| 1 | GADD45G, PAX5
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| Paired box 5 is a frequently methylated lung cancer tumour suppressor gene interfering β-catenin signalling and GADD45G expression.
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| Zhao L, Li S, Gan L, Li C, Qiu Z, Feng Y, Li J, Li L, Li C, Peng W, Xu C, Wang Z, Hui T, Ren G, Tao Q, Xiang T.
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| J Cell Mol Med 20(5):842-54. doi: 10.1111/jcmm.12768. Epub 2016 Feb 4.
2016
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| 2 | MCOLN2, PAX5
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| PAX5 is the transcriptional activator of mucolipin-2 (MCOLN2) gene.
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| Valadez JA, Cuajungco MP.
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| Gene 555(2):194-202. doi: 10.1016/j.gene.2014.11.003. Epub 2014 Nov 6.
2015
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| 3 | PAX5
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| Alternative splicing of the trout Pax5 gene and identification of novel B cell populations using Pax5 signatures.
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| Macmurray E, Barr M, Bruce A, Epp L, Zwollo P.
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| Dev Comp Immunol 41(2):270-81. doi: 10.1016/j.dci.2013.06.008. Epub 2013 Jun 21.
2013
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| 4 | PAX5, SOX11
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| SOX11 regulates PAX5 expression and blocks terminal B-cell differentiation in aggressive mantle cell lymphoma.
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| Vegliante MC, Palomero J, Pérez-Galán P, Roué G, Castellano G, Navarro A, Clot G, Moros A, Suárez-Cisneros H, Beŕ S, Hernández L, Enjuanes A, Jares P, Villamor N, Colomer D, Martín-Subero JI, Campo E, Amador V.
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| Blood 121(12):2175-85. doi: 10.1182/blood-2012-06-438937. Epub 2013 Jan 15.
2013
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| 5 | AICDA, PAX5
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| Activation of Aicda gene transcription by Pax5 in plasmacytoma cells.
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| Dege C, Hagman J.
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| Immunol Res 55(1-3):155-61. doi: 10.1007/s12026-012-8357-8.
2013
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| 6 | EBF1, PAX5
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| Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells.
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| Nechanitzky R, Akbas D, Scherer S, Györy I, Hoyler T, Ramamoorthy S, Diefenbach A, Grosschedl R.
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| Nat Immunol 14(8):867-75. doi: 10.1038/ni.2641. Epub 2013 Jun 30.
2013
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| 7 | PAX5
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| Germline PAX5 mutations and B cell leukemia.
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| Hyde RK, Liu PP.
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| Nat Genet 45(10):1104-5. doi: 10.1038/ng.2778.
2013
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| 8 | PAX5
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| A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia.
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| Shah S, Schrader KA, Waanders E, Timms AE, Vijai J, Miething C, Wechsler J, Yang J, Hayes J, Klein RJ, Zhang J, Wei L, Wu G, Rusch M, Nagahawatte P, Ma J, Chen SC, Song G, Cheng J, Meyers P, Bhojwani D, Jhanwar S, Maslak P, Fleisher M, Littman J, Offit L, Rau-Murthy R, Fleischut MH, Corines M, Murali R, Gao X, Manschreck C, Kitzing T, Murty VV, Raimondi SC, Kuiper RP, Simons A, Schiffman JD, Onel K, Plon SE, Wheeler DA, Ritter D, Ziegler DS, Tucker K, Sutton R, Chenevix-Trench G, Li J, Huntsman DG, Hansford S, Senz J, Walsh T, Lee M, Hahn CN, Roberts KG, King MC, Lo SM, Levine RL, Viale A, Socci ND, Nathanson KL, Scott HS, Daly M, Lipkin SM, Lowe SW, Downing JR, Altshuler D, Sandlund JT, Horwitz MS, Mullighan CG, Offit K.
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| Nat Genet 45(10):1226-31. doi: 10.1038/ng.2754. Epub 2013 Sep 8.
2013
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| 9 | PAX5
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| The transcription factor paired box-5 promotes osteoblastogenesis through direct induction of Osterix and Osteocalcin.
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| Hinoi E, Nakatani E, Yamamoto T, Iezaki T, Takahata Y, Fujita H, Ishiura R, Takamori M, Yoneda Y.
