Citations for
1IRF1, PARP1
Inhibition of PARP1 Increases IRF-dependent Gene Transcription in Jurkat Cells.
Wang C, Du M, Huang D, Huang K, Huang K.
Curr Med Sci 39(3):356-362. doi: 10.1007/s11596-019-2043-1. Epub 2019 Jun 17. 2019
2PARP1, SEPTIN4
Septin4 as a novel binding partner of PARP1 contributes to oxidative stress induced human umbilical vein endothelial cells injure.
Zhang N, Zhang Y, Zhao S, Sun Y.
Biochem Biophys Res Commun 496(2):621-627. doi: 10.1016/j.bbrc.2018.01.105. 2018
3DDB2, PARP1, XPC
Poly(ADP-ribose) polymerase 1 escorts XPC to UV-induced DNA lesions during nucleotide excision repair.
Robu M, Shah RG, Purohit NK, Zhou P, Naegeli H, Shah GM.
Proc Natl Acad Sci U S A 114(33):E6847-E6856. doi: 10.1073/pnas.1706981114. Epub 2017 Jul 31. 2017
4PARP1, PARP2, PNKP, XRCC1
Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin.
Hanzlikova H, Gittens W, Krejcikova K, Zeng Z, Caldecott KW.
Nucleic Acids Res 45(5):2546-2557. doi: 10.1093/nar/gkw1246. 2017
5CASP1, NOS2, PARP1
Epigenetic regulation of nitric oxide synthase 2, inducible (Nos2) by NLRC4 inflammasomes involves PARP1 cleavage.
Buzzo CL, Medina T, Branco LM, Lage SL, Ferreira LC, Amarante-Mendes GP, Hottiger MO, De Carvalho DD, Bortoluci KR.
Sci Rep 7:41686. doi: 10.1038/srep41686. 2017
6BLM, PARP1, RECQL, RECQL4, RECQL5, WRN
RecQ helicases and PARP1 team up in maintaining genome integrity.
Veith S, Mangerich A.
Ageing Res Rev 23(Pt A):12-28. doi: 10.1016/j.arr.2014.12.006. Epub 2014 Dec 30. Review. 2015
7PARP1
Poly(ADP-ribose)polymerase 1 stimulates the AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1.
Lebedeva NA, Anarbaev RO, Sukhanova M, Vasil'eva IA, Rechkunova NI, Lavrik OI.
Biosci Rep 35(4). pii: e00230. doi: 10.1042/BSR20140192. 2015
8PARP1, RECQL5, WRN
Differential and Concordant Roles for Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribose) in Regulating WRN and RECQL5 Activities.
Khadka P, Hsu JK, Veith S, Tadokoro T, Shamanna RA, Mangerich A, Croteau DL, Bohr VA.
Mol Cell Biol 35(23):3974-89. doi: 10.1128/MCB.00427-15. Epub 2015 Sep 21. 2015
9PARP1, UHRF1
Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitine-protein ligase UHRF1 and modulates UHRF1 biological functions.
De Vos M, El Ramy R, Quénet D, Wolf P, Spada F, Magroun N, Babbio F, Schreiber V, Leonhardt H, Bonapace IM, Dantzer F.
J Biol Chem Biol Chem. 2014 Apr 29. [Epub ahead of print] 2014
10FOXP3, PARP1
PARP-1 controls immunosuppressive function of regulatory T cells by destabilizing Foxp3.
Zhang P, Maruyama T, Konkel JE, Abbatiello B, Zamarron B, Wang ZQ, Chen W.
PLoS One 8(8):e71590. doi: 10.1371/journal.pone.0071590. eCollection 2013. 2013
11PARP1
PARP1 represses PAP and inhibits polyadenylation during heat shock.
Di Giammartino DC, Shi Y, Manley JL.
Mol Cell 49(1):7-17. doi: 10.1016/j.molcel.2012.11.005. Epub 2012 Dec 6. 2013
12BCL6, PARP1, PRKAA2
AMPKα2 exerts its anti-inflammatory effects through PARP-1 and Bcl-6.
Gongol B, Marin T, Peng IC, Woo B, Martin M, King S, Sun W, Johnson DA, Chien S, Shyy JY.
