| 1 | PARP1, TIMELESS, TIPIN
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| Transcription-replication conflicts underlie sensitivity to PARP inhibitors
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| Petropoulos M, Karamichali A, Rossetti GG, Freudenmann A, Iacovino LG, Dionellis VS, Sotiriou SK, Halazonetis TD.
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| Nature. Apr;628(8007):433-441. doi: 10.1038/s41586-024-07217-2. Epub 2024 Mar 20. 2024
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| 2 | IRF1, PARP1
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| Inhibition of PARP1 Increases IRF-dependent Gene Transcription in Jurkat Cells.
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| Wang C, Du M, Huang D, Huang K, Huang K.
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| Curr Med Sci 39(3):356-362. doi: 10.1007/s11596-019-2043-1. Epub 2019 Jun 17.
2019
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| 3 | PARP1, SEPTIN4
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| Septin4 as a novel binding partner of PARP1 contributes to oxidative stress induced human umbilical vein endothelial cells injure.
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| Zhang N, Zhang Y, Zhao S, Sun Y.
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| Biochem Biophys Res Commun 496(2):621-627. doi: 10.1016/j.bbrc.2018.01.105.
2018
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| 4 | DDB2, PARP1, XPC
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| Poly(ADP-ribose) polymerase 1 escorts XPC to UV-induced DNA lesions during nucleotide excision repair.
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| Robu M, Shah RG, Purohit NK, Zhou P, Naegeli H, Shah GM.
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| Proc Natl Acad Sci U S A 114(33):E6847-E6856. doi: 10.1073/pnas.1706981114. Epub 2017 Jul 31.
2017
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| 5 | PARP1, PARP2, PNKP, XRCC1
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| Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin.
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| Hanzlikova H, Gittens W, Krejcikova K, Zeng Z, Caldecott KW.
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| Nucleic Acids Res 45(5):2546-2557. doi: 10.1093/nar/gkw1246.
2017
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| 6 | CASP1, NOS2, PARP1
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| Epigenetic regulation of nitric oxide synthase 2, inducible (Nos2) by NLRC4 inflammasomes involves PARP1 cleavage.
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| Buzzo CL, Medina T, Branco LM, Lage SL, Ferreira LC, Amarante-Mendes GP, Hottiger MO, De Carvalho DD, Bortoluci KR.
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| Sci Rep 7:41686. doi: 10.1038/srep41686.
2017
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| 7 | BLM, PARP1, RECQL, RECQL4, RECQL5, WRN
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| RecQ helicases and PARP1 team up in maintaining genome integrity.
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| Veith S, Mangerich A.
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| Ageing Res Rev 23(Pt A):12-28. doi: 10.1016/j.arr.2014.12.006. Epub 2014 Dec 30. Review.
2015
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| 8 | PARP1
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| Poly(ADP-ribose)polymerase 1 stimulates the AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1.
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| Lebedeva NA, Anarbaev RO, Sukhanova M, Vasil'eva IA, Rechkunova NI, Lavrik OI.
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| Biosci Rep 35(4). pii: e00230. doi: 10.1042/BSR20140192.
2015
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| 9 | PARP1, RECQL5, WRN
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| Differential and Concordant Roles for Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribose) in Regulating WRN and RECQL5 Activities.
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| Khadka P, Hsu JK, Veith S, Tadokoro T, Shamanna RA, Mangerich A, Croteau DL, Bohr VA.
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| Mol Cell Biol 35(23):3974-89. doi: 10.1128/MCB.00427-15. Epub 2015 Sep 21.
2015
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| 10 | PARP1, TIMELESS, TIPIN
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| TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage Response.
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| Young LM, Marzio A, Perez-Duran P, Reid DA, Meredith DN, Roberti D, Star A, Rothenberg E, Ueberheide B, Pagano M.
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| Cell Rep. Oct 20;13(3):451-459. doi: 10.1016/j.celrep.2015.09.017. Epub 2015 Oct 8. 2015
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| 11 | PARP1, UHRF1
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| Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitine-protein ligase UHRF1 and modulates UHRF1 biological functions.
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| De Vos M, El Ramy R, Quénet D, Wolf P, Spada F, Magroun N, Babbio F, Schreiber V, Leonhardt H, Bonapace IM, Dantzer F.
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| J Biol Chem Biol Chem. 2014 Apr 29. [Epub ahead of print]
2014
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| 12 | FOXP3, PARP1
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| PARP-1 controls immunosuppressive function of regulatory T cells by destabilizing Foxp3.
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| Zhang P, Maruyama T, Konkel JE, Abbatiello B, Zamarron B, Wang ZQ, Chen W.
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| PLoS One 8(8):e71590. doi: 10.1371/journal.pone.0071590. eCollection 2013.
2013
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| 13 | PARP1
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| PARP1 represses PAP and inhibits polyadenylation during heat shock.
