM, Hwang D, Kwon YG.
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| Biochem Biophys Res Commun 400(4):523-30. Epub 2010 Aug 27.
2010
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| 11 | PCGF2
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| The novel tumor-suppressor Mel-18 in prostate cancer: its functional polymorphism, expression and clinical significance.
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| Wang W, Yuasa T, Tsuchiya N, Ma Z, Maita S, Narita S, Kumazawa T, Inoue T, Tsuruta H, Horikawa Y, Saito M, Hu W, Ogawa O, Habuchi T.
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| Int J Cancer 125(12):2836-43. doi: 10.1002/ijc.24721.
2009
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| 12 | HSF2, PCGF2, RANGAP1
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| Mel-18 interacts with RanGAP1 and inhibits its sumoylation.
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| Zhang J, Sarge KD.
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| Biochem Biophys Res Commun 375(2):252-5. Epub 2008 Aug 14.
2008
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| 13 | PCGF2, RANGAP1
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| Mel-18 interacts with RanGAP1 and inhibits its sumoylation.
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| Zhang J, Sarge KD.
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| Biochem Biophys Res Commun 375(2):252-5. doi: 10.1016/j.bbrc.2008.08.012. Epub 2008 Aug 14.
2008
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| 14 | BMI1, MYC, PCGF2
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| Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins.
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| Guo WJ, Datta S, Band V, Dimri GP.
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| Mol Biol Cell 18(2):536-46. Epub 2006 Dec 6.
2007
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| 15 | PCGF2
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| Dimerization of the Polycomb-group protein Mel-18 is regulated by PKC phosphorylation.
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| Fujisaki S, Ninomiya Y, Ishihara H, Miyazaki M, Kanno R, Asahara T, Kanno M.
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| Biochem Biophys Res Commun 300(1):135-40.
2003
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| 16 | PCGF2
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| Chemokine-mediated thymopoiesis is regulated by a mammalian Polycomb group gene, mel-18.
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| Miyazaki K, Inoue H, Onai N, Ishihara H, Kanno M.
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| Immunol Lett 80(2):139-43. 2002
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| 17 | PCGF2
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| Mutation analysis of the mel-18 gene that shows decreased expression in human breast cancer cell lines.
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| Matsuo F, Yano K, Saito H, Morotomi K, Kato M, Yoshimoto M, Kasumi F, Akiyama F, Sakamoto G, Miki Y.
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| Breast Cancer 9(1):33-8. 2002
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| 18 | PCGF2
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| Cloning and chromosome mapping of the human Mel-18 gene which encodes a DNA-binding protein with a new 'RING-finger' motif.
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| Ishida A, Asano H, Hasegawa M, Koseki H, Ono T, Yoshida MC, Taniguchi M,Kanno M.
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| Gene 129(2):249-55. 1993
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