Citations for
A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis.
Carmona FD, Vaglio A, Mackie SL, Hernández-Rodríguez J, Monach PA, Castañeda S, Solans R, Morado IC, Narváez J, Ramentol-Sintas M, Pease CT, Dasgupta B, Watts R, Khalidi N, Langford CA, Ytterberg S, Boiardi L, Beretta L, Govoni M, Emmi G, Bonatti F, Cimmino MA, Witte T, Neumann T, Holle J, Schönau V, Sailler L, Papo T, Haroche J, Mahr A, Mouthon L, Molberg Ø, Diamantopoulos AP, Voskuyl A, Brouwer E, Daikeler T, Berger CT, Molloy ES, O'Neill L, Blockmans D, Lie BA, Mclaren P, Vyse TJ, Wijmenga C, Allanore Y, Koeleman BP; Spanish CGA Group.
Am J Hum Genet 100(1):64-74. doi: 10.1016/j.ajhg.2016.11.013. 2017
2MYP25, P4HA2
Mutations of P4HA2 encoding prolyl 4-hydroxylase 2 are associated with nonsyndromic high myopia.
Guo H, Tong P, Liu Y, Xia L, Wang T, Tian Q, Li Y, Hu Y, Zheng Y, Jin X, Li Y, Xiong W, Tang B, Feng Y, Li J, Pan Q, Hu Z, Xia K.
Genet Med 17(4):300-6. doi: 10.1038/gim.2015.28. 2015
Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition.
Xiong G, Deng L, Zhu J, Rychahou PG, Xu R.
BMC Cancer 14:1. doi: 10.1186/1471-2407-14-1. 2014
Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts.
Gilkes DM, Bajpai S, Chaturvedi P, Wirtz D, Semenza GL.
J Biol Chem 288(15):10819-29. doi: 10.1074/jbc.M112.442939. 2013
Profiling and comparative analysis of glycoproteins in Hs578BST and Hs578T and investigation of prolyl 4-hydroxylase alpha polypeptide II expression and influence in breast cancer cells.
Pan PW, Zhang Q, Bai F, Hou J, Bai G.
Biochemistry (Mosc) 77(5):539-45. doi: 10.1134/S000629791205015X. 2012
Activation of hypoxia-inducible factor-1 via prolyl-4 hydoxylase-2 gene silencing attenuates acute inflammatory responses in postischemic myocardium.
Natarajan R, Salloum FN, Fisher BJ, Ownby ED, Kukreja RC, Fowler AA 3rd.
Am J Physiol Heart Circ Physiol 293(3):H1571-80. 2007
p53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase.
Teodoro JG, Parker AE, Zhu X, Green MR.
Science 313(5789):968-71. 2006
The peptide-substrate-binding domain of human collagen prolyl 4-hydroxylases. Backbone assignments, secondary structure, and binding of proline-rich peptides.
Hieta R, Kukkola L, Permi P, Pirilä P, Kivirikko KI, Kilpeläinen I, Myllyharju J.
J Biol Chem 278(37):34966-74. 2003
Characterization of the human and mouse genes for the alpha subunit of type II prolyl 4-hydroxylase. Identification of a previously unknown alternatively spliced exon and its expression in various tissues.
Nokelainen M, Nissi R, Kukkola L, Helaakoski T, Myllyharju J.
Eur J Biochem 268(20):5300-9. 2001
10P4HA1, P4HA2, P4HB
Identification of a novel proline-rich peptide-binding domain in prolyl 4-hydroxylase.
Myllyharju J, et al.
EMBO J 18 : 306-312. 1999
Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region.
Frazer KA, Ueda Y, Zhu Y, Gifford VR, Garofalo MR, Mohandas N, Martin CH, Palazzolo MJ, Cheng JF, Rubin EM.
Genome Res 7 : 495-512. 1997
12COL13A1, P4HA1, P4HA2
The order and transcriptional orientation of the human COL13A1 and P4HA genes on chromosome 10 long arm determined by high-resolution FISH.
Horelli-Kuitunen N, Kvist AP, Helaakoski T, Kivirikko K, Pihlajaniemi T, Palotie A.
Genomics 46(2):299-302. 1997