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| J Bone Miner Res 27(12):2526-34. doi: 10.1002/jbmr.1708.
2012
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| 10 | PAX5
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| The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis.
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| Revilla-I-Domingo R, Bilic I, Vilagos B, Tagoh H, Ebert A, Tamir IM, Smeenk L, Trupke J, Sommer A, Jaritz M, Busslinger M.
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| EMBO J 31(14):3130-46. doi: 10.1038/emboj.2012.155.
2012
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| 11 | AUTS2, PAX5
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| PAX5-AUTS2: a recurrent fusion gene in childhood B-cell precursor acute lymphoblastic leukemia.
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| Denk D, Nebral K, Bradtke J, Pass G, Möricke A, Attarbaschi A, Strehl S.
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| Leuk Res 36(8):e178-81. doi: 10.1016/j.leukres.2012.04.015. Epub 2012 May 12. Review.
2012
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| 12 | PAX5
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| PAX5-PML acts as a dual dominant-negative form of both PAX5 and PML.
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| Kurahashi S, Hayakawa F, Miyata Y, Yasuda T, Minami Y, Tsuzuki S, Abe A, Naoe T.
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| Oncogene 30(15):1822-30. Epub 2011 Jan 10.
2011
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| 13 | FOXP1, PAX5
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| FOXP1 and PAX5 are rare but recurrent translocations partners in acute lymphoblastic leukemia.
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| Put N, Deeren D, Michaux L, Vandenberghe P.
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| Cancer Genet 204(8):462-4.
2011
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| 14 | PAX5
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| The Pax-5 gene: a pluripotent regulator of B-cell differentiation and cancer disease.
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| O'Brien P, Morin P Jr, Ouellette RJ, Robichaud GA.
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| Cancer Res 71(24):7345-50. doi: 10.1158/0008-5472.CAN-11-1874. Epub 2011 Nov 29. Review.
2011
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| 15 | PAX5
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| The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells.
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| McManus S, Ebert A, Salvagiotto G, Medvedovic J, Sun Q, Tamir I, Jaritz M, Tagoh H, Busslinger M.
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| EMBO J 30(12):2388-404. doi: 10.1038/emboj.2011.140.
2011
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| 16 | EP300, PAX5
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| Histone acetyltransferase p300 acetylates Pax5 and strongly enhances Pax5-mediated transcriptional activity.
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| He T, Hong SY, Huang L, Xue W, Yu Z, Kwon H, Kirk M, Ding SJ, Su K, Zhang Z.
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| J Biol Chem 286(16):14137-45. doi: 10.1074/jbc.M110.176289. Epub 2011 Feb 25.
2011
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| 17 | PAAXIP1, PAX5
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| Role of PTIP in class switch recombination and long-range chromatin interactions at the immunoglobulin heavy chain locus.
|
| Schwab KR, Patel SR, Dressler GR.
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| Mol Cell Biol 31(7):1503-11. doi: 10.1128/MCB.00990-10. Epub 2011 Jan 31.
2011
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| 18 | CD19, PAX5
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| Aberrant expression of CD19 in AML with t(8;21) involves a poised chromatin structure and PAX5.
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| Walter K, Cockerill PN, Barlow R, Clarke D, Hoogenkamp M, Follows GA, Richards SJ, Cullen MJ, Bonifer C, Tagoh H.
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| Oncogene 29(20):2927-37. Epub 2010 Mar 8.PMID: 20208555 2010
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| 19 | PAX5
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| Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia.
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| Nebral K, Denk D, Attarbaschi A, König M, Mann G, Haas OA, Strehl S.
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| Leukemia 23(1):134-43. Epub 2008 Nov 20.
2009
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| 20 | ASXL1, PAX5
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| Heterogeneous breakpoints in patients with acute lymphoblastic leukemia and the dic(9;20)(p11-13;q11) show recurrent involvement of genes at 20q11.21.
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| An Q, Wright SL, Moorman AV, Parker H, Griffiths M, Ross FM, Davies T, Harrison CJ, Strefford JC.
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| Haematologica 94(8):1164-9. Epub 2009 Jul 7.PMID: 19586940 2009
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| 21 | PAX5
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| PAX-5 is invariably expressed in B-cell lymphomas without plasma cell differentiation.
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| Dong HY, Browne P, Liu Z, Gangi M.