Proc Natl Acad Sci U S A 110(8):3161-6. doi: 10.1073/pnas.1222051110. Epub 2013 Feb 4. 2013
13ETS1, PARP1
The level of Ets-1 protein is regulated by poly(ADP-ribose) polymerase-1 (PARP-1) in cancer cells to prevent DNA damage.
Legrand AJ, Choul-Li S, Spriet C, Idziorek T, Vicogne D, Drobecq H, Dantzer F, Villeret V, Aumercier M.
PLoS One 8(2):e55883. doi: 10.1371/journal.pone.0055883. Epub 2013 Feb 6. 2013
14PARP1, RECQL
Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition.
Berti M, Ray Chaudhuri A, Thangavel S, Gomathinayagam S, Kenig S, Vujanovic M, Odreman F, Glatter T, Graziano S, Mendoza-Maldonado R, Marino F, Lucic B, Biasin V, Gstaiger M, Aebersold R, Sidorova JM, Monnat RJ Jr, Lopes M, Vindigni A.
Nat Struct Mol Biol 20(3):347-54. doi: 10.1038/nsmb.2501. Epub 2013 Feb 10. 2013
15PARP1, TET2
Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2.
Doege CA, Inoue K, Yamashita T, Rhee DB, Travis S, Fujita R, Guarnieri P, Bhagat G, Vanti WB, Shih A, Levine RL, Nik S, Chen EI, Abeliovich A.
Nature 488(7413):652-5. doi: 10.1038/nature11333. 2012
16PARP1, PARP2
Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors.
Murai J, Huang SY, Das BB, Renaud A, Zhang Y, Doroshow JH, Ji J, Takeda S, Pommier Y.
Cancer Res 72(21):5588-99. doi: 10.1158/0008-5472.CAN-12-2753. 2012
17PARP1, PARP2
The role of PARP-1 and PARP-2 enzymes in metabolic regulation and disease.
Bai P, Cantó C.
Cell Metab 16(3):290-5. doi: 10.1016/j.cmet.2012.06.016. Epub 2012 Aug 23. Review. 2012
18PARP1, PARP2
Cell death and autophagy under oxidative stress: roles of poly(ADP-Ribose) polymerases and Ca(2+).
Wyrsch P, Blenn C, Bader J, Althaus FR.
Mol Cell Biol 32(17):3541-53. doi: 10.1128/MCB.00437-12. Epub 2012 Jul 2. 2012
19PARP1, SOX2
SRY (sex determining region Y)-box2 (Sox2)/poly ADP-ribose polymerase 1 (Parp1) complexes regulate pluripotency.
Lai YS, Chang CW, Pawlik KM, Zhou D, Renfrow MB, Townes TM.
Proc Natl Acad Sci U S A 109(10):3772-7. doi: 10.1073/pnas.1108595109. Epub 2012 Feb 23. 2012
20NEIL1, PARP1
Coordination of DNA repair by NEIL1 and PARP-1: a possible link to aging.
Noren Hooten N, Fitzpatrick M, Kompaniez K, Jacob KD, Moore BR, Nagle J, Barnes J, Lohani A, Evans MK.
Aging (Albany NY) 4(10):674-85. 2012
21CHFR, PARP1
CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation.
Kashima L, Idogawa M, Mita H, Shitashige M, Yamada T, Ogi K, Suzuki H, Toyota M, Ariga H, Sasaki Y, Tokino T.
J Biol Chem 287(16):12975-84. doi: 10.1074/jbc.M111.321828. Epub 2012 Feb 15. 2012
22BAZ2A, PARP1
Inheritance of silent rDNA chromatin is mediated by PARP1 via noncoding RNA.
Guetg C, Scheifele F, Rosenthal F, Hottiger MO, Santoro R.
Mol Cell 45(6):790-800. doi: 10.1016/j.molcel.2012.01.024. Epub 2012 Mar 8. 2012
23PARP1
Increased transcript level of poly(ADP-ribose) polymerase (PARP-1) in human tricuspid compared with bicuspid aortic valves correlates with the stenosis severity.
Nagy E, Caidahl K, Franco-Cereceda A, Bäck M.
Biochem Biophys Res Commun 420(3):671-5. doi: 10.1016/j.bbrc.2012.03.064. Epub 2012 Mar 17. 2012
24PARP1
Increased transcript level of poly(ADP-ribose) polymerase (PARP-1) in human tricuspid compared with bicuspid aortic valves correlates with the stenosis severity.
