1 | PAPPA, STC1, STC2
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| The proteolytic activity of pregnancy-associated plasma protein-A is potentially regulated by stanniocalcin-1 and -2 during human ovarian follicle development.
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| Jepsen MR, Kløverpris S, Bøtkjær JA, Wissing ML, Andersen CY, Oxvig C.
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| Hum Reprod 31(4):866-74. doi: 10.1093/humrep/dew013. Epub 2016 Feb 13.
2016
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2 | PAPPA, STC2
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| Stanniocalcin-2 inhibits mammalian growth by proteolytic inhibition of the insulin-like growth factor axis.
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| Jepsen MR, Kløverpris S, Mikkelsen JH, Pedersen JH, Füchtbauer EM, Laursen LS, Oxvig C.
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| J Biol Chem 290(6):3430-9. doi: 10.1074/jbc.M114.611665. Epub 2014 Dec 22.
2015
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3 | IGFBP4, IGFBP5, PAPPA
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| IGF dependent modulation of IGF binding protein (IGFBP) proteolysis by pregnancy-associated plasma protein-A (PAPP-A): multiple PAPP-A-IGFBP interaction sites.
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| Gaidamauskas E, Gyrup C, Boldt HB, Schack VR, Overgaard MT, Laursen LS, Oxvig C.
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| Biochim Biophys Acta 1830(3):2701-9.
2013
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4 | PAPPA, PAPPA2
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| A robust immunoassay for pregnancy-associated plasma protein-A2 based on analysis of circulating antigen: establishment of normal ranges in pregnancy.
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| Kløverpris S, Gaidamauskas E, Rasmussen LC, Overgaard MT, Kronborg C, Knudsen UB, Christiansen M, Kumar A, Oxvig C.
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| Mol Hum Reprod ol Hum Reprod. 2013 Jul 8. [Epub ahead of print]
2013
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5 | PAPPA
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| Constitutive expression of pregnancy-associated plasma protein-A in arterial smooth muscle reduces the vascular response to injury in vivo.
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| Bale LK, Resch ZT, Harstad SL, Overgaard MT, Conover CA.
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| Am J Physiol Endocrinol Metab 304(2):E139-44. doi: 10.1152/ajpendo.00376.2012. Epub 2012 Nov 20.
2013
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6 | PAPPA
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| Protein secretion is required for pregnancy-associated plasma protein-A to promote lung cancer growth in vivo.
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| Pan H, Hanada S, Zhao J, Mao L, Ma MZ.
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| PLoS One 7(11):e48799. doi: 10.1371/journal.pone.0048799. Epub 2012 Nov 9.
2012
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7 | PAPPA
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| Homodimeric pregnancy-associated plasma protein-A in normal human placenta of first and third trimester of pregnancy: biochemical and morphological observations.
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| D'Elia P, Marzioni D, Castellucci M, Mocci C, Pala A.
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| Placenta 33(11):942-5. doi: 10.1016/j.placenta.2012.09.003. Epub 2012 Sep 23.
2012
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8 | PAPPA
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| Increase in serum pregnancy-associated plasma protein-A is correlated with increase in cardiovascular risk factors in adult patients with growth hormone deficiency.
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| Li L, Ren W, Li J, Liu J, Wang L, Zheng X, Liu D, Li S, Souvenir R, Tang J.
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| Endocrine 42(2):375-81. Epub 2012 May 29.
2012
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9 | CETP, LPL, MTHFR, NOS3, OLR1, PAPPA, SERPINE1
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| Candidate gene polymorphisms and the 9p21 locus in acute coronary syndromes.
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| Tousoulis D, Briasoulis A, Papageorgiou N, Antoniades C, Stefanadis C.
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| Trends Mol Med rends Mol Med. 2008 Sep 9. [Epub ahead of print]
2008
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10 | IGFBP4, PAPPA
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| A substrate specificity-determining unit of three Lin12-Notch repeat modules is formed in trans within the pappalysin-1 dimer and requires a sequence stretch C-terminal to the third module.
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| Weyer K, Boldt HB, Poulsen CB, Kjaer-Sorensen K, Gyrup C, Oxvig C.
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| J Biol Chem 282(15):10988-99. Epub 2007 Feb 21.
2007
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11 | PAPPA
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| Substrate specificity of a metalloprotease of the pappalysin family revealed by an inhibitor and a product complex.
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| García-Castellanos R, Tallant C, Marrero A, Solà M, Baumann U, Gomis-Rüth FX.
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| Arch Biochem Biophys 457(1):57-72. Epub 2006 Oct 24.
2007
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12 | PAPPA, PRG2
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| Cell surface detachment of pregnancy-associated plasma protein-A requires the formation of intermolecular proteinase-inhibitor disulfide bonds and glycosaminoglycan covalently bound to the inhibitor.
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| Glerup S, Kløverpris S, Laursen LS, Dagnaes-Hansen F, Thiel S, Conover CA, Oxvig C.
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| J Biol Chem 282(3):1769-78. Epub 2006 Dec 4.
2007
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13 | PAPPA
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| Pregnancy-associated plasma protein-A regulates myoblast proliferation and differentiation through an insulin-like growth factor-dependent mechanism.
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| Kumar A, Mohan S, Newton J, Rehage M, Tran K, Baylink DJ, Qin X.
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| J Biol Chem 280(45):37782-9. Epub 2005 Aug 22. 2005
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14 | PAPPA, DIPAS
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| Identification of two novel human genes, DIPLA1 and DIPAS, expressed in placenta tissue.
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| Garcia J, Castrillo JL.
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| Gene 344:241-50. Epub 2004 Nov 25. 2005
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15 | FRA9E, PAPPA
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| Characterization of the common fragile site FRA9E and its potential role in ovarian cancer.
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| Callahan G, Denison SR, Phillips LA, Shridhar V, Smith DI.
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| Oncogene 22(4):590-601. 2003
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16 | PAPPA
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| Assignment of the human gene for pregnancy-associated plasma protein A (PAPPA) to 9q33.1 by fluorescence in situ hybridization to mitotic and meiotic chromosomes.
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| Silahtaroglu AN, et al.
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| Cytogenet Cell Genet 62 : 214-216. 1993
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