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| Histopathology 53(3):278-87. Epub 2008 Jul 16.
2008
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| 22 | ATP9A, PAX5
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| Variable breakpoints target PAX5 in patients with dicentric chromosomes: a model for the basis of unbalanced translocations in cancer.
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| An Q, Wright SL, Konn ZJ, Matheson E, Minto L, Moorman AV, Parker H, Griffiths M, Ross FM, Davies T, Hall AG, Harrison CJ, Irving JA, Strefford JC.
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| Proc Natl Acad Sci U S A 105(44):17050-4. doi: 10.1073/pnas.0803494105. Epub 2008 Oct 28.
2008
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| 23 | EBF1,IKZF1,IKZF3,LEF1,PAX5,TCF3
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| Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.
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| Mullighan CG, Goorha S, Radtke I, Miller CB, Coustan-Smith E, Dalton JD, Girtman K, Mathew S, Ma J, Pounds SB, Su X, Pui CH, Relling MV, Evans WE, Shurtleff SA, Downing JR.
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| Nature 446(7137):758-64. 2007
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| 24 | MYC, PAX5, ZBTB5, ZCCHC7
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| Mapping of MYC breakpoints in 8q24 rearrangements involving non-immunoglobulin partners in B-cell lymphomas.
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| Bertrand P, Bastard C, Maingonnat C, Jardin F, Maisonneuve C, Courel MN, Ruminy P, Picquenot JM, Tilly H.
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| Leukemia 21(3):515-23. Epub 2007 Jan 18.
2007
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| 25 | ELN, PAX5
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| A novel PAX5-ELN fusion protein identified in B-cell acute lymphoblastic leukemia acts as a dominant negative on wild-type PAX5.
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| Bousquet M, Broccardo C, Quelen C, Meggetto F, Kuhlein E, Delsol G, Dastugue N, Brousset P.
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| Blood 109(8):3417-23. Epub 2006 Dec 19.
2007
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| 26 | ETV6, FOXP1, PAX5, PML, ZNF521
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| Identification of PML as novel PAX5 fusion partner in childhood acute lymphoblastic leukaemia.
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| Nebral K, König M, Harder L, Siebert R, Haas OA, Strehl S.
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| Br J Haematol 139(2):269-74. 2007
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| 27 | PAX5, IGH
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| PAX5/IGH rearrangement is a recurrent finding in a subset of aggressive B-NHL with complex chromosomal rearrangements.
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| Poppe B, De Paepe P, Michaux L, Dastugue N, Bastard C, Herens C, Moreau E, Cavazzini F, Yigit N, Van Limbergen H, De Paepe A, Praet M, De Wolf-Peeters C, Wlodarska I, Speleman F.
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| Genes Chromosomes Cancer 44(2):218-23. 2005
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| 28 | PAX5, ETV6
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| PAX5/ETV6 fusion defines cytogenetic entity dic(9;12)(p13;p13).
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| Strehl S, Konig M, Dworzak MN, Kalwak K, Haas OA.
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| Leukemia 17(6):1121-3. 2003
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| 29 | PAX5
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| Reversion of B cell commitment upon loss of Pax5 expression.
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| Mikkola I, Heavey B, Horcher M, Busslinger M.
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| Science 297(5578):110-3. 2002
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| 30 | DAXX, PAX5
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| The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells.
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| Emelyanov AV, Kovac CR, Sepulveda MA, Birshtein BK.
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| J Biol Chem 277(13):11156-64. 2002
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| 31 | CCND1, PAX5, TAL1
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| Proteins encoded by genes involved in chromosomal alterations in lymphoma and leukemia: clinical value of their detection by immunocytochemistry.
|
| Falini B, Mason DY.
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| Blood 99(2):409-26. Review. 2002
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| 32 | CCIN, CLTA, CREB3, GNE, IBM2, MELK, PAX5, RECK
|
| Physical and transcriptional map of the hereditary inclusion body myopathy locus on chromosome 9p12-p13.
|
| Eisenberg I, Hochner H, Shemesh M, Levi T, Potikha T, Sadeh M, Argov Z, Jackson CL, Mitrani-Rosenbaum S.
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| Eur J Hum Genet 9(7):501-9. 2001
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| 33 | PAX5
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| The paired box domain gene PAX5 is fused to ETV6/TEL in an acute lymphoblastic leukemia case.
|
| Cazzaniga G, Daniotti M, Tosi S, Giudici G, Aloisi A, Pogliani E, Kearney L, Biondi A.