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| Di Giammartino DC, Shi Y, Manley JL.
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| Mol Cell 49(1):7-17. doi: 10.1016/j.molcel.2012.11.005. Epub 2012 Dec 6.
2013
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| 14 | BCL6, PARP1, PRKAA2
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| AMPKα2 exerts its anti-inflammatory effects through PARP-1 and Bcl-6.
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| Gongol B, Marin T, Peng IC, Woo B, Martin M, King S, Sun W, Johnson DA, Chien S, Shyy JY.
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| Proc Natl Acad Sci U S A 110(8):3161-6. doi: 10.1073/pnas.1222051110. Epub 2013 Feb 4.
2013
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| 15 | ETS1, PARP1
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| The level of Ets-1 protein is regulated by poly(ADP-ribose) polymerase-1 (PARP-1) in cancer cells to prevent DNA damage.
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| Legrand AJ, Choul-Li S, Spriet C, Idziorek T, Vicogne D, Drobecq H, Dantzer F, Villeret V, Aumercier M.
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| PLoS One 8(2):e55883. doi: 10.1371/journal.pone.0055883. Epub 2013 Feb 6.
2013
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| 16 | PARP1, RECQL
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| Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition.
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| Berti M, Ray Chaudhuri A, Thangavel S, Gomathinayagam S, Kenig S, Vujanovic M, Odreman F, Glatter T, Graziano S, Mendoza-Maldonado R, Marino F, Lucic B, Biasin V, Gstaiger M, Aebersold R, Sidorova JM, Monnat RJ Jr, Lopes M, Vindigni A.
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| Nat Struct Mol Biol 20(3):347-54. doi: 10.1038/nsmb.2501. Epub 2013 Feb 10.
2013
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| 17 | PARP1, TET2
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| Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2.
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| Doege CA, Inoue K, Yamashita T, Rhee DB, Travis S, Fujita R, Guarnieri P, Bhagat G, Vanti WB, Shih A, Levine RL, Nik S, Chen EI, Abeliovich A.
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| Nature 488(7413):652-5. doi: 10.1038/nature11333.
2012
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| 18 | PARP1, PARP2
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| Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors.
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| Murai J, Huang SY, Das BB, Renaud A, Zhang Y, Doroshow JH, Ji J, Takeda S, Pommier Y.
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| Cancer Res 72(21):5588-99. doi: 10.1158/0008-5472.CAN-12-2753.
2012
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| 19 | PARP1, PARP2
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| The role of PARP-1 and PARP-2 enzymes in metabolic regulation and disease.
|
| Bai P, Cantó C.
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| Cell Metab 16(3):290-5. doi: 10.1016/j.cmet.2012.06.016. Epub 2012 Aug 23. Review.
2012
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| 20 | PARP1, PARP2
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| Cell death and autophagy under oxidative stress: roles of poly(ADP-Ribose) polymerases and Ca(2+).
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| Wyrsch P, Blenn C, Bader J, Althaus FR.
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| Mol Cell Biol 32(17):3541-53. doi: 10.1128/MCB.00437-12. Epub 2012 Jul 2.
2012
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| 21 | PARP1, SOX2
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| SRY (sex determining region Y)-box2 (Sox2)/poly ADP-ribose polymerase 1 (Parp1) complexes regulate pluripotency.
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| Lai YS, Chang CW, Pawlik KM, Zhou D, Renfrow MB, Townes TM.
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| Proc Natl Acad Sci U S A 109(10):3772-7. doi: 10.1073/pnas.1108595109. Epub 2012 Feb 23.
2012
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| 22 | NEIL1, PARP1
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| Coordination of DNA repair by NEIL1 and PARP-1: a possible link to aging.
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| Noren Hooten N, Fitzpatrick M, Kompaniez K, Jacob KD, Moore BR, Nagle J, Barnes J, Lohani A, Evans MK.
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| Aging (Albany NY) 4(10):674-85.
2012
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| 23 | CHFR, PARP1
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| CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation.
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| Kashima L, Idogawa M, Mita H, Shitashige M, Yamada T, Ogi K, Suzuki H, Toyota M, Ariga H, Sasaki Y, Tokino T.
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| J Biol Chem 287(16):12975-84. doi: 10.1074/jbc.M111.321828. Epub 2012 Feb 15.
2012
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| 24 | BAZ2A, PARP1
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| Inheritance of silent rDNA chromatin is mediated by PARP1 via noncoding RNA.
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| Guetg C, Scheifele F, Rosenthal F, Hottiger MO, Santoro R.
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| Mol Cell 45(6):790-800. doi: 10.1016/j.molcel.2012.01.024. Epub 2012 Mar 8.