Nagy E, Caidahl K, Franco-Cereceda A, Bäck M.
Biochem Biophys Res Commun 420(3):671-5. doi: 10.1016/j.bbrc.2012.03.064. Epub 2012 Mar 17. 2012
25HOXB7, PARP1
ADP ribosylation by PARP-1 suppresses HOXB7 transcriptional activity.
Wu X, Ellmann S, Rubin E, Gil M, Jin K, Han L, Chen H, Kwon EM, Guo J, Ha HC, Sukumar S.
PLoS One 7(7):e40644. doi: 10.1371/journal.pone.0040644. Epub 2012 Jul 23. 2012
26PARP1, SH3BP2
Cloning and characterization of the human SH3BP2 promoter.
Fan C, Gaivin RJ, Marth TA, Willard B, Levine MA, Lietman SA.
Biochem Biophys Res Commun 425(1):25-32. doi: 10.1016/j.bbrc.2012.07.043. Epub 2012 Jul 17. 2012
27PARP1
Structural basis for DNA damage-dependent poly(ADP-ribosyl)ation by human PARP-1.
Langelier MF, Planck JL, Roy S, Pascal JM.
Science 336(6082):728-32. doi: 10.1126/science.1216338. 2012
28HMGN1, PARP1
HMGN1 protein regulates poly(ADP-ribose) polymerase-1 (PARP-1) self-PARylation in mouse fibroblasts.
Masaoka A, Gassman NR, Kedar PS, Prasad R, Hou EW, Horton JK, Bustin M, Wilson SH.
J Biol Chem 287(33):27648-58. doi: 10.1074/jbc.M112.370759. Epub 2012 Jun 26. 2012
29NMNAT1, PARP1
Regulation of poly(ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase.
Zhang T, Berrocal JG, Yao J, DuMond ME, Krishnakumar R, Ruhl DD, Ryu KW, Gamble MJ, Kraus WL.
J Biol Chem 287(15):12405-16. doi: 10.1074/jbc.M111.304469. Epub 2012 Feb 13. 2012
30CHD1L, DDB2, PARP1
PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1.
Pines A, Vrouwe MG, Marteijn JA, Typas D, Luijsterburg MS, Cansoy M, Hensbergen P, Deelder A, de Groot A, Matsumoto S, Sugasawa K, Thoma N, Vermeulen W, Vrieling H, Mullenders L.
J Cell Biol 199(2):235-49. doi: 10.1083/jcb.201112132. Epub 2012 Oct 8. 2012
31PARP1, RECQL5
Human RECQL5 participates in the removal of endogenous DNA damage.
Tadokoro T, Ramamoorthy M, Popuri V, May A, Tian J, Sykora P, Rybanska I, Wilson DM 3rd, Croteau DL, Bohr VA.
Mol Biol Cell 23(21):4273-85. doi: 10.1091/mbc.E12-02-0110. Epub 2012 Sep 12. 2012
32PARP1, SMARCA1
Chromosome 19p13.3 deletion in a patient with macrocephaly, obesity, mental retardation, and behavior problems.
de Smith AJ, van Haelst MM, Ellis RJ, Holder SE, Payne SJ, Hashim SK, Froguel P, Blakemore AI.
Am J Med Genet A 155(5):1192-5. doi: 10.1002/ajmg.a.33986. Epub 2011 Apr 4. No abstract available. 2011
33PARP1, PARP2, PARP3
Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression.
Boehler C, Gauthier LR, Mortusewicz O, Biard DS, Saliou JM, Bresson A, Sanglier-Cianferani S, Smith S, Schreiber V, Boussin F, Dantzer F.
Proc Natl Acad Sci U S A 108(7):2783-8. Epub 2011 Jan 26. 2011
34C12orf48, PARP1
C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.
Piao L, Nakagawa H, Ueda K, Chung S, Kashiwaya K, Eguchi H, Ohigashi H, Ishikawa O, Daigo Y, Matsuda K, Nakamura Y.
Genes Chromosomes Cancer 50(1):13-24. 2011
35KIAA0020, PARP1
hPuf-A/KIAA0020 modulates PARP-1 cleavage upon genotoxic stress.
