Citations for
1PAPPA, STC1, STC2
The proteolytic activity of pregnancy-associated plasma protein-A is potentially regulated by stanniocalcin-1 and -2 during human ovarian follicle development.
Jepsen MR, Kløverpris S, Bøtkjær JA, Wissing ML, Andersen CY, Oxvig C.
Hum Reprod 31(4):866-74. doi: 10.1093/humrep/dew013. Epub 2016 Feb 13. 2016
2PAPPA, STC2
Stanniocalcin-2 inhibits mammalian growth by proteolytic inhibition of the insulin-like growth factor axis.
Jepsen MR, Kløverpris S, Mikkelsen JH, Pedersen JH, Füchtbauer EM, Laursen LS, Oxvig C.
J Biol Chem 290(6):3430-9. doi: 10.1074/jbc.M114.611665. Epub 2014 Dec 22. 2015
3IGFBP4, IGFBP5, PAPPA
IGF dependent modulation of IGF binding protein (IGFBP) proteolysis by pregnancy-associated plasma protein-A (PAPP-A): multiple PAPP-A-IGFBP interaction sites.
Gaidamauskas E, Gyrup C, Boldt HB, Schack VR, Overgaard MT, Laursen LS, Oxvig C.
Biochim Biophys Acta 1830(3):2701-9. 2013
4PAPPA, PAPPA2
A robust immunoassay for pregnancy-associated plasma protein-A2 based on analysis of circulating antigen: establishment of normal ranges in pregnancy.
Kløverpris S, Gaidamauskas E, Rasmussen LC, Overgaard MT, Kronborg C, Knudsen UB, Christiansen M, Kumar A, Oxvig C.
Mol Hum Reprod ol Hum Reprod. 2013 Jul 8. [Epub ahead of print] 2013
5PAPPA
Constitutive expression of pregnancy-associated plasma protein-A in arterial smooth muscle reduces the vascular response to injury in vivo.
Bale LK, Resch ZT, Harstad SL, Overgaard MT, Conover CA.
Am J Physiol Endocrinol Metab 304(2):E139-44. doi: 10.1152/ajpendo.00376.2012. Epub 2012 Nov 20. 2013
6PAPPA
Protein secretion is required for pregnancy-associated plasma protein-A to promote lung cancer growth in vivo.
Pan H, Hanada S, Zhao J, Mao L, Ma MZ.
PLoS One 7(11):e48799. doi: 10.1371/journal.pone.0048799. Epub 2012 Nov 9. 2012
7PAPPA
Homodimeric pregnancy-associated plasma protein-A in normal human placenta of first and third trimester of pregnancy: biochemical and morphological observations.
D'Elia P, Marzioni D, Castellucci M, Mocci C, Pala A.
Placenta 33(11):942-5. doi: 10.1016/j.placenta.2012.09.003. Epub 2012 Sep 23. 2012
8PAPPA
Increase in serum pregnancy-associated plasma protein-A is correlated with increase in cardiovascular risk factors in adult patients with growth hormone deficiency.
Li L, Ren W, Li J, Liu J, Wang L, Zheng X, Liu D, Li S, Souvenir R, Tang J.
Endocrine 42(2):375-81. Epub 2012 May 29. 2012
9CETP, LPL, MTHFR, NOS3, OLR1, PAPPA, SERPINE1
Candidate gene polymorphisms and the 9p21 locus in acute coronary syndromes.
Tousoulis D, Briasoulis A, Papageorgiou N, Antoniades C, Stefanadis C.
Trends Mol Med rends Mol Med. 2008 Sep 9. [Epub ahead of print] 2008
10IGFBP4, PAPPA
A substrate specificity-determining unit of three Lin12-Notch repeat modules is formed in trans within the pappalysin-1 dimer and requires a sequence stretch C-terminal to the third module.
Weyer K, Boldt HB, Poulsen CB, Kjaer-Sorensen K, Gyrup C, Oxvig C.
J Biol Chem 282(15):10988-99. Epub 2007 Feb 21. 2007
11PAPPA
Substrate specificity of a metalloprotease of the pappalysin family revealed by an inhibitor and a product complex.
García-Castellanos R, Tallant C, Marrero A, Solà M, Baumann U, Gomis-Rüth FX.
Arch Biochem Biophys 457(1):57-72. Epub 2006 Oct 24. 2007
12PAPPA, PRG2
Cell surface detachment of pregnancy-associated plasma protein-A requires the formation of intermolecular proteinase-inhibitor disulfide bonds and glycosaminoglycan covalently bound to the inhibitor.
Glerup S, Kløverpris S, Laursen LS, Dagnaes-Hansen F, Thiel S, Conover CA, Oxvig C.
J Biol Chem 282(3):1769-78. Epub 2006 Dec 4. 2007
13PAPPA
Pregnancy-associated plasma protein-A regulates myoblast proliferation and differentiation through an insulin-like growth factor-dependent mechanism.
Kumar A, Mohan S, Newton J, Rehage M, Tran K, Baylink DJ, Qin X.
J Biol Chem 280(45):37782-9. Epub 2005 Aug 22. 2005
14PAPPA, DIPAS
Identification of two novel human genes, DIPLA1 and DIPAS, expressed in placenta tissue.
Garcia J, Castrillo JL.
Gene 344:241-50. Epub 2004 Nov 25. 2005
15FRA9E, PAPPA
Characterization of the common fragile site FRA9E and its potential role in ovarian cancer.
Callahan G, Denison SR, Phillips LA, Shridhar V, Smith DI.
Oncogene 22(4):590-601. 2003
16PAPPA
Assignment of the human gene for pregnancy-associated plasma protein A (PAPPA) to 9q33.1 by fluorescence in situ hybridization to mitotic and meiotic chromosomes.
Silahtaroglu AN, et al.
Cytogenet Cell Genet 62 : 214-216. 1993