1 | CEBPB, P2RY2
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| P2Y(2) receptor expression is regulated by C/EBP¦Â during inflammation in intestinal epithelial cells.
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| Degagn¨¦ E, Turgeon N, Moore-Gagn¨¦ J, Asselin C, Gendron FP.
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| FEBS J 279(16):2957-65. doi: 10.1111/j.1742-4658.2012.08676.x. Epub 2012 Jul 16.
2012
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2 | CEBPB, P2RY2
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| P2Y(2) receptor expression is regulated by C/EBPbeta during inflammation in intestinal epithelial cells.
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| Degagné E, Turgeon N, Moore-Gagné J, Asselin C, Gendron FP.
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| FEBS J 279(16):2957-65. doi: 10.1111/j.1742-4658.2012.08676.x. Epub 2012 Jul 16.
2012
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3 | P2RY1, P2RY2
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| Activation of P2Y1 and P2Y2 receptors induces chloride secretion via calcium-activated chloride channels in kidney inner medullary collecting duct cells.
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| Rajagopal M, Kathpalia PP, Thomas SV, Pao AC.
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| Am J Physiol Renal Physiol 301(3):F544-53. doi: 10.1152/ajprenal.00709.2010. Epub 2011 Jun 8.
2011
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4 | P2RY2
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| The P2Y(2) nucleotide receptor mediates tissue factor expression in human coronary artery endothelial cells.
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| Ding L, Ma W, Littmann T, Camp R, Shen J.
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| J Biol Chem 286(30):27027-38. doi: 10.1074/jbc.M111.235176. Epub 2011 Jun 7.
2011
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5 | ADRBK1, P2RY2
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| P2Y(2) receptors and GRK2 are involved in oscillatory fluid flow induced ERK1/2 responses in chondrocytes.
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| Xing Y, Gu Y, Gomes RR Jr, You J.
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| J Orthop Res 29(6):828-33. doi: 10.1002/jor.21319. Epub 2010 Dec 23. 2011
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6 | P2RY2
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| Purinergic P2Y2 receptors mediate rapid Ca(2+) mobilization, membrane hyperpolarization and nitric oxide production in human vascular endothelial cells.
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| Raqeeb A, Sheng J, Ao N, Braun AP.
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| Cell Calcium 49(4):240-8. doi: 10.1016/j.ceca.2011.02.008. Epub 2011 Mar 16.
2011
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7 | OTOP1, P2RY2
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| Missense mutations in Otopetrin 1 affect subcellular localization and inhibition of purinergic signaling in vestibular supporting cells.
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| Kim E, Hyrc KL, Speck J, Salles FT, Lundberg YW, Goldberg MP, Kachar B, Warchol ME, Ornitz DM.
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| Mol Cell Neurosci 46(3):655-61. doi: 10.1016/j.mcn.2011.01.005. Epub 2011 Jan 12.
2011
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8 | P2RY2
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| The P2Y2 receptor mediates the epithelial injury response and cell migration.
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| Boucher I, Rich C, Lee A, Marcincin M, Trinkaus-Randall V.
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| Am J Physiol Cell Physiol 299(2):C411-21. doi: 10.1152/ajpcell.00100.2009. Epub 2010 Apr 28.
2010
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9 | P2RY2
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| P2Y2 nucleotide receptors mediate metalloprotease-dependent phosphorylation of epidermal growth factor receptor and ErbB3 in human salivary gland cells.
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| Ratchford AM, Baker OJ, Camden JM, Rikka S, Petris MJ, Seye CI, Erb L, Weisman GA.
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| J Biol Chem 285(10):7545-55. doi: 10.1074/jbc.M109.078170. Epub 2010 Jan 11.
2010
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10 | P2RY2
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| UTP controls cell surface distribution and vasomotor activity of the human P2Y2 receptor through an epidermal growth factor receptor-transregulated mechanism.
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| Norambuena A, Palma F, Poblete MI, Donoso MV, Pardo E, González A, Huidobro-Toro JP.
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| J Biol Chem 285(5):2940-50. doi: 10.1074/jbc.M109.081166. Epub 2009 Dec 7.
2010
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11 | P2RY2
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| P2Y receptors mediate Ca2+ signaling in duodenocytes and contribute to duodenal mucosal bicarbonate secretion.
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| Dong X, Smoll EJ, Ko KH, Lee J, Chow JY, Kim HD, Insel PA, Dong H.
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| Am J Physiol Gastrointest Liver Physiol 296(2):G424-32. doi: 10.1152/ajpgi.90314.2008. Epub 2008 Dec 12.
2009
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12 | P2RY2, P2RY6
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| Concomitant activation of P2Y(2) and P2Y(6) receptors on monocytes is required for TLR1/2-induced neutrophil migration by regulating IL-8 secretion.