Chang HY, Fan CC, Chu PC, Hong BE, Lee HJ, Chang MS.
Cancer Res 71(3):1126-34. Epub 2011 Jan 25. 2011
36HES1, PARP1
Notch/HES1-mediated PARP1 activation: a cell type-specific mechanism for tumor suppression.
Kannan S, Fang W, Song G, Mullighan CG, Hammitt R, McMurray J, Zweidler-McKay PA.
Blood 117(10):2891-900. Epub 2011 Jan 11. 2011
37LDOC1, PARP1
Over expression of LDOC1 and PARP1, two pro-apoptotic genes, in a patient with cryptorchidism and DiGeorge anomaly.
Salemi M, Castiglione R, La Vignera S, Condorelli RA, Bosco P, Vicari E, Calogero AE.
Hum Cell 24(2):112-3. Epub 2011 Mar 4. No abstract available. 2011
38KLF8, PARP1
Identification of poly (ADP-ribose) polymerase-1 (PARP-1) as a novel Kruppel-like factor 8-interacting and -regulating protein.
Lu H, Wang X, Li T, Urvalek AM, Yu L, Li J, Zhu J, Lin Q, Peng X, Zhao J.
J Biol Chem 286(23):20335-44. Epub 2011 Apr 25. 2011
39PARP1
Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS).
Ohanna M, Giuliano S, Bonet C, Imbert V, Hofman V, Zangari J, Bille K, Robert C, Bressac-de Paillerets B, Hofman P, Rocchi S, Peyron JF, Lacour JP, Ballotti R, Bertolotto C.
Genes Dev 25(12):1245-61. doi: 10.1101/gad.625811. Epub 2011 Jun 6. 2011
40PARP1, PHLPP1
PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1.
Wang S, Wang H, Davis BC, Liang J, Cui R, Chen SJ, Xu ZX.
Biochem Biophys Res Commun 412(2):379-84. Epub 2011 Jul 29. 2011
41PARP1, PARP2, TOP2B
Poly(ADP-ribose) polymerases PARP1 and PARP2 modulate topoisomerase II beta (TOP2B) function during chromatin condensation in mouse spermiogenesis.
Meyer-Ficca ML, Lonchar JD, Ihara M, Meistrich ML, Austin CA, Meyer RG.
Biol Reprod 84(5):900-9. doi: 10.1095/biolreprod.110.090035. Epub 2011 Jan 12. 2011
42PARP1, TOP2B, XRCC6
Topoisomerase IIβ associates with Ku70 and PARP-1 during double strand break repair of DNA in neurons.
Mandraju R, Chekuri A, Bhaskar C, Duning K, Kremerskothen J, Kondapi AK.
Arch Biochem Biophys 516(2):128-37. doi: 10.1016/j.abb.2011.09.017. Epub 2011 Oct 10. 2011
43PARP1
Poly(ADP-ribose) polymerase 1 (PARP-1) binds to 8-oxoguanine-DNA glycosylase (OGG1).
Noren Hooten N, Kompaniez K, Barnes J, Lohani A, Evans MK.
J Biol Chem 286(52):44679-90. doi: 10.1074/jbc.M111.255869. Epub 2011 Nov 4. 2011
44NCAPD2, PARP1
Condensin I recruitment to base damage-enriched DNA lesions is modulated by PARP1.
Kong X, Stephens J, Ball AR Jr, Heale JT, Newkirk DA, Berns MW, Yokomori K.
PLoS One 6(8):e23548. doi: 10.1371/journal.pone.0023548. Epub 2011 Aug 12. 2011
45H2AFX, PARP1, TP53BP1
Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1.
Orsburn B, Escudero B, Prakash M, Gesheva S, Liu G, Huso DL, Franco S.
Mol Cell Biol 30(10):2341-52. Epub 2010 Mar 15.PMID: 20231360 2010
46PARP1
PARP1 ADP-ribosylates lysine residues of the core histone tails.
Messner S, Altmeyer M, Zhao H, Pozivil A, Roschitzki B, Gehrig P, Rutishauser D, Huang D, Caflisch A, Hottiger MO.
Nucleic Acids Res 38(19):6350-62. Epub 2010 Jun 4. 2010
47PARP1
The roles of PARP1 in gene control and cell differentiation.