2012
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| 25 | PARP1
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| Increased transcript level of poly(ADP-ribose) polymerase (PARP-1) in human tricuspid compared with bicuspid aortic valves correlates with the stenosis severity.
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| Nagy E, Caidahl K, Franco-Cereceda A, Bäck M.
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| Biochem Biophys Res Commun 420(3):671-5. doi: 10.1016/j.bbrc.2012.03.064. Epub 2012 Mar 17.
2012
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| 26 | PARP1
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| Increased transcript level of poly(ADP-ribose) polymerase (PARP-1) in human tricuspid compared with bicuspid aortic valves correlates with the stenosis severity.
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| Nagy E, Caidahl K, Franco-Cereceda A, Bäck M.
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| Biochem Biophys Res Commun 420(3):671-5. doi: 10.1016/j.bbrc.2012.03.064. Epub 2012 Mar 17.
2012
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| 27 | HOXB7, PARP1
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| ADP ribosylation by PARP-1 suppresses HOXB7 transcriptional activity.
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| Wu X, Ellmann S, Rubin E, Gil M, Jin K, Han L, Chen H, Kwon EM, Guo J, Ha HC, Sukumar S.
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| PLoS One 7(7):e40644. doi: 10.1371/journal.pone.0040644. Epub 2012 Jul 23.
2012
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| 28 | PARP1, SH3BP2
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| Cloning and characterization of the human SH3BP2 promoter.
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| Fan C, Gaivin RJ, Marth TA, Willard B, Levine MA, Lietman SA.
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| Biochem Biophys Res Commun 425(1):25-32. doi: 10.1016/j.bbrc.2012.07.043. Epub 2012 Jul 17.
2012
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| 29 | PARP1
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| Structural basis for DNA damage-dependent poly(ADP-ribosyl)ation by human PARP-1.
|
| Langelier MF, Planck JL, Roy S, Pascal JM.
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| Science 336(6082):728-32. doi: 10.1126/science.1216338.
2012
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| 30 | HMGN1, PARP1
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| HMGN1 protein regulates poly(ADP-ribose) polymerase-1 (PARP-1) self-PARylation in mouse fibroblasts.
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| Masaoka A, Gassman NR, Kedar PS, Prasad R, Hou EW, Horton JK, Bustin M, Wilson SH.
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| J Biol Chem 287(33):27648-58. doi: 10.1074/jbc.M112.370759. Epub 2012 Jun 26.
2012
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| 31 | NMNAT1, PARP1
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| Regulation of poly(ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase.
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| Zhang T, Berrocal JG, Yao J, DuMond ME, Krishnakumar R, Ruhl DD, Ryu KW, Gamble MJ, Kraus WL.
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| J Biol Chem 287(15):12405-16. doi: 10.1074/jbc.M111.304469. Epub 2012 Feb 13.
2012
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| 32 | CHD1L, DDB2, PARP1
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| PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1.
|
| Pines A, Vrouwe MG, Marteijn JA, Typas D, Luijsterburg MS, Cansoy M, Hensbergen P, Deelder A, de Groot A, Matsumoto S, Sugasawa K, Thoma N, Vermeulen W, Vrieling H, Mullenders L.
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| J Cell Biol 199(2):235-49. doi: 10.1083/jcb.201112132. Epub 2012 Oct 8.
2012
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| 33 | PARP1, RECQL5
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| Human RECQL5 participates in the removal of endogenous DNA damage.
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| Tadokoro T, Ramamoorthy M, Popuri V, May A, Tian J, Sykora P, Rybanska I, Wilson DM 3rd, Croteau DL, Bohr VA.
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| Mol Biol Cell 23(21):4273-85. doi: 10.1091/mbc.E12-02-0110. Epub 2012 Sep 12.
2012
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| 34 | PARP1, SMARCA1
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| Chromosome 19p13.3 deletion in a patient with macrocephaly, obesity, mental retardation, and behavior problems.
|
| de Smith AJ, van Haelst MM, Ellis RJ, Holder SE, Payne SJ, Hashim SK, Froguel P, Blakemore AI.
|
| Am J Med Genet A 155(5):1192-5. doi: 10.1002/ajmg.a.33986. Epub 2011 Apr 4. No abstract available.
2011
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| 35 | PARP1, PARP2, PARP3
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| Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression.
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| Boehler C, Gauthier LR, Mortusewicz O, Biard DS, Saliou JM, Bresson A, Sanglier-Cianferani S, Smith S, Schreiber V, Boussin F, Dantzer F.
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| Proc Natl Acad Sci U S A 108(7):2783-8. Epub 2011 Jan 26.
2011
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| 36 | C12orf48, PARP1
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| C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.
|
| Piao L, Nakagawa H, Ueda K, Chung S, Kashiwaya K, Eguchi H, Ohigashi H, Ishikawa O, Daigo Y, Matsuda K, Nakamura Y.
