Citations for
1P2RY12, SLC9A3R1
Arrestin scaffolds NHERF1 to the P2Y12 receptor to regulate receptor internalization.
Nisar SP, Cunningham M, Saxena K, Pope RJ, Kelly E, Mundell SJ.
J Biol Chem 287(29):24505-15. doi: 10.1074/jbc.M112.347104. Epub 2012 May 18. 2012
2P2RY12
The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling.
Su X, Floyd DH, Hughes A, Xiang J, Schneider JG, Uluckan O, Heller E, Deng H, Zou W, Craft CS, Wu K, Hirbe AC, Grabowska D, Eagleton MC, Townsley S, Collins L, Piwnica-Worms D, Steinberg TH, Novack DV, Conley PB, Hurchla MA, Rogers M, Weilbaecher KN.
J Clin Invest 122(10):3579-92. doi: 10.1172/JCI38576. Epub 2012 Sep 17. 2012
3ARF6, P2RY1, P2RY12
ARF6-dependent regulation of P2Y receptor traffic and function in human platelets.
Kanamarlapudi V, Owens SE, Saha K, Pope RJ, Mundell SJ.
PLoS One 7(8):e43532. doi: 10.1371/journal.pone.0043532. Epub 2012 Aug 16. 2012
4P2RY1, P2RY12, P2RY6
P2Y receptors regulate proliferation of human pancreatic duct epithelial cells.
Ko T, An HJ, Ji YG, Kim OJ, Lee DH.
Pancreas 41(5):797-803. doi: 10.1097/MPA.0b013e31823ba3b3. 2012
5ADARA2A, P2RY1, P2RY12
Functional interaction between purinergic receptors: effect of ligands for A2A and P2Y12 receptors on P2Y1 receptor function.
Suzuki T, Obara Y, Moriya T, Nakata H, Nakahata N.
FEBS Lett 585(24):3978-84. doi: 10.1016/j.febslet.2011.10.050. Epub 2011 Nov 10. 2011
6P2RY12
An intact PDZ motif is essential for correct P2Y12 purinoceptor traffic in human platelets.
Nisar S, Daly ME, Federici AB, Artoni A, Mumford AD, Watson SP, Mundell SJ.
Blood 118(20):5641-51. doi: 10.1182/blood-2011-02-336826. Epub 2011 Sep 21. 2011
7P2RY12
Contribution of the P2Y12 receptor-mediated pathway to platelet hyperreactivity in hypercholesterolemia.
Nagy B Jr, Jin J, Ashby B, Reilly MP, Kunapuli SP.
J Thromb Haemost 9(4):810-9. doi: 10.1111/j.1538-7836.2011.04217.x. 2011
8P2RY12
P2Y12 receptor in platelet activation.
Kim S, Kunapuli SP.
Platelets 22(1):56-60. doi: 10.3109/09537104.2010.497231. Review. 2011
9P2RY12
Regulation of functionally active P2Y12 ADP receptors by thrombin in human smooth muscle cells and the presence of P2Y12 in carotid artery lesions.
Rauch BH, Rosenkranz AC, Ermler S, Böhm A, Driessen J, Fischer JW, Sugidachi A, Jakubowski JA, Schrör K.
Arterioscler Thromb Vasc Biol 30(12):2434-42. doi: 10.1161/ATVBAHA.110.213702. Epub 2010 Nov 11. 2010
10P2RY12
Mutational analysis of residues important for ligand interaction with the human P2Y(12) receptor.
Mao Y, Zhang L, Jin J, Ashby B, Kunapuli SP.
Eur J Pharmacol 644(1-3):10-6. doi: 10.1016/j.ejphar.2010.06.023. Epub 2010 Jun 30. 2010
11P2RY12
Stabilizing role of platelet P2Y(12) receptors in shear-dependent thrombus formation on ruptured plaques.
Nergiz-Unal R, Cosemans JM, Feijge MA, van der Meijden PE, Storey RF, van Giezen JJ, oude Egbrink MG, Heemskerk JW, Kuijpers MJ.
PLoS One 5(4):e10130. doi: 10.1371/journal.pone.0010130. 2010
12P2RY12
P2Y12 receptor protein in cortical gray matter lesions in multiple sclerosis.
Amadio S, Montilli C, Magliozzi R, Bernardi G, Reynolds R, Volonté C.
Cereb Cortex 20(6):1263-73. doi: 10.1093/cercor/bhp193. Epub 2009 Sep 26. 2010
13P2RY1, P2RY12, PTGS2, UGT1A6
The genetics of antiplatelet drug resistance.
Feher G, Feher A, Pusch G, Lupkovics G, Szapary L, Papp E.
Clin Genet 75(1):1-18. Epub 2008 Nov 29. Review. 2009
14P2RY12
Platelet P2Y(12) receptor influences the vessel wall response to arterial injury and thrombosis.
Evans DJ, Jackman LE, Chamberlain J, Crosdale DJ, Judge HM, Jetha K, Norman KE, Francis SE, Storey RF.
Circulation 119(1):116-22. doi: 10.1161/CIRCULATIONAHA.107.762690. Epub 2008 Dec 22. 2009
15P2RY12
P2Y12 receptors in spinal microglia are required for neuropathic pain after peripheral nerve injury.
Tozaki-Saitoh H, Tsuda M, Miyata H, Ueda K, Kohsaka S, Inoue K.
J Neurosci 28(19):4949-56. doi: 10.1523/JNEUROSCI.0323-08.2008. 2008
16P2RX4, P2RY12
Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis.
Ohsawa K, Irino Y, Nakamura Y, Akazawa C, Inoue K, Kohsaka S.
Glia 55(6):604-16. 2007
17P2RY12
The P2Y12 receptor regulates microglial activation by extracellular nucleotides.
Haynes SE, Hollopeter G, Yang G, Kurpius D, Dailey ME, Gan WB, Julius D.
Nat Neurosci 9(12):1512-9. Epub 2006 Nov 19. 2006
18P2RY12
Evidence that the purinergic receptor P2Y12 potentiates platelet shape change by a Rho kinase-dependent mechanism.
Hardy AR, Hill DJ, Poole AW.
Platelets 16(7):415-29. 2005
19P2RY1, P2RY12
P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms.
Hardy AR, Conley PB, Luo J, Benovic JL, Poole AW, Mundell SJ.
Blood 105(9):3552-60. Epub 2005 Jan 21. 2005
20P2RY1, P2RY12
Reciprocal cross-talk between P2Y1 and P2Y12 receptors at the level of calcium signaling in human platelets.
Hardy AR, Jones ML, Mundell SJ, Poole AW.
Blood 104(6):1745-52. Epub 2004 Jun 8. 2004
21P2RY12
Identification of the platelet ADP receptor targeted by antithrombotic drugs.
Hollopeter G, Jantzen HM, Vincent D, Li G, England L, Ramakrishnan V, Yang RB, Nurden P, Nurden A, Julius D, Conley PB.
Nature 409(6817):202-7. 2001
22P2RY12
An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function.
Nurden P, Savi P, Heilmann E, Bihour C, Herbert JM, Maffrand JP, Nurden A.
J Clin Invest 95(4):1612-22. 1995