Ji Y, Tulin AV.
Curr Opin Genet Dev 20(5):512-8. Epub 2010 Jun 28. Review. 2010
48BRCA2, PALB2, PARP1, RAD51
Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination.
Buisson R, Dion-Côté AM, Coulombe Y, Launay H, Cai H, Stasiak AZ, Stasiak A, Xia B, Masson JY.
Nat Struct Mol Biol 17(10):1247-54. Epub 2010 Sep 26. 2010
49PARP1, SMAD1, SMAD2, SMAD3, SMAD4, SMAD5, SMAD6
PARP-1 attenuates Smad-mediated transcription.
Lönn P, van der Heide LP, Dahl M, Hellman U, Heldin CH, Moustakas A.
Mol Cell 40(4):521-32. 2010
50CKB, PARP1, TNFSF11
RANKL up-regulates brain-type creatine kinase via poly(ADP-ribose) polymerase-1 during osteoclastogenesis.
Chen J, Sun Y, Mao X, Liu Q, Wu H, Chen Y.
J Biol Chem 285(47):36315-21. Epub 2010 Sep 13. 2010
51PARP1
PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy.
Salvati E, Scarsella M, Porru M, Rizzo A, Iachettini S, Tentori L, Graziani G, D'Incalci M, Stevens MF, Orlandi A, Passeri D, Gilson E, Zupi G, Leonetti C, Biroccio A.
Oncogene 29(47):6280-93. Epub 2010 Aug 30. 2010
52PARP1, PARP2, PARP3
PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA.
Loseva O, Jemth AS, Bryant HE, Schüler H, Lehtiö L, Karlberg T, Helleday T.
J Biol Chem 285(11):8054-60. Epub 2010 Jan 11. 2010
53PARP1
PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway.
Krishnakumar R, Kraus WL.
Mol Cell 39(5):736-49. 2010
54PARG, PARP1
Deletion of the nuclear isoform of poly(ADP-ribose) glycohydrolase (PARG) reveals its function in DNA repair, genomic stability and tumorigenesis.
Min W, Cortes U, Herceg Z, Tong WM, Wang ZQ.
Carcinogenesis 31(12):2058-65. Epub 2010 Oct 6. 2010
55H2AFX, PARP1, PARP2
Histone gammaH2AX and poly(ADP-ribose) as clinical pharmacodynamic biomarkers.
Redon CE, Nakamura AJ, Zhang YW, Ji JJ, Bonner WM, Kinders RJ, Parchment RE, Doroshow JH, Pommier Y.
Clin Cancer Res 16(18):4532-42. doi: 10.1158/1078-0432.CCR-10-0523. Epub 2010 Sep 7. Review. 2010
56PARP1
Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites.
Altmeyer M, Messner S, Hassa PO, Fey M, Hottiger MO.
Nucleic Acids Res 37(11):3723-38. Epub 2009 Apr 16. 2009
57FOXO1, FOXO3, FOXO4, FOXO6, PARP1
Regulation of FOXO1-mediated transcription and cell proliferation by PARP-1.
Sakamaki J, Daitoku H, Yoshimochi K, Miwa M, Fukamizu A.
Biochem Biophys Res Commun 382(3):497-502. Epub 2009 Mar 10. 2009
58IMMT, PARP1
Mitochondrial localization of PARP-1 requires interaction with mitofilin and is involved in the maintenance of mitochondrial DNA integrity.
Rossi MN, Carbone M, Mostocotto C, Mancone C, Tripodi M, Maione R, Amati P.
J Biol Chem 284(46):31616-24. Epub 2009 Sep 17. 2009
59PARP1, PARP2, PARP9
Determination of Poly (ADP-ribose) polymerase (PARP) homologues in human ejaculated sperm and its correlation with sperm maturation.
Jha R, Agarwal A, Mahfouz R, Paasch U, Grunewald S, Sabanegh E, Yadav SP, Sharma R.
Fertil Steril 91(3):782-90. Epub 2008 Mar 12.PMID: 18339380 2009
60APEX1, APTX, PARP1
Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage.
Harris JL, Jakob B, Taucher-Scholz G, Dianov GL, Becherel OJ, Lavin MF.