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| Genes Chromosomes Cancer 50(1):13-24.
2011
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| 37 | KIAA0020, PARP1
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| hPuf-A/KIAA0020 modulates PARP-1 cleavage upon genotoxic stress.
|
| Chang HY, Fan CC, Chu PC, Hong BE, Lee HJ, Chang MS.
|
| Cancer Res 71(3):1126-34. Epub 2011 Jan 25.
2011
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| 38 | HES1, PARP1
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| Notch/HES1-mediated PARP1 activation: a cell type-specific mechanism for tumor suppression.
|
| Kannan S, Fang W, Song G, Mullighan CG, Hammitt R, McMurray J, Zweidler-McKay PA.
|
| Blood 117(10):2891-900. Epub 2011 Jan 11.
2011
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| 39 | LDOC1, PARP1
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| Over expression of LDOC1 and PARP1, two pro-apoptotic genes, in a patient with cryptorchidism and DiGeorge anomaly.
|
| Salemi M, Castiglione R, La Vignera S, Condorelli RA, Bosco P, Vicari E, Calogero AE.
|
| Hum Cell 24(2):112-3. Epub 2011 Mar 4. No abstract available.
2011
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| 40 | KLF8, PARP1
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| Identification of poly (ADP-ribose) polymerase-1 (PARP-1) as a novel Kruppel-like factor 8-interacting and -regulating protein.
|
| Lu H, Wang X, Li T, Urvalek AM, Yu L, Li J, Zhu J, Lin Q, Peng X, Zhao J.
|
| J Biol Chem 286(23):20335-44. Epub 2011 Apr 25.
2011
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| 41 | PARP1
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| Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS).
|
| Ohanna M, Giuliano S, Bonet C, Imbert V, Hofman V, Zangari J, Bille K, Robert C, Bressac-de Paillerets B, Hofman P, Rocchi S, Peyron JF, Lacour JP, Ballotti R, Bertolotto C.
|
| Genes Dev 25(12):1245-61. doi: 10.1101/gad.625811. Epub 2011 Jun 6.
2011
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| 42 | PARP1, PHLPP1
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| PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1.
|
| Wang S, Wang H, Davis BC, Liang J, Cui R, Chen SJ, Xu ZX.
|
| Biochem Biophys Res Commun 412(2):379-84. Epub 2011 Jul 29.
2011
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| 43 | PARP1, PARP2, TOP2B
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| Poly(ADP-ribose) polymerases PARP1 and PARP2 modulate topoisomerase II beta (TOP2B) function during chromatin condensation in mouse spermiogenesis.
|
| Meyer-Ficca ML, Lonchar JD, Ihara M, Meistrich ML, Austin CA, Meyer RG.
|
| Biol Reprod 84(5):900-9. doi: 10.1095/biolreprod.110.090035. Epub 2011 Jan 12.
2011
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| 44 | PARP1, TOP2B, XRCC6
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| Topoisomerase IIβ associates with Ku70 and PARP-1 during double strand break repair of DNA in neurons.
|
| Mandraju R, Chekuri A, Bhaskar C, Duning K, Kremerskothen J, Kondapi AK.
|
| Arch Biochem Biophys 516(2):128-37. doi: 10.1016/j.abb.2011.09.017. Epub 2011 Oct 10.
2011
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| 45 | PARP1
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| Poly(ADP-ribose) polymerase 1 (PARP-1) binds to 8-oxoguanine-DNA glycosylase (OGG1).
|
| Noren Hooten N, Kompaniez K, Barnes J, Lohani A, Evans MK.
|
| J Biol Chem 286(52):44679-90. doi: 10.1074/jbc.M111.255869. Epub 2011 Nov 4.
2011
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| 46 | NCAPD2, PARP1
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| Condensin I recruitment to base damage-enriched DNA lesions is modulated by PARP1.
|
| Kong X, Stephens J, Ball AR Jr, Heale JT, Newkirk DA, Berns MW, Yokomori K.
|
| PLoS One 6(8):e23548. doi: 10.1371/journal.pone.0023548. Epub 2011 Aug 12.
2011
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| 47 | H2AFX, PARP1, TP53BP1
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| Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1.
|
| Orsburn B, Escudero B, Prakash M, Gesheva S, Liu G, Huso DL, Franco S.
|
| Mol Cell Biol 30(10):2341-52. Epub 2010 Mar 15.PMID: 20231360 2010
|
| 48 | PARP1
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| PARP1 ADP-ribosylates lysine residues of the core histone tails.
|
| Messner S, Altmeyer M, Zhao H, Pozivil A, Roschitzki B, Gehrig P, Rutishauser D, Huang D, Caflisch A, Hottiger MO.
|
| Nucleic Acids Res 38(19):6350-62. Epub 2010 Jun 4.