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| Ben Yebdri F, Kukulski F, Tremblay A, Sévigny J.
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| Eur J Immunol 39(10):2885-94. doi: 10.1002/eji.200939347.
2009
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13 | P2RY2
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| P2Y2 receptor desensitization on single endothelial cells.
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| Sanabria P, Ross E, Ramirez E, Colon K, Hernandez M, Maldonado HM, Silva WI, Jimenez-Rivera CA, Gonzalez FA.
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| Endothelium 15(1):43-51.
2008
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14 | P2RY2
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| Selective loss of P2Y2 nucleotide receptor immunoreactivity is associated with Alzheimer's disease neuropathology.
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| Lai MK, Tan MG, Kirvell S, Hobbs C, Lee J, Esiri MM, Chen CP, Francis PT.
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| J Neural Transm 115(8):1165-72. Epub 2008 May 28.
2008
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15 | P2RY2
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| Binding of the P2Y2 nucleotide receptor to filamin A regulates migration of vascular smooth muscle cells.
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| Yu N, Erb L, Shivaji R, Weisman GA, Seye CI.
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| Circ Res 102(5):581-8. doi: 10.1161/CIRCRESAHA.107.162271. Epub 2008 Jan 17.
2008
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16 | P2RY2, ADORA3
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| ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors.
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| Chen Y, Corriden R, Inoue Y, Yip L, Hashiguchi N, Zinkernagel A, Nizet V, Insel PA, Junger WG.
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| Science 314(5806):1792-5. 2006
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17 | P2RY2
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| P2Y2 receptor activates nerve growth factor/TrkA signaling to enhance neuronal differentiation.
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| Arthur DB, Akassoglou K, Insel PA.
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| Proc Natl Acad Sci U S A 102(52):19138-43. Epub 2005 Dec 19. 2005
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18 | P2RY2
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| The apical targeting signal of the P2Y2 receptor is located in its first extracellular loop.
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| Qi AD, Wolff SC, Nicholas RA.
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| J Biol Chem 280(32):29169-75. Epub 2005 May 20.
2005
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19 | ARAP1, ARHGEF17, P2RY2, P2RY6, PDE2A, RELT
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| Refined genetic mapping of autosomal recessive chronic distal spinal muscular atrophy to chromosome 11q13.3 and evidence of linkage disequilibrium in European families.
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| Viollet L, Zarhrate M, Maystadt I, Estournet-Mathiaut B, Barois A, Desguerre I, Mayer M, Chabrol B, LeHeup B, Cusin V, Billette De Villemeur T, Bonneau D, Saugier-Veber P, Touzery-De Villepin A, Delaubier A, Kaplan J, Jeanpierre M, Feingold J, Munnich A.
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| Eur J Hum Genet 12(6):483-8. 2004
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20 | P2RY2
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| Molecular mechanism of nucleotide-induced primary granule release in human neutrophils: role for the P2Y2 receptor.
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| Meshki J, Tuluc F, Bredetean O, Ding Z, Kunapuli SP.
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| Am J Physiol Cell Physiol 286(2):C264-71. Epub 2003 Nov 12.
2004
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21 | LTB4R, P2RY6, P2RY1, P2RY2
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| Chromosomal localization of the human P2y6 purinoceptor gene and phylogenetic analysis of the P2y purinoceptor family.
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| Somers GR, Hammet F, Woollatt E, Richards RI, Southey MC, Venter DJ.
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| Genomics 44(1):127-30. 1997
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22 | P2RY2, P2RY6
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| Colocalization of P2Y2 and P2Y6 receptor genes at human chromosome 11q13.3-14.1.
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| Pidlaoan LV, et al.
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| Somat Cell Mol Genet 23 : 291-296. 1997
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23 | P2RY2
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| Identification and characterization of P2Y2 nucleotide receptors in human retinal pigment epithelial cells.
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| Sullivan DM, Erb L, Anglade E, Weisman GA, Turner JT, Csaky KG.
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| J Neurosci Res 49(1):43-52.
1997
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24 | P2RY2
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| Mapping of the P2U purinergic receptor gene to human chromosome 11q13.5-14.1.
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| Dasari VR, et al.
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| Somat Cell Mol Genet 22 : 75-79. 1996
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25 | P2RY2, P2RY4, LTB4R
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| Molecular cloning of a novel P2 purinoceptor from human erythroleukemia cells.
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| Akbar GKM, et al.
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| J Biol Chem 271 : 18363-18367. 1996
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26 | P2RY2
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| Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy.
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| Parr CE, et al.
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| Proc Natl Acad Sci U S A 91 : 3275-3279. 1994
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