Hum Mol Genet 18(21):4102-17. Epub 2009 Jul 30.PMID: 19643912 2009
61PARP1, RNF4
PARP-1 transcriptional activity is regulated by sumoylation upon heat shock.
Martin N, Schwamborn K, Schreiber V, Werner A, Guillier C, Zhang XD, Bischof O, Seeler JS, Dejean A.
EMBO J 28(22):3534-48. Epub 2009 Sep 24.PMID: 19779455 2009
62PARP1, PARP2
Parp2 is required for the differentiation of post-meiotic germ cells: identification of a spermatid-specific complex containing Parp1, Parp2, TP2 and HSPA2.
Quénet D, Mark M, Govin J, van Dorsselear A, Schreiber V, Khochbin S, Dantzer F.
Exp Cell Res 315(16):2824-34. doi: 10.1016/j.yexcr.2009.07.003. Epub 2009 Jul 14. 2009
63CENPB, CENPE, CENPF, PARP1
Distribution of centromeric proteins and PARP-1 during mitosis and apoptosis.
Perdoni F, Bottone MG, Soldani C, Veneroni P, Alpini C, Pellicciari C, Scovassi AI.
Ann N Y Acad Sci 1171:32-7. doi: 10.1111/j.1749-6632.2009.04729.x. 2009
64PARP1
Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes.
Krishnakumar R, Gamble MJ, Frizzell KM, Berrocal JG, Kininis M, Kraus WL.
Science 319(5864):819-21. 2008
65BRCA2, PARP1
Poly(ADP-ribose) polymerase-1 down-regulates BRCA2 expression through the BRCA2 promoter.
Wang J, Bian C, Li J, Couch FJ, Wu K, Zhao RC.
J Biol Chem 283(52):36249-56. Epub 2008 Nov 5. 2008
66PARP1
PARP1 is required for adhesion molecule expression in atherogenesis.
von Lukowicz T, Hassa PO, Lohmann C, Borén J, Braunersreuther V, Mach F, Odermatt B, Gersbach M, Camici GG, Stähli BE, Tanner FC, Hottiger MO, Lüscher TF, Matter CM.
Cardiovasc Res 78(1):158-66. Epub 2007 Dec 18.PMID: 18093987 2008
67ACP5, PARP1
Poly(adp-ribose) polymerase-1 regulates Tracp gene promoter activity during RANKL-induced osteoclastogenesis.
Beranger GE, Momier D, Rochet N, Carle GF, Scimeca JC.
J Bone Miner Res 23(4):564-71.PMID: 18021007 2008
68PARP1
Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme activity and contains a novel zinc-ribbon motif.
Tao Z, Gao P, Hoffman DW, Liu HW.
Biochemistry 47(21):5804-13. Epub 2008 May 2.PMID: 18452307 2008
69DYX1C1, GTF2I, PARP1, SFPQ
The complex of TFII-I, PARP1, and SFPQ proteins regulates the DYX1C1 gene implicated in neuronal migration and dyslexia.
Tapia-Páez I, Tammimies K, Massinen S, Roy AL, Kere J.
FASEB J 22(8):3001-9. Epub 2008 Apr 29. 2008
70PARP1, SMARCA1
The nucleosome-remodeling ATPase ISWI is regulated by poly-ADP-ribosylation.
Sala A, La Rocca G, Burgio G, Kotova E, Di Gesù D, Collesano M, Ingrassia AM, Tulin AV, Corona DF.
PLoS Biol 6(10):e252. 2008
71DEK,PARP1,SET
SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery.
Gamble MJ, Fisher RP.
Nat Struct Mol Biol 14(6):548-55. Epub 2007 May 27. 2007
72PARP1
Genetic sequence variations and ADPRT haplotype analysis in French Canadian families with high risk of breast cancer.
Durocher F, Labrie Y, Ouellette G; INHERIT BRCAs, Simard J.
J Hum Genet 52(12):963-77. Epub 2007 Oct 18. 2007
73PARP1, PARP2
Oxidative DNA damage repair and parp 1 and parp 2 expression in Epstein-Barr virus-immortalized B lymphocyte cells from young subjects, old subjects, and centenarians.
Chevanne M, Calia C, Zampieri M, Cecchinelli B, Caldini R, Monti D, Bucci L, Franceschi C, Caiafa P.