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| Cancer Res 61(12):4666-70. 2001
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| 34 | KPNA2, PAX5
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| BSAP (Pax5)-importin alpha 1 (Rch1) interaction identifies a nuclear localization sequence.
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| Kovac CR, Emelyanov A, Singh M, Ashouian N, Birshtein BK.
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| J Biol Chem 275(22):16752-7. 2000
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| 35 | PAX5
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| Independent regulation of the two Pax5 alleles during B-cell development.
|
| Nutt SL, et al.
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| Nat Genet 21(4):390-5. 1999
|
| 36 | PAX5
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| Chromosomal rearrangement of the PAX-5 locus in lymphoplasmacytic lymphoma with t(9;14)(p13;q32).
|
| Iida S, et al.
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| Leuk Lymphoma 34(1-2):25-33. Review. 1999
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| 37 | PAX5
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| Monoallelic expression of Pax5: a paradigm for the haploinsufficiency of mammalian Pax genes?
|
| Nutt SL, et al.
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| Biol Chem 380(6):601-11. Review 1999
|
| 38 | ETS1, PAX2, PAX3, PAX5
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| The highly conserved beta-hairpin of the paired DNA-binding domain is required for assembly of Pax-Ets ternary complexes.
|
| Wheat W, Fitzsimmons D, Lennox H, Krautkramer SR, Gentile LN, McIntosh LP, Hagman J.
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| Mol Cell Biol 19(3):2231-41. 1999
|
| 39 | CD19, PAX5
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| Identification of BSAP (pax-5) target genes in early B-cell development by loss-and gain-of-function experiments.
|
| Nutt SL, et al.
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| EMBO J 17 : 2319-2333. 1998
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| 40 | PAX5
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| Deregulated PAX-5 transcription from a translocated IgH promoter in marginal zone lymphoma.
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| Morrison AM, Jager U, Chott A, Schebesta M, Haas OA, Busslinger M.
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| Blood 92 : 3865-3878. 1998
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| 41 | PAX5, KIS1
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| Deregulation of PAX-5 by translocation of the E mu enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphoma.
|
| Busslinger M, et al.
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| Proc Natl Acad Sci U S A 93 : 6129-6134. 1996
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| 42 | KIS1, PAX5
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| The t(9;14)(p13;q32) chromosomal translocation associated with lymphoplasmacytoid lymphoma involves the PAX-5 gene.
|
| Iida S, et al.
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| Blood 88 : 4110-4117. 1996
|
| 43 | PAX5
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| The PAX5 gene : a linkage and mutation analysis in candidate human primary immunodeficiencies.
|
| Vorechovsky I, et al.
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| Immunogenetics 42 : 149-152. 1995
|
| 44 | PAX5
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| An intragenic Taql RFLP at the PAX5 locus.
|
| Vorechovsky I, et al.
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| Hum Mol Genet 3 : 681. 1994
|
| 45 | PAX5
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| SSCP/Sacl polymorphism in the PAX5 gene.
|
| Vorechovsky I, et al.
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| Hum Mol Genet 3 : 839. 1994
|
| 46 | PAX2, PAX4, PAX5, PAX7, PAX8, PAX9
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| Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9.
|
| Stapleton P, et al.
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| Nat Genet 3 : 292-298. 1993
|
| 47 | PAX5
|
| Mapping of the human homologs of the murine paired-box-containing genes.
|
| Pilz AJ, Povey S, Gruss P, Abbott CM.
|
| Mamm Genome 4(2):78-82.
1993
|
| 48 | PAX5
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| Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.
|
| Adams B, et al.
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| Genes Dev 6 : 1589-1607. 1992
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| 49 | PAX5
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| A novel B-cell lineage-specific transcription factor present at early but not late stages of differentiation.
|
| Barberis A, et al.
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| Genes Dev 4 : 849-859. 1990
|
| 50 | PAX5, KIS1
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| Molecular analysis of a chromosomal translocation, t(9;14)(p13;q32), in a diffuse large-cell lymphoma cell line expressing the Ki-1 antigen.
|
| Ohno H, et al.
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| Proc Natl Acad Sci U S A 87 : 628-632. 1990
|