2010
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| 49 | PARP1
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| The roles of PARP1 in gene control and cell differentiation.
|
| Ji Y, Tulin AV.
|
| Curr Opin Genet Dev 20(5):512-8. Epub 2010 Jun 28. Review.
2010
|
| 50 | BRCA2, PALB2, PARP1, RAD51
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| Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination.
|
| Buisson R, Dion-Côté AM, Coulombe Y, Launay H, Cai H, Stasiak AZ, Stasiak A, Xia B, Masson JY.
|
| Nat Struct Mol Biol 17(10):1247-54. Epub 2010 Sep 26.
2010
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| 51 | PARP1, SMAD1, SMAD2, SMAD3, SMAD4, SMAD5, SMAD6
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| PARP-1 attenuates Smad-mediated transcription.
|
| Lönn P, van der Heide LP, Dahl M, Hellman U, Heldin CH, Moustakas A.
|
| Mol Cell 40(4):521-32.
2010
|
| 52 | CKB, PARP1, TNFSF11
|
| RANKL up-regulates brain-type creatine kinase via poly(ADP-ribose) polymerase-1 during osteoclastogenesis.
|
| Chen J, Sun Y, Mao X, Liu Q, Wu H, Chen Y.
|
| J Biol Chem 285(47):36315-21. Epub 2010 Sep 13.
2010
|
| 53 | PARP1
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| PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy.
|
| Salvati E, Scarsella M, Porru M, Rizzo A, Iachettini S, Tentori L, Graziani G, D'Incalci M, Stevens MF, Orlandi A, Passeri D, Gilson E, Zupi G, Leonetti C, Biroccio A.
|
| Oncogene 29(47):6280-93. Epub 2010 Aug 30.
2010
|
| 54 | PARP1, PARP2, PARP3
|
| PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA.
|
| Loseva O, Jemth AS, Bryant HE, Schüler H, Lehtiö L, Karlberg T, Helleday T.
|
| J Biol Chem 285(11):8054-60. Epub 2010 Jan 11.
2010
|
| 55 | PARP1
|
| PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway.
|
| Krishnakumar R, Kraus WL.
|
| Mol Cell 39(5):736-49.
2010
|
| 56 | PARG, PARP1
|
| Deletion of the nuclear isoform of poly(ADP-ribose) glycohydrolase (PARG) reveals its function in DNA repair, genomic stability and tumorigenesis.
|
| Min W, Cortes U, Herceg Z, Tong WM, Wang ZQ.
|
| Carcinogenesis 31(12):2058-65. Epub 2010 Oct 6.
2010
|
| 57 | H2AFX, PARP1, PARP2
|
| Histone gammaH2AX and poly(ADP-ribose) as clinical pharmacodynamic biomarkers.
|
| Redon CE, Nakamura AJ, Zhang YW, Ji JJ, Bonner WM, Kinders RJ, Parchment RE, Doroshow JH, Pommier Y.
|
| Clin Cancer Res 16(18):4532-42. doi: 10.1158/1078-0432.CCR-10-0523. Epub 2010 Sep 7. Review.
2010
|
| 58 | PARP1
|
| Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites.
|
| Altmeyer M, Messner S, Hassa PO, Fey M, Hottiger MO.
|
| Nucleic Acids Res 37(11):3723-38. Epub 2009 Apr 16.
2009
|
| 59 | FOXO1, FOXO3, FOXO4, FOXO6, PARP1
|
| Regulation of FOXO1-mediated transcription and cell proliferation by PARP-1.
|
| Sakamaki J, Daitoku H, Yoshimochi K, Miwa M, Fukamizu A.
|
| Biochem Biophys Res Commun 382(3):497-502. Epub 2009 Mar 10. 2009
|
| 60 | IMMT, PARP1
|
| Mitochondrial localization of PARP-1 requires interaction with mitofilin and is involved in the maintenance of mitochondrial DNA integrity.
|
| Rossi MN, Carbone M, Mostocotto C, Mancone C, Tripodi M, Maione R, Amati P.
|
| J Biol Chem 284(46):31616-24. Epub 2009 Sep 17.
2009
|
| 61 | PARP1, PARP2, PARP9
|
| Determination of Poly (ADP-ribose) polymerase (PARP) homologues in human ejaculated sperm and its correlation with sperm maturation.
|
| Jha R, Agarwal A, Mahfouz R, Paasch U, Grunewald S, Sabanegh E, Yadav SP, Sharma R.
|
| Fertil Steril 91(3):782-90. Epub 2008 Mar 12.PMID: 18339380 2009
|
| 62 | APEX1, APTX, PARP1
|
| Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage.
|
| Harris JL, Jakob B, Taucher-Scholz G, Dianov GL, Becherel OJ, Lavin MF.