Rejuvenation Res 10(2):191-204. 2007
74PARP1
Poly (ADP-ribose) polymerase-1 (PARP-1) genetic variants are protective against Parkinson's disease.
Infante J, Sánchez-Juan P, Mateo I, Rodríguez-Rodríguez E, Sánchez-Quintana C, Llorca J, Fontalba A, Terrazas J, Oterino A, Berciano J, Combarros O.
J Neurol Sci 256(1-2):68-70. Epub 2007 Mar 23. 2007
75PARP1, KIF4A, KIF4B
KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity.
Midorikawa R, Takei Y, Hirokawa N.
Cell 125(2):371-83. 2006
76PARP1
Expression of the Gene Encoding Poly(ADP-ribose) Polymerase-1 Is Modulated by Fibronectin during Corneal Wound Healing.
Zaniolo K, Gingras ME, Audette M, Guerin SL.
Invest Ophthalmol Vis Sci 47(10):4199-210. 2006
77NCAPH, PARP1, XRCC1
Condensin I interacts with the PARP-1-XRCC1 complex and functions in DNA single-strand break repair.
Heale JT, Ball AR Jr, Schmiesing JA, Kim JS, Kong X, Zhou S, Hudson DF, Earnshaw WC, Yokomori K.
Mol Cell 21(6):837-48. 2006
78PARP1, PARP2, NKX2-1
PARP-2 interacts with TTF-1 and regulates expression of surfactant protein-B.
Maeda Y, Hunter TC, Loudy DE, DavŽ V, Schreiber V, Whitsett JA.
J Biol Chem 281(14):9600-6. Epub 2006 Feb 6. 2006
79PARP1, TERF2
PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres.
Gomez M, Wu J, Schreiber V, Dunlap J, Dantzer F, Wang Y, Liu Y.
Mol Biol Cell 17(4):1686-96. Epub 2006 Jan 25. 2006
80PARP1,SNCA
Regulation of alpha-synuclein expression by poly (ADP ribose) polymerase-1 (PARP-1) binding to the NACP-Rep1 polymorphic site upstream of the SNCA gene.
Chiba-Falek O, Kowalak JA, Smulson ME, Nussbaum RL.
Am J Hum Genet 76(3):478-92. Epub 2005 Jan 25. 2005
81AURKB, PARP1
Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage.
Monaco L, Kolthur-Seetharam U, Loury R, Murcia JM, de Murcia G, Sassone-Corsi P.
Proc Natl Acad Sci U S A 102(40):14244-8. Epub 2005 Sep 22. 2005
82PARP1, TNKS
Tankyrase-1 overexpression reduces genotoxin-induced cell death by inhibiting PARP1.
Yeh TY, Sbodio JI, Nguyen MT, Meyer TN, Lee RM, Chi NW.
Mol Cell Biochem 276(1-2):183-92. 2005
83APTX, XRCC1, TP53, PARP1
Aprataxin, a novel protein that protects against genotoxic stress.
Gueven N, Becherel OJ, Kijas AW, Chen P, Howe O, Rudolph JH, Gatti R, Date H, Onodera O, Taucher-Scholz G, Lavin MF.
Hum Mol Genet 13(10):1081-93. Epub 2004 Mar 25. 2004
84TNKS, TERF2, TINF2, PARP1
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex.
Ye JZ, de Lange T.
Nat Genet 36(6):618-23. Epub 2004 May 09. 2004
85PARP8, PARP9, PARP14, PARP15, PARP16, PARP6, PARP11, PARP10, PARP1, PARP2
The PARP superfamily.
Ame JC, Spenlehauer C, de Murcia G.
Bioessays 26(8):882-93. Review. 2004
86PARP1, PARP2
Poly(ADP-ribose) reactivates stalled DNA topoisomerase I and Induces DNA strand break resealing.
Malanga M, Althaus FR.
J Biol Chem 279(7):5244-8. Epub 2003 Dec 29. 2004
87TERF2IP, TERF1, TERF1, PARP1
The human Rap1 protein complex and modulation of telomere length.
O'Connor MS, Safari A, Liu D, Qin J, Songyang Z.
J Biol Chem 279(27):28585-91. Epub 2004 Apr 20. 2004
88PARP1, XRCC1, APTX
The FHA domain of aprataxin interacts with the C-terminal region of XRCC1.
Date H, Igarashi S, Sano Y, Takahashi T, Takahashi T, Takano H, Tsuji S, Nishizawa M, Onodera O.
Biochem Biophys Res Commun 325(4):1279-85. 2004
89PARP1, RANGAP1, BIRC2, TEGT, MCL1, SENP1
Isolation of differentially expressed genes in NPM-ALK-positive anaplastic large cell lymphoma.
Villalva C, Trempat P, Greenland C, Thomas C, Girard JP, Moebius F, Delsol G, Brousset P.
Br J Haematol 118(3):791-8. 2002
90PARP1
Poly(ADP-ribose) polymerase at active centromeres and neocentromeres at metaphase.
Earle E, Saxena A, MacDonald A, Hudson DF, Shaffer LG, Saffery R, Cancilla MR, Cutts SM, Howman E, Choo KH.
Hum Mol Genet 9(2):187-94 2000
91PARP1, SLEB1
PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus.
Tsao BP, et al.
J Clin Invest 103(8):1135-40. 1999
92PARP2 , PARP3, PARP1
A human Poly(ADP-ribose) polymerase gene family (ADPRTL): cDNA cloning of two novel Poly(ADP-ribose) polymerase homologues.
Johansson M.
Genomics 57(3):442-5. 1999
93PARP1
Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion.
Ha HC, Snyder SH.
Proc Natl Acad Sci U S A 96(24):13978-82 1999
94PARP1, FRA1H, RN5S1@
Assignment of FRA1H common fragile site to human chromosome band 1q42.1 proximal to the nuclear NAD+ADP-ribosyltransferase gene (ADPRT) and to the main 5S rRNA gene locus.
Pelliccia F, et al.
Cytogenet Cell Genet 82 : 121-122. 1998
95PARP1, TH
Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2).
De Benedictis G, et al.
Eur J Hum Genet 6 : 534-541. 1998
96PARP1, CASP3
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis.
Nicholson DW, Ali A, Thornberry NA, Vaillancourt JP, Ding CK, Gallant M, Gareau Y, Griffin PR, Labelle M, Lazebnik YA, et al.
Nature 376(6535):37-43. 1995
97PARP1
Dinucleotide repeat polymorphism at the human Poly (ADP-Ribose) polymerase gene (PPOL).
Fougerousse F, et al.
Nucleic Acids Res 20 : 1166. 1992
98PARP1
The human poly(ADP-ribose) polymerase nuclear localization signal is a bipartite element functionally separate from DNA binding and catalytic activity.
Schreiber V, Molinete M, Boeuf H, de Murcia G, Ménissier-de Murcia J.
EMBO J 11(9):3263-9. 1992
99PARP1
A mutant allele common to the type 1 adenine phosphoribosyltransferase deficiency in Japanese subjects.
Mimori A, et al.
Am J Hum Genet 48 : 103-107. 1991
100PARP1,PARP1P1,PARP1P2
Chromosomal sublocalization of the gene for human poly (ADP-ribose) polymerase (NAD+ ADP-ribosyltransferase) at 1q41-42.
Zabel BU, et al.
(HGM10) Cytogenet Cell Genet 51 : 1115. 1989
101PARP1,PARP1P1,PARP1P2
Human nuclear NAD+/ADP-ribosyltransferase: localization of the gene on chromosome 1q41-q42 and expression of an active human enzyme in Escherichia coli.
Herzog H, et al.
Proc Natl Acad Sci U S A 86 : 3514-3518. 1989
102PARP1,PARP1P1,PARP1P2
cDNA sequence, protein structure, and chromosomal location of the human gene for poly (ADP-ribose) polymerase.
Cherney BW, et al.
Proc Natl Acad Sci U S A 84 : 8370-8374. 1987
103PARP1,PARP1P1,PARP1P2
Human poly(ADP-ribose) polymerase sequences are located on chromosomes 1,13, and 14.
McBride OW, et al.
(HGM9) Cytogenet Cell Genet 46 : 659. 1987
104PARP1
Cloning and expression of cDNA for human poly(ADP-ribose) polymerase.
Alkhatib HM, et al.
Proc Natl Acad Sci U S A 84 : 1224-1228. 1987