|
| Hum Mol Genet 18(21):4102-17. Epub 2009 Jul 30.PMID: 19643912 2009
|
| 63 | PARP1, RNF4
|
| PARP-1 transcriptional activity is regulated by sumoylation upon heat shock.
|
| Martin N, Schwamborn K, Schreiber V, Werner A, Guillier C, Zhang XD, Bischof O, Seeler JS, Dejean A.
|
| EMBO J 28(22):3534-48. Epub 2009 Sep 24.PMID: 19779455 2009
|
| 64 | PARP1, PARP2
|
| Parp2 is required for the differentiation of post-meiotic germ cells: identification of a spermatid-specific complex containing Parp1, Parp2, TP2 and HSPA2.
|
| Quénet D, Mark M, Govin J, van Dorsselear A, Schreiber V, Khochbin S, Dantzer F.
|
| Exp Cell Res 315(16):2824-34. doi: 10.1016/j.yexcr.2009.07.003. Epub 2009 Jul 14.
2009
|
| 65 | CENPB, CENPE, CENPF, PARP1
|
| Distribution of centromeric proteins and PARP-1 during mitosis and apoptosis.
|
| Perdoni F, Bottone MG, Soldani C, Veneroni P, Alpini C, Pellicciari C, Scovassi AI.
|
| Ann N Y Acad Sci 1171:32-7. doi: 10.1111/j.1749-6632.2009.04729.x.
2009
|
| 66 | PARP1
|
| Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes.
|
| Krishnakumar R, Gamble MJ, Frizzell KM, Berrocal JG, Kininis M, Kraus WL.
|
| Science 319(5864):819-21. 2008
|
| 67 | BRCA2, PARP1
|
| Poly(ADP-ribose) polymerase-1 down-regulates BRCA2 expression through the BRCA2 promoter.
|
| Wang J, Bian C, Li J, Couch FJ, Wu K, Zhao RC.
|
| J Biol Chem 283(52):36249-56. Epub 2008 Nov 5.
2008
|
| 68 | PARP1
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| PARP1 is required for adhesion molecule expression in atherogenesis.
|
| von Lukowicz T, Hassa PO, Lohmann C, Borén J, Braunersreuther V, Mach F, Odermatt B, Gersbach M, Camici GG, Stähli BE, Tanner FC, Hottiger MO, Lüscher TF, Matter CM.
|
| Cardiovasc Res 78(1):158-66. Epub 2007 Dec 18.PMID: 18093987 2008
|
| 69 | ACP5, PARP1
|
| Poly(adp-ribose) polymerase-1 regulates Tracp gene promoter activity during RANKL-induced osteoclastogenesis.
|
| Beranger GE, Momier D, Rochet N, Carle GF, Scimeca JC.
|
| J Bone Miner Res 23(4):564-71.PMID: 18021007 2008
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| 70 | PARP1
|
| Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme activity and contains a novel zinc-ribbon motif.
|
| Tao Z, Gao P, Hoffman DW, Liu HW.
|
| Biochemistry 47(21):5804-13. Epub 2008 May 2.PMID: 18452307 2008
|
| 71 | DYX1C1, GTF2I, PARP1, SFPQ
|
| The complex of TFII-I, PARP1, and SFPQ proteins regulates the DYX1C1 gene implicated in neuronal migration and dyslexia.
|
| Tapia-Páez I, Tammimies K, Massinen S, Roy AL, Kere J.
|
| FASEB J 22(8):3001-9. Epub 2008 Apr 29.
2008
|
| 72 | PARP1, SMARCA1
|
| The nucleosome-remodeling ATPase ISWI is regulated by poly-ADP-ribosylation.
|
| Sala A, La Rocca G, Burgio G, Kotova E, Di Gesù D, Collesano M, Ingrassia AM, Tulin AV, Corona DF.
|
| PLoS Biol 6(10):e252.
2008
|
| 73 | DEK,PARP1,SET
|
| SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery.
|
| Gamble MJ, Fisher RP.
|
| Nat Struct Mol Biol 14(6):548-55. Epub 2007 May 27. 2007
|
| 74 | PARP1
|
| Genetic sequence variations and ADPRT haplotype analysis in French Canadian families with high risk of breast cancer.
|
| Durocher F, Labrie Y, Ouellette G; INHERIT BRCAs, Simard J.
|
| J Hum Genet 52(12):963-77. Epub 2007 Oct 18. 2007
|
| 75 | PARP1, PARP2
|
| Oxidative DNA damage repair and parp 1 and parp 2 expression in Epstein-Barr virus-immortalized B lymphocyte cells from young subjects, old subjects, and centenarians.
|
| Chevanne M, Calia C, Zampieri M, Cecchinelli B, Caldini R, Monti D, Bucci L, Franceschi C, Caiafa P.
|
| Rejuvenation Res 10(2):191-204. 2007
|
| 76 | PARP1
|
| Poly (ADP-ribose) polymerase-1 (PARP-1) genetic variants are protective against Parkinson's disease.
|
| Infante J, Sánchez-Juan P, Mateo I, Rodríguez-Rodríguez E, Sánchez-Quintana C, Llorca J, Fontalba A, Terrazas J, Oterino A, Berciano J, Combarros O.
|
| J Neurol Sci 256(1-2):68-70. Epub 2007 Mar 23.
2007
|
| 77 | PARP1, KIF4A, KIF4B
|
| KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity.
|
| Midorikawa R, Takei Y, Hirokawa N.
|
| Cell 125(2):371-83. 2006
|
| 78 | PARP1
|
| Expression of the Gene Encoding Poly(ADP-ribose) Polymerase-1 Is Modulated by Fibronectin during Corneal Wound Healing.
|
| Zaniolo K, Gingras ME, Audette M, Guerin SL.
|
| Invest Ophthalmol Vis Sci 47(10):4199-210. 2006
|
| 79 | NCAPH, PARP1, XRCC1
|
| Condensin I interacts with the PARP-1-XRCC1 complex and functions in DNA single-strand break repair.
|
| Heale JT, Ball AR Jr, Schmiesing JA, Kim JS, Kong X, Zhou S, Hudson DF, Earnshaw WC, Yokomori K.
|
| Mol Cell 21(6):837-48. 2006
|
| 80 | PARP1, PARP2, NKX2-1
|
| PARP-2 interacts with TTF-1 and regulates expression of surfactant protein-B.
|
| Maeda Y, Hunter TC, Loudy DE, DavŽ V, Schreiber V, Whitsett JA.
|
| J Biol Chem 281(14):9600-6. Epub 2006 Feb 6. 2006
|
| 81 | PARP1, TERF2
|
| PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres.
|
| Gomez M, Wu J, Schreiber V, Dunlap J, Dantzer F, Wang Y, Liu Y.
|
| Mol Biol Cell 17(4):1686-96. Epub 2006 Jan 25. 2006
|
| 82 | PARP1,SNCA
|
| Regulation of alpha-synuclein expression by poly (ADP ribose) polymerase-1 (PARP-1) binding to the NACP-Rep1 polymorphic site upstream of the SNCA gene.
|
| Chiba-Falek O, Kowalak JA, Smulson ME, Nussbaum RL.
|
| Am J Hum Genet 76(3):478-92. Epub 2005 Jan 25. 2005
|
| 83 | AURKB, PARP1
|
| Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage.
|
| Monaco L, Kolthur-Seetharam U, Loury R, Murcia JM, de Murcia G, Sassone-Corsi P.
|
| Proc Natl Acad Sci U S A 102(40):14244-8. Epub 2005 Sep 22. 2005
|
| 84 | PARP1, TNKS
|
| Tankyrase-1 overexpression reduces genotoxin-induced cell death by inhibiting PARP1.
|
| Yeh TY, Sbodio JI, Nguyen MT, Meyer TN, Lee RM, Chi NW.
|
| Mol Cell Biochem 276(1-2):183-92. 2005
|
| 85 | APTX, XRCC1, TP53, PARP1
|
| Aprataxin, a novel protein that protects against genotoxic stress.
|
| Gueven N, Becherel OJ, Kijas AW, Chen P, Howe O, Rudolph JH, Gatti R, Date H, Onodera O, Taucher-Scholz G, Lavin MF.
|
| Hum Mol Genet 13(10):1081-93. Epub 2004 Mar 25. 2004
|
| 86 | TNKS, TERF2, TINF2, PARP1
|
| TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex.
|
| Ye JZ, de Lange T.
|
| Nat Genet 36(6):618-23. Epub 2004 May 09. 2004
|
| 87 | PARP8, PARP9, PARP14, PARP15, PARP16, PARP6, PARP11, PARP10, PARP1, PARP2
|
| The PARP superfamily.
|
| Ame JC, Spenlehauer C, de Murcia G.
|
| Bioessays 26(8):882-93. Review. 2004
|
| 88 | PARP1, PARP2
|
| Poly(ADP-ribose) reactivates stalled DNA topoisomerase I and Induces DNA strand break resealing.
|
| Malanga M, Althaus FR.
|
| J Biol Chem 279(7):5244-8. Epub 2003 Dec 29. 2004
|
| 89 | TERF2IP, TERF1, TERF1, PARP1
|
| The human Rap1 protein complex and modulation of telomere length.
|
| O'Connor MS, Safari A, Liu D, Qin J, Songyang Z.
|
| J Biol Chem 279(27):28585-91. Epub 2004 Apr 20. 2004
|
| 90 | PARP1, XRCC1, APTX
|
| The FHA domain of aprataxin interacts with the C-terminal region of XRCC1.
|
| Date H, Igarashi S, Sano Y, Takahashi T, Takahashi T, Takano H, Tsuji S, Nishizawa M, Onodera O.
|
| Biochem Biophys Res Commun 325(4):1279-85. 2004
|
| 91 | PARP1, RANGAP1, BIRC2, TEGT, MCL1, SENP1
|
| Isolation of differentially expressed genes in NPM-ALK-positive anaplastic large cell lymphoma.
|
| Villalva C, Trempat P, Greenland C, Thomas C, Girard JP, Moebius F, Delsol G, Brousset P.
|
| Br J Haematol 118(3):791-8. 2002
|
| 92 | PARP1
|
| Poly(ADP-ribose) polymerase at active centromeres and neocentromeres at metaphase.
|
| Earle E, Saxena A, MacDonald A, Hudson DF, Shaffer LG, Saffery R, Cancilla MR, Cutts SM, Howman E, Choo KH.
|
| Hum Mol Genet 9(2):187-94 2000
|
| 93 | PARP1, SLEB1
|
| PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus.
|
| Tsao BP, et al.
|
| J Clin Invest 103(8):1135-40. 1999
|
| 94 | PARP2 , PARP3, PARP1
|
| A human Poly(ADP-ribose) polymerase gene family (ADPRTL): cDNA cloning of two novel Poly(ADP-ribose) polymerase homologues.
|
| Johansson M.
|
| Genomics 57(3):442-5. 1999
|
| 95 | PARP1
|
| Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion.
|
| Ha HC, Snyder SH.
|
| Proc Natl Acad Sci U S A 96(24):13978-82 1999
|
| 96 | PARP1, FRA1H, RN5S1@
|
| Assignment of FRA1H common fragile site to human chromosome band 1q42.1 proximal to the nuclear NAD+ADP-ribosyltransferase gene (ADPRT) and to the main 5S rRNA gene locus.
|
| Pelliccia F, et al.
|
| Cytogenet Cell Genet 82 : 121-122. 1998
|
| 97 | PARP1, TH
|
| Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2).
|
| De Benedictis G, et al.
|
| Eur J Hum Genet 6 : 534-541. 1998
|
| 98 | PARP1, CASP3
|
| Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis.
|
| Nicholson DW, Ali A, Thornberry NA, Vaillancourt JP, Ding CK, Gallant M, Gareau Y, Griffin PR, Labelle M, Lazebnik YA, et al.
|
| Nature 376(6535):37-43. 1995
|
| 99 | PARP1
|
| Dinucleotide repeat polymorphism at the human Poly (ADP-Ribose) polymerase gene (PPOL).
|
| Fougerousse F, et al.
|
| Nucleic Acids Res 20 : 1166. 1992
|
| 100 | PARP1
|
| The human poly(ADP-ribose) polymerase nuclear localization signal is a bipartite element functionally separate from DNA binding and catalytic activity.
|
| Schreiber V, Molinete M, Boeuf H, de Murcia G, Ménissier-de Murcia J.
|
| EMBO J 11(9):3263-9.
1992
|
| 101 | PARP1
|
| A mutant allele common to the type 1 adenine phosphoribosyltransferase deficiency in Japanese subjects.
|
| Mimori A, et al.
|
| Am J Hum Genet 48 : 103-107. 1991
|
| 102 | PARP1,PARP1P1,PARP1P2
|
| Chromosomal sublocalization of the gene for human poly (ADP-ribose) polymerase (NAD+ ADP-ribosyltransferase) at 1q41-42.
|
| Zabel BU, et al.
|
| (HGM10) Cytogenet Cell Genet 51 : 1115. 1989
|
| 103 | PARP1,PARP1P1,PARP1P2
|
| Human nuclear NAD+/ADP-ribosyltransferase: localization of the gene on chromosome 1q41-q42 and expression of an active human enzyme in Escherichia coli.
|
| Herzog H, et al.
|
| Proc Natl Acad Sci U S A 86 : 3514-3518. 1989
|
| 104 | PARP1,PARP1P1,PARP1P2
|
| cDNA sequence, protein structure, and chromosomal location of the human gene for poly (ADP-ribose) polymerase.
|
| Cherney BW, et al.
|
| Proc Natl Acad Sci U S A 84 : 8370-8374. 1987
|
| 105 | PARP1,PARP1P1,PARP1P2
|
| Human poly(ADP-ribose) polymerase sequences are located on chromosomes 1,13, and 14.
|
| McBride OW, et al.
|
| (HGM9) Cytogenet Cell Genet 46 : 659. 1987
|
| 106 | PARP1
|
| Cloning and expression of cDNA for human poly(ADP-ribose) polymerase.
|
| Alkhatib HM, et al.
|
| Proc Natl Acad Sci U S A 84 : 1224-1228. 1987
|